New strategies are needed in diffuse malignant mesothelioma.

abstract：:The relationship between DNA content, clinicopathologic findings, and patient survival in synovial sarcoma was investigated. Patient age at diagnosis (P less than 0.001), tumor size (P less than 0.001), and ploidy status (P less than 0.003) correlated significantly with patient survival. A marginally significant corre...

journal_title：Cancer

authors： el-Naggar AK,Ayala AG,Abdul-Karim FW,McLemore D,Ballance WW,Garnsey L,Ro JY,Batsakis JG

更新日期：1990-05-15 00:00:00

abstract：BACKGROUND:The health-related functioning of patients with cancer is compromised by several factors, including the disease process, treatment, and the various symptoms that are produced by both disease and treatment. This study was designed to specify the relationship between patients' pain severity and their self-repo...

journal_title：Cancer

authors： Wang XS,Cleeland CS,Mendoza TR,Engstrom MC,Liu S,Xu G,Hao X,Wang Y,Ren XS

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Adenosquamous/squamous cell carcinoma of the gallbladder generally has been considered a lethal disease. The objective of this study was to clarify the effectiveness of resection for patients with adenosquamous/squamous cell carcinoma of the gallbladder. METHODS:Twenty-nine patients who underwent resection ...

journal_title：Cancer

authors： Oohashi Y,Shirai Y,Wakai T,Nagakura S,Watanabe H,Hatakeyama K

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND:Optic pathway gliomas (OPGs) are commonly noted in pediatric oncology services. Radiotherapy is effective at controlling tumors, but has many undesirable late effects, especially in patients with neurofibromatosis. Chemotherapy is commonly used to preserve vision and delay or eliminate the need for radiother...

journal_title：Cancer

authors： Dodgshun AJ,Elder JE,Hansford JR,Sullivan MJ

更新日期：2015-12-01 00:00:00

abstract：:The authors describe a new technique for the subcutaneous heterotopic transplantation of the ovary before pelvic irradiation to treat Hodgkin's disease. Creation of a cavity to receive the transplant and the use of two surgical teams and the surgical microscope during the operation ensured its successful outcome. The ...

journal_title：Cancer

authors： Leporrier M,von Theobald P,Roffe JL,Muller G

更新日期：1987-11-01 00:00:00

abstract：:Chromosome abnormalities from 17 malignancies that were studied using direct preparations and G-, Q-, and C-banding methods are presented and the findings assessed. The material used was from 6 primary cervical carcinomas, 5 primary and metastatic ovarian carcinomas and 6 other metastatic carcinomas. In general, chrom...

journal_title：Cancer

authors： van der Riet-Fox MF,Retief AE,van Niekerk WA

更新日期：1979-12-01 00:00:00

abstract：:The case of a 49-year-old man with the diagnosis of angioimmunoblastic lymphadenopathy is reported. The patient survived a stormy clinical course. The corticosteroids improved dramatically the clinical picture although the patient developed a staphylococcal septicemia. Before treatment immunological studies were done ...

journal_title：Cancer

authors： Kosmidis PA,Axelrod AR,Palacas C,Stahl M

更新日期：1978-08-01 00:00:00

abstract：BACKGROUND:Apricoxib, a novel once-daily selective cyclooxygenase-2 inhibitor, was investigated in combination with erlotinib for recurrent stage IIIB/IV nonsmall cell lung cancer to determine the maximum tolerated dose, dose-limiting toxicity, and recommended phase II dose (RP2D) based on changes in urinary prostaglan...

journal_title：Cancer

authors： Reckamp K,Gitlitz B,Chen LC,Patel R,Milne G,Syto M,Jezior D,Zaknoen S

更新日期：2011-02-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to assess prostate carcinoma detection and discrimination of benign from malignant prostate tissue with contrast-enhanced ultrasonography. METHODS:In all, 301 subjects referred for prostate biopsy were evaluated with contrast-enhanced sonography using continuous harmonic imagin...

journal_title：Cancer

authors： Halpern EJ,Ramey JR,Strup SE,Frauscher F,McCue P,Gomella LG

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Patients' estimates of their chances of therapeutic benefit from participation in early phase trials greatly exceed historical data. Ethicists worry that this therapeutic misestimation undermines the validity of informed consent. METHODS:The authors interviewed 45 patients enrolled in phase 1 or 2 oncology ...

journal_title：Cancer

authors： Sulmasy DP,Astrow AB,He MK,Seils DM,Meropol NJ,Micco E,Weinfurt KP

更新日期：2010-08-01 00:00:00

abstract：BACKGROUND:Polyunsaturated n-3 fatty acids have been shown to inhibit the growth and metastasis of tumors. This double-blind, randomized study was designed to evaluate the hypothesis that polyunsaturated n-3 fatty acids can improve metabolic parameters, decrease chemical indices of inflammation, enhance quality of life...

journal_title：Cancer

authors： Ogilvie GK,Fettman MJ,Mallinckrodt CH,Walton JA,Hansen RA,Davenport DJ,Gross KL,Richardson KL,Rogers Q,Hand MS

更新日期：2000-04-15 00:00:00

abstract：BACKGROUND:The reliability of fine-needle aspiration cytology (FNAC) of breast masses in males could be compromised by lack of experience because breast carcinoma is rare in males and FNAC is not often used. In addition, FNAC of the more often encountered gynecomastia may lead to overdiagnosis. Therefore, in the curren...

journal_title：Cancer

authors： Westenend PJ,Jobse C

更新日期：2002-04-25 00:00:00

abstract：BACKGROUND:Aprotinin has been used to decrease blood loss with complicated cardiac surgery but has not been investigated in extrapleural pneumonectomy, an operation that does not use cardiopulmonary bypass. In this prospective, randomized, placebo-controlled, double-blind trial, the authors investigated whether aprotin...

journal_title：Cancer

authors： Norman PH,Thall PF,Purugganan RV,Riedel BJ,Thakar DR,Rice DC,Huynh L,Qiao W,Wen S,Smythe WR

更新日期：2009-02-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the rate and possible reasons for false-negative (FN) reflex human papillomavirus (HPV)-DNA tests. METHODS:The authors reviewed all ThinPrep cervical specimens that were submitted for reflex HPV-DNA testing using the Digene Hybrid Capture II (HC2) method from Januar...

journal_title：Cancer

authors： Eltoum IA,Chhieng DC,Crowe DR,Roberson J,Jin G,Broker TR

更新日期：2007-06-25 00:00:00

abstract：BACKGROUND:There is an increase in the incidence of cutaneous malignant melanoma (CMM) among white people throughout the world. In Sweden, a fivefold increase has been recorded since 1960, but the mortality is rising at a much lower rate. Tumor thickness is the single most important prognostic factor for primary melano...

journal_title：Cancer

authors： Måsbäck A,Westerdahl J,Ingvar C,Olsson H,Jonsson N

更新日期：1994-03-15 00:00:00

abstract：BACKGROUND:Patients with hereditary leiomyomatosis and renal cell carcinoma (HLRCC) resulting from fumarate hydratase (FH) mutations may present with skin, uterine, and renal tumors, with each having unique pathologic features. This study investigated the association between prospectively identified suspicious patholog...

journal_title：Cancer

authors： Kopp RP,Stratton KL,Glogowski E,Schrader KA,Rau-Murthy R,Russo P,Coleman JA,Offit K

更新日期：2017-07-01 00:00:00

abstract：:The predisposition of preexisting cirrhotic metabolic liver disease to the development of hepatocellular carcinoma is well established. However, the association between glycogenoses (a form of noncirrhotic metabolic liver disease) and the formation of benign and malignant liver tumors is less well known. The sixth cas...

journal_title：Cancer

authors： Conti JA,Kemeny N

更新日期：1992-03-15 00:00:00

abstract：BACKGROUND:During hospitalization for hematopoietic stem cell transplantation (HCT), patients experience a steep deterioration in quality of life (QOL) and mood. To our knowledge, the impact of this deterioration on patients' QOL and posttraumatic stress disorder (PTSD) symptoms after HCT is unknown. METHODS:We conduc...

journal_title：Cancer

authors： El-Jawahri AR,Vandusen HB,Traeger LN,Fishbein JN,Keenan T,Gallagher ER,Greer JA,Pirl WF,Jackson VA,Spitzer TR,Chen YB,Temel JS

更新日期：2016-03-01 00:00:00

abstract：BACKGROUND:Lymph node involvement is an important prognostic factor in gallbladder carcinoma (GBC). The lymph node involvement pattern, extent, and indications for systematic lymph node dissection for patients with advanced GBC were investigated. METHODS:Forty-one patients with GBC who underwent radical resection with...

journal_title：Cancer

authors： Shimada H,Endo I,Togo S,Nakano A,Izumi T,Nakagawara G

更新日期：1997-03-01 00:00:00

abstract：:Exposure of tumor cells to reduced folates before or with the fluoropyrimidines, 5-fluorouracil or 5-fluoro-2'deoxyuridine, results in a substantial increase in the activity of these drugs. Available evidence suggests that the mechanism of this synergism is a kinetic stabilization of complex formed between thymidylate...

journal_title：Cancer

authors： Morgan RG

更新日期：1989-03-15 00:00:00

abstract：:A system for staging the clinical status of patients with soft tissue sarcomas is presented, based on the clinical characteristics of the primary tumor (size, extension), the involvement of lymph nodes, the presence of metastases, and the grade of the tumor. This represents the TNM system with grade of tumor (G) added...

journal_title：Cancer

authors： Russell WO,Cohen J,Enzinger F,Hajdu SI,Heise H,Martin RG,Meissner W,Miller WT,Schmitz RL,Suit HD

更新日期：1977-10-01 00:00:00

abstract：:A tumor that affects the central nervous system can have a dramatic impact on the individual affected, as well as his or her family and friends. The tumor, regardless of extent or location, may affect the physical, social, vocational, and emotional capabilities of the individual. Basic aspects of rehabilitation for pa...

journal_title：Cancer

authors： Kirshblum S,O'Dell MW,Ho C,Barr K

更新日期：2001-08-15 00:00:00

abstract：:Interleukin-6 (IL-6) plays a major role in the response to injury or infection and is involved in the immune response, inflammation, and hematopoiesis. Its deregulation impacts numerous disease states, including many types of cancer. Consequently, modulating IL-6 may be an innovative therapeutic strategy in several di...

journal_title：Cancer

authors： Hong DS,Angelo LS,Kurzrock R

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:The carboplatin-based chemotherapeutic regimen M-CAVI (methotrexate, carboplatin, and vinblastine) is active against bladder carcinoma and can be administered to patients who are ineligible to receive cisplatin or doxorubicin. The authors designed a randomized study to evaluate whether M-CAVI offers a therap...

journal_title：Cancer

authors： Bellmunt J,Ribas A,Eres N,Albanell J,Almanza C,Bermejo B,Solé LA,Baselga J

更新日期：1997-11-15 00:00:00

abstract：:Ewing's sarcoma is a small cell malignant tumor that usually arises in the medullary cavity of bone. Less frequently, it originates in soft tissue and may secondarily invade underlying bone. The origin of Ewing's sarcoma in a periosteal location without extension into either the bone or adjacent soft tissue has not be...

journal_title：Cancer

authors： Bator SM,Bauer TW,Marks KE,Norris DG

更新日期：1986-10-15 00:00:00

abstract：:The authors investigated the level of lipid peroxidation and possible related phenomena in the activation of phospholipase A2 and the infiltration of granulocyte neutrophils in human colorectal cancer tissue samples. Malondialdehyde (an index of lipid peroxidation), phospholipase A2 activity, and myeloperoxidase activ...

journal_title：Cancer

authors： Otamiri T,Sjödahl R

更新日期：1989-07-15 00:00:00

abstract：:The infiltration of dendritic cells determined in 210 patients with gastric carcinoma was investigated from the standpoint of tumor invasion, lymph node metastasis, and prognosis. Dendritic cell infiltration was graded as "slight" and "marked." The 39% frequency in the marked infiltration group at the mucosal stage di...

journal_title：Cancer

authors： Tsujitani S,Kakeji Y,Watanabe A,Kohnoe S,Maehara Y,Sugimachi K

更新日期：1990-11-01 00:00:00

abstract：:A 48-year-old male presented with the nephrotic syndrome 3 years after resection and irradiation of a thymoma. Renal biopsy revealed membranous glomerulonephritis by electron microscopy. IgA, IgG, and C3 deposition were present in the glomerular basement membrane by immunofluorescence. There was no evidence of other a...

journal_title：Cancer

authors： Posner MR,Prout MN,Berk S

更新日期：1980-01-15 00:00:00

abstract：:The treatment of locally advanced rectal cancer (LARC) has benefited from improved surgical techniques and from the implementation of neoadjuvant chemoradiotherapy (CRT), which have markedly decreased the rates of local recurrence. However, distant metastatic disease remains the most significant cause of death for the...

journal_title：Cancer

authors： Ludmir EB,Palta M,Willett CG,Czito BG

更新日期：2017-05-01 00:00:00

abstract：:Twenty-two patients seen between 1975 and 1988 were analyzed who had surgical attempts to cure locally advanced prostate cancer by exenterative procedures or salvage surgery for radiation recurrent disease. Twelve patients (Group I) underwent either a salvage cystoprostatectomy or perineal prostatectomy for radiorecur...

journal_title：Cancer

authors： Moul JW,Paulson DF

更新日期：1991-09-15 00:00:00