Immunologic evaluation of patients with advanced head and neck cancer receiving weekly chemoimmunotherapy.

abstract：:The diagnosis of malignant melanoma is based on clinical grounds and a properly performed biopsy, preferably excision, so that the type of melanoma and the thickness can be assessed by methods described by Clark and Breslow. These facilitate clinical and pathologic staging. Excisions with conservative margins for thin...

journal_title：Cancer

authors： Harris MN,Shapiro RL,Roses DF

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:Based on previous data demonstrating a potentially synergistic interaction between tamoxifen and cisplatin in metastatic melanoma therapy, a Phase II study was performed to assess the activity of tamoxifen, etoposide, mitoxantrone, and cisplatin (TEMP) in patients with metastatic breast carcinoma. METHODS:F...

journal_title：Cancer

authors： Conzen SD,Kaufman PA,Arvizu C,LeMarbre P,Maurer LH,Mott LA,Mills LE

更新日期：1996-11-01 00:00:00

abstract：:Gynecologic cancers present unusual opportunities to explore the fruits of well-designed clinical trials to assess the value of existing treatment using a combined modality approach soon after diagnosis. Cancers of the ovary and uterus have well-defined, familiar natural histories. Pathways of spread are clear and rea...

journal_title：Cancer

authors： DeVita VT Jr,Wasserman TH,Young RC,Carter SK

更新日期：1976-07-01 00:00:00

abstract：BACKGROUND:Although ascites cytology is important for therapeutic strategies, it is difficult to distinguish cancer infiltration from reactive mesothelial proliferation in some patients. In this study, the authors applied CDX2 immunocytochemistry to improve diagnostic accuracy. METHODS:The authors examined the distrib...

journal_title：Cancer

authors： Kobayashi M,Ueyama Y,Nakanishi H,Ishida H,Takahashi E,Nakamura S,Koshikawa T,Yatabe Y

更新日期：2006-04-25 00:00:00

abstract：:The effect of cis-diamminedichloroplatinum II (DDP) and ionizing radiation on human bladder transitional cell carcinoma (TCC) was evaluated in nude mouse-grown human tumors following administration of single-agent and combination treatment. Combination of DDP and radiation resulted in accelerated tumor regression and ...

journal_title：Cancer

authors： Kyriazis AP,Yagoda A,Kereiakes JG,Kyriazis AA,Whitmore WF Jr

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Testing for oral high-risk human papillomavirus (HPV) DNA may be useful for identifying individuals at increased risk for HPV-driven oropharyngeal cancer (OPC). However, positivity for HPV DNA provides no information on the transforming potential of the infection. In contrast, the detection of high-risk HPV ...

journal_title：Cancer

authors： Rollo F,Pichi B,Benevolo M,Giuliani M,Latini A,Lorenzon L,Colafigli M,Frasca M,Pellini R,Cristaudo A,Donà MG

更新日期：2019-08-01 00:00:00

abstract：:Four cases of non-Hodgkin's lymphoma (NHL) limited to the larynx are described. All were diffuse, high-grade, B-cell lymphomas of large lymphoid cell type (three centroblastic and one immunoblastic). Immunocytochemistry was performed on three cases; two showed monoclonal cytoplasmic immunoglobulin and one showed monoc...

journal_title：Cancer

authors： Morgan K,MacLennan KA,Narula A,Bradley PJ,Morgan DA

更新日期：1989-09-01 00:00:00

abstract：BACKGROUND:Although p53 and HER-2/neu overexpression are found in 30% of breast carcinomas in women of all ages and are associated with high rates of lymph node metastases, their role in women age < 30 years has not been studied extensively. METHODS:The institutional breast cancer data base was searched to identify yo...

journal_title：Cancer

authors： Maru D,Middleton LP,Wang S,Valero V,Sahin A

更新日期：2005-03-01 00:00:00

abstract：BACKGROUND:While the question of whether the trials of breast cancer screening have resulted in a reduction in breast cancer death has been the subject of much scrutiny, there has been less attention to the reduction in tumor size achieved by screening. METHODS:Size data for invasive breast tumors were assembled from ...

journal_title：Cancer

authors： Michaelson JS,Satija S,Kopans D,Moore R,Silverstein M,Comegno A,Hughes K,Taghian A,Powell S,Smith B

更新日期：2003-11-15 00:00:00

abstract：LAY SUMMARY:During the coronavirus disease 2019 (COVID-19) pandemic, cancer screening decreased precipitously; home screening for colorectal cancer diminished less than that for colonoscopy and breast and cervical cancer screening. The authors have highlighted approaches for home cancer screening in addition to telemed...

journal_title：Cancer

authors： Gorin SNS,Jimbo M,Heizelman R,Harmes KM,Harper DM

更新日期：2021-02-15 00:00:00

abstract：:Flow cytometry examinations (FCM) were carried out on 110 bladder irrigation specimens from 84 urologic outpatients who had had prior conservative treatment for low stage bladder tumors. The specimens were easily obtained, and adequately cellular in all cases. Of 60 examinations on patients with no cytoscopic abnormal...

journal_title：Cancer

authors： Devonec M,Darzynkiewicz Z,Kostyrka-Claps ML,Collste L,Whitmore WF Jr,Melamed MR

更新日期：1982-01-01 00:00:00

abstract：:Whether malignant cells can be detected in the bowel movements induced by oral gut lavage solution administration was studied in patients with known colonic adenocarcinomas. The induced bowel movements were collected in 27 patients, nine of whom had cancer proven by anatomic pathologic examination. The cells present w...

journal_title：Cancer

authors： Gordon IL,Rypins EB,Wuerker RB,Jakowatz JJ

更新日期：1991-07-01 00:00:00

abstract：:Fifty patients with metastatic breast cancer were treated with a combination of vincristine, Adriamycin and prednisolone (VAP) at four weekly intervals. Response rates of 78% for soft tissue disease, 66% for parenchymal lung disease, 67% for liver disease, and 64% for pleural effusions were seen. Only 26% of patients ...

journal_title：Cancer

authors： Russell JA,Baker JW,Dady PJ,Ford HT,Gazet JC,McKinna JA,Nash AG,Powles TJ

更新日期：1978-02-01 00:00:00

abstract：:Among the patients showing evidence of cerebral metastases without previously known cancer history, lung cancer has been found 37 times as the primary tumor in our institution. There were 34 men and three women and all but two were heavy smokers. Only one presented at diagnosis with thoracic symptoms but the chest rad...

journal_title：Cancer

authors： Trillet V,Catajar JF,Croisile B,Turjman F,Aimard G,Bourrat C,Bret P,Carrie C,Chassard JL,Chauvin F

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:The mortality of patients with colorectal carcinoma depends mainly upon subsequent liver metastasis even after curative operation. However, it is very difficult to predict the incidence of liver metastasis by analyzing conventional tumor markers or pathologic findings. In the current study, the authors exami...

journal_title：Cancer

authors： Kato M,Ito Y,Kobayashi S,Isono K

更新日期：1996-04-15 00:00:00

abstract：:Twenty-three adult patients (ages greater than 15 years) and 75 children with acute lymphoblastic leukemia were treated with similar intensive, sequential cytotoxic protocols (L-2). The adult patients have lower remission rate (78%) than the children (98%). The duration of remission and the length of survival are also...

journal_title：Cancer

authors： Gee TS,Haghbin M,Dowling MD,Cunningham I,Middleman MP,Clarkson BD

更新日期：1976-03-01 00:00:00

abstract：:Twenty-three bilateral testicular germ cell tumors (four synchronous and 19 sequential tumors) were investigated for potential risk factors. The incidence of maldescensus testis was not found to be higher than in patients with unilateral disease. The histologic findings of the first tumor did not have any effect on th...

journal_title：Cancer

authors： Kratzik C,Aiginger P,Kuber W,Riccabona M,Kührer I,Joos H,Frick J,Amann G,Mayr W

更新日期：1991-08-15 00:00:00

abstract：:There were no significant differences between the mean blood plasma (leukocyte-free) RNAase activity among 128 healthy women volunteers age 13-70 and 49 women with benign gynecological tumors. Exceptions to this finding were three apparently healthy women volunteers who had plasma enzyme activity which was higher than...

journal_title：Cancer

authors： Sheid B,Lu T,Pedrinan L,Nelson JH Jr

更新日期：1977-05-01 00:00:00

abstract：:Chromosome abnormalities from 17 malignancies that were studied using direct preparations and G-, Q-, and C-banding methods are presented and the findings assessed. The material used was from 6 primary cervical carcinomas, 5 primary and metastatic ovarian carcinomas and 6 other metastatic carcinomas. In general, chrom...

journal_title：Cancer

authors： van der Riet-Fox MF,Retief AE,van Niekerk WA

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND:Well differentiated (WD) and dedifferentiated (DD) retroperitoneal liposarcoma (RPLS) have distinct biologic behaviors. Consequently, the therapeutic approaches for these tumors differ and mandate an accurate preoperative diagnosis. The authors of this report evaluated whether computed tomography (CT) can be...

journal_title：Cancer

authors： Lahat G,Madewell JE,Anaya DA,Qiao W,Tuvin D,Benjamin RS,Lev DC,Pollock RE

更新日期：2009-03-01 00:00:00

abstract：BACKGROUND:Topoisomerase I inhibitors, like topotecan, have activity in myelodysplastic syndrome (MDS) and chronic myelomonocytic leukemia (CMML). 9-Nitro-camptothecin (9-NC) is a new oral topoisomerase inhibitor with a good safety profile. The aims of the current study were to evaluate the activity and safety of 9-NC ...

journal_title：Cancer

authors： Quintas-Cardama A,Kantarjian H,O'Brien S,Jabbour E,Giles F,Ravandi F,Faderl S,Pierce S,Shan J,Verstovsek S,Cortes J

更新日期：2006-10-01 00:00:00

abstract：:A case of primary hemangiosarcoma of the spleen in a 48-year-old woman is presented. Twenty-eight months after splenectomy the patient developed a severe anemia of the microangiopathic type, thrombocytopenia, and a leukoerythroblastic peripheral blood picture. In contrast to x-ray and conventional 99mTc-methylene-diph...

journal_title：Cancer

authors： Hermann GG,Fogh J,Graem N,Hansen OP,Hippe E

更新日期：1984-04-15 00:00:00

abstract：:Unnecessary, inappropriate, and futile care are given in all areas of health care including cancer care. Not only does such care increase costs and waste precious resources, but patients may have adverse outcomes when the wrong care is given. One of the ways to address this issue is to measure performance with the use...

journal_title：Cancer

authors： Lazar GS,Desch CE

更新日期：1998-05-15 00:00:00

abstract：BACKGROUND:The necessity to develop more effective chemotherapy regimens in advanced nonsmall cell lung carcinoma (NSCLC) prompted the authors to evaluate the paclitaxel-ifosfamide-cisplatin (PIC) combination, developed on the basis of high individual single-agent activity, in vitro synergism, and tolerance as determin...

journal_title：Cancer

authors： Kosmas C,Tsavaris NB,Polyzos A,Kalofonos HP,Sepsas E,Malamos NA,Vadiaka M,Dosios T,Antonopoulos MJ

更新日期：2000-08-15 00:00:00

abstract：BACKGROUND:Radiofrequency (RF)-induced tissue coagulation represents a new approach for the thermal destruction of tumors within the liver. The purpose of the current study was to 1) assess technique safety; 2) determine the extent and evolution of induced cellular damage; and 3) correlate the observed pathologic effec...

journal_title：Cancer

authors： Goldberg SN,Gazelle GS,Compton CC,Mueller PR,Tanabe KK

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Clinical guidelines recommend against routine prostate-specific antigen (PSA) screening for older men and for those with lower life expectancies. The authors of this report examined providers' decision-making regarding discontinuing PSA screening. METHODS:A survey of primary providers from a large, universi...

journal_title：Cancer

authors： Pollack CE,Platz EA,Bhavsar NA,Noronha G,Green GE,Chen S,Carter HB

更新日期：2012-11-15 00:00:00

abstract：BACKGROUND:There are several well known but rare syndromes of inherited colonic cancer. Genetic epidemiologic studies also have demonstrated that relatives of individuals with colonic cancer in general exhibit an excess risk for this malignancy. METHODS:This report reviews the literature pertinent to genetic and famil...

journal_title：Cancer

authors： Burt RW,Bishop DT,Cannon-Albright L,Samowitz WS,Lee RL,DiSario JA,Skolnick MH

更新日期：1992-09-15 00:00:00

abstract：BACKGROUND:Recently, the number and morphologic features of argyrophilic nucleolar organizer regions (AgNOR), silver-stained nucleolar organizer regions, were thought to reflect the cellular proliferative activity and the grade of malignancy. In liver diseases, it has been reported that AgNOR scores for hepatocellular ...

journal_title：Cancer

authors： Shiro T,Seki T,Naitoh Y,Inoue K,Okamura A

更新日期：1993-01-01 00:00:00

abstract：:Medical adrenalectomy, consisting of aminoglutethimide plus either dexamethasone or hydrocortisone, was administered to 53 women with advanced breast cancer. Sixteen (30%) patients had an objective response, five patients had stabilization of disease, 26 patients demonstrated progression of disease, two patients did n...

journal_title：Cancer

authors： Horsley JS 3rd,Newsome HH,Brown PW,Neifeld JP,Terz JJ,Lawrence W Jr

更新日期：1982-03-15 00:00:00

abstract：:Twenty of 391 newly diagnosed cases of prostatic cancer (5%) had a prior prostatectomy for benign disease. Digital rectal examination in 16 of 19 patients (84%) revealed a significant prostatic abnormality. Continued serial digital rectal examination should be performed routinely after prostatectomy for benign disease...

journal_title：Cancer

authors： Schwartz I,Wein AJ,Malloy TR,Glick JH

更新日期：1986-08-15 00:00:00