Ovarian cancer: incidence and case-control study.

Abstract:

:The incidence of ovarian cancer in Rochester, Minnesota over the 40-year period 1935 through 1974 was determined; and risk factors for epithelial ovarian cancer occurring in Rochester from 1945 to 1974 were examined in 116 patients and 464 controls. Among the characteristics studied, only nulliparity was found to be a significant risk factor--relative risk 1.8. Other suspected risk factors--including hypertension, obesity, age at menopause, prior therapeutic pelvic radiation, and prior exposure to exogenous estrogen--were found not to differ significantly between patients and controls. The ovarian cancer patients were found to have a significantly lower frequency of prior hysterectomy and of unilateral oophorectomy than the control group. Thus out data show that hysterectomy, even when one or both ovaries are preserved, is associated with a lower risk of subsequent ovarian cancer.

journal_name

Cancer

journal_title

Cancer

authors

Annegers JF,Strom H,Decker DG,Dockerty MB,O'Fallon WM

doi

10.1002/1097-0142(197902)43:2<723::aid-cncr2820430

subject

Has Abstract

pub_date

1979-02-01 00:00:00

pages

723-9

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

43

pub_type

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