Abstract:
:The clinical, hematological, and cytogenetic characteristics of a male patient with AMMoL are described. Before treatment a clone with the complex karyotype 45,X,del(7)(q32), t(8;21)(q22;q22) was present in the bone marrow. During partial remission induced by cytostatics, the percentage of normal cells increased, and a cell line having a 46,XY,del(7)(q32) karyotype was found. After four therapy courses, when remission was complete, only chromosomally normal cells were seen. The cytogenetic data suggest that in this case the 8/21 translocation and loss of the Y chromosome were only secondary events.
journal_name
Cancerjournal_title
Cancerauthors
Hustinx TW,Burghouts JT,Scheres JM,Smits APdoi
10.1002/1097-0142(19800115)45:2<285::aid-cncr28204subject
Has Abstractpub_date
1980-01-15 00:00:00pages
285-8issue
2eissn
0008-543Xissn
1097-0142journal_volume
45pub_type
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