Abstract:
:A 1.95-kg fetus delivered at 33 weeks' gestational age survived less than 1 hour. Physical examination and autopsy disclosed an enormous, protuberant primary malignant melanoma of the skin, enveloping most of the back. A rim of surrounding hyperpigmented skin proved to be a giant congenital melanocytic nevus (GCMN), from which the cutaneous melanoma had arisen. Autopsy demonstrated metastatic melanoma in the lungs, liver, spinal cord, leptomeninges, and placenta. Radiography and dissection confirmed that the melanoma had minimal connection to spinal or neural structures. The mother was clinically free of tumor 8 months after she was delivered of the infant. Pathologic, radiographic, histologic, immunohistochemical, and ultrastructural investigations of this unique case are presented.
journal_name
Cancerjournal_title
Cancerauthors
Schneiderman H,Wu AY,Campbell WA,Forouhar F,Yamase H,Greenstein R,Grant-Kels JMdoi
10.1002/1097-0142(19870915)60:6<1371::aid-cncr2820subject
Has Abstractpub_date
1987-09-15 00:00:00pages
1371-7issue
6eissn
0008-543Xissn
1097-0142journal_volume
60pub_type
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