Neonatal benign sacrococcygeal teratoma may recur in adulthood and give rise to malignancy.

abstract：:Plasma levels of cyclic AMP and cyclic GMP were determined in 35 guinea pigs for up to 9 days following subcutaneous passage of L2C leukemia cells. Twenty guinea pigs into which normal syngeneic guinea pig thymocytes were passaged served as controls. Cyclic AMP levels in plasma showed little change and were only eleva...

journal_title：Cancer

authors： Wood PJ,Pao G,Cooper A

更新日期：1984-01-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinases (MMP) are a gene family of zinc enzymes capable of degrading almost all of the extracellular matrix macromolecules in vivo. Their enzymic activities are believed to be responsible for tumor invasion and metastasis. METHODS:In this study, using peroxidase-antiperoxidase method, mono...

journal_title：Cancer

authors： Shima I,Sasaguri Y,Kusukawa J,Yamana H,Fujita H,Kakegawa T,Morimatsu M

更新日期：1992-12-15 00:00:00

abstract：BACKGROUND:Patients with multiple myeloma (MM) have increased bone marrow angiogenesis, a low plasma cell labeling index, and multidrug resistance (the primary cause of chemotherapy failure). MM patients receiving the vincristine, doxorubicin, and dexamethasone (VAD) regimen develop resistance and cardiac and steroid t...

journal_title：Cancer

authors： Hussein MA,Wood L,Hsi E,Srkalovic G,Karam M,Elson P,Bukowski RM

更新日期：2002-11-15 00:00:00

abstract：:Interleukin (IL)-2 therapy leads to respiratory dysfunction due to increased vascular permeability. This study examines the role of the chemoattractant, immunomodulator, and permeability-promoting agent leukotriene (LT) B4 in this setting. Sheep with chronic lung lymph fistulae were given IL-2, 10(5) U/kg as an IV bol...

journal_title：Cancer

authors： Klausner JM,Goldman G,Skornick Y,Valeri R,Inbar M,Shepro D,Hechtman HB

更新日期：1990-12-01 00:00:00

abstract：:K-ras gene mutation in colorectal tumors from patients with familial polyposis coli were investigated using oligonucleotide probes specific for a mutation at codon 12, 13, or 61 of the K-ras gene. The authors examined 22 colorectal carcinomas and 51 colorectal adenomas from 41 familial polyposis coli patients and obse...

journal_title：Cancer

authors： Sasaki M,Sugio K,Sasazuki T

更新日期：1990-06-01 00:00:00

abstract：:High-dose multiagent chemotherapy followed by autologous marrow rescue was used in the treatment of 13 patients with Stage III or IV childhood tumors. Encouraging results are being obtained in abdominal lymphoma (1/3 complete remissions (CR); rhabdomyosarcoma (2/4 CR); and retinoblastoma (1/2 CR). In neuroblastoma, th...

journal_title：Cancer

authors： Ekert H,Ellis WM,Waters KD,Tauro GP

更新日期：1982-02-01 00:00:00

abstract：:All patients with a diagnosis of cutaneous malignant melanoma (CMM) in Western Australia from 1980 to 1981 were observed for up to 6 years to determine vital status and to detect the development of local recurrences of the primary lesion. Approximately 35% of all patients had their tumors excised with surgical margins...

journal_title：Cancer

authors： Heenan PJ,English DR,Holman CD,Armstrong BK

更新日期：1992-01-15 00:00:00

abstract：:Three patients had supratentorial malignant brain tumors 7 to 9 years after prophylactic central nervous system (CNS) treatment for acute lymphocytic leukemia or malignant T-cell lymphoma. Therapy was administered at the age of 3 to 8 years and included cranial irradiation (total dose, 1800 to 2400 cGy) and intratheca...

journal_title：Cancer

authors： Brüstle O,Ohgaki H,Schmitt HP,Walter GF,Ostertag H,Kleihues P

更新日期：1992-05-01 00:00:00

abstract：:The results of nine US multicenter, sequential crossover, dose titration studies of controlled-release oral morphine (MS Contin 30 mg tablets [MSC], Purdue Frederick, Norwalk, CT) are reviewed in Part I. The studies demonstrated the prolonged analgesic efficacy of the preparation in the treatment of patients with mode...

journal_title：Cancer

authors： Kaiko RF,Grandy RP,Oshlack B,Pav J,Horodniak J,Thomas G,Ingber E,Goldenheim PD

更新日期：1989-06-01 00:00:00

abstract：:Epithelioid sarcoma is an uncommon tumor characterized by its appearance in the distal extremities (especially the forearm, wrist, and ankle), the tendency to recur locally, and high probability of spread to regional lymph nodes. Most patients have been treated surgically, and the potential role of radiation therapy a...

journal_title：Cancer

authors： Shimm DS,Suit HD

更新日期：1983-09-15 00:00:00

abstract：BACKGROUND:Early-phase trials in patients with recurrent neuroblastoma historically used an objective "response" of measureable disease (Response Evaluation Criteria In Solid Tumors [RECIST], without bone/bone marrow assessment) to select agents for further study. Historical cohorts may be small and potentially biased;...

journal_title：Cancer

authors： London WB,Bagatell R,Weigel BJ,Fox E,Guo D,Van Ryn C,Naranjo A,Park JR

更新日期：2017-12-15 00:00:00

abstract：:The validity of current staging systems for malignant melanoma was analyzed in a prospective study on 220 patients with extremity melanoma. Patients were followed 2 to 9 years after a wide excision of the primary, regional cytostatic perfusion and dissection of regional lymph nodes. The "original three-stage" system y...

journal_title：Cancer

authors： Ghussen F,Krüger I,Groth W

更新日期：1990-07-15 00:00:00

abstract：:Karyotypes from seven patients with thyroid lymphoma were studied before treatment. When the cytogenetic results were correlated with the clinical data, it became evident that there are two distinct groups of patients with thyroid lymphoma. In a group of patients with solely numerical abnormalities the disease is asso...

journal_title：Cancer

authors： Taniwaki M,Nishida K,Misawa S,Takino T,Abe T,Aozasa K,Katagiri S,Yonezawa T,Matsuzuka F,Kuma K

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:After the introduction of a mammography screening program, the incidence of late-stage breast cancer is expected to decrease. The objective of the current study was to evaluate variations in the total incidence of breast cancer and in the incidence of breast cancers with a pathologic tumor (pT) classificatio...

journal_title：Cancer

authors： Foca F,Mancini S,Bucchi L,Puliti D,Zappa M,Naldoni C,Falcini F,Gambino ML,Piffer S,Sanoja Gonzalez ME,Stracci F,Zorzi M,Paci E,IMPACT Working Group.

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Both genetic and epigenetic changes in nonsmall cell lung cancer (NSCLC) are known to be a common event. METHODS:Mutations in the epidermal growth factor receptor gene (EGFR), HER-2, and KRAS and the methylation profile of 9 genes for NSCLC were analyzed and correlated with clinical and histologic data. RE...

journal_title：Cancer

authors： Suzuki M,Shigematsu H,Iizasa T,Hiroshima K,Nakatani Y,Minna JD,Gazdar AF,Fujisawa T

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:Age-related disparities in colon cancer treatment exist, with older patients being less likely to receive recommended therapy. However, to the authors' knowledge, few studies to date have focused on receipt of surgery. The objective of the current study was to describe patterns of surgery in patients aged ≥ ...

journal_title：Cancer

authors： Neuman HB,O'Connor ES,Weiss J,Loconte NK,Greenblatt DY,Greenberg CC,Smith MA

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Sunitinib malate is an orally bioavailable tyrosine kinase inhibitor that is active against many tyrosine kinase receptors involving crucial pathways in both healthy tissues and malignant tissues. Because its use in clinical practice is quite recent, many of its possible side effects remain unknown. In this ...

journal_title：Cancer

authors： Baldazzi V,Tassi R,Lapini A,Lunghi A,Garofoli E,Caruso S,Carini M,Mazzanti R

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess whether coregistered whole brain (WB) magnetic resonance imaging-positron emission tomography (MRI-PET) would increase the number of correctly upstaged patients compared with WB PET-computed tomography (PET-CT) plus dedicated brain MRI in patients with nonsmall cell ...

journal_title：Cancer

authors： Yi CA,Lee KS,Lee HY,Kim S,Kwon OJ,Kim H,Choi JY,Kim BT,Hwang HS,Shim YM

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:The local control rates of T1 and T2 supraglottic carcinoma treated with radiation alone were reported as 71% to 92% and 59% to 83%, respectively. The factors that affect the local control rate for early supraglottic carcinoma were investigated. METHODS:From 1967 through 1985, 100 cases with early supraglot...

journal_title：Cancer

authors： Inoue T,Matayoshi Y,Inoue T,Ikeda H,Teshima T,Murayama S

更新日期：1993-07-01 00:00:00

abstract：:Pleural fluid and serum protein electrophoresis and quantitative immunoglobulin measurements were carried out in patients with pleural effusions. The mean pleural fluid/serum ratios of IgA, IgG, and IgM were elevated in patients with malignant pleural effusions compared with patients with nonmalignant pleural effusion...

journal_title：Cancer

authors： Desai SD,Sackett DL

更新日期：1983-12-01 00:00:00

abstract：BACKGROUND:Increased soluble human epidermal growth factor receptor 2 (sHER2) is an indicator of a poor prognosis in HER2-positive metastatic breast cancer. In this study, the authors evaluated levels of sHER2 during treatment and at the time of disease recurrence in the adjuvant North Central Cancer Treatment Group N9...

journal_title：Cancer

authors： Moreno-Aspitia A,Hillman DW,Dyar SH,Tenner KS,Gralow J,Kaufman PA,Davidson NE,Lafky JM,Reinholz MM,Lingle WL,Kutteh LA,Carney WP,Dueck AC,Perez EA

更新日期：2013-08-01 00:00:00

abstract：:The diagnosis of brain metastasis from prostate carcinoma is rarely made antemortem, and has previously been reported only in patients with known extensive metastatic disease of long duration. A case of adenocarcinoma of the prostate presenting as a brain metastasis is described. Current concepts of metastatic spread ...

journal_title：Cancer

authors： Baumann MA,Holoye PY,Choi H

更新日期：1984-10-15 00:00:00

abstract：BACKGROUND:The objective of this study was to compare findings after a cytologic report of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion (LSIL-H) with findings after a report of low-grade squamous intraepithelial lesion (LSIL). METHODS:A review of patient records ...

journal_title：Cancer

authors： Al-Nourhji O,Beckmann MJ,Markwell SJ,Massad LS

更新日期：2008-12-25 00:00:00

abstract：:In the past few years, the role of membrane-bound transport genes in human disease has been increasingly recognized and understood. Of these genes, the p170 membrane glycoprotein may function as an outward transport pump for many cancer chemotherapeutic drugs associated with the multidrug resistance phenotype. This ar...

journal_title：Cancer

authors： Leyland-Jones B,Dalton W,Fisher GA,Sikic BI

更新日期：1993-12-01 00:00:00

abstract：:A 17-year-old girl was operated for a solitary well-circumscribed pulmonary parenchymal tumor and reoperated ten times for multiple recurrent similar pulmonary tumors during 24 years. Histologic examination revealed the so-called intravascular bronchioloalveolar tumor (IVBAT) in all instances. The patient died from pn...

journal_title：Cancer

authors： Miettinen M,Collan Y,Halttunen P,Maamies T,Vilkko P

更新日期：1987-11-15 00:00:00

abstract：BACKGROUND:Many patients with hepatocellular carcinoma are positive for hepatitis B surface antigen (HBsAg) or antibodies to hepatitis C virus (anti-HCV). Recently, transfusion-transmitted virus (TTV) DNA was identified in the serum of patients with non-B, non-C posttransfusion hepatitis. In this study, the prevalence ...

journal_title：Cancer

authors： Nakagawa N,Ikoma J,Ishihara T,Yasui N,Fujita N,Iwasa M,Kaito M,Watanabe S,Adachi Y

更新日期：1999-10-15 00:00:00

abstract：:Between September 21, 1973 and May 9, 1975, 36 patients with metastatic cervical adenopathy from cancers primarily arising in the pharynx or oral cavity, including six with bilateral cervical involvement, received fast neutron teletherapy at the University of Washington. At the conclusion of treatment, the masses were...

journal_title：Cancer

authors： Berry HC,Parker RG,Gerdes AJ

更新日期：1976-06-01 00:00:00

abstract：:The American Joint Committee on Cancer proposes the following criteria for evaluating putative prognostic factors: they must be (1) significant, (2) independent, and (3) clinically important. Furthermore, we suggest the criteria for selecting a prognostic system that includes TNM and new prognostic factors. These crit...

journal_title：Cancer

authors： Burke HB,Henson DE

更新日期：1993-11-15 00:00:00

abstract：:Endoscopic neodymium yttrium aluminium garnet (Nd YAG) laser therapy, is a new and simple method for the palliative treatment of inoperable colorectal cancer. To date the authors have treated 70 patients and the value of this method was assessed prospectively in 14 patients. Quality of life was measured before, during...

journal_title：Cancer

authors： McGowan I,Barr H,Krasner N

更新日期：1989-03-01 00:00:00

abstract：:A case of basosquamous or so-called transitional cloacogenic carcinoma of the sigmoid colon, which arose above the pelvic brim at the peritoneal reflection, is reported. We were not able to find a report of this histologic type of tumor arising this far from the pectinate line of the anus, which is the most common pri...

journal_title：Cancer

authors： Strate RW,Richardson JD,Bannayan GA

更新日期：1977-09-01 00:00:00