Palliative laser therapy for inoperable rectal cancer--does it work? A prospective study of quality of life.

Abstract:

:Endoscopic neodymium yttrium aluminium garnet (Nd YAG) laser therapy, is a new and simple method for the palliative treatment of inoperable colorectal cancer. To date the authors have treated 70 patients and the value of this method was assessed prospectively in 14 patients. Quality of life was measured before, during, and after treatment. The quality of life (QL) index, a physician's assessment and a linear analogue self-assessment (LASA) were used. A close correlation was found between the two assessment methods (r = 0.79). Overall there was a significant improvement from the mean pretreatment score and the best score achieved posttreatment (QL: P = 0.002; LASA: P = 0.002). Patients with diarrhea, rectal bleeding, mucus discharge, or pain secondary to tumor bulk, will benefit most from this treatment. Malignant cachexia, pain secondary to sacral plexus involvement, tumor encroachment on the anal canal and/or sphincter dysfunction resulting from tumor invasion should be viewed as relative contraindications to laser therapy. The authors conclude that in selected patients endoscopic laser therapy can provide effective palliation in patients with malignant tumors of the rectum and descending colon.

journal_name

Cancer

journal_title

Cancer

authors

McGowan I,Barr H,Krasner N

doi

10.1002/1097-0142(19890301)63:5<967::aid-cncr28206

subject

Has Abstract

pub_date

1989-03-01 00:00:00

pages

967-9

issue

5

eissn

0008-543X

issn

1097-0142

journal_volume

63

pub_type

杂志文章

相关文献

CANCER文献大全
  • Multifocal adenocarcinoma of the jejunum.

    abstract::We report on an 89-year-old female admitted with signs of intestinal obstruction in whom three independent adenocarcinomas of the proximal jejunum were found. Multiple foci of pyloric gland metaplasia, glandular hyperplasia and dysplasia, carcinoma-in-situ, and several varieties of adenocarcinoma were identified on mi...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197909)44:3<1142::aid-cncr282044

    authors: Warner TF,Peralta J

    更新日期:1979-09-01 00:00:00

  • The Reach to Recovery program.

    abstract::The diagnosis of breast cancer brings with it significant psychosocial concerns and questions. Part of providing comprehensive care for a woman with breast cancer requires the physician to be aware of the Reach To Recovery Program, which is a peer modeling program provided by the American Cancer Society. The women who...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.2820741324

    authors: Rinehart ME

    更新日期:1994-07-01 00:00:00

  • Cancer of the urinary bladder in blacks and whites. A case-control study.

    abstract::Racial differences in the risk of cancer of the urinary bladder associated with cigarette smoking and alcohol consumption were examined in a study of 1663 cases (1534 whites and 129 blacks) and 4930 controls matched 3:1 by sex, race, and age to the cases. Significant increases in cancer risk associated with cigarette ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19901215)66:12<2673::aid-cncr282

    authors: Harris RE,Chen-Backlund JY,Wynder EL

    更新日期:1990-12-15 00:00:00

  • Symptomatic mucocutaneous toxicity of hydroxyurea in Philadelphia chromosome-negative myeloproliferative neoplasms: the Mister Hyde face of a safe drug.

    abstract:BACKGROUND:The current study was conducted to evaluate severe mucocutaneous toxicity during treatment with hydroxyurea (HU) in a large cohort of patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPN). METHODS:Among 993 consecutive patients newly diagnosed with MPN at 4 centers in Rome betwee...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26194

    authors: Latagliata R,Spadea A,Cedrone M,Di Giandomenico J,De Muro M,Villivà N,Breccia M,Anaclerico B,Porrini R,Spirito F,Rago A,Avvisati G,Alimena G,Montanaro M,Andriani A,Gruppo Laziale SMPC Ph1 neg.

    更新日期:2012-01-15 00:00:00

  • Tivantinib (ARQ 197), a selective inhibitor of MET, in patients with microphthalmia transcription factor-associated tumors: results of a multicenter phase 2 trial.

    abstract:BACKGROUND:Microphthalmia transcription factor (MITF)-associated (MiT) tumors are a family of rare malignancies, including alveolar soft part sarcoma (ASPS), clear cell sarcoma (CCS), and translocation-associated renal cell carcinoma (tRCC) that have dysregulated expression of oncogenic MITF family proteins. The MET re...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.27582

    authors: Wagner AJ,Goldberg JM,Dubois SG,Choy E,Rosen L,Pappo A,Geller J,Judson I,Hogg D,Senzer N,Davis IJ,Chai F,Waghorne C,Schwartz B,Demetri GD

    更新日期:2012-12-01 00:00:00

  • Thin cutaneous malignant melanomas (< or =1.5 mm): identification of risk factors indicative of progression.

    abstract:BACKGROUND:Although thin cutaneous melanomas generally have a favorable prognosis, in some cases they may undergo progression. The current study was undertaken to identify variables that may predict a more aggressive clinical outcome in these patients. In addition to classic clinicopathologic features, the authors test...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19990301)85:5<1067::aid-cn

    authors: Massi D,Franchi A,Borgognoni L,Reali UM,Santucci M

    更新日期:1999-03-01 00:00:00

  • Nonaspirin nonsteroidal anti-inflammatory drugs and gastric cancer risk after Helicobacter pylori eradication: A territory-wide study.

    abstract:BACKGROUND:Despite Helicobacter pylori (HP) eradication, individuals can still develop gastric cancer (GC). Prior studies have demonstrated that nonaspirin nonsteroidal anti-inflammatory drugs (NA-NSAIDs) reduce the risk of GC, but this may be caused by immortal time bias and failure to adjust for HP status. The object...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.33412

    authors: Li B,Cheung KS,Wong IY,Leung WK,Law S

    更新日期:2021-01-20 00:00:00

  • Revision of the World Health Organization classification of brain tumors for childhood brain tumors.

    abstract::A classification for childhood brain tumors based upon revision of nomenclature of all brain tumors published by the World Health Organization (WHO) in 1979 is proposed. Applicability of the WHO classification scheme was tested in a combined study of the clinical and pathologic features of approximately 3300 brain tum...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19851001)56:7+<1869::aid-cncr282

    authors: Rorke LB,Gilles FH,Davis RL,Becker LE

    更新日期:1985-10-01 00:00:00

  • Latent Epstein-Barr virus infection is an unlikely event in the pathogenesis of immunoproliferative small intestinal disease.

    abstract:BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19940915)74:6<1699::aid-cncr2820

    authors: Baddoura FK,Unger ER,Mufarrij A,Nassar VH,Zaki SR

    更新日期:1994-09-15 00:00:00

  • Genome-wide association study identifies common genetic variants associated with salivary gland carcinoma and its subtypes.

    abstract:BACKGROUND:Salivary gland carcinomas (SGCs) are a rare malignancy with unknown etiology. The objective of the current study was to identify genetic variants modifying the risk of SGC and its major subtypes: adenoid cystic carcinoma and mucoepidermoid carcinoma. METHODS:The authors conducted a genome-wide association s...

    journal_title:Cancer

    pub_type: 杂志文章,收录出版

    doi:10.1002/cncr.29381

    authors: Xu L,Tang H,Chen DW,El-Naggar AK,Wei P,Sturgis EM

    更新日期:2015-07-15 00:00:00

  • Long-term surgical outcomes of temporal lobe epilepsy associated with low-grade brain tumors.

    abstract:BACKGROUND:Tumor-related temporal lobe epilepsy (TLE) has a high likelihood of medical intractability and requires surgical treatment. The aims of this study were to analyze the long-term surgical outcomes of and to present appropriate surgical strategies for tumor-related TLE. METHODS:The clinical data of 87 consecut...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.24666

    authors: Phi JH,Kim SK,Cho BK,Lee SY,Park SY,Park SJ,Lee SK,Kim KJ,Chung CK

    更新日期:2009-12-15 00:00:00

  • The prognostic significance of sialyl-Tn antigen in women treated with breast carcinoma treated with adjuvant chemotherapy.

    abstract:BACKGROUND:Sialyl-Tn (STn) represents an aberrantly glycosylated mucin epitope that is expressed in breast carcinoma and other adenocarcinomas and is an important factor in the development of novel immunotherapeutic approaches. The primary aim of the current study was to investigate the influence of STn expression on t...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/(sici)1097-0142(19971215)80:12<2240::aid-c

    authors: Kinney AY,Sahin A,Vernon SW,Frankowski RF,Annegers JF,Hortobagyi GN,Buzdar AU,Frye DK,Dhingra K

    更新日期:1997-12-15 00:00:00

  • Multifocal breast cancer documented in large-format histology sections: long-term follow-up results by molecular phenotypes.

    abstract:BACKGROUND:The prognostic significance of molecular phenotype in breast cancer is well established in the literature. Recent studies have demonstrated that subgross lesion distribution (unifocal, multifocal, and diffuse) and disease extent also carry prognostic significance in this disease. However, the correlation of ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27877

    authors: Pekar G,Hofmeyer S,Tabár L,Tarján M,Chen TH,Yen AM,Chiu SY,Hellberg D,Gere M,Tot T

    更新日期:2013-03-15 00:00:00

  • Positron emission tomography of patients with head and neck carcinoma before and after high dose irradiation.

    abstract:BACKGROUND:Positron emission tomography (PET) with labeled fluorodeoxyglucose (FDG) demonstrates increased tracer uptake in many neoplasms. This study was undertaken to define the patterns of FDG uptake in head and neck neoplasms before and after high dose irradiation. METHODS:Twenty-five patients were evaluated prosp...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19940815)74:4<1355::aid-cncr2820

    authors: Greven KM,Williams DW 3rd,Keyes JW Jr,McGuirt WF,Watson NE Jr,Randall ME,Raben M,Geisinger KR,Cappellari JO

    更新日期:1994-08-15 00:00:00

  • Testis cancer. Ichthyosis constitutes a significant risk factor.

    abstract::Testis cancer and ichthyosis are both relatively rare diseases. Hence the finding of six individuals with both these conditions in a small population with testicular cancer is highly conspicuous and indicates some kind of connection among such persons. Despite the identical clinical appearances of their ichthyoses, th...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910201)67:3<730::aid-cncr28206

    authors: Lykkesfeldt G,Bennett P,Lykkesfeldt AE,Micic S,Rørth M,Skakkebaek NE,Svenstrup B

    更新日期:1991-02-01 00:00:00

  • Early detection of malignancy in ulcerative colitis. A flow-cytometric DNA study.

    abstract::The cellular DNA content in colorectal biopsies from 51 patients with chronic ulcerative colitis has been studied with flow-cytometric technique. The DNA pattern has been related to the duration of the disease, and to histopathology. Aneuploid cell lines were found in eight patients, two of which had histopathological...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840115)53:2<291::aid-cncr28205

    authors: Hammarberg C,Slezak P,Tribukait B

    更新日期:1984-01-15 00:00:00

  • Risk of second primary malignancies among cancer survivors in the United States, 1992 through 2008.

    abstract:BACKGROUND:In the current study, the authors attempted to describe the incidence, most common sites, and mortality of second primary malignancies among survivors of common cancers. METHODS:The authors identified patients aged ≥18 years who were diagnosed with a primary malignancy from the 10 most common cancer sites (...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30164

    authors: Donin N,Filson C,Drakaki A,Tan HJ,Castillo A,Kwan L,Litwin M,Chamie K

    更新日期:2016-10-01 00:00:00

  • Prognostic factors for patients with localized primary malignant fibrous histiocytoma: a multicenter study of 216 patients with multivariate analysis.

    abstract:BACKGROUND:The purpose of this study was to determine the independent prognostic variables in a well documented subset of 216 patients with localized primary malignant fibrous histiocytomas (MFH). METHODS:Between the years 1980 and 1989, 216 patients with localized, primary (International Union Against Cancer [UICC]/A...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/(SICI)1097-0142(19960501)77:9<1823::AID-CN

    authors: Le Doussal V,Coindre JM,Leroux A,Hacene K,Terrier P,Bui NB,Bonichon F,Collin F,Mandard AM,Contesso G

    更新日期:1996-05-01 00:00:00

  • High dose radiochemotherapy followed by autologous stem cell transplantation in four patients with multiple lymphomatous polyposis.

    abstract:BACKGROUND:Multiple lymphomatous polyposis (MLP) results from gastrointestinal involvement by a B-cell lymphoma that originates from the mantle zone of lymphoid follicles. This well described clinicopathologic entity has a poor prognosis: the rate of complete response after conventional chemotherapy is very low. High d...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950601)75:11<2742::aid-cncr282

    authors: Mahé B,Moreau A,Moreau P,Le Tortorec S,Harousseau JL,Milpied N

    更新日期:1995-06-01 00:00:00

  • Genetic predisposition to breast cancer.

    abstract::Breast cancer is the most common cancer among American women. Because metastatic breast cancer is an incurable disease, efforts to decrease breast cancer mortality have focused on early detection and improved treatment. Identification and analysis of a specific genetic susceptibility could permit detection of suscepti...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19920915)70:4+<1747::aid-cncr282

    authors: Skolnick MH,Cannon-Albright LA

    更新日期:1992-09-15 00:00:00

  • Kaposi's sarcoma in immunosuppression. Possibly the result of a dual viral infection.

    abstract::Kaposi's sarcoma of the gingiva and skin developed in an HIV-negative renal transplant patient while he was receiving cyclosporine therapy. The Kaposi's sarcoma developed shortly after the patient had an acute infection with cytomegalovirus (CMV). Electron microscopy of the tumor's established cell line showed two typ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900201)65:3<492::aid-cncr28206

    authors: Siegal B,Levinton-Kriss S,Schiffer A,Sayar J,Engelberg I,Vonsover A,Ramon Y,Rubinstein E

    更新日期:1990-02-01 00:00:00

  • A functioning catecholamine-secreting vagal body tumor. A case report and review of the literature.

    abstract::There are few cases of catecholamine-secreting paragangliomas of the neck reported in the literature, most of these being of the carotid body and glomus-jugulare type. This report cites the second case of a functioning vagal body tumor secreting norepinephrine predominantly and producing labile hypertension and sympto...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19830901)52:5<932::aid-cncr28205

    authors: Tannir NM,Cortas N,Allam C

    更新日期:1983-09-01 00:00:00

  • Analgesics and cancer of the renal pelvis in New South Wales.

    abstract::A lifetime history of analgesics and tobacco consumption was obtained by a questionnaire completed at interview from 67 patients with carcinoma of the renal pelvis (40 women, 27 men) and 180 control subjects drawn from two sources, friends of patients and persons attending a health screening clinic. Regular consumptio...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820615)49:12<2617::aid-cncr282

    authors: McCredie M,Ford JM,Taylor JS,Stewart JH

    更新日期:1982-06-15 00:00:00

  • Autologous bone marrow rescue in the treatment of advanced tumors of childhood.

    abstract::High-dose multiagent chemotherapy followed by autologous marrow rescue was used in the treatment of 13 patients with Stage III or IV childhood tumors. Encouraging results are being obtained in abdominal lymphoma (1/3 complete remissions (CR); rhabdomyosarcoma (2/4 CR); and retinoblastoma (1/2 CR). In neuroblastoma, th...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820201)49:3<603::aid-cncr28204

    authors: Ekert H,Ellis WM,Waters KD,Tauro GP

    更新日期:1982-02-01 00:00:00

  • Changes in serum levels of Forssman-like antibody in patients with gastric cancer.

    abstract::Because Forssman antigen, one of the most well-known heteroantigens, has been noted in certain cancerous tissues, it would seem that the serum levels of the Forssman antibody of patients with these cancers would be low, owing to the absorption of the naturally occurring antibody by the Forssman antigen-containing canc...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890415)63:8<1528::aid-cncr2820

    authors: Hirayama R,Hirokawa K,Takagi Y,Utsuyama M,Maejima S,Takemura K,Mishima Y,Makinodan T

    更新日期:1989-04-15 00:00:00

  • Optimizing therapy for patients with chronic myelogenous leukemia in chronic phase.

    abstract::Identification of BCR-ABL as the defining leukemogenic event in chronic myelogenous leukemia (CML) revolutionized the treatment of the disease. Imatinib, a potent BCR-ABL inhibitor, is the standard of care for the first-line treatment of patients with chronic-phase CML because of its high long-term response rates and ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.24928

    authors: Kantarjian HM,Cortes J,La Rosée P,Hochhaus A

    更新日期:2010-03-15 00:00:00

  • Natural history and therapy of metastatic renal cell carcinoma: the role of interleukin-2.

    abstract:BACKGROUND:Despite significant advances in understanding the biology of renal cell carcinoma (RCC) during the past decade, metastatic disease remains nearly incurable and a major medical challenge. Because RCC is known to be immunogenic, immunotherapeutic agents such as recombinant human interleukin-2 (rIL-2) and inter...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1097-0142(19971001)80:7<1198::aid-cn

    authors: Bukowski RM

    更新日期:1997-10-01 00:00:00

  • Disseminated coagulopathy in chronic myelomonocytic leukemia.

    abstract::The clinical and laboratory features of nine patients with chronic myelomonocytic leukemia are described. Hepatic or splenic enlargement accompanied by an absolute monocytosis in an older patient with an elevated serum or urine lysozyme and serum vitamin B12 levels were characteristic of the majority of patients in th...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197912)44:6<2249::aid-cncr282044

    authors: Gingrich RD,Burns CP

    更新日期:1979-12-01 00:00:00

  • The role of social support systems in adolescent cancer amputees.

    abstract::Amputation is often a component in the treatment of bone tumors such as osteogenic sarcoma, which is most prevalent in the adolescent age group. Adaptation to cancer and loss of a limb requires a significant multidimensional effort. To examine the role of social support systems, 27 adolescents who had undergone amputa...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850815)56:4<965::aid-cncr28205

    authors: Tebbi CK,Stern M,Boyle M,Mettlin CJ,Mindell ER

    更新日期:1985-08-15 00:00:00

  • Non-Hodgkin's lymphoma in children: an analysis of 122 cases from Argentina.

    abstract::One hundred twenty two children with non-Hodgkin's lymphoma were studied from January 1966 to December 1975. The first group (1966-1972) did not receive an uniform treatment. The second group (1973-1975) entered in a G.A.T.L.A. protocol consisting of: vincristine-prednisone plus surgery and/or radiotherapy as inductio...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(197806)41:6<2372::aid-cncr282041

    authors: Cebrian-Bonesana A,Schvartzman E,Roca-Garcia C,Pependieck C,Sackmann-Muriel S,Ojeda FG,Kvicala R,Pavlovsky S,Lein JM,Penchansky L

    更新日期:1978-06-01 00:00:00