Cancer-related fatigue: implications for breast cancer survivors.

Abstract:

:Cancer-related fatigue (CRF) has been documented as 1 of the most distressing symptoms reported by breast cancer survivors. CRF affects functioning and impacts quality of life. Possible causal factors include physical conditions, affective and cognitive states, proinflammatory cytokines, and metabolic factors. Several common problems are associated with CRF in women with breast cancer, including treatment side effects, obesity, arm/upper quadrant symptoms, sleep disturbances, psychological effects, and comorbid conditions. In this article, the authors review the state of the knowledge regarding these issues and nonpharmacologic and pharmacologic interventions for CRF. Physical activity and psychosocial interventions are recommended for practice. Numerous limitations of past studies need to be considered in the design of future studies. CRF is prevalent in preoperative, postoperative, and ongoing surveillance phases. Throughout the continuum of care for women with breast cancer, clinicians must screen, further assess as indicated, and treat CRF, because it is associated with emotional distress and limits function and willingness to exercise.

journal_name

Cancer

journal_title

Cancer

authors

Berger AM,Gerber LH,Mayer DK

doi

10.1002/cncr.27475

subject

Has Abstract

pub_date

2012-04-15 00:00:00

pages

2261-9

issue

8 Suppl

eissn

0008-543X

issn

1097-0142

journal_volume

118

pub_type

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