Metastasis to the thyroid gland. A report of 43 cases.

abstract：:The cell differentiation properties of two undifferentiated (embryonal) sarcomas of the liver (USL), one in a 9-year-old boy and one in a 23-year-old man, were studied by immunohistochemistry and electron microscopic examination. Both tumors showed a part pleomorphic pattern and a part myxoid spindle cell sarcomatous ...

journal_title：Cancer

authors： Miettinen M,Kahlos T

更新日期：1989-11-15 00:00:00

abstract：:Three bleomycin-resistant (BLMr) human carcinoma cell lines (HeLa-BLMr, KB-BLMr, and Hepd-uvBLMr) were established in culture by progressively increasing the concentration of bleomycin (BLM). HeLa-BLMr and KB-BLMr were obtained after 5 and 2 months of incubation with BLM, whereas the establishment of Hepd-uvBLMr requi...

journal_title：Cancer

authors： Urade M,Sugi M,Miyazaki T

更新日期：1988-04-15 00:00:00

abstract：BACKGROUND:Previous biochemotherapy regimens for metastatic melanoma have required attenuated dosages of interleukin 2 (IL-2) that may have compromised efficacy. METHODS:In a phase 2 study, the authors tested sequential temozolomide (75 mg/m2 per day orally for 3 weeks) followed by high-dose, IL-2 (600,000 U/kg per do...

journal_title：Cancer

authors： Tarhini AA,Kirkwood JM,Gooding WE,Moschos S,Agarwala SS

更新日期：2008-10-01 00:00:00

abstract：:Surgery is the most effective treatment for thyroid cancer; however, in some subsets of patients, the role of radiotherapy (RT) is important. The main indication for external-beam RT is incomplete surgery. When neoplastic tissue is left behind at operation, RT must be considered, but only if an experienced surgeon fee...

journal_title：Cancer

authors： Tubiana M,Haddad E,Schlumberger M,Hill C,Rougier P,Sarrazin D

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:The objective of this article was to assess the clinimetric properties of the International Federation of Gynecology and Obstetrics (FIGO) staging system of cervical carcinoma to determine whether it is an adequate prognostic tool for the survival of patients with cervical carcinoma. METHODS:The FIGO stagin...

journal_title：Cancer

authors： Kupets R,Covens A

更新日期：2001-08-15 00:00:00

abstract：BACKGROUND AND METHODS:Predictors of distant relapse following conservative surgery for breast cancer were studied in a review of 425 women. Five steps of breast cancer patient management were defined in which increasing amounts of information, potentially relevant to prognosis for metastasis-free survival (MFS), were ...

journal_title：Cancer

authors： Tubiana-Hulin M,Le Doussal V,Hacene K,Rouëssé J,Brunet M

更新日期：1993-08-15 00:00:00

abstract：BACKGROUND:The authors assessed the prognostic significance of abnormal cyclin dependent kinase inhibitor (CDKI) expression in adenocarcinomas of the uterine cervix. METHODS:Population-based, archival material from patients with International Federation of Gynecology and Obstetrics (FIGO) Stage I and II cervical adeno...

journal_title：Cancer

authors： Alfsen GC,Reed W,Sandstad B,Kristensen GB,Abeler VM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The optimal treatment of the primary tumor in patients with brain metastases (BM) from newly diagnosed nonsmall cell lung cancer (NSCLC) remains unclear. The authors aimed to identify patient groups with synchronous BM for whom radical treatment of the primary site may be appropriate. METHODS:The medical re...

journal_title：Cancer

authors： Lind JS,Lagerwaard FJ,Smit EF,Postmus PE,Slotman BJ,Senan S

更新日期：2011-02-01 00:00:00

abstract：:Lobular carcinoma may arise within the epithelial component of fibroadenoma of the breast, as evidenced by 5 cases reported from the files of the Mayo Clinic and 21 cases cited in the literature. The 5 cases reported here occurred in a series of 4000 cases of fibroadenoma during a 43-year period. Lobular carcinoma is ...

journal_title：Cancer

authors： Buzanowski-Konakry K,Harrison EG Jr,Payne WS

更新日期：1975-02-01 00:00:00

abstract：BACKGROUND:Cancer patients and their oncologists often report differing perceptions of consultation discussions and discordant expectations regarding treatment outcomes. CONNECT, a computer-based communication aid, was developed to improve communication between patients and oncologists. METHODS:CONNECT includes assess...

journal_title：Cancer

authors： Meropol NJ,Egleston BL,Buzaglo JS,Balshem A,Benson AB 3rd,Cegala DJ,Cohen RB,Collins M,Diefenbach MA,Miller SM,Fleisher L,Millard JL,Ross EA,Schulman KA,Silver A,Slater E,Solarino N,Sulmasy DP,Trinastic J,Weinfurt K

更新日期：2013-04-01 00:00:00

abstract：:The Southwest Oncology Group in a prospective randomized study compared one year of adjuvant combination chemotherapy with continuous CMFVP to two years of intermittent L-PAM in women with operable breast cancer with histologically positive axillary lymph nodes. In fully evaluable patients with a 42-month median and 3...

journal_title：Cancer

authors： Glucksberg H,Rivkin SE,Rasmussen S,Tranum B,Gad-el-Mawla N,Costanzi J,Hoogstraten B,Athens J,Maloney T,McCracken J,Vaughn C

更新日期：1982-08-01 00:00:00

abstract：:The experience of 260 patients with endometrial carcinoma was reviewed. The influence of factors such as age, stage of disease, grade and degree of myometrial penetration on the survival was presented, showing that survival decreases in elderly patients, in patients with advanced stage of disease, when the tumor is un...

journal_title：Cancer

authors： Tavares MA,Patricio MB,Vilhena M,Da Silva JN

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:9-Aminocamptothecin (9AC) and its parent compound, camptothecin, have shown outstanding preclinical activity against colorectal carcinoma. Irinotecan (CPT-11), another camptothecin derivative, has demonstrated clinical activity in patients with 5-fluorouracil (5-FU)-refractory colorectal carcinoma. METHODS:...

journal_title：Cancer

authors： Saltz LB,Kemeny NE,Tong W,Harrison J,Berkery R,Kelsen DP

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:The role of adjuvant therapy in the management of patients with malignant mixed Müllerian tumors (MMMT) of the uterus has not been defined. The outcome of planned multimodality therapy for patients with apparent early stage disease was assessed. METHODS:A pilot study was performed on 38 patients with clinic...

journal_title：Cancer

authors： Manolitsas TP,Wain GV,Williams KE,Freidlander M,Hacker NF

更新日期：2001-04-15 00:00:00

abstract：BACKGROUND:Plasma acidic glutathione S-transferase (GST-pi) concentrations in 135 patients with gastrointestinal cancer were measured by an improved radioimmunoassay (RIA). METHODS:Blood was collected into a silicified glass tube containing a specific anticoagulant. The plasma, which was separated rapidly by centrifug...

journal_title：Cancer

authors： Fan KC,Huang YC,Li CH

更新日期：1995-10-15 00:00:00

abstract：BACKGROUND:Several studies have shown that lysophosphatidic acid (LPA), a phospholipidic chemical mediator, is relevant to the pathogenesis of ovarian carcinoma. Higher plasma levels of LPA have been reported in patients with ovarian carcinoma than in healthy patients, and LPA is known to activate ovarian carcinoma cel...

journal_title：Cancer

authors： Tokumura A,Tominaga K,Yasuda K,Kanzaki H,Kogure K,Fukuzawa K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:The development of novel therapeutic approaches for cancer therapy is important, especially for tumors that have poor response or develop resistance to standard chemotherapy and radiation. We discovered that noninvasive radiofrequency (RF) fields can affect cancer cells but not normal cells, inhibit progress...

journal_title：Cancer

authors： Curley SA,Palalon F,Lu X,Koshkina NV

更新日期：2014-11-01 00:00:00

abstract：:Cancer is among the leading causes of morbidity and mortality in the Western world. Despite recent advances, most therapeutic approaches fail to eradicate the entire neoplastic clone. The remaining cells often develop metastasis and/or recurrences and therefore may represent attractive targets of therapy. A new exciti...

journal_title：Cancer

authors： Schulenburg A,Ulrich-Pur H,Thurnher D,Erovic B,Florian S,Sperr WR,Kalhs P,Marian B,Wrba F,Zielinski CC,Valent P

更新日期：2006-11-15 00:00:00

abstract：:Forty-four patients with advanced carcinoma of the head and neck were treated with cyclophosphamide, 400 mg/m2 plus BCNU, 100 mg/m2 day 1 followed by adriamycin 40 mg/m2 day 2, with therapy repeated every 4 weeks. Of 31 evaluable patients, there were 1 complete response, and 10 partial responses (35%). Four of 8 patie...

journal_title：Cancer

authors： Presant CA,Ratkin G,Klahr C,Brown C

更新日期：1979-11-01 00:00:00

abstract：:Several decades ago, it was reported that normal and malignant mesothelial cells were transformed into distinct cell types (epithelial to fibrous and fibrous to epithelial) when transferred to in vitro conditions. Those tissue culture data are still cited as evidence supporting that the mesothelial cell has multipoten...

journal_title：Cancer

authors： Suzuki Y,Chahinian AP,Ohnuma T

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate the long-term outcomes in patients with stage IE and IIE mucosa-associated lymphoid tissue (MALT) lymphomas treated with involved field radiotherapy (RT). METHODS:Between 1989 and 2004, 192 patients with stage I and II MALT lymphomas were treated. The report focuses on 1...

journal_title：Cancer

authors： Goda JS,Gospodarowicz M,Pintilie M,Wells W,Hodgson DC,Sun A,Crump M,Tsang RW

更新日期：2010-08-15 00:00:00

abstract：BACKGROUND:Methotrexate is readily absorbed from the intestinal tract. When given to patients with urinary diversion to the intestinal tract, methotrexate may be reabsorbed into the circulation, thus increasing its serum concentration and potentially increasing its toxicity. METHODS:Forty-eight patients with transitio...

journal_title：Cancer

authors： Srinivas S,Mahalati K,Freiha FS

更新日期：1998-03-15 00:00:00

abstract：:A case report is presented, believed to be the first documented example of pleomorphic rhabdomyosarcoma developing in the larynx of a child. A review of the literature then follows, with evaluation of the epidemiology, treatment options, and survival of patients with this disease. Cure of this malignancy is more likel...

journal_title：Cancer

authors： Dodd-o JM,Wieneke KF,Rosman PM

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Patients with familial adenomatous polyposis develop periampullary adenomas at a high rate. However, little is known regarding the factors that control the growth, the natural history, or the malignant potential of these tumors. METHODS:In this study, the authors systematically evaluated the expression of t...

journal_title：Cancer

authors： Resnick MB,Gallinger S,Wang HH,Odze RD

更新日期：1995-07-15 00:00:00

abstract：BACKGROUND:Because the prostatic capsule is often indistinct, recognition of extraprostatic extension by carcinoma depends heavily on the identification of carcinoma cells in the periprostatic adipose tissue. However, the distribution of adipose tissue along the prostatic surfaces has not been studied extensively. MET...

journal_title：Cancer

authors： Hong H,Koch MO,Foster RS,Bihrle R,Gardner TA,Fyffe J,Ulbright TM,Eble JN,Cheng L

更新日期：2003-04-01 00:00:00

abstract：BACKGROUND:Tamoxifen and aminoglutethimide are two hormone therapies reported to be effective palliative approaches for patients with metastatic breast cancer. The current trial was designed to evaluate their relative therapeutic effectiveness. METHODS:Two hundred forty-nine postmenopausal women with advanced breast c...

journal_title：Cancer

authors： Gale KE,Andersen JW,Tormey DC,Mansour EG,Davis TE,Horton J,Wolter JM,Smith TJ,Cummings FJ

更新日期：1994-01-15 00:00:00

abstract：:The squamous cell carcinoma (SCC) antigen was determined by radioimmunoassay in the serum of 40 untreated patients with SCC of the oromaxillofacial region. The mean (+/- SEM) serum concentration for these patients (3.8 +/- 0.8 ng/ml) was significantly higher than that of 52 disease-free patients coming to routine post...

journal_title：Cancer

authors： Fischbach W,Meyer T,Barthel K

更新日期：1990-03-15 00:00:00

abstract：BACKGROUND:Virilizing adrenocortical tumors are uncommon in adult women. These lesions generally secrete dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS), but not testosterone, which usually is produced by ovarian tumors. Exceptionally, adrenal growths may give off testosterone and no other asse...

journal_title：Cancer

authors： Del Gaudio AD,Del Gaudio GA

更新日期：1993-09-15 00:00:00

abstract：:A possible association between gallstones, colorectal cancer, and gastric cancer was investigated. The age distribution and mean age of the two cancer groups were identical. The incidence of gallstones in 378 colorectal cancer cases and 869 gastric cancer cases was 7.1% and 5.5%, respectively. Of colorectal cancer cas...

journal_title：Cancer

authors： Narisawa T,Yamazaki Y,Kusaka H,Takahashi M,Kotanagi H,Koyama K

更新日期：1991-03-15 00:00:00

abstract：:A 21-year-old patient, after radiation therapy to the mediastinum for Hodgkin's disease, died six years later of a spinal cord glioma, believed to be caused by irradiation therapy. That the x-ray therapy provoked neoplastic changes seems likely, although it could be coincidental. ...

journal_title：Cancer

authors： Clifton MD,Amromin GD,Perry MC,Abadir R,Watts C,Levy N

更新日期：1980-04-15 00:00:00