High dose radiochemotherapy followed by autologous stem cell transplantation in four patients with multiple lymphomatous polyposis.

Abstract:

BACKGROUND:Multiple lymphomatous polyposis (MLP) results from gastrointestinal involvement by a B-cell lymphoma that originates from the mantle zone of lymphoid follicles. This well described clinicopathologic entity has a poor prognosis: the rate of complete response after conventional chemotherapy is very low. High dose radiochemotherapy with autologous stem cell transplantation (ASCT), which is one of the most intensive treatments of lymphoma, to the authors' knowledge has not been evaluated in the treatment of MLP. METHODS:Four consecutive patients with MLP were treated with high dose radiochemotherapy and ASCT while they were in partial response after conventional chemotherapy. RESULTS:Three patients achieved a complete clinical and histologic response and one achieved a complete clinical resolution of symptoms, but with persistent histologic lesions. Progression free survival ranged from 11 to 35 months. CONCLUSIONS:Autologous stem cell transplantation for patients with MLP is feasible and may be more effective than conventional chemotherapy. However, further studies are needed to assess the actual place of this type of treatment in the management of MLP.

journal_name

Cancer

journal_title

Cancer

authors

Mahé B,Moreau A,Moreau P,Le Tortorec S,Harousseau JL,Milpied N

doi

10.1002/1097-0142(19950601)75:11<2742::aid-cncr282

subject

Has Abstract

pub_date

1995-06-01 00:00:00

pages

2742-6

issue

11

eissn

0008-543X

issn

1097-0142

journal_volume

75

pub_type

杂志文章

相关文献

CANCER文献大全
  • Cytologic scoring of endometrioid adenocarcinoma of the endometrium.

    abstract:BACKGROUND:Endometrial carcinoma is one of the most frequent malignancies in the female genital tract, and its incidence has been increasing in Japan. Histologic grade is an important factor for organizing treatment strategies, including hormone therapy, and for predicting the prognosis of the patient. The objective of...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20787

    authors: Nishimura Y,Watanabe J,Jobo T,Hattori M,Arai T,Kuramoto H

    更新日期:2005-02-25 00:00:00

  • Synovial sarcoma of the abdominal wall.

    abstract:BACKGROUND:Synovial sarcoma usually arises in the extremities and in close proximity to large joints. Reported examples arising in the anterior abdominal wall are rare. Because most accounts from this location consist of case reports, neither clinical nor prognostic features have been well delineated. METHODS:Twenty-s...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930715)72:2<469::aid-cncr28207

    authors: Fetsch JF,Meis JM

    更新日期:1993-07-15 00:00:00

  • Influence of provider factors and race on uptake of breast cancer gene expression profiling.

    abstract:BACKGROUND:Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider fac...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31222

    authors: Reeder-Hayes KE,Wheeler SB,Baggett CD,Zhou X,Meng K,Roberts MC,Carey LA,Meyer AM

    更新日期:2018-04-15 00:00:00

  • Breast reconstruction. State of the art.

    abstract::Some variant of mastectomy remains the mainstay of the treatment of the primary tumor for the vast majority of the 110,000 new cases of cancer of the breast which will be treated this year in the United States. Reconstruction of the breast after ablation for cancer has become an integral part of the therapeutic regime...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840201)53:3+<809::aid-cncr2820

    authors: Dinner MI,Dowden RV

    更新日期:1984-02-01 00:00:00

  • Probably benign lesions at breast magnetic resonance imaging: preliminary experience in high-risk women.

    abstract:BACKGROUND:The purpose of the current study was to determine the frequency of 'probably benign' interpretations at breast magnetic resonance (MR) imaging screening of high-risk women and the frequency of subsequent malignancy in these women. METHODS:The authors performed a retrospective review of the records of 367 as...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11491

    authors: Liberman L,Morris EA,Benton CL,Abramson AF,Dershaw DD

    更新日期:2003-07-15 00:00:00

  • Peritoneal washing cytology is unnecessary in gynecologic surgery for benign diseases.

    abstract:BACKGROUND:The presence of tumor cells in peritoneal washing cytology specimens taken during surgery affects the staging of many gynecologic malignancies. Peritoneal washings are often collected routinely, even in cases of presumed benign disease. This study was designed to address whether evaluation of these specimens...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19991025)87:5<259::aid-cnc

    authors: Sharifi S,Ducatman BS,Wang HH,Fraser JL

    更新日期:1999-10-25 00:00:00

  • Pelvic computed tomography of breast carcinoma patients. Should it routinely be added to abdominal computed tomography?

    abstract:BACKGROUND:This study was conducted to determine if pelvic computed tomography (CT) should routinely be appended to abdominal CT in the workup of patients with breast carcinoma. METHODS:The abdominal-pelvic CTs of 139 breast carcinoma patients (195 exams) were reviewed. Scans were grouped by indication and whether pel...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Meyer JI,Herts BR,Einstein DM,Singer AA,Budd GT,Cohen MA

    更新日期:1997-02-01 00:00:00

  • A prospective evaluation of the durability of palliative interventions for patients with metastatic breast cancer.

    abstract:BACKGROUND:Although systemic therapy for metastatic breast cancer (MBC) continues to evolve, there are scant data to guide physicians and patients when symptoms develop. In this article, the authors report the frequency and durability of palliative procedures performed in the setting of MBC. METHODS:From July 2002 to ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25034

    authors: Morrogh M,Miner TJ,Park A,Jenckes A,Gonen M,Seidman A,Morrow M,Jaques DP,King TA

    更新日期:2010-07-15 00:00:00

  • Consideration of comorbidity in risk stratification prior to prostate biopsy.

    abstract:BACKGROUND:Previously, the patient-reported Total Illness Burden Index for Prostate Cancer (TIBI-CaP) questionnaire and/or the physician-reported Charlson Comorbidity Index (CCI) have provided assessments of competing comorbidity during treatment decisions for patients with prostate cancer. In the current study, the au...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28044

    authors: Liss MA,Billimek J,Osann K,Cho J,Moskowitz R,Kaplan A,Szabo RJ,Kaplan SH,Greenfield S,Dash A

    更新日期:2013-07-01 00:00:00

  • Long term results of stereotactic brachytherapy used in the initial treatment of patients with glioblastomas.

    abstract:BACKGROUND:Despite optimal therapy with surgery and radiotherapy, the prognosis of patients with glioblastomas remains poor. Stereotactic brachytherapy involves the accurate placement of radioactive isotopes within brain tumors, significantly increasing the dose of radiation that can be delivered to the tumor bed witho...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19940615)73:12<3029::aid-cncr282

    authors: Wen PY,Alexander E 3rd,Black PM,Fine HA,Riese N,Levin JM,Coleman CN,Loeffler JS

    更新日期:1994-06-15 00:00:00

  • Comparison of tumor pathology with duration of survival of North American patients with hepatocellular carcinoma.

    abstract:BACKGROUND:Several of the large studies addressing prognosis and survival from hepatocellular carcinoma (HCC) have been from Europe and Asia, but only a few have emanated from North America. Survival statistics from other parts of the world may not be applicable to the North American population because of etiologic, de...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950815)76:4<579::aid-cncr28207

    authors: Nzeako UC,Goodman ZD,Ishak KG

    更新日期:1995-08-15 00:00:00

  • Fas (CD95/APO-1) and Fas ligand expression in normal pancreas and pancreatic tumors. Implications for immune privilege and immune escape.

    abstract:BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10549

    authors: Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

    更新日期:2002-05-15 00:00:00

  • Differences in the angiogenesis of benign and malignant ovarian tumors, demonstrated by analyses of color Doppler ultrasound, immunohistochemistry, and microvessel density.

    abstract:BACKGROUND:To clarify the differences in angiogenesis between benign and malignant ovarian tumors, the authors examined the immunohistochemical characteristics and the density of tumor vessels in both tumor groups. Intratumoral vascularization was observed preoperatively by transvaginal color Doppler ultrasound. METHO...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Emoto M,Iwasaki H,Mimura K,Kawarabayashi T,Kikuchi M

    更新日期:1997-09-01 00:00:00

  • Differential methylation of cell-free circulating DNA among patients with pancreatic cancer versus chronic pancreatitis.

    abstract:BACKGROUND:: Although patients with chronic pancreatitis (CP) have an increased risk of pancreatic cancer (PanCa), the timely detection of PanCa often is difficult, because the symptoms of CP and PanCa are very similar. Moreover, secondary inflammation may be identified in PanCa, further complicating diagnosis. To impr...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.24893

    authors: Liggett T,Melnikov A,Yi QL,Replogle C,Brand R,Kaul K,Talamonti M,Abrams RA,Levenson V

    更新日期:2010-04-01 00:00:00

  • A nonfunctioning paraganglioma of vagus nerve: an ultrastructural study.

    abstract::The clinical, histological, and ultrastructural aspects of a cervical paraganglioma of the vagus nerve, in a 66-year-old white man, have been discussed in detail. Ultrastructurally, the tumor chief cells contained characteristic membrane-bound and dense-cored neurosecretory granules which ranged in size from 85 millim...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197905)43:5<1689::aid-cncr282043

    authors: Chaudhry AP,Haar JG,Koul A,Nickerson PA

    更新日期:1979-05-01 00:00:00

  • Women age < or = 35 years with primary breast carcinoma: disease features at presentation.

    abstract:BACKGROUND:The purpose of the current study was to describe a population of young patients with breast carcinoma, their characteristics at the time of diagnosis, and the association of these characteristics with disease recurrence and survival. METHODS:Four hundred fifty-two women age < or = 35 years with breast carci...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21070

    authors: Gonzalez-Angulo AM,Broglio K,Kau SW,Eralp Y,Erlichman J,Valero V,Theriault R,Booser D,Buzdar AU,Hortobagyi GN,Arun B

    更新日期:2005-06-15 00:00:00

  • Treatment of intrahepatic malignancy with radiofrequency ablation: radiologic-pathologic correlation.

    abstract:BACKGROUND:Radiofrequency (RF)-induced tissue coagulation represents a new approach for the thermal destruction of tumors within the liver. The purpose of the current study was to 1) assess technique safety; 2) determine the extent and evolution of induced cellular damage; and 3) correlate the observed pathologic effec...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Goldberg SN,Gazelle GS,Compton CC,Mueller PR,Tanabe KK

    更新日期:2000-06-01 00:00:00

  • Past pregnancy is associated with axillary node involvement in women with breast cancer.

    abstract::In 186 women with breast cancer, there was a progressive increase in the proportion of axillary nodal involvement as the number of pregnancies increased from zero to two or more (P = 0.026). Logistic regression analysis demonstrated that this effect was independent of the known relationship of age and tumor size to no...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920215)69:4<981::aid-cncr28206

    authors: Lehrer S,Levine E,Savoretti P,Cropley J,Botstein C,Song HK,Mandell L,Shank B

    更新日期:1992-02-15 00:00:00

  • Immunohistologic detection of lymphocyte subpopulations infiltrating in human oral cancer with special reference to its clinical significance.

    abstract::Cancer tissues from 30 patients with squamous cell carcinoma of the oral cavity were examined immunohistopathologically as to the responsiveness of the host against its own cancer cells in both biopsy and surgically resected specimens from the same patients. Subpopulations of the infiltrating lymphocytes in cancer tis...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840601)53:11<2456::aid-cncr282

    authors: Hiratsuka H,Imamura M,Ishii Y,Kohama G,Kikuchi K

    更新日期:1984-06-01 00:00:00

  • General population norms for the Functional Assessment of Cancer Therapy-Kidney Symptom Index (FKSI).

    abstract:BACKGROUND:Metastatic renal cell cancer is associated with poor long-term survival and has no cure. Traditional clinical endpoints are best supplemented by patient-reported outcomes designed to assess symptoms and function. Normative data was obtained on the National Comprehensive Cancer Network-Functional Assessment o...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27688

    authors: Butt Z,Peipert J,Webster K,Chen C,Cella D

    更新日期:2013-01-15 00:00:00

  • Characterization of FAMPAC, a newly identified human pancreatic carcinoma cell line with a hereditary background.

    abstract:BACKGROUND:A novel pancreatic carcinoma cell line, FAMPAC, was identified from investigation of poorly differentiated pancreatic adenocarcinoma cells found in a patient with a familial predisposition to pancreatic carcinoma. A gene responsible for familial pancreatic carcinoma has not been identified to date. METHODS:...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20193

    authors: Eisold S,Ryschich E,Linnebacher M,Giese T,Nauheimer D,Wild A,Bartsch DK,Büchler MW,Schmidt J

    更新日期:2004-05-01 00:00:00

  • Survivorship programs and care planning.

    abstract::Formal cancer survivorship care is a growing focus internationally. This article provides a broad overview of the national strategies currently in progress for the development of survivorship programs and care plans within the United States and across Europe. The different approaches taken in their implementation, sta...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.28068

    authors: McCabe MS,Faithfull S,Makin W,Wengstrom Y

    更新日期:2013-06-01 00:00:00

  • Dose escalation of gemcitabine concomitant with radiation and cisplatin for nonsmall cell lung cancer: a phase 1-2 study.

    abstract:BACKGROUND:The current study was conducted to evaluate the maximum tolerable dose of weekly gemcitabine administered simultaneously with radiation and cisplatin in patients with locally advanced nonsmall cell lung cancer (NSCLC). METHODS:Patients with stage IIIA/B NSCLC received concurrently 63 grays radiation and 20 ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25366

    authors: Momm F,Kaden M,Tannock I,Schumacher M,Hasse J,Henke M

    更新日期:2010-10-15 00:00:00

  • Relation between smoking cessation and receiving results from three annual spiral chest computed tomography scans for lung carcinoma screening.

    abstract:BACKGROUND:The relation between undergoing a single computed tomography (CT) screening for lung carcinoma and the potential long-term impact on smoking status has been equivocal. Perhaps, recommendations from multiple cancer screenings may promote smoking abstinence among individuals at high risk for lung carcinoma. M...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21045

    authors: Townsend CO,Clark MM,Jett JR,Patten CA,Schroeder DR,Nirelli LM,Swensen SJ,Hurt RD

    更新日期:2005-05-15 00:00:00

  • Extensive en bloc resection of regionally recurrent carcinoma of the rectum.

    abstract::To remove regionally recurrent cancer of the rectum completely, more radical extensive resections were attempted than the conventional ones in 35 patients. Twenty-two patients underwent total pelvic exenteration. In 23, sacral resection was done, combined with other procedures including excision of the entire circumfe...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920615)69:12<2876::aid-cncr282

    authors: Maetani S,Nishikawa T,Iijima Y,Tobe T,Kotoura Y,Shikata J,Yamamura T

    更新日期:1992-06-15 00:00:00

  • Leukemic iritis with hypopyon.

    abstract::A patient with acute lymphoblastic leukemia who had received CNS sanctuary treatment with cranial X-irradiation and intrathecal methotrexate displayed his first sign of relapse as iritis with malignant hypopyon. Treatment included topical and subconjunctival corticosteroids and local X-irradiation. Leukemic infiltrati...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197910)44:4<1511::aid-cncr282044

    authors: Gruenewald RL,Perry MC,Henry PH

    更新日期:1979-10-01 00:00:00

  • Imaging hepatic neoplasms.

    abstract::The various radiologic methods used in the detection of hepatic lesions in the oncologic patient are discussed. The advantages and disadvantages of each imaging technique as well as a new diagnostic approach are also discussed. With the rapid technological advances made in cross-sectional imaging, the authors believe ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Bernardino ME,Lewis E

    更新日期:1982-12-01 00:00:00

  • Hand-mirror variant of acute lymphoblastic leukemia. Evidence for early T-cell lineage in two cases by evaluation with monoclonal antibodies.

    abstract::Lymphoid cells from two patients with hand-mirror variant of acute lymphoblastic leukemia (ALL) were studied with various monoclonal antibodies in attempts to determine their derivation and differentiation. The predominant feature of the malignant bone marrow cells was strong reactivity with antibody 3A1, which stains...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850101)55:1<77::aid-cncr282055

    authors: Gramatzki M,Strong DM,Duval-Arnould B,Morstyn G,Schumacher HR

    更新日期:1985-01-01 00:00:00

  • Hormones and breast cancer.

    abstract::The exact nature of the association between hormones and the development of breast cancer remains uncertain. Studies of endogenous hormone levels and breast cancer suggest a possible role of estrogens and androgens in the cause of breast cancer. Numerous studies have been conducted to assess the risk of breast cancer ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19951115)76:10+<2059::aid-cncr28

    authors: Helzlsouer KJ,Couzi R

    更新日期:1995-11-15 00:00:00

  • Strategies to overcome barriers to early detection of cancer among older adults.

    abstract::If health professionals wish to help increase the number of older adults who get screened regularly to detect cancer at an early stage, they must first understand the barriers to screening that older people experience. This paper discusses the barriers older women face regarding mammography screening. Data from Americ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19941001)74:7+<2190::aid-cncr282

    authors: Rubenstein L

    更新日期:1994-10-01 00:00:00