Adenoid cystic carcinoma of the breast metastatic to the kidney. A clinically symptomatic lesion requiring surgical management.


:Adenoid cystic carcinoma (ACC) of the breast is a rare histologic type of breast cancer associated with a good prognosis. A woman who earlier had a pulmonary metastasis surgically resected 6 years postmastectomy developed clinically symptomatic bleeding from a renal metastasis 12 years postmastectomy. An atypical angiographic picture (moderate vascularization) for secondary renal neoplasms was observed. The characteristic histologic features of ACC were present in all specimens; ultrastructural characteristics of ACC were identified in the renal lesion. Successful surgical management of these metachronous solitary metastases demonstrates the therapeutic utility of aggressive management in maintaining disease control of this histologic type of breast cancer.






Herzberg AJ,Bossen EH,Walther PJ




Has Abstract


1991-09-01 00:00:00














  • Immunocytochemical detection using CDX2: An aid for discerning tumor involvement in ascites cytology.

    abstract:BACKGROUND:Although ascites cytology is important for therapeutic strategies, it is difficult to distinguish cancer infiltration from reactive mesothelial proliferation in some patients. In this study, the authors applied CDX2 immunocytochemistry to improve diagnostic accuracy. METHODS:The authors examined the distrib...


    pub_type: 杂志文章


    authors: Kobayashi M,Ueyama Y,Nakanishi H,Ishida H,Takahashi E,Nakamura S,Koshikawa T,Yatabe Y

    更新日期:2006-04-25 00:00:00

  • A study of cyclophosphamide, adriamycin, cis-platinum, and methotrexate in advanced transitional cell carcinoma of the urinary tract.

    abstract::Twenty patients with locally advanced and/or metastatic transitional cell cancer of the urinary tract were treated with cyclophosphamide 500 mg/m2, Adriamycin (doxorubicin) 40 mg/m2 and cis-platinum (CDDP) 40 mg/m2 given every three weeks for 2 cycles, alternating with methotrexate 40 mg/m2 weekly for six weeks (CAP-M...


    pub_type: 杂志文章


    authors: Citrin DL,Hogan TF,Davis TE

    更新日期:1983-01-01 00:00:00

  • Nasopharyngeal carcinoma in childhood and adolescence: a single-institution experience with combined therapy.

    abstract:BACKGROUND:A high cure rate may be attained for locally advanced, undifferentiated nasopharyngeal carcinoma (NPC) in children, provided that a combined modality of treatment is employed. Both local and systemic therapies are necessary. Results at a single pediatric institution were analyzed. METHODS:From November 1988...


    pub_type: 杂志文章


    authors: Zubizarreta PA,D'Antonio G,Raslawski E,Gallo G,Preciado MV,Casak SJ,Scopinaro M,Morales G,Sackmann-Muriel F

    更新日期:2000-08-01 00:00:00

  • Clinical application of intratumoral blood flow study in patients with endometrial carcinoma.

    abstract:BACKGROUND:The objective of this study was to evaluate the correlation between intratumoral blood flow as assessed by color Doppler ultrasound with stage, tumor grade, depth of invasion, and lymph node metastasis in endometrial carcinoma and determine its clinical usefulness. METHODS:Sixty-six patients with endometria...


    pub_type: 临床试验,杂志文章


    authors: Cheng WF,Chen TM,Chen CA,Wu CC,Huang KT,Hsieh CY,Hsieh FJ

    更新日期:1998-05-15 00:00:00

  • Effect of chemotherapy on resting energy expenditure in patients with non-Hodgkin's lymphoma. Results of a sequential study.

    abstract::This study compared the resting energy expenditure (REE) modifications observed during successive intensive identical chemotherapy courses in non-Hodgkin's lymphoma patients to assess indirectly the metabolic changes induced by the cytotoxic effect of drugs on the tumor. With this therapeutic regimen, reduction of tum...


    pub_type: 杂志文章


    authors: Delarue J,Lerebours E,Tilly H,Rimbert A,Hochain P,Guedon C,Piguet H,Colin R

    更新日期:1990-06-01 00:00:00

  • Kinetics of serum HER-2/neu changes in patients with HER-2-positive primary breast cancer after initiation of primary chemotherapy.

    abstract:BACKGROUND:The purpose of the study was to determine the utility of quantitation of the extracellular domain (ECD) of the HER-2/neu receptor in the serum for predicting response to treatment in patients with primary breast cancer receiving neoadjuvant therapy. METHODS:HER-2/neu ECD was measured in sera obtained from 3...


    pub_type: 杂志文章,随机对照试验


    authors: Mazouni C,Hall A,Broglio K,Fritsche H,Andre F,Esteva FJ,Hortobagyi GN,Buzdar AU,Pusztai L,Cristofanilli M

    更新日期:2007-02-01 00:00:00

  • Genetic variations in angiopoietin and pericyte pathways and clinical outcome in patients with resected colorectal liver metastases.

    abstract:BACKGROUND:Genes involved in the angiopoietin and pericyte pathways may become escape mechanisms under antivascular endothelial growth factor (anti-VEGF) therapy. The authors investigated whether variations within genes in these pathways are associated with clinical outcome in patients with colorectal liver metastases ...


    pub_type: 杂志文章


    authors: Stremitzer S,Zhang W,Yang D,Ning Y,Stintzing S,Sebio A,Sunakawa Y,Yamauchi S,Matsusaka S,El-Khoueiry R,Stift J,Wrba F,Gruenberger T,Lenz HJ

    更新日期:2015-06-01 00:00:00

  • Human papillomavirus in cervical cancer and oropharyngeal cancer: One cause, two diseases.

    abstract::Human papillomavirus (HPV) causes greater than 5% of cancers worldwide, including all cervical cancers and an alarmingly increasing proportion of oropharyngeal cancers (OPCs). Despite markedly reduced cervical cancer incidence in industrialized nations with organized screening programs, cervical cancer remains the sec...


    pub_type: 杂志文章,评审


    authors: Berman TA,Schiller JT

    更新日期:2017-06-15 00:00:00

  • Sarcomas (other than Ewing's) of flat bones in children and adolescents. A clinicopathologic study.

    abstract::The clinicopathologic features and response to therapy of 28 patients with non-Ewing's flat bone sarcoma treated at St. Jude Children's Research Hospital, Memphis, Tennessee, over a 25-year period were reviewed. Twenty-two patients had osteosarcoma, four malignant fibrous histiocytoma, one chondrosarcoma, and one fibr...


    pub_type: 杂志文章


    authors: Kellie SJ,Pratt CB,Parham DM,Fleming ID,Meyer WH,Rao BN

    更新日期:1990-02-15 00:00:00

  • Investigations on the significance of the adenoma-carcinoma sequence in the small bowel.

    abstract::In view of the rarity of small-bowel epithelial neoplasms as compared with the case for the large bowel, evidence for an adenoma-carcinoma sequence in the small bowel was studied based on a search for data in the medical literature for the years 1927 through 1986. Sufficiently defined data were found for comparison of...


    pub_type: 杂志文章,评审


    authors: Sellner F

    更新日期:1990-08-15 00:00:00

  • The fine structure of astroblastoma.

    abstract::An astroblastoma in the cerebrum was investigated with the electron microscope. A distinctive feature of the tumor was the radial arrangement of astrocytic cells around the blood vessels. The blood vessels in the tumor commonly exhibited fenestrated endothelial cells. The endothelium was generally surrounded by lamell...


    pub_type: 杂志文章


    authors: Kubota T,Hirano A,Sato K,Yamamoto S

    更新日期:1985-02-15 00:00:00

  • Radiotherapy or surgery for head and neck squamous cell cancer: establishing the baseline for hypopharyngeal carcinoma?

    abstract:BACKGROUND:The authors compared the survival outcomes of radiotherapy+/-salvage surgery to surgery+/-postoperative radiotherapy for patients with squamous cell cancer of the hypopharynx. There was no evidence beyond observational studies and no consensus on the which treatment is most effective for this patient group. ...


    pub_type: 杂志文章


    authors: Hall SF,Groome PA,Irish J,O'Sullivan B

    更新日期:2009-12-15 00:00:00

  • Ultrastructure of osteoblastoma.

    abstract::The ultrastructure of three cases of osteoblastoma is described. The osteoblasts resemble normal osteoblasts with a few exceptions: irregular, indented nuclei, and occasional mitochondria with curved cristae and electron-lucent areas. The osteocytes and osteoclasts basically resemble their normal counterparts. There a...


    pub_type: 杂志文章


    authors: Steiner GC

    更新日期:1977-05-01 00:00:00

  • Immunologic evidence of a strong association between non-Hodgkin lymphoma and simian virus 40.

    abstract:BACKGROUND:Non-Hodgkin lymphoma (NHL), the most common cancer of the lymphatic system, is of unknown etiology. The identification of etiologic factors in the onset of NHL is a key event that could facilitate the prevention and cure of this malignancy. Simian virus 40 (SV40) has been considered an oncogenic agent in the...


    pub_type: 杂志文章


    authors: Tognon M,Luppi M,Corallini A,Taronna A,Barozzi P,Rotondo JC,Comar M,Casali MV,Bovenzi M,D'Agostino A,Vinante F,Rigo A,Ferrarini I,Barbanti-Brodano G,Martini F,Mazzoni E

    更新日期:2015-08-01 00:00:00

  • Metronomic therapy with cyclophosphamide and dexamethasone for prostate carcinoma.

    abstract:BACKGROUND:The current study was designed to evaluate the efficacy and toxicity of the continuous oral administration of a combination of cyclophosphamide (50 mg/day given in the morning) and dexamethasone (1 mg/day given in the evening) in patients with prostate specific antigen (PSA) progression despite single or mul...


    pub_type: 杂志文章


    authors: Glode LM,Barqawi A,Crighton F,Crawford ED,Kerbel R

    更新日期:2003-10-15 00:00:00

  • Hepatoid adenocarcinomas of the stomach. An analysis of seven cases.

    abstract::Hepatoid adenocarcinomas of the stomach are gastric carcinomas with both adenocarcinomatous and hepatocellular differentiations. They usually produce large amounts of alpha-fetoprotein (AFP) with a Concanavalin A-binding property of hepatic type. In this study, these carcinomas occurred in older persons, with the antr...


    pub_type: 杂志文章


    authors: Ishikura H,Kirimoto K,Shamoto M,Miyamoto Y,Yamagiwa H,Itoh T,Aizawa M

    更新日期:1986-07-01 00:00:00

  • Proton therapy for low-grade gliomas: Results from a prospective trial.

    abstract:BACKGROUND:In this prospective study, the authors evaluated potential treatment toxicity and progression-free survival in patients with low-grade glioma who received treatment with proton radiation therapy. METHODS:Twenty patients with World Health Organization grade 2 glioma who were eligible for radiation therapy we...


    pub_type: 临床试验,杂志文章


    authors: Shih HA,Sherman JC,Nachtigall LB,Colvin MK,Fullerton BC,Daartz J,Winrich BK,Batchelor TT,Thornton LT,Mancuso SM,Saums MK,Oh KS,Curry WT,Loeffler JS,Yeap BY

    更新日期:2015-05-15 00:00:00

  • Adjuvant radiotherapy versus combined sequential chemotherapy followed by radiotherapy in the treatment of resected nonsmall cell lung carcinoma. A randomized trial of 267 patients. GETCB (Groupe d'Etude et de Traitement des Cancers Bronchiques).

    abstract:BACKGROUND:The effect of adjuvant chemotherapy after resection of nonsmall cell lung cancer (NSCLC) remains an unresolved question. METHODS:From October, 1982, to November, 1986, 267 patients with resected NSCLC were included in a randomized trial. The adjuvant allocated treatments were either postoperative radiothera...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Dautzenberg B,Chastang C,Arriagada R,Le Chevalier T,Belpomme D,Hurdebourcq M,Lebeau B,Fabre C,Charvolin P,Guérin RA

    更新日期:1995-09-01 00:00:00

  • The prognostic significance of vascular invasion by endometrial carcinoma.

    abstract:BACKGROUND:Recently, invasion of vascular spaces by endometrial carcinoma has received particular attention as a prognostic factor. The goal of the current investigation was to re-examine the effect of vascular invasion on tumor recurrence and survival in patients with endometrial carcinoma. METHODS:Surgical specimens...


    pub_type: 杂志文章


    authors: Inoue Y,Obata K,Abe K,Ohmura G,Doh K,Yoshioka T,Hoshiai H,Noda K

    更新日期:1996-10-01 00:00:00

  • Binding of soybean agglutinin lectin to prostatic hyperplasia and adenocarcinoma.

    abstract::The binding of soybean agglutinin (SBA) lectin to routinely processed surgical pathology material from cases of prostatic hyperplasia, atypical hyperplasia, and adenocarcinoma was studied using an immunoperoxidase technique. Positive staining was obtained in eight of eight cases of nodular hyperplasia, eight of eight ...


    pub_type: 杂志文章


    authors: Loy TS,Kyle J,Bickel JT

    更新日期:1989-04-15 00:00:00

  • The relation of flow cytometry to clinical and biologic characteristics in women with node negative primary breast cancer.

    abstract::Flow cytometry (FC) analysis including DNA index (ploidy status) and cell kinetics (%S and %S + G2/M) was done on frozen tissue of the primary lesions of 101 women with node negative (N-) breast cancer who were studied prospectively. Currently, 19% (19/101) of the patients have recurred. No significant relations have ...


    pub_type: 杂志文章


    authors: Muss HB,Kute TE,Case LD,Smith LR,Booher C,Long R,Kammire L,Gregory B,Brockschmidt JK

    更新日期:1989-11-01 00:00:00

  • Supratentorial gangliogliomas: histopathologic grading and tumor recurrence in 184 patients with a median follow-up of 8 years.

    abstract:BACKGROUND:Supratentorial gangliogliomas (GGs) are rare tumors of the central nervous system and are commonly associated with chronic seizures. To date, only case reports and small series of patients with short-term follow-up have been available for the assessment of the potential of GGs to recur and progress. METHODS...


    pub_type: 杂志文章


    authors: Luyken C,Blümcke I,Fimmers R,Urbach H,Wiestler OD,Schramm J

    更新日期:2004-07-01 00:00:00

  • Prospective evaluation of a chamomile mouthwash for prevention of 5-FU-induced oral mucositis.

    abstract:BACKGROUND:Stomatitis has been found to be a major dose-limiting toxicity from bolus 5-fluorouracil-based (5-FU) chemotherapy regimens, despite the use of oral cryotherapy. Pursuant to preliminary data which suggested that a chamomile mouthwash might ameliorate this toxicity, a prospective trial was developed to test c...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Fidler P,Loprinzi CL,O'Fallon JR,Leitch JM,Lee JK,Hayes DL,Novotny P,Clemens-Schutjer D,Bartel J,Michalak JC

    更新日期:1996-02-01 00:00:00

  • Classic kaposi sarcoma: epidemiology and risk factors.

    abstract:BACKGROUND:Although Kaposi sarcoma (KS) initially was described over a century ago, its biology remains enigmatic and conflicting. Whereas the classic type occurs mainly in older men of Mediterranean or Eastern European backgrounds and is not linked to impairment of the host immune response, iatrogenic and human immuno...


    pub_type: 杂志文章,评审


    authors: Iscovich J,Boffetta P,Franceschi S,Azizi E,Sarid R

    更新日期:2000-02-01 00:00:00

  • Cellular and molecular mechanisms of action of bisphosphonates.

    abstract:BACKGROUND:Bisphosphonates currently are the most important class of antiresorptive agents used in the treatment of metabolic bone diseases, including tumor-associated osteolysis and hypercalcemia, Paget's disease, and osteoporosis. These compounds have high affinity for calcium and therefore target to bone mineral, wh...


    pub_type: 杂志文章,评审


    authors: Rogers MJ,Gordon S,Benford HL,Coxon FP,Luckman SP,Monkkonen J,Frith JC

    更新日期:2000-06-15 00:00:00

  • Participants in prospective, randomized clinical trials for resected non-small cell lung cancer have improved survival compared with nonparticipants in such trials.

    abstract::The survival of 78 patients with resected non-small cell lung cancer entered in prospective, randomized investigational trials is compared to that of a population-based group of control patients not included in such trials. The survival of trial patients is significantly better than that of controls (P less than 0.001...


    pub_type: 临床试验,杂志文章


    authors: Davis S,Wright PW,Schulman SF,Hill LD,Pinkham RD,Johnson LP,Jones TW,Kellogg HB Jr,Radke HM,Sikkema WW

    更新日期:1985-10-01 00:00:00

  • Modern prostate brachytherapy. Prostate specific antigen results in 219 patients with up to 12 years of observed follow-up.

    abstract:BACKGROUND:The purported lack of long term modern prostate brachytherapy outcome data continues to lead many physicians to recommend other, more traditional treatments. This concern for long term results has encouraged the authors to supplement their earlier 10-year follow-up of patients receiving brachytherapy; in the...


    pub_type: 杂志文章


    authors: Ragde H,Korb LJ,Elgamal AA,Grado GL,Nadir BS

    更新日期:2000-07-01 00:00:00

  • Preoperative or postoperative irradiation as adjunctive treatment with radical mastectomy in breast cancer.

    abstract::Results from the standpoint of survival rates and locoregional failures are compared in three series of patients having had a radical mastectomy for breast cancer: (1) radical mastectomy alone for the patients who had essentially outer quadrant lesions and a negative axilla; (2) postoperative irradiation when the axil...


    pub_type: 临床试验,杂志文章


    authors: Rodger A,Montague ED,Fletcher G

    更新日期:1983-04-15 00:00:00

  • Partial splenic embolization for cancer patients with thrombocytopenia requiring systemic chemotherapy.

    abstract:BACKGROUND:Partial splenic embolization (PSE) has been used to improve hematologic parameters related to hypersplenism. The purpose of this study was to review our institutional experience with PSE for cancer patients with thrombocytopenia because of splenic sequestration precluding the administration of systemic thera...


    pub_type: 杂志文章


    authors: Kauffman CR,Mahvash A,Kopetz S,Wolff RA,Ensor J,Wallace MJ

    更新日期:2008-05-15 00:00:00

  • Levamisole in primary breast cancer. A controlled study in conjunction with l-phenylalanine mustard.

    abstract::Between September 1976 and May 1980, 135 patients with operable breast cancer and positive axillary nodes received l-phenylalanine mustard, adjunct to surgery, 0.15 mg/kg for five days, six weekly, and were randomised prospectively to levamisole 150 mg for three days, two weekly, or a placebo. Treatment was continued ...


    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Kay RG,Mason BH,Stephens EJ,Arthur JF,Hitchcock GC,Trindall PL,Rodgers R,Mullins P

    更新日期:1983-06-01 00:00:00