Secondary hematologic neoplasm after intravesical chemotherapy for superficial bladder carcinoma.

Abstract:

:Two cases are reported of patients who developed a hematologic malignancy several years after intravesical chemotherapy of superficial bladder cancer with etoglucid, doxorubicin, and mitomycin C. In one patient, karyotypic abnormalities (-5, 7q-) typical of a therapy induced malignancy were associated with rapid progression of a refractory anemia with excess blasts in transformation to an acute non-lymphocytic leukemia. Intravesical chemotherapy may be associated with a risk of secondary malignancy.

journal_name

Cancer

journal_title

Cancer

authors

Sonneveld P,Kurth KH,Hagemeyer A,Abels J

doi

10.1002/1097-0142(19900101)65:1<23::aid-cncr282065

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

23-5

issue

1

eissn

0008-543X

issn

1097-0142

journal_volume

65

pub_type

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