Growth mode and DNA ploidy in mucosal carcinomas of the stomach.

abstract：BACKGROUND:Little is known about the size and characteristics of the decision-support networks of women newly diagnosed with breast cancer and whether their involvement improves breast cancer treatment decisions. METHODS:A population-based sample of patients newly diagnosed with breast cancer in 2014 and 2015, as repo...

journal_title：Cancer

authors： Wallner LP,Li Y,McLeod MC,Hamilton AS,Ward KC,Veenstra CM,An LC,Janz NK,Katz SJ,Hawley ST

更新日期：2017-10-15 00:00:00

abstract：:The present study was carried out to investigate a distinctive type of carcinoma of the uterine cervix categorized under the designation as circumscribed carcinoma with lymphocytic infiltration. Grossly this carcinoma is characterized by defined circumscription with a superficial ulceration. A microscropic feature cha...

journal_title：Cancer

authors： Hasumi K,Sugano H,Sakamoto G,Masubuchi K,Kubo H

更新日期：1977-06-01 00:00:00

abstract：:A 28-year-old man with evidence of feminization was demonstrated after 4 years of investigation to have a estrogen-secreting interstitial cell tumor. Such feminizing neoplasms are uncommon, only 37 having been described. They are usually benign and are characterized by gynecomastia, a testicular mass and, with lesser ...

journal_title：Cancer

authors： Gabrilove JL,Nicolis GL,Mitty HA,Sohval AR

更新日期：1975-04-01 00:00:00

abstract：BACKGROUND:New biologic prognostic factors are needed to guide the treatment of patients with colorectal cancer. The prognostic value of the altered expression of the cell surface glycoprotein gp78, which has been implicated in tumor-cell invasion and metastasis as an autocrine motility factor (AMF) receptor, was evalu...

journal_title：Cancer

authors： Nakamori S,Watanabe H,Kameyama M,Imaoka S,Furukawa H,Ishikawa O,Sasaki Y,Kabuto T,Raz A

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:Hypothyroidism is a potential complication after radiation therapy (RT) when treatment fields include the thyroid. The authors assessed risk of hypothyroidism in breast cancer patients who were receiving RT to a supraclavicular field, which typically includes a portion of thyroid. METHODS:The authors identi...

journal_title：Cancer

authors： Smith GL,Smith BD,Giordano SH,Shih YC,Woodward WA,Strom EA,Perkins GH,Tereffe W,Yu TK,Buchholz TA

更新日期：2008-03-15 00:00:00

abstract：:Carcinoembryonic antigen (CEA) determinations performed in the milk of a nursing mother with an inoperable breast cancer revealed a 10-15-fold higher level compared with CEA levels in the milk of healthy nursing women. CEA was highly elevated in the milk of the tumor-bearing breast (1100 +/- 100 ng/ml) and moderately ...

journal_title：Cancer

authors： Bartal AH,Kahana L,Yarom J

更新日期：1980-11-01 00:00:00

abstract：BACKGROUND:Allelic deletions are frequent genetic alterations in patients with hepatocellular carcinoma (HCC). METHODS:To evaluate the allelic losses on chromosome 8p in HCC patients and define their clinicopathologic significance, we performed high-density allelotyping on 8p in 60 patients with HCC and analyzed the c...

journal_title：Cancer

authors： Chan KL,Lee JM,Guan XY,Fan ST,Ng IO

更新日期：2002-06-15 00:00:00

abstract：BACKGROUND:In a previous phase 2 trial, axitinib was active and well tolerated in patients with advanced thyroid cancer. In this second phase 2 trial, the efficacy and safety of axitinib were evaluated further in this population, and pharmacokinetic/pharmacodynamic relationships and patient-reported outcomes were asses...

journal_title：Cancer

authors： Locati LD,Licitra L,Agate L,Ou SH,Boucher A,Jarzab B,Qin S,Kane MA,Wirth LJ,Chen C,Kim S,Ingrosso A,Pithavala YK,Bycott P,Cohen EE

更新日期：2014-09-01 00:00:00

abstract：:We present a case with the unusual association of Graves' disease and functioning pulmonary metastases of follicular thyroid carcinoma. Unlike other reports of thyroid cancer and thyrotoxicosis, this patient's hyperthyroidism was related to a hyperfunctioning primary thyroid neoplasm and not merely to large amounts of...

journal_title：Cancer

authors： Grayzel EF,Bennett B

更新日期：1979-05-01 00:00:00

abstract：BACKGROUND:Primary central nervous system lymphoma (PCNSL) is the most common brain tumor occurring in patients with acquired immune deficiency syndrome (AIDS). After diagnosis of PCNSL, the median survival time is 2-5 months with treatment with whole brain irradiation (WBI). METHODS:Four (of approximately 40) patient...

journal_title：Cancer

authors： Chamberlain MC

更新日期：1994-03-15 00:00:00

abstract：:Forty-five immunocompetent patients with solid tumors were immunized with BCG, PPD, and tumor cells. The methods were practical, but the morbidity was significant, including painful draining ulcerations at vaccine sites, possible enhancement of tumor growth in three patients, and the discovery at autopsy of systemic t...

journal_title：Cancer

authors： Gerner RE,Moore GE

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:BRAF inhibitors are effective in melanoma and other cancers with BRAF mutations; however, patients ultimately develop therapeutic resistance through the activation of alternative signaling pathways such as RAF/RAS or MET. The authors hypothesized that combining the BRAF inhibitor vemurafenib with either the ...

journal_title：Cancer

authors： Janku F,Sakamuri D,Kato S,Huang HJ,Call SG,Naing A,Holley VR,Patel SP,Amaria RN,Falchook GS,Piha-Paul SA,Zinner RG,Tsimberidou AM,Hong DS,Meric-Bernstam F

更新日期：2021-02-01 00:00:00

abstract：:The fine structure of a pineal germinoma was studied in tissue blocks and in tissue culture. The original tumor contained large primary tumor cells, lymphocytes, macrophages, plasma cells, and astrocytes. The large primary tumor cells were characterized by large nuclei, relatively scanty organelles, abundant glycogen,...

journal_title：Cancer

authors： Markesbery WR,Brooks WH,Milsow L,Mortara RH

更新日期：1976-01-01 00:00:00

abstract：:Breast cancer specimens from 600 women were assayed for estrogen receptors (ER) using an immunocytochemical assay (ICA) employing the monoclonal antiestrophilin antibody H222 Sp gamma. Results showed significant correlation with biochemical ER determinations as well as with tumor grade and menopausal status. In 449 ca...

journal_title：Cancer

authors： Pertschuk LP,Kim DS,Nayer K,Feldman JG,Eisenberg KB,Carter AC,Rong ZT,Thelmo WL,Fleisher J,Greene GL

更新日期：1990-10-15 00:00:00

abstract：BACKGROUND:Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS:By using population-based registry linkage information from the US Transpla...

journal_title：Cancer

authors： Tota JE,Engels EA,Madeleine MM,Clarke CA,Lynch CF,Ortiz AP,Hernandez BY,Chaturvedi AK

更新日期：2018-06-15 00:00:00

abstract：:Sequential corrected creatinine clearance (CCC) evaluations were obtained in 30 patients treated with intra-arterial and/or intravenous cis-diamminedichloroplatinum-II (CDP). The dose was 150 mg/M2 administered with mannitol diuresis at 2 to 3 weekly intervals. Four hundred fifty-three courses were administered (range...

journal_title：Cancer

authors： Jaffe N,Keifer R 3rd,Robertson R,Cangir A,Wang A

更新日期：1987-05-01 00:00:00

abstract：:Antibodies to herpes simplex viral-induced antigens (HSVIA) were assayed by an indirect immunofluorescent technique in 93 regular cigarette smokers, 75 of whom also imbibed alcoholic beverages. Controls were 94 nonsmoking, nondrinking volunteers matched with the smoker for age and sex. IgA antibodies to HSVIA were det...

journal_title：Cancer

authors： Smith HG,Horowitz N,Silverman NA,Henson DE,Chretien PB

更新日期：1976-09-01 00:00:00

abstract：:The clinical and laboratory features of nine patients with chronic myelomonocytic leukemia are described. Hepatic or splenic enlargement accompanied by an absolute monocytosis in an older patient with an elevated serum or urine lysozyme and serum vitamin B12 levels were characteristic of the majority of patients in th...

journal_title：Cancer

authors： Gingrich RD,Burns CP

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:The prognostic relevance of activated oncogenes and oncoproteins has not been well studied in papillary thyroid cancer, which is slow-growing, with only regional spread in most cases. Therefore, the influence of some protein markers and tumor cell proliferation on disease progress in a series of patients wit...

journal_title：Cancer

authors： Akslen LA,Varhaug JE

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:Gastric mucosal blood flow, secretion of mucin, and renewal of the gastric mucosal cells are considered to be defensive factors against gastric mucosal injuries. These factors are regulated by the nervous system and neuropeptides. Gastrectomy may affect this regulation and induce gastric mucosal changes, suc...

journal_title：Cancer

authors： Kaminishi M,Shimizu N,Shiomoyama S,Yamaguchi H,Ogawa T,Sakai S,Kuramoto S,Oohara T

更新日期：1995-03-15 00:00:00

abstract：:From November 1987 to April 1989, 1000 women 40 years or older underwent screening vaginal sonography at the University of Kentucky Medical Center (Lexington, KY). Patients included in this investigation were all asymptomatic and had no known pelvic abnormalities. Each ovary was measured in three planes and ovarian vo...

journal_title：Cancer

authors： van Nagell JR Jr,Higgins RV,Donaldson ES,Gallion HH,Powell DE,Pavlik EJ,Woods CH,Thompson EA

更新日期：1990-02-01 00:00:00

abstract：:A pathology review of breast cancers in Japanese and Caucasian women indicates more numerous in situ carcinomas in the Japanese. Carcinomas with uniform nuclei were also more numerous among Japanese. Japanese women showed more extensive lymphocytic infiltrates adjacent to their tumors than did Caucasian women, and als...

journal_title：Cancer

authors： Stemmermann GN,Catts A,Fukunaga FH,Horie A,Nomura AM

更新日期：1985-07-01 00:00:00

abstract：:The disposition of many drugs in obesity is altered, although little is known of the effect of obesity on the pharmacokinetics of anti-cancer drugs. In this report the authors describe the pharmacokinetics of high-dose methotrexate in an obese woman (184% ideal body weight) with osteosarcoma. For this patient, both th...

journal_title：Cancer

authors： Fleming RA,Eldridge RM,Johnson CE,Stewart CF

更新日期：1991-09-15 00:00:00

abstract：:Disagreement persists about the superiority of Reagan and Ng's method over that of Broders' for the histologic grading of squamous carcinoma of the cervix. Uncertainty about the predictive value and reproducibility of any of the grading methods prompted a comparison of factors previously suggested as indicating the bi...

journal_title：Cancer

authors： Zaino RJ,Ward S,Delgado G,Bundy B,Gore H,Fetter G,Ganjei P,Frauenhoffer E

更新日期：1992-04-01 00:00:00

abstract：:The 136 patients who underwent total laryngectomy as the primary treatment for squamous cell carcinoma of the glottis at the Mayo Clinic in 1970 through 1981 were followed by retrospective record review for at least 4 years or until death, local recurrence, neck recurrence, or delayed neck metastasis. Cancer recurred ...

journal_title：Cancer

authors： Foote RL,Buskirk SJ,Stanley RJ,Grambsch PM,Olsen KD,DeSanto LW,Earle JD,Weiland LH

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:The chromophobe variant of renal cell carcinoma is a recently described and frequently unrecognized tumor. Because the prognosis of the chromophobe variant appears to be intermediate between that of oncocytoma and the clear cell variant of renal cell carcinoma, accurate diagnosis may be important for appropr...

journal_title：Cancer

authors： Granter SR,Renshaw AA

更新日期：1997-04-25 00:00:00

abstract：BACKGROUND:The poor prognosis reported for patients with high-grade glial neoplasms indicates a need for the development of multimodality therapeutic approaches. The addition of chemotherapy has contributed variably to increased survival. The objective of the current study (Southwest Oncology Group [SWOG] 9016) was to ...

journal_title：Cancer

authors： Blumenthal DT,Rankin C,Eyre HJ,Livingston RB,Spence AM,Stelzer KJ,Rushing EJ,Berger MS,Rivkin SE,Cohn AL,Petersdorf SH

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Medical records of 50 patients with malignant mesothelioma were reviewed to determine the clinical features and factors influencing survival. METHODS:Charts of all patients whose conditions were diagnosed as malignant mesothelioma were abstracted and analyzed by statistical software. RESULTS:The male-to-fe...

journal_title：Cancer

authors： Sridhar KS,Doria R,Raub WA Jr,Thurer RJ,Saldana M

更新日期：1992-12-15 00:00:00

abstract：:From 1959 to 1986, 24 patients with primary malignant tumors of the trachea received radiotherapy as all or part of treatment. Common presentations included respiratory symptoms in 20 patients and hemoptysis in 15. Thirteen patients had squamous carcinomas with undifferentiated and adenoid cystic cancers in five and f...

journal_title：Cancer

authors： Fields JN,Rigaud G,Emami BN

更新日期：1989-06-15 00:00:00

abstract：:Bladder cancer is one of the malignancies for which considerable information is available regarding molecular pathogenesis and genetic predictors of natural history, as well as response to treatment. Loss of heterozygosity of chromosome 9 appears to be essential to the genesis of superficial bladder cancer, and mutati...

journal_title：Cancer

authors： Raghavan D

更新日期：2003-04-15 00:00:00