Angioimmunoblastic lymphadenopathy: a T-cell deficiency.

Abstract:

:The case of a 49-year-old man with the diagnosis of angioimmunoblastic lymphadenopathy is reported. The patient survived a stormy clinical course. The corticosteroids improved dramatically the clinical picture although the patient developed a staphylococcal septicemia. Before treatment immunological studies were done including quantitation of B and T-cells, antigen stimulation of lymphocytes in vitro, skin tests and skin window. Impairment of cell mediated immunity, decreased T-lymphocytes and increased B-lymphocytes were found. A decreased migration of lymphocytes in the skin window was also found compatible with immunosuppression. A possible presumptive pathogenetic mechanism is described although the cause of this recently described entity remains unknown.

journal_name

Cancer

journal_title

Cancer

authors

Kosmidis PA,Axelrod AR,Palacas C,Stahl M

doi

10.1002/1097-0142(197808)42:2<447::aid-cncr2820420

subject

Has Abstract

pub_date

1978-08-01 00:00:00

pages

447-52

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

42

pub_type

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