Pathology correlates of a Papanicolaou diagnosis of low-grade squamous intraepithelial lesion, cannot exclude high-grade squamous intraepithelial lesion.

abstract：BACKGROUND:Tyrosine kinase inhibitors (TKIs) of the epidermal growth factor receptor (EGFR) have activity in solid tumors. The authors evaluated an oral EGFR TKI, erlotinib, in patients with previously treated esophageal cancer. METHODS:Thirty patients with measurable, metastatic cancer of the esophageal and gastroeso...

journal_title：Cancer

authors： Ilson DH,Kelsen D,Shah M,Schwartz G,Levine DA,Boyd J,Capanu M,Miron B,Klimstra D

更新日期：2011-04-01 00:00:00

abstract：:Nine patients from 34 to 74 years of age (median, 67 years of age) with uterine papillary serous carcinoma (UPSC) were treated with whole-abdominal radiation therapy (WART) on an adjuvant basis after cytoreductive surgery. All patients were treated with megavoltage photons to an abdominopelvic field to a median dose o...

journal_title：Cancer

authors： Frank AH,Tseng PC,Haffty BG,Papadopoulos DP,Kacinski BM,Dowling SW,Carcangiu ML,Kohorn EI,Chambers JT,Chambers SK

更新日期：1991-10-01 00:00:00

abstract：:Skin cancers originating in areas of chronic injury (Marjolin's ulcers) are thought to behave in a more aggressive fashion than those due to other causes. The initial surgical treatment, especially the management of the regional lymph nodes, remains controversial. This review of 37 patients with Marjolin's ulcer evalu...

journal_title：Cancer

authors： Barr LH,Menard JW

更新日期：1983-07-01 00:00:00

abstract：:Two female patients with desmoid tumors (aggressive fibromatosis) showed tumor regression after endocrine therapy. In one patient, tumor response to tamoxifen has been maintained over several years of treatment. In the second patient, who had inoperable mesenteric fibromatosis, the tumor progressed on tamoxifen but re...

journal_title：Cancer

authors： Wilcken N,Tattersall MH

更新日期：1991-09-15 00:00:00

abstract：BACKGROUND:In many areas of health care, whether patients receive specific medical interventions often is influenced heavily by the local availability of resources for delivering those services. However, relations between resource availability and utilization are relatively unexplored in cancer care, including perioper...

journal_title：Cancer

authors： Wong SL,Wei Y,Birkmeyer JD

更新日期：2007-02-15 00:00:00

abstract：:Combined teletherapy and interstitial iridium 192 implantation can control locally advanced breast cancer in a consistent fashion without causing significant morbidity. Moreover, in the absence of clinically evident distant metastases, patients who undergo this treatment can survive comfortably for long periods of tim...

journal_title：Cancer

authors： Alderman SJ

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:Prior literature has suggested synergy between immune checkpoint therapy (ICT) and radiotherapy (RT) for the treatment of brain metastases (BrM), but to the authors' knowledge the optimal timing of therapy to maximize this synergy is unclear. METHODS:A total of 199 patients with melanoma and non-small cell ...

journal_title：Cancer

authors： Qian JM,Martin AM,Martin K,Hammoudeh L,Catalano PJ,Hodi FS,Cagney DN,Haas-Kogan DA,Schoenfeld JD,Aizer AA

更新日期：2020-12-15 00:00:00

abstract：BACKGROUND:The impact of cancer on socioeconomic outcomes is attracting attention as the number of survivors of cancer in young age continues to rise. This study examines economic independence in a national cohort of survivors of cancer at a young age in Norway. METHODS:Through the linkage of several national registri...

journal_title：Cancer

authors： Gunnes MW,Lie RT,Bjørge T,Syse A,Ruud E,Wesenberg F,Moster D

更新日期：2016-12-15 00:00:00

abstract：BACKGROUND:Recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN) is associated with poor survival. Platinum-based chemotherapy is often a first-line treatment. Pemetrexed has shown single-agent activity in SCCHN and in combination with cisplatin for other tumors. This trial examined the efficacy ...

journal_title：Cancer

authors： Urba S,van Herpen CM,Sahoo TP,Shin DM,Licitra L,Mezei K,Reuter C,Hitt R,Russo F,Chang SC,Hossain AM,Frimodt-Moller B,Koustenis A,Hong RL

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:There is limited information on outcomes of prostate carcinoma treatments given to screened patient populations for whom cancer is usually detected at an earlier stage. METHODS:The authors conducted a cross-sectional evaluation of quality-of-life outcomes for men with prostate carcinoma detected in screenin...

journal_title：Cancer

authors： Smith DS,Carvalhal GF,Schneider K,Krygiel J,Yan Y,Catalona WJ

更新日期：2000-03-15 00:00:00

abstract：:Irreversible and progressive renal parenchymal damage and functional impairment occurred in the majority of patients receiving at least six courses (200 mg/m2 of BCNU and/or methyl CCNU at eight-week intervals) of nitrosoureas for therapy of malignant brain tumors. Seventeen of 18 patients who received at least six co...

journal_title：Cancer

authors： Schacht RG,Feiner HD,Gallo GR,Lieberman A,Baldwin DS

更新日期：1981-09-15 00:00:00

abstract：BACKGROUND:Constitutional or somatic mosaic epimutations are increasingly recognized as a mechanism of gene dysregulation resulting in cancer susceptibility. Beckwith-Wiedemann syndrome is the cancer predisposition syndrome most commonly associated with epimutation and is extremely variable in its phenotypic presentati...

journal_title：Cancer

authors： Fiala EM,Ortiz MV,Kennedy JA,Glodzik D,Fleischut MH,Duffy KA,Hathaway ER,Heaton T,Gerstle JT,Steinherz P,Shukla N,McNeer N,Tkachuk K,Bouvier N,Cadoo K,Carlo MI,Latham A,Dubard Gault M,Joseph V,Kemel Y,Kentsis A,

更新日期：2020-07-01 00:00:00

abstract：BACKGROUND:Telomerase is commonly recognized as an effective anticancer target. The human telomerase reverse transcriptase (hTERT), the rate-limiting component of telomerase, is expressed in most malignant tumors, but it is not found in most normal somatic cells. Here, we report a real-time and noninvasive method to mo...

journal_title：Cancer

authors： Yu ST,Li C,Lü MH,Liang GP,Li N,Tang XD,Wu YY,Shi CM,Chen L,Li CZ,Cao YL,Fang DC,Yang SM

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:A survey of the distribution of human papillomavirus (HPV) types across the spectrum of cervical cytologic categories defined by the Bethesda 2001 guidelines was conducted with the objective of examining how HPV detection by polymerase chain reaction (PCR) analysis may benefit the management of patients who ...

journal_title：Cancer

authors： Evans MF,Adamson CS,Papillo JL,St John TL,Leiman G,Cooper K

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Patients with chronic lymphocytic leukemia (CLL) that transforms to Richter syndrome (RS) frequently show atypical lymphocytes in bone marrow; however, a diagnosis of RS requires confirmation of the presence of sheets of large cells in bone marrow or lymph nodes. METHODS:In this study, the authors evaluated...

journal_title：Cancer

authors： Ma Y,Mansour A,Bekele BN,Zhou X,Keating MJ,O'Brien S,Giles FJ,Albitar M

更新日期：2004-05-15 00:00:00

abstract：:Serum sialyltransferases and fucosyltransferases measured by an affinity adsorbent technique were studied in 27 exactly defined patients with malignant pulmonary diseases. Fourteen patients with benign pulmonary diseases and 56 with benign surgical diseases were used as controls. Enzyme activities were expressed as am...

journal_title：Cancer

authors： Ronquist G,Nou E

更新日期：1983-11-01 00:00:00

abstract：:Clinicians can shed new light on the genetic and environmental origins of cancer, particularly multiple primary malignancies, by asking additional questions at the bedside. Areas to explore include occupational history, personal habits, residence, and medical and family histories with emphasis on subtle clues of disor...

journal_title：Cancer

authors： Mulvihill JJ,McKeen EA

更新日期：1977-10-01 00:00:00

abstract：BACKGROUND:The value of surgical staging and treatment of the axillary lymph nodes with either surgery or radiotherapy in the initial management of patients with Stage I or II invasive breast cancer is controversial. METHODS:A review of retrospective and prospective clinical studies was performed to assess the risks o...

journal_title：Cancer

authors： Recht A,Houlihan MJ

更新日期：1995-11-01 00:00:00

abstract：:Because chronic lymphocytic leukemia is a heterogeneous disease, there are considerable efforts underway to develop increasingly accurate and precise analytics with which to estimate the probability of future events such as the need for and probability of response to therapy, progression-free survival, and survival. T...

journal_title：Cancer

authors： Montserrat E,Gale RP

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify genome-wide single nucleotide variants and mutations in African American patients with colorectal cancer (CRC). There is a need of such studies in African Americans, because they display a higher incidence of aggressive CRC tumors. METHODS:We performed whole exome s...

journal_title：Cancer

authors： Ashktorab H,Daremipouran M,Devaney J,Varma S,Rahi H,Lee E,Shokrani B,Schwartz R,Nickerson ML,Brim H

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the racial and ethnic disparities in outcomes and their association with process-of-care measures for elderly Medicare recipients with localized prostate cancer. METHODS:The Surveillance, Epidemiology, and End Results-Medicare databases for the period from 1995 to 2...

journal_title：Cancer

authors： Jayadevappa R,Chhatre S,Johnson JC,Malkowicz SB

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:In less than a century, lung cancer has progressed from a medical curiosity to the most deadly of all malignant diseases on our planet. Because cigarette smoking is responsible for the existing global lung cancer epidemic, policy initiatives have focused almost exclusively on primary prevention. There is no ...

journal_title：Cancer

authors： Strauss GM,Dominioni L

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:The relationships between psychological and behavioral variables and patient outcomes after hematopoietic stem cell transplantation (HSCT) are not known definitively but have great potential importance, since this lifesaving procedure is used increasingly to treat a variety of malignancies. The objective of ...

journal_title：Cancer

authors： Chang G,Orav EJ,McNamara T,Tong MY,Antin JH

更新日期：2004-08-15 00:00:00

abstract：:Whether malignant cells can be detected in the bowel movements induced by oral gut lavage solution administration was studied in patients with known colonic adenocarcinomas. The induced bowel movements were collected in 27 patients, nine of whom had cancer proven by anatomic pathologic examination. The cells present w...

journal_title：Cancer

authors： Gordon IL,Rypins EB,Wuerker RB,Jakowatz JJ

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Because the addition of nimotuzumab to chemoradiation in patients with locally advanced head and neck cancer improved outcomes in a phase 2 study, the authors conducted a phase 3 study to confirm these findings. METHODS:This open-label, investigator-initiated, phase 3, randomized trial was conducted from 20...

journal_title：Cancer

authors： Patil VM,Noronha V,Joshi A,Agarwal J,Ghosh-Laskar S,Budrukkar A,Murthy V,Gupta T,Mahimkar M,Juvekar S,Arya S,Mahajan A,Agarwal A,Purandare N,Rangarajan V,Balaji A,Chaudhari SV,Banavali S,Kannan S,Bhattacharjee A,D

更新日期：2019-09-15 00:00:00

abstract：BACKGROUND:Metallothioneins (MT) are endogenous metalloproteins involved in the homeostasis of essential metals and detoxification of toxic metals. Some recent experimental studies suggested tumor resistance to cisdiamminedichloroplatin may be associated with overexpression of MT in the tumor. METHODS:The presence of ...

journal_title：Cancer

authors： Chin JL,Banerjee D,Kadhim SA,Kontozoglou TE,Chauvin PJ,Cherian MG

更新日期：1993-11-15 00:00:00

abstract：:Cancer tissues from 30 patients with squamous cell carcinoma of the oral cavity were examined immunohistopathologically as to the responsiveness of the host against its own cancer cells in both biopsy and surgically resected specimens from the same patients. Subpopulations of the infiltrating lymphocytes in cancer tis...

journal_title：Cancer

authors： Hiratsuka H,Imamura M,Ishii Y,Kohama G,Kikuchi K

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Despite improvements in survival rates, cancer treatments have significant side effects that affect the quality of life of children and their families. When an ill child cannot self-report symptoms (eg, he or she is too ill), caregiver (parent) reporting becomes critical. This study evaluates the validity an...

journal_title：Cancer

authors： Reeve BB,McFatrich M,Lin L,Lucas NR,Mack JW,Jacobs SS,Withycombe JS,Baker JN,Freyer DR,Hinds PS

更新日期：2020-12-17 00:00:00

abstract：BACKGROUND:The results of an international, multicenter, randomized, double-blind, controlled study assessing the efficacy and safety of lenalidomide treatment in patients with refractory stage IV metastatic malignant melanoma are reported. METHODS:The study compared treatment with lenalidomide (25 mg/d on Days 1-21 o...

journal_title：Cancer

authors： Eisen T,Trefzer U,Hamilton A,Hersey P,Millward M,Knight RD,Jungnelius JU,Glaspy J

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Kaiser Permanente (KP) is a large health maintenance organization (HMO) operating in 14 states and caring for 8,000,000 members in hundreds of facilities staffed by thousands of physicians and support personnel. Cancer care is provided to these KP members as part of the health care package. METHODS:KP insur...

journal_title：Cancer

authors： Glass A

更新日期：1998-05-15 00:00:00