Abstract:
:Two cases are reported of patients who developed a hematologic malignancy several years after intravesical chemotherapy of superficial bladder cancer with etoglucid, doxorubicin, and mitomycin C. In one patient, karyotypic abnormalities (-5, 7q-) typical of a therapy induced malignancy were associated with rapid progression of a refractory anemia with excess blasts in transformation to an acute non-lymphocytic leukemia. Intravesical chemotherapy may be associated with a risk of secondary malignancy.
journal_name
Cancerjournal_title
Cancerauthors
Sonneveld P,Kurth KH,Hagemeyer A,Abels Jdoi
10.1002/1097-0142(19900101)65:1<23::aid-cncr282065subject
Has Abstractpub_date
1990-01-01 00:00:00pages
23-5issue
1eissn
0008-543Xissn
1097-0142journal_volume
65pub_type
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