Hiatal hernia, reflux symptoms, body size, and risk of esophageal and gastric adenocarcinoma.

abstract：:The DNA stemline ploidy was assessed in paraffin-embedded, formalin-fixed primary tumor tissue from 68 patients with nonseminomatous germ cell cancer (NSCGT) clinical Stage I (CS I). Forty-three patients had a single aneuploid (greater than 1C) DNA stemline, whereas 24 patients had multiple aneuploid stemlines. In one...

journal_title：Cancer

authors： Fosså SD,Nesland JM,Waehre H,Amellem O,Pettersen EO

更新日期：1991-04-01 00:00:00

abstract：:A series of 108 prospectively collected human pancreata were evaluated histologically for the presence of acinar cell and ductal lesions. Foci of dysplastic acinar cells were present in 44% of the series. Some of the focal acinar cell abnormalities were similar to atypical acinar cell nodules which have been described...

journal_title：Cancer

authors： Longnecker DS,Shinozuka H,Dekker A

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:The clinical dose of 3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-1-(2-chloroethyl)-1-nitro- sourea hydrochloride (ACNU) is limited by the bone marrow suppression it produces. The authors investigated whether bone marrow transplantation (BMT) associated with a high dose of ACNU could alleviate marrow toxicity ...

journal_title：Cancer

authors： Soma M,Shoin K,Yamashita J

更新日期：1993-01-15 00:00:00

abstract：:Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...

journal_title：Cancer

authors： Reddy S,Saxena VS,Hendrickson F,Deutsch W

更新日期：1981-02-15 00:00:00

abstract：:Radiotherapy was applied to 14 esophageal carcinomas with respiratory tract fistulas using various treatment regimens. Closure of the fistulas was observed in four cases after irradiation at a daily dose of 1.5 Gy. The period of closure was transient in two cases but long-term in the other two. One long-term closure c...

journal_title：Cancer

authors： Yamada S,Takai Y,Ogawa Y,Kakuto Y,Sakamoto K

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Insular thyroid carcinoma was described originally as a tumor with aggressive behavior. However, whether a predominant insular component is an independent factor for poor prognosis is unclear. METHODS:The authors compared the clinical behavior of tumors in three groups of patients with thyroid carcinoma--13...

journal_title：Cancer

authors： Pellegriti G,Giuffrida D,Scollo C,Vigneri R,Regalbuto C,Squatrito S,Belfiore A

更新日期：2002-11-15 00:00:00

abstract：:The serious import of breast cancer lies in its potential for metastatic spread, which probably starts early in the course of the disease. Detection of the lesion when immunocompetence can control the metastases leads to long-term survival. This usually involves detection of unsuspected, preclinical disease. This is t...

journal_title：Cancer

authors： Strax P

更新日期：1984-02-01 00:00:00

abstract：:A controlled trial of surgical adjuvant chemotherapy for breast cancer was carried out using 551 Japanese patients. Single or combined treatment with mitomycin C (0.2 mg/kg i.v. three times within five days postoperatively) and cyclophosphamide (100 mg postoperatively daily for four months or longer) was used after ra...

journal_title：Cancer

authors： Koyama H,Wada T,Takahashi Y,Nishizawa Y,Iwanaga T,Aoki Y,Terasawa T,Kosaki G,Kajita A,Wada A

更新日期：1980-12-01 00:00:00

abstract：:A retrospective analysis of 74 cases of transitional cell carcinoma of the renal pelvis and ureter treated at this institution over the past 30 years is presented. When nephrectomy alone or incomplete nephroureterectomy was performed, subsequent transitional cell carcinoma developed in 30% of the ureteral stumps. Subs...

journal_title：Cancer

authors： Strong DW,Pearse HD

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the results of thyroid fine-needle aspiration (FNA) and to determine the reasons for the discrepancies between the cytologic and histologic diagnoses. METHODS:The authors evaluated the cytologic and histologic results of 133 FNAs obtained from 92 patients who underw...

journal_title：Cancer

authors： Sidawy MK,Del Vecchio DM,Knoll SM

更新日期：1997-08-25 00:00:00

abstract：BACKGROUND:At the time of diagnosis of colorectal carcinoma, 2-3% of patients are likely to be harboring brain metastases, and another 10% of patients will develop brain lesions during the course of their disease. The purpose of this study was to examine the clinical course of a group of patients with metastatic brain ...

journal_title：Cancer

authors： Wroński M,Arbit E

更新日期：1999-04-15 00:00:00

abstract：:Hepatoblastoma differs from the adult type of hepatoma in clinical and pathologic features. The ratio of fucosylation of serum alpha-fetoprotein (AFP) was determined in seven patients with hepatoblastoma and in 21 infants and children with otherwise elevated serum AFP, using the improved technique of lentil agglutinin...

journal_title：Cancer

authors： Tsuchida Y,Honna T,Fukui M,Sakaguchi H,Ishiguro T

更新日期：1989-06-01 00:00:00

abstract：:A patient with metastatic islet cell carcinoma of the pancreas, recurrent peptic ulcer disease, and hypergastrinemia (Zollinger-Ellison syndrome) developed symptomatic hypercalcemia and renal insufficiency; she was treated with streptozotocin after parathyroidectomy failed to control her hypercalcemia. Shortly after s...

journal_title：Cancer

authors： Cryer PE,Hill GJ II

更新日期：1976-12-01 00:00:00

abstract：BACKGROUND:A sedentary life style has been consistently associated with an increased risk of colon cancer, but the evidence for its association with breast and other gynecologic cancers is limited. METHODS:Occupational information for 3783 incident patients with cancer (breast, 2736; corpus uteri, 452; and ovary, 595)...

journal_title：Cancer

authors： Zheng W,Shu XO,McLaughlin JK,Chow WH,Gao YT,Blot WJ

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Microphthalmia transcription factor (MITF)-associated (MiT) tumors are a family of rare malignancies, including alveolar soft part sarcoma (ASPS), clear cell sarcoma (CCS), and translocation-associated renal cell carcinoma (tRCC) that have dysregulated expression of oncogenic MITF family proteins. The MET re...

journal_title：Cancer

authors： Wagner AJ,Goldberg JM,Dubois SG,Choy E,Rosen L,Pappo A,Geller J,Judson I,Hogg D,Senzer N,Davis IJ,Chai F,Waghorne C,Schwartz B,Demetri GD

更新日期：2012-12-01 00:00:00

abstract：:The use of molecular techniques in cytopathology has become an accepted and billable practice for certain applications. Other applications still are in the developmental or experimental stages but may soon be clinically useful. The current study provides a review of these techniques including molecular detection of cl...

journal_title：Cancer

authors： Rimm DL

更新日期：2000-02-25 00:00:00

abstract：BACKGROUND:The AJCC staging system and post-operative nomograms use patient and tumor characteristics to provide prognostic estimates after resection of retroperitoneal sarcoma (RPS). While these variables help to predict survival at the time of diagnosis and resection, the applicability of these prognostic factors to ...

journal_title：Cancer

authors： Abbott AM,Habermann EB,Parsons HM,Tuttle T,Al-Refaie W

更新日期：2012-07-01 00:00:00

abstract：:Lymphocyte cyclic nucleotide content was studied before and after Levamisole administration to cancer patients. Twelve patients with disseminated cancer received 100 mg/m2 on two consecutive days; nine comparable patients with disseminated cancer served as controls. Endogenous cyclic adenosine monophosphate (cAMP) and...

journal_title：Cancer

authors： Lewinski UH,Mavligit GM,Thompson WJ,Hersh EM,Ortez RA

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:Exercise is a modifiable lifestyle risk factor associated with prostate cancer risk reduction. However, whether this association is different as a function of race is unclear. In the current study, the authors attempted to characterize the link between exercise and prostate cancer (CaP) in white and black Am...

journal_title：Cancer

authors： Singh AA,Jones LW,Antonelli JA,Gerber L,Calloway EE,Shuler KH,Freedland SJ,Grant DJ,Hoyo C,Bañez LL

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:To elucidate the influence of long term interferon administration on the rate of occurrence of hepatocellular carcinoma (HCC) in patients with hepatitis B virus (HBV)-related cirrhosis, the authors analyzed 313 consecutive patients with cirrhosis. METHODS:Of the 313 patients, 94 underwent long term intermit...

journal_title：Cancer

authors： Ikeda K,Saitoh S,Suzuki Y,Kobayashi M,Tsubota A,Fukuda M,Koida I,Arase Y,Chayama K,Murashima N,Kumada H

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:The psychological adaptation to a cancer diagnosis is characterized by significant distress. Although distress levels in cancer patients have been reported to be the highest shortly after diagnosis and before treatment, few attempts have been made to study emotional adjustment during the diagnostic period of...

journal_title：Cancer

authors： Perczek RE,Burke MA,Carver CS,Krongrad A,Terris MK

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Hypercalcemia has rarely been reported in patients with Richter's syndrome (RS). In this article, the authors report four cases with complementary pathophysiologic examinations. METHODS:Four patients with hypercalcemia that indicated RS were admitted to the study unit between 1980 and 1994 with the followin...

journal_title：Cancer

authors： Beaudreuil J,Lortholary O,Martin A,Feuillard J,Guillevin L,Lortholary P,Raphael M,Casassus P

更新日期：1997-03-15 00:00:00

abstract：:Two studies were performed to evaluate the safety, tolerability, and efficacy of irinotecan (CPT-11) in the treatment of adults with malignant glioma. Patients with progressive or recurrent malignant gliomas were enrolled. In the first study, CPT-11 was administered once every 3 weeks as a 90-minute intravenous infusi...

journal_title：Cancer

authors： Cloughesy TF,Filka E,Kuhn J,Nelson G,Kabbinavar F,Friedman H,Miller LL,Elfring GL

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:The treatment of patients with hepatocellular carcinoma (HCC) presents a major challenge, because associated cirrhosis limits the choice of chemotherapeutic agents. However, the abundant vascularity of HCC presents an attractive target for antiangiogenic therapy that potentially may be tolerated by cirrhotic...

journal_title：Cancer

authors： Patt YZ,Hassan MM,Lozano RD,Nooka AK,Schnirer II,Zeldis JB,Abbruzzese JL,Brown TD

更新日期：2005-02-15 00:00:00

abstract：:One hundred twenty-three women younger than 70 years of age and at clinical Stages I or II were enrolled in a randomized clinical trial of radical versus extended radical mastectomy. The 5-year survival rates in the radical and extended radical groups were 75 +/- 6.7% and 80 +/- 6.7%, respectively. (Cox P value for co...

journal_title：Cancer

authors： Meier P,Ferguson DJ,Karrison T

更新日期：1985-02-15 00:00:00

abstract：BACKGROUND:BRCA2 gene, located at chromosome 13q12.3, frequently is altered in familial types of cancer in which a "double-hit" inactivation model seems to occur. In contrast, in sporadic forms of cancer there is frequent absence of a second event (point mutations) suggesting that allelic imbalance at the BRCA2 locus m...

journal_title：Cancer

authors： Gorgoulis VG,Kotsinas A,Zacharatos P,Mariatos G,Liloglou T,Tsoli E,Kokotas S,Fassoulas C,Field JK,Kittas C

更新日期：2000-11-01 00:00:00

abstract：:Without organized clinical trials, we are doomed to repeat our mistakes endlessly. There are many genuine conflicts of interest intrinsic to clinical research. Some of these arise from the necessity of admitting that we as physicians do not know the best way to treat every disease or each patient and that all treatmen...

journal_title：Cancer

authors： Hrushesky WJ

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Women treated with tamoxifen for breast cancer are at increased risk of endometrial cancer. This study examines the experience at Roswell Park Cancer Institute (RPCI) with women diagnosed with both endometrial carcinoma (EC) and breast carcinoma (BC) to determine the risk and stage of endometrial carcinoma a...

journal_title：Cancer

authors： Cuenca RE,Giachino J,Arredondo MA,Hempling R,Edge SB

更新日期：1996-05-15 00:00:00

abstract：BACKGROUND:The frequency of RET rearrangements (RET/PTC) in papillary thyroid carcinomas varies significantly according to geographic area, with the greatest incidence reported in the Belarus region, which is iodine-deficient and was contaminated severely after the Chernobyl reactor accident, and with the lowest incide...

journal_title：Cancer

authors： Nakazawa T,Kondo T,Kobayashi Y,Takamura N,Murata S,Kameyama K,Muramatsu A,Ito K,Kobayashi M,Katoh R

更新日期：2005-09-01 00:00:00

abstract：:Malignant schwannomas with rhabdomyoblastic differentiation have been termed malignant "Triton" tumors (MTT). To define the natural history of MTT, we have analyzed our experience (9 cases, the largest series reported) in combination with the 27 previously described in the literature (total 36 cases). This study was i...

journal_title：Cancer

authors： Brooks JS,Freeman M,Enterline HT

更新日期：1985-06-01 00:00:00