Investigation of taxol as a potential radiation sensitizer.

abstract：BACKGROUND:The prognosis of pediatric patients with nonpilocytic astrocytoma, and in particular those with anaplastic astrocytoma, is somewhat unpredictable. This study used MIB-1 monoclonal antibody, a proliferative marker that can be used in formalin fixed paraffin embedded tissues, to study nonpilocytic pediatric as...

journal_title：Cancer

authors： Ho DM,Wong TT,Hsu CY,Ting LT,Chiang H

更新日期：1998-06-15 00:00:00

abstract：:The survival of 78 patients with resected non-small cell lung cancer entered in prospective, randomized investigational trials is compared to that of a population-based group of control patients not included in such trials. The survival of trial patients is significantly better than that of controls (P less than 0.001...

journal_title：Cancer

authors： Davis S,Wright PW,Schulman SF,Hill LD,Pinkham RD,Johnson LP,Jones TW,Kellogg HB Jr,Radke HM,Sikkema WW

更新日期：1985-10-01 00:00:00

abstract：:Ovarian, fallopian tube, and peritoneal cancers have a similar clinical presentation and are treated similarly, and current evidence supports staging all 3 cancers in a single system. The primary site (i.e. ovary, fallopian tube, or peritoneum) should be designated where possible. The histologic type should be recorde...

journal_title：Cancer

authors： Prat J,FIGO Committee on Gynecologic Oncology.

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Chemoradiation with 5-fluorouracil and mitomycin remains the standard of care for squamous cell carcinoma (SCC) of the anal canal. A prolonged treatment time is associated with inferior disease-specific outcomes. Radiation Therapy Oncology Group trial 0529 demonstrated decreased toxicity and fewer treatment ...

journal_title：Cancer

authors： Elson JK,Kachnic LA,Kharofa JR

更新日期：2018-11-15 00:00:00

abstract：:The clinicopathologic features and response to therapy of 28 patients with non-Ewing's flat bone sarcoma treated at St. Jude Children's Research Hospital, Memphis, Tennessee, over a 25-year period were reviewed. Twenty-two patients had osteosarcoma, four malignant fibrous histiocytoma, one chondrosarcoma, and one fibr...

journal_title：Cancer

authors： Kellie SJ,Pratt CB,Parham DM,Fleming ID,Meyer WH,Rao BN

更新日期：1990-02-15 00:00:00

abstract：BACKGROUND:Some vasoactive drugs have been studied in the hope of altering the vascular permeability and/or blood of tumors to enhance monoclonal antibody (MoAb) uptake. The pretreatment of interleukin-2 (IL-2), one of the vasoactive reagents, produced a generalized vascular permeability, but its function was not tumor...

journal_title：Cancer

authors： Nakamura K,Kubo A

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:Granulocyte-macrophage-colony stimulating factor (GM-CSF) administration stimulates the proliferation of hemopoietic progenitors. Shortly (48-96 hours) after its discontinuation, feedback phenomena occur and the progenitor proliferation rate drops below baseline levels. As the quiescence of hyperplastic bone...

journal_title：Cancer

authors： Aglietta M,Montemurro F,Fagioli F,Volta C,Botto B,Cantonetti M,Racanelli V,Teofili L,Ferrara R,Amadori S,Castoldi GL,Dammacco F,Levis A

更新日期：2000-01-15 00:00:00

abstract：:Malignant fibrous histiocytoma of soft tissues (MFH), a mesenchymal tumor of varied morphologic patterns and cell types, sometimes contains bone and cartilage. Such bony and cartilaginous elements in a pleomorphic MFH may pose a difficult diagnostic challenge. An MFH with bone and cartilage can be distinguished from e...

journal_title：Cancer

authors： Bhagavan BS,Dorfman HD

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:The authors tested a biotherapy regimen involving recombinant interferon-alpha-2a (rIFN-alpha-2a) and recombinant human interleukin-2 (rhIL-2), given in a "decrescendo" schedule over 5 days, for its activity and toxicity in 21 patients who previously had received chemotherapy for advanced melanoma. METHODS:...

journal_title：Cancer

authors： Eton O,Buzaid AC,Bedikian AY,Smith TM,Papadopoulos NE,Ellerhorst JA,Hibberts JL,Legha SS,Benjamin RS

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:The purpose of the current study was to determine the prevalence of low bone mineral density (BMD) (ie, osteopenia) and identify factors associated with low BMD in young adult survivors of childhood acute lymphoblastic leukemia (ALL). METHODS:Dual energy x-ray absorptiometry was used to evaluate BMD in 74 r...

journal_title：Cancer

authors： Thomas IH,Donohue JE,Ness KK,Dengel DR,Baker KS,Gurney JG

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) complicating cirrhosis has a high intrahepatic recurrence rate after treatment by surgical resection or percutaneous ethanol injection (PEI). In this study, certain clinical, biochemical, and pathologic parameters were evaluated as risk factors for intrahepatic tumor recurrence...

journal_title：Cancer

authors： Pompili M,Rapaccini GL,de Luca F,Caturelli E,Astone A,Siena DA,Villani MR,Grattagliano A,Cedrone A,Gasbarrini G

更新日期：1997-04-15 00:00:00

abstract：:Desmosomes, gap junctions and tight junctions are intercellular specializations which have been described in human meningiomas. We report, in five of five meningiomas, including a pulmonary metastasis from a malignant intracranial meningioma, a fourth type of intercellular specialization which is similar to but not id...

journal_title：Cancer

authors： Copeland DD,Bell SW,Shelburne JD

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:This study was performed to evaluate the use of the 1992 International Union Against Cancer (UICC)/American Joint Committee on Cancer (AJCC) T categories for localized prostate cancer treated with radiation therapy and to compare the prognostic power of this system with the Whitmore-Jewett scheme. METHODS:T...

journal_title：Cancer

authors： Zagars GK,Geara FB,Pollack A,von Eschenbach AC

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Although breast-conserving therapy (tumor excision, axillary node dissection, and postoperative radiation) for women with breast cancer yields survival and local recurrence rates comparable with those of modified radical mastectomy, studies suggest that postoperative radiation leads to capsular contractures ...

journal_title：Cancer

authors： Guenther JM,Tokita KM,Giuliano AE

更新日期：1994-05-15 00:00:00

abstract：BACKGROUND:Interleukin-2 (IL-2) is used in the treatment of solid tumors and hematologic malignancies. Sudden death is a rare complication of IL-2 treatment. METHODS:A patient with lymphoma underwent chemoradiotherapy myeloablation and autologous stem cell transplantation. The stem cells were cultured in IL-2 (6000 IU...

journal_title：Cancer

authors： Truica CI,Hansen CH,Garvin DF,Meehan KR

更新日期：1998-09-15 00:00:00

abstract：BACKGROUND:Lung cancer (LC) is the most common fatal malignancy, but there are no useful tumor markers for diagnosis or monitoring. Mucin 1 has an established role as a marker in other malignancies, but has undergone limited assessment in LC. METHODS:Serum from 86 patients with LC and 24 with benign pulmonary disease ...

journal_title：Cancer

authors： Willsher PC,Xing PX,Clarke CP,Ho DW,McKenzie IF

更新日期：1993-11-15 00:00:00

abstract：:Carcinoembryonic antigen (CEA) values in 529 patients treated in two consecutive adjuvant chemotherapy protocols were analyzed to determine if CEA values correlated with disease-free status or prognostic utility. CEA values were evaluated preoperatively, before chemotherapy, at the conclusion of chemotherapy, and duri...

journal_title：Cancer

authors： Theriault RL,Hortobagyi GN,Fritsche HA,Frye D,Martinez R,Buzdar AU

更新日期：1989-03-01 00:00:00

abstract：:An autopsy case of prostaglandin E-producing hepatocellular carcinoma with hypercalcemia is presented in this article. A 72-year-old man showed high serum calcium levels (14.2 to 17.3 mg/100 ml) and hypophosphatemia. The plasma level of immunoreactive parathyroid hormone was below the normal range. Administration of o...

journal_title：Cancer

authors： Ikeda T,Tozuka S,Hasumura Y,Takeuchi J

更新日期：1988-05-01 00:00:00

abstract：:Quantitative counts of ferruginous bodies were performed on digests of lungs from 100 control and 30 lung cancer patients. It was found that the lung cancer group had significantly higher levels, although only 1 patient was known to be occupationally exposed to asbestos. It is suggested that even extremely low levels ...

journal_title：Cancer

authors： Warnock ML,Churg AM

更新日期：1975-04-01 00:00:00

abstract：:Modes of cancer growth and DNA ploidy were studied in 66 patients with mucosal carcinoma of the stomach. The modes of growth were classified into five histologic patterns; elongated tubular (three patients), expansive (18 patients), tubular and solid (14 patients), carcinoma in situ (10 patients) and infiltrative (21 ...

journal_title：Cancer

authors： Okamura T,Korenaga D,Haraguchi M,Tsujitani S,Sugimachi K,Mori M,Enjoji M

更新日期：1987-03-15 00:00:00

abstract：BACKGROUND:A high cure rate may be attained for locally advanced, undifferentiated nasopharyngeal carcinoma (NPC) in children, provided that a combined modality of treatment is employed. Both local and systemic therapies are necessary. Results at a single pediatric institution were analyzed. METHODS:From November 1988...

journal_title：Cancer

authors： Zubizarreta PA,D'Antonio G,Raslawski E,Gallo G,Preciado MV,Casak SJ,Scopinaro M,Morales G,Sackmann-Muriel F

更新日期：2000-08-01 00:00:00

abstract：:The ability of infantile hypercalcemic tumors (three rhabdoid renal tumors, one cellular mesoblastic nephroma, and one hepatoblastoma) to produce parathyroid hormone (PTH) was tested using RNA-DNA hybridization. Results were compared with those obtained in one lung epidermoid carcinoma and one parathyroid adenoma from...

journal_title：Cancer

authors： Rousseau-Merck MF,de Keyzer Y,Bourdeau A,Cournot G,Mercier F,Nezelof C

更新日期：1988-07-15 00:00:00

abstract：:Alpha Heavy Chain Disease has generally been described in the Mediterranean area in young people with a diffuse gastrointestinal lymphoma and malabsorption. We describe a patient from the United States with polypoid lymphoma of the gastrointestinal tract and a prolonged clinical course, who had the characteristic alph...

journal_title：Cancer

authors： Cohen HJ,Gonzalvo A,Krook J,Thompson TT,Kremer WB

更新日期：1978-03-01 00:00:00

abstract：:A 30-year-old man underwent orchiectomy in 1962 for a testicular carcinoma composed of choriocarcinomatous and teratocarcinomatous elements. Bilateral pulmonary metastases regressed completely on combination chemotherapy. However, a cerebral metastasis developed in 1963 and caused severe neurologic signs. At craniotom...

journal_title：Cancer

authors： Stolinsky DC

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Colorectal cancer patients undergoing chemotherapy (CT) are likely to experience multiple concurrent toxicities that, rather than appearing singularly, may be associated with one another. Graphic and tabular representations of distance matrices were used to identify associations between toxicities and to def...

journal_title：Cancer

authors： Aprile G,Ramoni M,Keefe D,Sonis S

更新日期：2008-01-15 00:00:00

abstract：BACKGROUND:To propose 'never-smoking nonsmall cell lung cancer (NSCLC)' as a separate entity, the clinicopathologic differences of operable NSCLC between never-smoking patients and patients with a history of smoking were investigated. METHODS:The medical records of 1405 patients with primary NSCLC who underwent a comp...

journal_title：Cancer

authors： Yano T,Miura N,Takenaka T,Haro A,Okazaki H,Ohba T,Kouso H,Kometani T,Shoji F,Maehara Y

更新日期：2008-09-01 00:00:00

abstract：:The natural history of the development of neoplasia in experimental systems may be separated into at least three different stages, those of initiation, promotion and progression. Evidence for such distinct stages has been demonstrated in at least half a dozen different experimental systems. The stage of promotion is t...

journal_title：Cancer

authors： Pitot HC

更新日期：1982-03-15 00:00:00

abstract：:Over the last decade, new cytotoxic treatments and targeted therapies have altered treatment paradigms for patients with metastatic non-small cell lung cancer (NSCLC). We sought to analyze the impact of histology and biomarker selection criteria on outcomes of clinical trials in metastatic NSCLC reported over the last...

journal_title：Cancer

authors： Gentzler RD,Yentz SE,Johnson ML,Rademaker AW,Patel JD

更新日期：2014-12-15 00:00:00

abstract：BACKGROUND:Ordinary craniopharyngiomas affecting sellar regions of children and preadolescents are composed of ameloblastomatous and/or squamous constituents. The authors encountered an autopsy case of a stillborn infant with a large craniopharyngioma with unusual manifestations. METHODS:The craniopharyngioma was anal...

journal_title：Cancer

authors： Yamada H,Haratake J,Narasaki T,Oda T

更新日期：1995-06-15 00:00:00

abstract：:Two consecutive trials for the treatment of childhood non-Hodgkin's lymphoma were evaluated, carried out by the same cooperative groups. Group A: From June, 1973 to December, 1975, 50 evaluable patients under 16 years of age participated in a study that included vincristine and prednisone plus surgery and/or radiother...

journal_title：Cancer

authors： Sackmann-Muriel F,Diez B,Schvartzman E,Braier JL,Schwartz L,Gallo G,Pavlovsky S

更新日期：1984-12-15 00:00:00