Immune deficiency in family members of patients with Hodgkin's disease.

abstract：BACKGROUND:Radiofrequency (RF) ablation is an increasingly applied technique. Promising results of hepatic RF ablation raised expectations of its capabilities for treatment of primary and secondary lung tumors. Because of different thermal and electrical properties of lung tissue, compared with liver tissue, a simple a...

journal_title：Cancer

authors： Clasen S,Krober SM,Kosan B,Aebert H,Fend F,Bomches A,Claussen CD,Pereira PL

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:English and Chinese are two of the most widely used primary languages in the world. Patients in many cancer centers have a variety of ethnic backgrounds and primary languages. The comparability of version 4 of the English and Chinese versions of the Functional Assessment of Cancer Therapy-General (FACT-G) an...

journal_title：Cancer

authors： Cheung YB,Thumboo J,Goh C,Khoo KS,Che W,Wee J

更新日期：2004-12-15 00:00:00

abstract：:Five hundred forty three adult patients with acute leukemia were entered on the study designed to: (1) test efficacy of vincristine and prednisone used as primary drug therapy in patients with good prognosis as judged by a circulating blast cell count less than 30,000 cm2; (2) investigate the use of either simultaneou...

journal_title：Cancer

authors： McCredie KB,Gehan EA,Freireich EJ,Hewlett JS,Coltman CA Jr,Hussein KK,Balcerzak SP,Chen TT

更新日期：1983-09-15 00:00:00

abstract：BACKGROUND:Neuroblastoma is the most common malignancy among infants, but risk factors remain poorly understood. Because most patients present in the first few years of life, it has been hypothesized that prenatal and perinatal exposures may contribute to the pathogenesis of neuroblastoma. METHODS:A population-based c...

journal_title：Cancer

authors： Chow EJ,Friedman DL,Mueller BA

更新日期：2007-03-01 00:00:00

abstract：:Adenoid cystic carcinoma (ACC) of the breast is a rare histologic type of breast cancer associated with a good prognosis. A woman who earlier had a pulmonary metastasis surgically resected 6 years postmastectomy developed clinically symptomatic bleeding from a renal metastasis 12 years postmastectomy. An atypical angi...

journal_title：Cancer

authors： Herzberg AJ,Bossen EH,Walther PJ

更新日期：1991-09-01 00:00:00

abstract：:Neuroblastoma is the most common neoplasm in children less than 1 year of age and has one of the earliest incidence peaks of all childhood cancers. Using birth registration data, a matched case-control study was undertaken to investigate potential prenatal and perinatal risk factors. Ninety-seven neuroblastoma patient...

journal_title：Cancer

authors： Neglia JP,Smithson WA,Gunderson P,King FL,Singher LJ,Robison LL

更新日期：1988-06-01 00:00:00

abstract：:Angioendotheliomatosis is a rare intravascular neoplastic process which has been presumed to be of endothelial origin. A 62-year-old woman had manifestations of this disorder which were initially localized to the nasal region, followed by fatal systemic dissemination. Electron microscopic examination of the neoplastic...

journal_title：Cancer

authors： Wick MR,Banks PM,McDonald TJ

更新日期：1981-12-01 00:00:00

abstract：:A 1.95-kg fetus delivered at 33 weeks' gestational age survived less than 1 hour. Physical examination and autopsy disclosed an enormous, protuberant primary malignant melanoma of the skin, enveloping most of the back. A rim of surrounding hyperpigmented skin proved to be a giant congenital melanocytic nevus (GCMN), f...

journal_title：Cancer

authors： Schneiderman H,Wu AY,Campbell WA,Forouhar F,Yamase H,Greenstein R,Grant-Kels JM

更新日期：1987-09-15 00:00:00

abstract：:The geographic and demographic data obtained during the Third National Cancer Survey have provided a perspective on etiologic factors and incidence trends for cancers of low frequency. The incidence of cancer of the lip, oral cavity and skin from this survey was compared to similar studies in 1947 and intra-regional p...

journal_title：Cancer

authors： Szpak CA,Stone MJ,Frenkel EP

更新日期：1977-07-01 00:00:00

abstract：BACKGROUND:Quality of life (QOL) issues in patients with head and neck carcinoma are of importance beyond the incidence of these tumors because of the impact of the disease and its treatment on external appearance and function of the upper aerodigestive tract. Nasopharyngeal carcinoma (NPC) patients comprise a unique s...

journal_title：Cancer

authors： Talmi YP,Horowitz Z,Bedrin L,Wolf M,Chaushu G,Kronenberg J,Pfeffer MR

更新日期：2002-02-15 00:00:00

abstract：:Myelofibrosis occurs in various hematologic neoplasias, including myelodysplastic syndrome (MDS), with a relatively low incidence. To gain insight into the clinical and cytogenetic implications of MDS patients in whom myelofibrosis develops, statistical analysis was done on 82 primary MDS patients with successful cyto...

journal_title：Cancer

authors： Ohyashiki K,Sasao I,Ohyashiki JH,Murakami T,Iwabuchi A,Tauchi T,Saito M,Nakazawa S,Serizawa H,Ebihara Y

更新日期：1991-07-01 00:00:00

abstract：:Amputation is often a component in the treatment of bone tumors such as osteogenic sarcoma, which is most prevalent in the adolescent age group. Adaptation to cancer and loss of a limb requires a significant multidimensional effort. To examine the role of social support systems, 27 adolescents who had undergone amputa...

journal_title：Cancer

authors： Tebbi CK,Stern M,Boyle M,Mettlin CJ,Mindell ER

更新日期：1985-08-15 00:00:00

abstract：:Gonadal dosimetry and spermatogenic activity was monitored in patients given radiation therapy (RT) after unilateral orchiectomy for seminoma. The RT given was, with minor variations, 3200 rad in 16 fractions in four weeks to the para-aortic and ipsilateral pelvic inguinal lymphatics in order to include the orchiectom...

journal_title：Cancer

authors： Hahn EW,Feingold SM,Simpson L,Batata M

更新日期：1982-07-15 00:00:00

abstract：BACKGROUND:In many areas of health care, whether patients receive specific medical interventions often is influenced heavily by the local availability of resources for delivering those services. However, relations between resource availability and utilization are relatively unexplored in cancer care, including perioper...

journal_title：Cancer

authors： Wong SL,Wei Y,Birkmeyer JD

更新日期：2007-02-15 00:00:00

abstract：BACKGROUND:Historically, estrogen receptor (ER) determinations have been made by the ligand-binding assay of tumor homogenates, primarily by the dextran-coated charcoal method (DCC). Immunocytochemical assays (ICA) for ER are more recent and have been executed mostly on frozen sections with the monoclonal antibody H222...

journal_title：Cancer

authors： Pertschuk LP,Feldman JG,Kim YD,Braithwaite L,Schneider F,Braverman AS,Axiotis C

更新日期：1996-06-15 00:00:00

abstract：:Thyroglobulin messenger RNA (mRNA) was located and quantified in tissue sections of differentiated human thyroid cancers by in situ hybridization using cloned complementary DNA probes. The cells of the well-differentiated follicular and papillary forms contained similar levels of thyroglobulin mRNA, corresponding to a...

journal_title：Cancer

authors： Bergé-Lefranc JL,Cartouzou G,De Micco C,Fragu P,Lissitzky S

更新日期：1985-07-15 00:00:00

abstract：:Distant nontraumatic clostridial myonecrosis in association with malignancy is an uncommon disorder, with only 14 well-documented cases previously reported in the English literature. Clostridium perfringens and C. septicum are the most common organisms, usually gaining access to the circulation through an ulcerated le...

journal_title：Cancer

authors： Kaiser CW,Milgrom ML,Lynch JA

更新日期：1986-02-15 00:00:00

abstract：BACKGROUND:A survey of the distribution of human papillomavirus (HPV) types across the spectrum of cervical cytologic categories defined by the Bethesda 2001 guidelines was conducted with the objective of examining how HPV detection by polymerase chain reaction (PCR) analysis may benefit the management of patients who ...

journal_title：Cancer

authors： Evans MF,Adamson CS,Papillo JL,St John TL,Leiman G,Cooper K

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Primary malignant splenic neoplasms are rare tumors. Apart from involvement of the spleen by malignant lymphoma, hemangiosarcoma is the most common form of primary malignant neoplasm in the spleen. The diagnosis often is made at autopsy or after spontaneous splenic rupture. The prognosis is usually poor, and...

journal_title：Cancer

authors： Søndenaa K,Heikkilä R,Nysted A,Søreide JA,Odegaard H,Pollard ML,Holter J

更新日期：1993-01-01 00:00:00

abstract：BACKGROUND:The authors evaluated the effects of taxol, a microtubular inhibitor, as a possible radiation sensitizer on the human leukemic cell line (HL-60). Taxol acts as a mitotic inhibitor, blocking cells in the G2M-phase of the cell cycle. The differential radiation sensitivity of cells in various phases of the cell...

journal_title：Cancer

authors： Choy H,Rodriguez FF,Koester S,Hilsenbeck S,Von Hoff DD

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:RAS/RAF/mitogen-activated protein kinase activation is common in myeloid malignancies. Trametinib, a mitogen-activated protein kinase kinase 1 (MEK1)/MEK2 inhibitor with activity against multiple myeloid cell lines at low nanomolar concentrations, was evaluated for safety and clinical activity in patients wi...

journal_title：Cancer

authors： Borthakur G,Popplewell L,Boyiadzis M,Foran J,Platzbecker U,Vey N,Walter RB,Olin R,Raza A,Giagounidis A,Al-Kali A,Jabbour E,Kadia T,Garcia-Manero G,Bauman JW,Wu Y,Liu Y,Schramek D,Cox DS,Wissel P,Kantarjian H

更新日期：2016-06-15 00:00:00

abstract：BACKGROUND:Partial splenic embolization (PSE) has been used to improve hematologic parameters related to hypersplenism. The purpose of this study was to review our institutional experience with PSE for cancer patients with thrombocytopenia because of splenic sequestration precluding the administration of systemic thera...

journal_title：Cancer

authors： Kauffman CR,Mahvash A,Kopetz S,Wolff RA,Ensor J,Wallace MJ

更新日期：2008-05-15 00:00:00

abstract：:Sixty-four evaluable patients with hepatic metastases from colorectal carcinoma, who did not have evidence of extrahepatic disease, were treated with intrahepatic (IH) mitomycin C (M) after disease progression or intolerance to treatment with IH fluorodeoxyuridine (FUDR). Eleven patients (17%) had a partial response (...

journal_title：Cancer

authors： Schneider A,Kemeny N,Chapman D,Niedzwiecki D,Oderman P

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:p53 gene mutation and p53 protein accumulation are common in human cancer. However, their clinical significance is controversial and p53 accumulation may not correlate with gene mutation. The current study investigates the occurrence of p53 alterations in esophageal carcinoma, the correlation between the ana...

journal_title：Cancer

authors： Coggi G,Bosari S,Roncalli M,Graziani D,Bossi P,Viale G,Buffa R,Ferrero S,Piazza M,Blandamura S,Segalin A,Bonavina L,Peracchia A

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:Patients with gastric cancer have a poor prognosis and can be cured by surgery only if the cancer is detected in an early stage. Extended surgery, down staging with chemotherapy before operation, and new postoperative treatments are recent approaches to increase survival rates. Categorizing patients' prognos...

journal_title：Cancer

authors： Ganesh S,Sier CF,Heerding MM,van Krieken JH,Griffioen G,Welvaart K,van de Velde CJ,Verheijen JH,Lamers CB,Verspaget HW

更新日期：1996-03-15 00:00:00

abstract：BACKGROUND:Transforming growth factor beta (TGFbeta) is important in colorectal cancer (CRC) progression. Bone morphogenetic proteins (BMPs), a subgroup within the TGFbeta superfamily, recently also have been implicated in CRC, but their precise role in CRC has yet to be investigated. METHODS:The authors used a tissue...

journal_title：Cancer

authors： Kodach LL,Bleuming SA,Musler AR,Peppelenbosch MP,Hommes DW,van den Brink GR,van Noesel CJ,Offerhaus GJ,Hardwick JC

更新日期：2008-01-15 00:00:00

abstract：:The disposition of many drugs in obesity is altered, although little is known of the effect of obesity on the pharmacokinetics of anti-cancer drugs. In this report the authors describe the pharmacokinetics of high-dose methotrexate in an obese woman (184% ideal body weight) with osteosarcoma. For this patient, both th...

journal_title：Cancer

authors： Fleming RA,Eldridge RM,Johnson CE,Stewart CF

更新日期：1991-09-15 00:00:00

abstract：:An Epstein-Barr virus (EBV)-negative lymphoma line (JBL) was established in vitro from pleural effusion of an EBV-seropositive 29-year-old Japanese female with Burkitt's lymphoma. JBL cells as well as her original lymphoma cells bore monoclonal surface IgM with lambda light chains. The JBL line grew in single cell sus...

journal_title：Cancer

authors： Miyoshi I,Hiraki S,Kubonishi I,Matsuda Y,Kishimoto H,Nakayama T,Tanaka T,Masuji H,Kimura I

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:The Ets-1 transcription factor has been proposed to play an important role in the invasive process of tumor cells through the induction of urokinase-type plasminogen activator (u-PA). METHODS:Because meningiomas are potentially invasive tumors, irrespective of their malignancy grades, the authors immunohist...

journal_title：Cancer

authors： Kitange G,Tsunoda K,Anda T,Nakamura S,Yasunaga A,Naito S,Shibata S

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Previous studies in the literature have suggested that radiolabeled F(ab')2 fragments might be superior to whole immunoglobulin G (IgG) for imaging and therapy of cancer because of their greater penetration in tumors. To test this hypothesis, the authors compared tumor and normal tissue uptake along with pla...

journal_title：Cancer

authors： Murray JL,Rosenblum MG,Zhang HZ,Podoloff DA,Kasi LP,Curley SA,Chan JC,Roh M,Hohn DC,Brewer H

更新日期：1994-02-01 00:00:00