Cyclophosphamide therapy and interstitial pulmonary fibrosis.

abstract：:Forty-four cases of skin and soft tissue angiosarcoma seen at M. D. Anderson Hospital before 1976 were reviewed. The cases fell into six different clinical groups: scalp-face, 17 cases; postmastectomy, 14 cases; postradiation, 5 cases; leg with vascular stasis, 2 cases; breast, 2 cases; and miscellaneous, 4 cases. In ...

journal_title：Cancer

authors： Maddox JC,Evans HL

更新日期：1981-10-15 00:00:00

abstract：BACKGROUND:Tumor volume in radical prostatectomies can be determined by several different techniques and appears to predict clinical progression. Greatest tumor dimension and area are easily obtained measures that are both correlated with tumor volume. The authors sought to determine whether greatest tumor dimension an...

journal_title：Cancer

authors： Renshaw AA,Richie JP,Loughlin KR,Jiroutek M,Chung A,D'Amico AV

更新日期：1998-08-15 00:00:00

abstract：BACKGROUND:The frequency of RET rearrangements (RET/PTC) in papillary thyroid carcinomas varies significantly according to geographic area, with the greatest incidence reported in the Belarus region, which is iodine-deficient and was contaminated severely after the Chernobyl reactor accident, and with the lowest incide...

journal_title：Cancer

authors： Nakazawa T,Kondo T,Kobayashi Y,Takamura N,Murata S,Kameyama K,Muramatsu A,Ito K,Kobayashi M,Katoh R

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The poor prognosis reported for patients with high-grade glial neoplasms indicates a need for the development of multimodality therapeutic approaches. The addition of chemotherapy has contributed variably to increased survival. The objective of the current study (Southwest Oncology Group [SWOG] 9016) was to ...

journal_title：Cancer

authors： Blumenthal DT,Rankin C,Eyre HJ,Livingston RB,Spence AM,Stelzer KJ,Rushing EJ,Berger MS,Rivkin SE,Cohn AL,Petersdorf SH

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Hypoxia inducible factor-1 (HIF-1) plays a critical role in angiogenesis during vascular development. The authors tested the hypothesis that HIF-1 expression correlates with progression and angiogenesis in brain tumors. METHODS:The authors investigated the expression of the HIF-1alpha and HIF-1beta subunits...

journal_title：Cancer

authors： Zagzag D,Zhong H,Scalzitti JM,Laughner E,Simons JW,Semenza GL

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:The diagnosis of malignant mesothelioma (MM) in serous effusions is difficult but may be achieved by the application of adjuvant methods. METHODS:The authors cytologically diagnosed 33 effusions as suspicious or positive for MM cells by using DNA-image cytometry (DNA-ICM), immunocytochemistry and AgNOR anal...

journal_title：Cancer

authors： Onofre FB,Onofre AS,Pomjanski N,Buckstegge B,Grote HJ,Böcking A

更新日期：2008-06-25 00:00:00

abstract：:Fifty-one cases of acinic cell carcinoma (ACC) arising in major and minor salivary glands are reported (primary sites: parotid 37, submandibular, six, and oral cavity, eight.) These lesions usually produced painless slowly growing masses. Of 49 patients with follow-up information, 17 (35%) developed local recurrences ...

journal_title：Cancer

authors： Perzin KH,LiVolsi VA

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:High-dose methotrexate (MTX) is an important component of current protocols for the treatment of osteosarcoma. Although MTX uptake proceeds primarily through the reduced folate carrier (RFC) protein and efflux occurs via multidrug resistance protein 1 (MRP1), RFC protein expression in osteosarcoma remains un...

journal_title：Cancer

authors： Ifergan I,Meller I,Issakov J,Assaraf YG

更新日期：2003-11-01 00:00:00

abstract：:The urinary neopterin excretion was measured by high-performance liquid chromatography in 417 healthy subjects and in 76 patients with clinically and pathohistologically verified neoplasias of the urinary tract (bladder tumor, carcinoma of the prostate, and renal cell carcinoma). The patients with early tumor stages b...

journal_title：Cancer

authors： Aulitzky W,Frick J,Fuchs D,Hausen A,Reibnegger G,Wachter H

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND:Although breast-conserving therapy (tumor excision, axillary node dissection, and postoperative radiation) for women with breast cancer yields survival and local recurrence rates comparable with those of modified radical mastectomy, studies suggest that postoperative radiation leads to capsular contractures ...

journal_title：Cancer

authors： Guenther JM,Tokita KM,Giuliano AE

更新日期：1994-05-15 00:00:00

abstract：:In 1988, Californians passed Proposition 99, which raised the tobacco tax from 10 cents to 35 cents and allocated 20% of the resulting revenues, approximately $100 million, for tobacco education and 5% for tobacco-related research. Seventy percent was allocated for health care costs and 5% for the environment. In this...

journal_title：Cancer

authors： Martin CB,Beerline D,Breslow L

更新日期：1998-12-15 00:00:00

abstract：:A unique case of malignant histiocytosis (MH) is reported. Its origin from the monocyte-macrophage system was indicated by expression of highly specific myeloid cell markers (My4, MCS2, and cytoplasmic lysozyme), diffuse activity of acid phosphatase and NaF-sensitive alpha-naphthyl acetate esterase, lack of immunologi...

journal_title：Cancer

authors： Kamesaki H,Koya M,Miwa H,Kita K,Doi S,Tatsumi E,Hatanaka M,Uchino H

更新日期：1988-10-01 00:00:00

abstract：:Indirect data supporting a preexisting immunologic impairment in patients with Hodgkin's disease (HD) have been presented in recent years. These immunologic defects are supposed to be related to genetic and/or environmental factors. In this study, 65 first-degree relatives and 12 spouses of 21 consecutive patients wit...

journal_title：Cancer

authors： Merk K,Björkholm M,Tullgren O,Mellstedt H,Holm G

更新日期：1990-11-01 00:00:00

abstract：:Patients with ulcerative colitis are at increased risk of developing adenocarcinoma of the colon. The authors describe a patient whose colonic neoplasm demonstrated histologic characteristics of both an adenocarcinoma and a carcinoid tumor and which was pathologically identical to a appendiceal adenocarcinoid. Because...

journal_title：Cancer

authors： Lyss AP,Thompson JJ,Glick JH

更新日期：1981-08-01 00:00:00

abstract：:Twenty-three leukemic children were studied prospectively to detect chronic effects of therapy. All patients received CNS prophylaxis, including 2400 R cranial irradiation, and intermittent maintenance therapy with intravenous methotrexate, cyclophosphamide and cytosine arabinoside. Neurologic symptoms were observed i...

journal_title：Cancer

authors： McIntosh S,Klatskin EH,O'Brien RT,Aspnes GT,Kammerer BL,Snead C,Kalavsky SM,Pearson HA

更新日期：1976-02-01 00:00:00

abstract：:Bone marrow trephine biopsies were performed on 107 previously untreated patients with Hodgkin's disease (HD). Fifteen patients (14%) exhibited bone marrow involvement. These consisted of two of three patients (67%) with lymphocyte depletion, six of 27 patients (22%) with mixed cellularity, five of 64 patients (8%) wi...

journal_title：Cancer

authors： O'Carroll DI,McKenna RW,Brunning RD

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Cytogenetics and multicolor flow cytometry (MFC) are useful tools for monitoring outcome of treatment in acute myeloid leukemia (AML). However, no data are available regarding the meaning of results when the 2 tests do not agree. METHODS:The authors of this report analyzed 1464 pairs of concurrent cytogenet...

journal_title：Cancer

authors： Fang M,Storer B,Wood B,Gyurkocza B,Sandmaier BM,Appelbaum FR

更新日期：2012-05-01 00:00:00

abstract：:Carcinomas of the pancreas with giant cells are not rare, but those containing osteoclast-like tumor cells are quite unusual. This report documents a pancreatic neoplasm comprising both easily recognizable well-differentiated adenocarcinoma and osteoclast-like tumor. The literature on the "osteoclastoma" of the pancre...

journal_title：Cancer

authors： Trepeta RW,Mathur B,Lagin S,LiVolsi VA

更新日期：1981-11-01 00:00:00

abstract：:A clinicopathologic analysis of 12 cases of a morphologically distinctive non-Hodgkin's malignant lymphoma which appeared to arise from the mantle zones of secondary lymphoid follicles is presented. In lymph node and spleen sections, atypical small lymphoid cells with slightly irregular and indented nuclear contours p...

journal_title：Cancer

authors： Weisenburger DD,Kim H,Rappaport H

更新日期：1982-04-01 00:00:00

abstract：:The adolescent and young adult (AYA) oncology population has seen inferior progress in cancer survival compared with younger children and older adults over the past 25 years. Previously, AYAs had the best survival rates due to the prevalence of highly curable diseases including Hodgkin lymphoma and germ cell tumors, y...

journal_title：Cancer

authors： Burke ME,Albritton K,Marina N

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Methotrexate is readily absorbed from the intestinal tract. When given to patients with urinary diversion to the intestinal tract, methotrexate may be reabsorbed into the circulation, thus increasing its serum concentration and potentially increasing its toxicity. METHODS:Forty-eight patients with transitio...

journal_title：Cancer

authors： Srinivas S,Mahalati K,Freiha FS

更新日期：1998-03-15 00:00:00

abstract：BACKGROUND:Small cell glioblastoma (GBM) is a variant with monomorphous, deceptively bland nuclei that often is misdiagnosed as anaplastic oligodendroglioma. METHODS:To elucidate its clinicopathologic and genetic features, the authors studied 71 adult patients (median age, 57 years), including 22 patients who were ide...

journal_title：Cancer

authors： Perry A,Aldape KD,George DH,Burger PC

更新日期：2004-11-15 00:00:00

abstract：:Standardized incidence ratio for cancer in Norwegian Seventh-Day Adventists compared with the general population was not significantly different from unity (men 91, women 97). Persons converting late in life had a higher incidence than those converting at an earlier age. Respiratory cancers (standardized incidence rat...

journal_title：Cancer

authors： Fønnebø V,Helseth A

更新日期：1991-08-01 00:00:00

abstract：BACKGROUND:Resistance to apoptosis is 1 of the key events that confer chemoresistance and is mediated by the overexpression of antiapoptotic proteins, which inhibit caspase activation. The objective of this study was to evaluate whether the activation of an alternative, caspase-independent cell death pathway could prom...

journal_title：Cancer

authors： Alvero AB,Montagna MK,Chen R,Kim KH,Kyungjin K,Visintin I,Fu HH,Brown D,Mor G

更新日期：2009-07-15 00:00:00

abstract：BACKGROUND:Because patients with germ cell tumors expect an additional life span of around 50 years after successful treatment, attention is now focused on potential long term toxicity. Limited data are available on Leydig cell function in long term survivors. METHODS:The authors measured testosterone, sex hormone bin...

journal_title：Cancer

authors： Gerl A,Mühlbayer D,Hansmann G,Mraz W,Hiddemann W

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Metallothioneins (MT) are endogenous metalloproteins involved in the homeostasis of essential metals and detoxification of toxic metals. Some recent experimental studies suggested tumor resistance to cisdiamminedichloroplatin may be associated with overexpression of MT in the tumor. METHODS:The presence of ...

journal_title：Cancer

authors： Chin JL,Banerjee D,Kadhim SA,Kontozoglou TE,Chauvin PJ,Cherian MG

更新日期：1993-11-15 00:00:00

abstract：BACKGROUND:Most commercial fecal occult blood tests (FOBT) used for colorectal carcinoma screening of Western populations are guaiac-based, manually developed, subjective, and sensitive to dietary components. Preliminary studies demonstrated the unsuitability of these tests for screening a Chinese population. The goal ...

journal_title：Cancer

authors： Wong WM,Lam SK,Cheung KL,Tong TS,Rozen P,Young GP,Chu KW,Ho J,Law WL,Tung HM,Choi HK,Lee YM,Lai KC,Hu WH,Chan CK,Yuen MF,Wong BC

更新日期：2003-05-15 00:00:00

abstract：:One hundred thirty patients with histologically verified primary fibrosarcoma of bone, unassociated with any pre-existent benign bone condition, were treated at Memorial Sloan-Kettering Cancer Center between 1918 and 1973. This series of cases represents approximately 5% of primary malignant bone tumors treated in our...

journal_title：Cancer

authors： Huvos AG,Higinbotham NL

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:Breast conservation is now established treatment for patients with small breast cancers. The authors reviewed a large series of patients with long term follow-up who underwent conservative treatment. Clinical and pathologic factors were analyzed to identify patients at an increased risk of relapse in the bre...

journal_title：Cancer

authors： Dewar JA,Arriagada R,Benhamou S,Benhamou E,Bretel JJ,Pellae-Cosset B,Marin JL,Petit JY,Contesso G,Sarrazin D

更新日期：1995-12-01 00:00:00

abstract：:Sixty-four adult patients with refractory acute lymphocytic leukemia (ALL) received salvage therapy with the vincristine, doxorubicin (Adriamycin, Adria Laboratories, Columbus, OH), and dexamethasone (VAD) regimen consisting of induction chemotherapy with the three agents followed by multiple-agent maintenance therapy...

journal_title：Cancer

authors： Kantarjian HM,Walters RS,Keating MJ,Barlogie B,McCredie KB,Freireich EJ

更新日期：1989-07-01 00:00:00