Abstract:
:A unique case of malignant histiocytosis (MH) is reported. Its origin from the monocyte-macrophage system was indicated by expression of highly specific myeloid cell markers (My4, MCS2, and cytoplasmic lysozyme), diffuse activity of acid phosphatase and NaF-sensitive alpha-naphthyl acetate esterase, lack of immunologic markers specific for other cell lineages, and germ line configuration of the immunoglobulin light chain gene and the T-cell receptor beta-chain gene. Its neoplastic nature was suggested by the single rearranged band of the immunoglobulin heavy chain gene.
journal_name
Cancerjournal_title
Cancerauthors
Kamesaki H,Koya M,Miwa H,Kita K,Doi S,Tatsumi E,Hatanaka M,Uchino Hdoi
10.1002/1097-0142(19881001)62:7<1306::aid-cncr2820subject
Has Abstractpub_date
1988-10-01 00:00:00pages
1306-9issue
7eissn
0008-543Xissn
1097-0142journal_volume
62pub_type
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