Feasibility study of active immunotherapy in patients with solid tumors.

abstract：BACKGROUND:Several of the large studies addressing prognosis and survival from hepatocellular carcinoma (HCC) have been from Europe and Asia, but only a few have emanated from North America. Survival statistics from other parts of the world may not be applicable to the North American population because of etiologic, de...

journal_title：Cancer

authors： Nzeako UC,Goodman ZD,Ishak KG

更新日期：1995-08-15 00:00:00

abstract：:Patients with small cell bronchogenic carcinoma, in a study utilizing laminar-air-flow-protected environments, oral prophylactic broad spectrum non-absorbable antibiotics (PNAA), and intensive combination chemotherapy, were examined to determine the effects of PNAA on serum biochemical values and on gastrointestinal a...

journal_title：Cancer

authors： Cohen MH,Creaven PJ,Fossieck BE,Johnston AV,Williams CL

更新日期：1976-10-01 00:00:00

abstract：BACKGROUND:Despite known benefits to needle biopsy for suspicious breast lesions, variability in the use of this technique has been documented in practice. We sought to study the use of needle biopsy and open surgical biopsy in women with breast cancer, predictors of needle biopsy use, and the effect of biopsy choice o...

journal_title：Cancer

authors： Friese CR,Neville BA,Edge SB,Hassett MJ,Earle CC

更新日期：2009-02-15 00:00:00

abstract：BACKGROUND:The incidence of metastasis to the thyroid gland in autopsy series varies from 1.25% to 24%. Metastasis to the thyroid gland is usually considered a terminal event, and the effectiveness of conventional treatment has been questioned. The authors assessed the effects of current methods of diagnosis and treatm...

journal_title：Cancer

authors： Nakhjavani MK,Gharib H,Goellner JR,van Heerden JA

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:The prognostic impact of DNA mismatch repair (MMR) status remains controversial in patients with stage III colon cancer who are treated with adjuvant chemotherapy (AC). The aim of this study was to evaluate the survival outcome of AC in deficient mismatch repair (dMMR)/microsatellite instable (MSI) stage III...

journal_title：Cancer

authors： Shaib WL,Zakka KM,Jiang R,Yan M,Alese OB,Akce M,Wu C,Behera M,El-Rayes BF

更新日期：2020-09-15 00:00:00

abstract：:Meningeal carcinomatosis can appear with a variety of neurologic signs and symptoms. Alterations in respiratory control have not been reported in this syndrome or in neurologic syndromes associated with systemic cancer. The authors report on a case of documented leptomeningeal carcinoma from breast cancer presenting a...

journal_title：Cancer

authors： Marcus FS,Dandolos EM,Friedman MA

更新日期：1981-03-01 00:00:00

abstract：:Twenty-four patients with metastatic cancer of the choroid were seen in the Department of Therapeutic Radiology, Rush-Presbyterian--St. Luke's Medical Center, Chicago, between 1964 and 1975. One fourth of the patients had involvement in both eyes, for a total of 30 eyes involved with metastatic cancer. The most common...

journal_title：Cancer

authors： Reddy S,Saxena VS,Hendrickson F,Deutsch W

更新日期：1981-02-15 00:00:00

abstract：:The diagnosis of breast cancer brings with it significant psychosocial concerns and questions. Part of providing comprehensive care for a woman with breast cancer requires the physician to be aware of the Reach To Recovery Program, which is a peer modeling program provided by the American Cancer Society. The women who...

journal_title：Cancer

authors： Rinehart ME

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND:This study was performed to evaluate the use of the 1992 International Union Against Cancer (UICC)/American Joint Committee on Cancer (AJCC) T categories for localized prostate cancer treated with radiation therapy and to compare the prognostic power of this system with the Whitmore-Jewett scheme. METHODS:T...

journal_title：Cancer

authors： Zagars GK,Geara FB,Pollack A,von Eschenbach AC

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Fas-expressing cytotoxic T lymphocytes (CTLs) are important antitumor immune effector cells in patients with hepatocellular carcinoma (HCC). The role of transforming growth factor beta 1 (TGF-beta1) in modulating the expression of Fas by CTLs is not known in HCC. The objectives of this study were to characte...

journal_title：Cancer

authors： Yuen MF,Hughes RD,Heneghan MA,Langley PG,Norris S

更新日期：2001-10-15 00:00:00

abstract：:There is a growing body of basic science and epidemiologic evidence to support a research thrust to determine whether several natural or synthetic agents, given alone or together, can lower cancer incidence. Candidate agents include analogs of vitamin A and the vitamin A precursor, beta-carotene, vitamins C and E, and...

journal_title：Cancer

authors： Malone WF,Kelloff GJ,Pierson H,Greenwald P

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:This study was performed to develop a sensitive method for the detection of circulating hepatocellular carcinoma (HCC) cells in peripheral blood, in advance of the diagnosis of distant metastasis of HCC by conventional means. METHODS:Peripheral blood (5 ml) samples were obtained from 64 patients with HCC an...

journal_title：Cancer

authors： Komeda T,Fukuda Y,Sando T,Kita R,Furukawa M,Nishida N,Amenomori M,Nakao K

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic cell transplantation (HCT) is a curative therapy for patients with acute myeloid leukemia (AML). However, post-HCT relapse and regimen-related toxicity remain significant barriers to long-term survival. In recent years, new conditioning regimens have been explored to improve transpla...

journal_title：Cancer

authors： Nagler A,Labopin M,Beelen D,Ciceri F,Volin L,Shimoni A,Foá R,Milpied N,Peccatori J,Polge E,Mailhol A,Mohty M,Savani BN

更新日期：2017-07-15 00:00:00

abstract：BACKGROUND:Cancer survivors face psychosocial issues that increase their risk of suicide. This study examined the risk of suicide across cancer sites, with a focus on survivors of head and neck cancer (HNC). METHODS:The Surveillance, Epidemiology, and End Results 18-registry database (from 2000 to 2014) was queried fo...

journal_title：Cancer

authors： Osazuwa-Peters N,Simpson MC,Zhao L,Boakye EA,Olomukoro SI,Deshields T,Loux TM,Varvares MA,Schootman M

更新日期：2018-10-15 00:00:00

abstract：:The following case report describes a 22-year-old healthy man, non-smoker, non-drinker, who developed a squamous cell carcinoma of the buccal mucosa. The appearance of this unusual tumor in an unexpected clinical setting was unexplained until it was discovered that the patient had a lifetime habit of chewing plastic m...

journal_title：Cancer

authors： Casterline CL,Casterline PF,Jaques DA

更新日期：1977-04-01 00:00:00

abstract：BACKGROUND:Recommendations for pretreatment evaluation and treatment of cervical cancer have significantly evolved over the last decade because of the results of multiple randomized studies comparing the addition of platin-based chemoradiation as well as the widespread dissemination and use of imaging modalities. This ...

journal_title：Cancer

authors： Trimble EL,Harlan LC,Gius D,Stevens J,Schwartz SM

更新日期：2008-08-15 00:00:00

abstract：:High dose methotrexate followed by citrovorum factor reversal has been utilized in twenty-six patients with advanced cancer. Four of 10 patients with head and neck cancer had an objective response. One of 7 patients with metastatic osteosarcoma to the lungs had stabilization with twenty treatments over 23 months. One ...

journal_title：Cancer

authors： Ambinder EP,Perloff M,Ohnuma T,Biller HF,Holland JF

更新日期：1979-04-01 00:00:00

abstract：:Patients with advanced head and neck cancer have significant reduction in their circulating lymphocyte mass which is reflected in decreased numbers of T cells, Fc receptor cells, and in derangements of T lymphocyte functions, i.e., decreased responsiveness to several dilutions of phytohemagglutinin and lack of develop...

journal_title：Cancer

authors： Zighelboim J,Dorey F,Parker NH,Calcaterra T,Ward P,Fahey JL

更新日期：1979-07-01 00:00:00

abstract：:A high percentage of children with Wilms' tumor are cured with multimodal treatment. A small percentage of these children will develop second tumors, perhaps related to a genetic predisposition to neoplasia or possibly secondary to the treatment utilized for Wilms' tumor. Malignant mesothelioma has been associated wit...

journal_title：Cancer

authors： Antman KH,Ruxer RL Jr,Aisner J,Vawter G

更新日期：1984-07-15 00:00:00

abstract：BACKGROUND:Conflicting results have been obtained regarding blood flow distribution to liver tumors. The emphasis on portal vein perfusion has had a great impact on the design of treatment protocols. METHODS:Double microsphere technique with reference organ sampling was used for the measurement of hepatic artery and p...

journal_title：Cancer

authors： Wang LQ,Persson BG,Bergqvist L,Bengmark S

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:The current study was performed to describe frequencies and risk factors of altered oral health and odontogenesis in childhood cancer survivors. METHODS:In total, 9308 survivors who were diagnosed between 1970 and 1986 and 2951 siblings from the Childhood Cancer Survivor Study completed a survey that contai...

journal_title：Cancer

authors： Kaste SC,Goodman P,Leisenring W,Stovall M,Hayashi RJ,Yeazel M,Beiraghi S,Hudson MM,Sklar CA,Robison LL,Baker KS

更新日期：2009-12-15 00:00:00

abstract：:Poor drug compliance may cause a decreased survival of children with malignancies. Children who fail to take their medications are not receiving optimum amounts of chemotherapy and suboptimal therapy causes a shortened survival in children with cancer. This is a study of prednisone compliance in 52 children with cance...

journal_title：Cancer

authors： Smith SD,Rosen D,Trueworthy RC,Lowman JT

更新日期：1979-01-01 00:00:00

abstract：BACKGROUND:Surveillance, Epidemiology, and End Results (SEER) data are frequently used to examine receipt of adjuvant radiotherapy (RT), but to the authors' knowledge the accuracy of data regarding second-course treatments is unknown. METHODS:Using SEER-Medicare-linked data, the authors identified a cohort of men who ...

journal_title：Cancer

authors： Wang K,Sheets NC,Basak R,Chen RC

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Inactivation of the tumor suppressor gene PTEN/MMAC1/TEP1, located on chromosome 10q23, is a common event in advanced stages of diverse human malignancies. However, the prognostic role of PTEN expression in patients with hepatocellular carcinoma (HCC) has not been characterized. METHODS:One hundred five res...

journal_title：Cancer

authors： Hu TH,Huang CC,Lin PR,Chang HW,Ger LP,Lin YW,Changchien CS,Lee CM,Tai MH

更新日期：2003-04-15 00:00:00

abstract：BACKGROUND:The current study was performed to compare the value of sentinel lymph node dissection (SND) and axillary lymph node dissection (AND) in improving the utility-adjusted survival for early-stage breast carcinoma patients. METHODS:A number needed to treat (NNT) analysis was used to compare SND with AND. In the...

journal_title：Cancer

authors： Jani AB,Basu A,Heimann R,Hellman S

更新日期：2003-01-15 00:00:00

abstract：:Acquired myeloperoxidase deficiency has been reported in several hematological malignancies. The clinical course of a patient with acute myelomonocytic leukemia is described which was characterized by staphylococcal infections prior to therapy and again during a period of relapse. Neutropenia was not a feature of thes...

journal_title：Cancer

authors： Kitahara M,Kushner JP

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:The association of community factors and outcomes after hematopoietic cell transplantation (HCT) has not been comprehensively described. Using the County Health Rankings and Roadmaps (CHRR) and the Center for International Blood and Marrow Transplant Research (CIBMTR), this study evaluated the impact of comm...

journal_title：Cancer

authors： Hong S,Brazauskas R,Hebert KM,Ganguly S,Abdel-Azim H,Diaz MA,Beattie S,Ciurea SO,Szwajcer D,Badawy SM,Gratwohl AA,LeMaistre C,Aljurf MDSM,Olsson RF,Bhatt NS,Farhadfar N,Yared JA,Yoshimi A,Seo S,Gergis U,Beitinjane

更新日期：2021-02-15 00:00:00

abstract：BACKGROUND:The purpose of the study was to determine the utility of quantitation of the extracellular domain (ECD) of the HER-2/neu receptor in the serum for predicting response to treatment in patients with primary breast cancer receiving neoadjuvant therapy. METHODS:HER-2/neu ECD was measured in sera obtained from 3...

journal_title：Cancer

authors： Mazouni C,Hall A,Broglio K,Fritsche H,Andre F,Esteva FJ,Hortobagyi GN,Buzdar AU,Pusztai L,Cristofanilli M

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:The authors sought to determine whether differences existed in patterns of outcome and morbidity between the 3 thigh compartments after limb-sparing surgery and postoperative radiation therapy (RT). METHODS:A total of 255 patients with primary soft tissue sarcoma (STS) of the thigh were identified in our sa...

journal_title：Cancer

authors： Rimner A,Brennan MF,Zhang Z,Singer S,Alektiar KM

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:The current study determined the efficacy and toxicity of weekly paclitaxel in combination with estramustine phosphate (EMP) in patients with androgen-independent prostate carcinoma (AIPC). METHODS:Patients with progressive AIPC received 90 mg/m2 paclitaxel by 1-hour intravenous infusion weekly for 3 weeks,...

journal_title：Cancer

authors： Vaughn DJ,Brown AW Jr,Harker WG,Huh S,Miller L,Rinaldi D,Kabbinavar F

更新日期：2004-02-15 00:00:00