Comparison of continuously infused 5-fluorouracil with bolus injection in treatment of patients with colorectal adenocarcinoma.

abstract：BACKGROUND:Breast cancer is the most common cancer and the second leading cause of cancer death among women in the United States; annual breast cancer deaths are exceeded only by those for lung cancer. METHODS:Data from the Surveillance, Epidemiology, and End Results (SEER) program registry of the National Cancer Inst...

journal_title：Cancer

authors： Berg JW,Hutter RV

更新日期：1995-01-01 00:00:00

abstract：:Responding to growing concerns regarding the safety, quality, and efficacy of cancer care in the United States, the Institute of Medicine (IOM) of the National Academy of Sciences commissioned a comprehensive review of cancer care delivery in the US health care system in the late 1990s. The National Cancer Policy Boar...

journal_title：Cancer

authors： Spinks T,Albright HW,Feeley TW,Walters R,Burke TW,Aloia T,Bruera E,Buzdar A,Foxhall L,Hui D,Summers B,Rodriguez A,Dubois R,Shine KI

更新日期：2012-05-15 00:00:00

abstract：:Variation in response rates to chemotherapy and survival in patients with hepatic metastases from colorectal carcinoma may be due to patient selection factors. The prognostic importance of 13 factors were analyzed in 112 patients with only hepatic metastases, who were eligible for hepatic artery infusional chemotherap...

journal_title：Cancer

authors： Kemeny N,Niedzwiecki D,Shurgot B,Oderman P

更新日期：1989-02-15 00:00:00

abstract：:"Bowen's disease" is a clinical and histologic diagnosis describing the lesions (single or multiple) of cutaneous in situ squamous cell carcinoma. The case of a 54-year-old man with 60 such intra-epidermal carcinomas, and a history of arsenic ingestion, is presented. The patient was sensitized to dinitrochlorobenzene ...

journal_title：Cancer

authors： Raaf JH,Krown SE,Pinsky CM,Cunningham-Rundles W,Safai B,Oettgen HF

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:The measurement of estrogen receptors (ER) in breast cancer specimens has traditionally been assessed with a dextran-coated charcoal assay (DCCA). More recently the immunohistochemical staining (IHC) method has gained increasing popularity because of its ability to use fixed tissue, assess needle biopsies, a...

journal_title：Cancer

authors： Alberts SR,Ingle JN,Roche PR,Cha SS,Wold LE,Farr GH Jr,Krook JE,Wieand HS

更新日期：1996-08-15 00:00:00

abstract：BACKGROUND:For this report, the authors comprehensively summarized the existing literature on patients with pineoblastoma and identified the variables and treatments that had an impact patient on outcomes. METHODS:A comprehensive search identified 109 studies that collectively described the outcomes of patients with p...

journal_title：Cancer

authors： Tate M,Sughrue ME,Rutkowski MJ,Kane AJ,Aranda D,McClinton L,McClinton L,Barani IJ,Parsa AT

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:The effectiveness of adjuvant chemotherapy in soft tissue sarcomas remains a matter of controversy. The authors reviewed their experience with 14 patients with localized disease treated with intensive doxorubicin-cisplatin-ifosfamide-based chemotherapy. METHODS:Fourteen patients with newly diagnosed nonmeta...

journal_title：Cancer

authors： Kampe CE,Rosen G,Eilber F,Eckardt J,Lowenbraun S,Foster J,Forscher C,Selch M

更新日期：1993-10-01 00:00:00

abstract：:Regressing atypical histiocytosis (RAH) of skin is a cutaneous noduloulcerative proliferation of atypical neoplastic histiocytes with concomitant polymorphous inflammation, frequently pronounced epidermal hyperplasia, and an unexpectedly indolent biologic course. Spontaneous regression and recurrence without systemic ...

journal_title：Cancer

authors： Flynn KJ,Dehner LP,Gajl-Peczalska KJ,Dahl MV,Ramsay N,Wang N

更新日期：1982-03-01 00:00:00

abstract：:This overview highlights the use of experimental models in selecting monoclonal antibodies and radiolabels with promise for clinical radioimmunotherapy, discusses some of the experimental therapeutic approaches being studies in these models, and reviews some of the limitations of animal models caused by the allometric...

journal_title：Cancer

authors： Wahl RL

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The presence of tumor cells in peritoneal washing cytology specimens taken during surgery affects the staging of many gynecologic malignancies. Peritoneal washings are often collected routinely, even in cases of presumed benign disease. This study was designed to address whether evaluation of these specimens...

journal_title：Cancer

authors： Sharifi S,Ducatman BS,Wang HH,Fraser JL

更新日期：1999-10-25 00:00:00

abstract：METHODS:Between 1983 and 1989, 42 patients with Stage II, III, and IV, node-negative, squamous cell head and neck cancer were treated with concurrent 5-fluorouracil, cisplatin, and radiation therapy. Two courses of chemotherapy with 30 Gy of concurrent radiation therapy were to be followed in all patients by definitive...

journal_title：Cancer

authors： Adelstein DJ,Sharan VM,Damm C,Earle AS,Shah AC,Haria CD,Trey JE,Carter SG,Hines JD

更新日期：1992-12-01 00:00:00

abstract：:This article reviews the clinicopathologic features and the biological behavior of 24 cases of synovial sarcoma that took origin from the cervical prevertebral connective tissue space and manifested as a retropharyngeal tumor or as a palpable mass in the anterior or posterior cervical triangle. The age of the 24 patie...

journal_title：Cancer

authors： Roth JA,Enzinger FM,Tannenbaum M

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:Little is known about the natural growth characteristics of untreated glioblastoma before surgical or therapeutic intervention, because patients are rapidly treated after preliminary radiographic diagnosis. Understanding the growth characteristics of uninhibited human glioblastoma may be useful for character...

journal_title：Cancer

authors： Ellingson BM,Nguyen HN,Lai A,Nechifor RE,Zaw O,Pope WB,Yong WH,Nghiemphu PL,Liau LM,Cloughesy TF

更新日期：2016-06-01 00:00:00

abstract：:A clinicopathologic analysis of 35 cases of lymphocyte predominance Hodgkin's disease (LPHD) was performed, and the relationship between various histologic features and stage at presentation was examined. The series comprised 31 male and 4 female patients with a median age of 32 years. Twenty patients had Ann Arbor St...

journal_title：Cancer

authors： Trudel MA,Krikorian JG,Neiman RS

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:The authors hypothesized that the outcomes for young patients who present with primary osteosarcoma of flat bones or secondary osteosarcoma after other primary malignancies are similar because the sites of these tumors rarely makes them amenable to complete surgical resection. METHODS:The authors reviewed t...

journal_title：Cancer

authors： Pratt CB,Meyer WH,Rao BN,Pappo AS,Fleming ID,Luo X,Cain A,Kaste SC,Shearer PD,Jenkins JJ 3rd

更新日期：1997-09-15 00:00:00

abstract：BACKGROUND:Topoisomerase I inhibitors, like topotecan, have activity in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML). 9-Nitro-camptothecin (9-NC) is a new oral topoisomerase inhibitor with a good safety profile. The aims of the current study were to evaluate the activity and safety of 9-NC ...

journal_title：Cancer

authors： Quintas-Cardama A,Kantarjian H,O'Brien S,Jabbour E,Giles F,Ravandi F,Faderl S,Pierce S,Shan J,Verstovsek S,Cortes J

更新日期：2006-10-01 00:00:00

abstract：BACKGROUND:Gastric carcinoma is one of the most common malignancies worldwide, with an overall survival of about 10%. Improvement in therapy awaits better understanding of the biologic behavior of this tumor. Establishment of cell lines permits detailed analysis of the biology of gastric cancer. The authors report on t...

journal_title：Cancer

authors： Altorki N,Schwartz GK,Blundell M,Davis BM,Kelsen DP,Albino AP

更新日期：1993-08-01 00:00:00

abstract：:Retinoblastoma should not be considered as the exceptional childhood cancer that shows dominant inheritance, but rather as the typical childhood cancer that embraces a prezygotic and postzygotic subgroup. Postzygotic cases are conceived as involving mutation as a first step too, but with the mutation in somatic rather...

journal_title：Cancer

authors： Knudson AG Jr

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:The first step of colorectal carcinoma spread depends on the ability of the tumor cells to degrade and invade the extracellular matrix (ECM). The objectives of the current study were to evaluate the serum pattern of laminin, C-terminal peptide of Type I (PIP), and N-terminal peptide of Type III (PIIIP) proco...

journal_title：Cancer

authors： Plebani M,Basso D,Roveroni G,De Paoli M,Galeotti F,Corsini A

更新日期：1997-04-01 00:00:00

abstract：:A parotid tumor having sebaceous differentiation and a particular histologic picture previously undescribed is reported. The tumor showed features of an adenolymphoma but almost completely lacked a lymphoid component. Sebaceous differentiation was seen in the epithelium of many cysts. Additionally, groups of oxyphilic...

journal_title：Cancer

authors： Cameron WR,Stenram U

更新日期：1979-04-01 00:00:00

abstract：:From 1954 through 1982, 57 patients with invasive, distal rectal cancer had a full-thickness local excision with curative intent. Prognostic criteria and need for further treatment were based on the histopathologic results of the operative specimen. The overall 5-year survival rate was 83.4%. The rectal cancer-specifi...

journal_title：Cancer

authors： DeCosse JJ,Wong RJ,Quan SH,Friedman NB,Sternberg SS

更新日期：1989-01-15 00:00:00

abstract：BACKGROUND:Compared with free drug, sterically stabilized liposomal drug has prolonged circulation time and, thereby, higher tumor selectivity and antitumor activity. The stability in plasma is an important consideration in the formulation of clinically useful liposomal drug. A Phase I study of a stable liposomal doxor...

journal_title：Cancer

authors： Hong RL,Tseng YL

更新日期：2001-05-01 00:00:00

abstract：:Findings from 1665 women with primary breast cancer, treated at 34 NSABP institutions in Canada and the United States, have failed to demonstrate that patients with medial-central tumors had a greater probability of developing distant metastases or dying than did those with lateral tumors despite the greater incidence...

journal_title：Cancer

authors： Fisher B,Wolmark N,Redmond C,Deutsch M,Fisher ER

更新日期：1981-10-15 00:00:00

abstract：:If women examine their breasts thoroughly and regularly they may promptly recognize abnormal tissue changes. The level of skill and motivation required for effective breast self-examination (BSE), however, is very high. In a prospective study of 304 patients with newly diagnosed breast cancer, 165 (54%) claimed to pra...

journal_title：Cancer

authors： Philip J,Harris WG,Flaherty C,Joslin CA

更新日期：1986-08-15 00:00:00

abstract：BACKGROUND:Several studies have recently reported on the importance of quality of life (QOL) in predicting the survival of patients with lung carcinoma. To confirm these reports, the relationship between survival and QOL, as measured by the European Organization for Research and Treatment of Cancer (EORTC) Quality of L...

journal_title：Cancer

authors： Herndon JE 2nd,Fleishman S,Kornblith AB,Kosty M,Green MR,Holland J

更新日期：1999-01-15 00:00:00

abstract：:To determine whether the referral of lung cancer patients to university cancer centers was related to nonclinical factors, the medical charts were reviewed for almost all lung cancer patients diagnosed during the period of 1973-1976 in New Hampshire and Vermont. Greater distance from a cancer center, lower functional ...

journal_title：Cancer

authors： Greenberg ER,Dain B,Freeman D,Yates J,Korson R

更新日期：1988-10-15 00:00:00

abstract：:The ganglioside composition of neuroblastoma samples from 53 patients was determined. Tumor sites included the adrenals (15), and the thoracic (20), abdominal (15), and pelvic (3) areas. Age of the patients at the time of surgery ranged from 1 day to over 10 years and the Stage of the tumors from A to D. Differences i...

journal_title：Cancer

authors： Schengrund CL,Repman MA,Shochat SJ

更新日期：1985-12-01 00:00:00

abstract：:Long-term survival of 1986 consecutive patients with infiltrating duct carcinoma of the breast treated at the National Cancer Institute of Milano (Italy) in two periods of time (1971 to 1972 and 1977 to 1978) was comparatively evaluated to verify if the evolving concepts in the management of breast cancer had an impac...

journal_title：Cancer

authors： Cascinelli N,Greco M,Morabito A,Bufalino R,Testori A,Baldini MT,Andreola S,Leo E,Galluzzo D,Rilke F

更新日期：1991-07-15 00:00:00

abstract：BACKGROUND:Various methods of detecting cancer with fluorescence have been developed. One type of fluorescence is based on the tumor-localizing properties of certain dyes. However, the phototoxicity of most known tumor-localizing dyes hinders the safe use of such diagnostic methods. The authors have developed a fluores...

journal_title：Cancer

authors： Lazarev VV,Roth RA,Kazakevich Y,Hang J

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:The effect of p53 protein expression and MIB-1 proliferative activity on survival and chemotherapeutic response in patients with lymph node (LN)-positive transitional cell carcinoma (TCC) of the urinary bladder remains unclear. The objective of this study was to assess the ability of these markers to predict...

journal_title：Cancer

authors： Frank I,Cheville JC,Blute ML,Lohse CM,Karnes RJ,Weaver AL,Sebo TJ,Nehra A,Zincke H

更新日期：2004-10-15 00:00:00