Increased lipid peroxidation in malignant tissues of patients with colorectal cancer.

Abstract:

:The authors investigated the level of lipid peroxidation and possible related phenomena in the activation of phospholipase A2 and the infiltration of granulocyte neutrophils in human colorectal cancer tissue samples. Malondialdehyde (an index of lipid peroxidation), phospholipase A2 activity, and myeloperoxidase activity (a marker of granulocyte neutrophils) were found to be increased significantly in cancerous compared with macroscopically normal tissues. They concluded that increased lipid peroxidation, phospholipase A2, and myeloperoxidase activity are associated with human colorectal cancer.

journal_name

Cancer

journal_title

Cancer

authors

Otamiri T,Sjödahl R

doi

10.1002/1097-0142(19890715)64:2<422::aid-cncr28206

subject

Has Abstract

pub_date

1989-07-15 00:00:00

pages

422-5

issue

2

eissn

0008-543X

issn

1097-0142

journal_volume

64

pub_type

杂志文章

相关文献

CANCER文献大全
  • The treatment of ejaculation disorders after retroperitoneal lymph node dissection.

    abstract::In 14 patients by bilateral retroperitoneal lymph node dissection for nonseminoma tumors of the testes, several sexual functions before and after node dissection were compared. All patients had normal sexual function before the operation. After the operation, antegrade ejaculation was found to have disappeared complet...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19821215)50:12<2967::aid-cncr282

    authors: Nijman JM,Jager S,Boer PW,Kremer J,Oldhoff J,Koops HS

    更新日期:1982-12-15 00:00:00

  • Sequential magnetic resonance imaging of cervical cancer: the predictive value of absolute tumor volume and regression ratio measured before, during, and after radiation therapy.

    abstract:BACKGROUND:The objectives of this study were to investigate outcome prediction by measuring absolute tumor volume and regression ratios using serial magnetic resonance imaging (MRI) during radiation therapy (RT) for cervical cancer and to develop algorithms capable of identifying patients at risk of a poor therapeutic ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25260

    authors: Wang JZ,Mayr NA,Zhang D,Li K,Grecula JC,Montebello JF,Lo SS,Yuh WT

    更新日期:2010-11-01 00:00:00

  • Splenic alterations in hairy-cell leukemia: II. an electron microscopic study.

    abstract::Spleen from nine patients with hairy-cell leukemia (HCL) were studied for ultrastructural alterations. In all cases, hairy cells with typical ultrastructural characteristics were observed within splenic cords and sinuses. Hairy cells had numerous cytoplasmic processes that interdigitated with cytoplasmic processes of ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820415)49:8<1617::aid-cncr2820

    authors: Pilon VA,Davey FR,Gordon GB,Jones DB

    更新日期:1982-04-15 00:00:00

  • Prognostic importance of histologic grading in papillary thyroid carcinoma.

    abstract:BACKGROUND:The influence of various clinicopathologic features on survival of patients with papillary thyroid carcinoma has been examined. In particular, histologic grade, which was obtained by a combined assessment of nuclear atypia, tumor necrosis, and vascular invasion (VAN score) was studied. According to this, his...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931101)72:9<2680::aid-cncr2820

    authors: Akslen LA

    更新日期:1993-11-01 00:00:00

  • Gemcitabine-associated thrombotic microangiopathy.

    abstract:BACKGROUND:Gemcitabine-associated thrombotic microangiopathy (TMA) is believed to be very rare, with an estimated incidence rate of 0.015%. Indications for gemcitabine are expanding, and comprehensive characterization of this complication is therefore important. METHODS:The authors performed a retrospective chart revi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20290

    authors: Humphreys BD,Sharman JP,Henderson JM,Clark JW,Marks PW,Rennke HG,Zhu AX,Magee CC

    更新日期:2004-06-15 00:00:00

  • Randomized controlled study of chemoimmunotherapy of acute myelogenous leukemia (AML) in adults with Nocardia rubra cell-wall skeleton and irradiated allogeneic AML cells.

    abstract::The effect of immunotherapy with Nocardia rubra cell-wall skeleton (N-CWS) on remission duration and survival of adults with acute myelogenous leukemia (AML) was studied in a prospective randomized controlled study. After having been induced into complete remission and having been consolidated, 73 patients were random...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(19860415)57:8<1483::aid-cncr2820

    authors: Ohno R,Nakamura H,Kodera Y,Ezaki K,Yokomaku S,Oguma S,Kubota Y,Shibata H,Ogawa N,Masaoka T

    更新日期:1986-04-15 00:00:00

  • Bladder cancer as seen in giant histologic sections.

    abstract::Giant sections from cystectomy specimens in 45 cases of bladder cancer were examined microscopically after en bloc fixation and processing. There were 35 transitional cell, seven squamous cell, and three mixed transitional cell and squamous carcinomas. Broad front invasion was associated with papillary and superficial...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197702)39:2<447::aid-cncr2820390

    authors: Soto EA,Friedell GH,Tiltman AJ

    更新日期:1977-02-01 00:00:00

  • Cancer-associated galactosyltransferase acceptor: inhibition of transformed cell and tumor growth.

    abstract::A distinctive glycopeptide, which acts as an acceptor for a cancer-associated galactosyltransferase, has been detected in sera and effusions of patients with extensive carcinoma. Cancer-associated galactosyltransferase acceptor (CAGA) purified from human malignant effusions was tested for its effects on cell growth in...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800315)45:5+<1212::aid-cncr282

    authors: Podolsky DK,Isselbacher KJ

    更新日期:1980-03-15 00:00:00

  • A centralized mailed program with stepped increases of support increases time in compliance with colorectal cancer screening guidelines over 5 years: A randomized trial.

    abstract:BACKGROUND:Screening over many years is required to optimize reductions in colorectal cancer (CRC) mortality. However, no prior trials have compared strategies for obtaining long-term adherence. METHODS:Systems of Support to Increase Colorectal Cancer Screening and Follow-Up was implemented in an integrated health car...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/cncr.30908

    authors: Green BB,Anderson ML,Cook AJ,Chubak J,Fuller S,Meenan RT,Vernon SW

    更新日期:2017-11-15 00:00:00

  • Spontaneous remission of recurring disseminated intravascular coagulation associated with prostatic carcinoma.

    abstract::A 58-year-old patient with metastatic prostatic carcinoma had two well-documented episodes of disseminated intravascular coagulation (DIC) occurring 1 year apart and resolving without heparin therapy. This case illustrates that DIC need not have a poor prognosis and may resolve spontaneously despite progressive cancer...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197602)37:2<928::aid-cncr2820370

    authors: Alving BM,Abeloff MD,Bell W

    更新日期:1976-02-01 00:00:00

  • In vivo metabolism of childhood posterior fossa tumors and primitive neuroectodermal tumors before and after treatment.

    abstract:BACKGROUND:Despite an increasing interest in the clinical application of positron emission tomography (PET) in tumors of the adult patient as a diagnostic and prognostic tool, only a few studies have been concerned with the usefulness of PET with [18F]2-deoxy-2-fluoro-D-glucose (FDG) in childhood tumors. METHODS:Fifte...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930815)72:4<1394::aid-cncr2820

    authors: Holthoff VA,Herholz K,Berthold F,Widemann B,Schröder R,Neubauer I,Heiss WD

    更新日期:1993-08-15 00:00:00

  • Prostatic acid phosphatase in strumal carcinoids of the ovary. An immunohistochemical study.

    abstract:BACKGROUND:Strumal carcinoids (SC) are ovarian tumors containing thyroid parenchyma admixed with carcinoid elements. Microscopically, the carcinoid component of SC usually presents a ribbon or trabecular pattern similar to the pattern exhibited by hindgut carcinoids. The authors designed an immunohistochemical study to...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930901)72:5<1673::aid-cncr2820

    authors: Sidhu J,Sánchez RL

    更新日期:1993-09-01 00:00:00

  • Histogenesis of Brenner tumors, I: histology and ultrastructure.

    abstract::The histology of 36 benign and four proliferative Brenner tumors is reviewed, and the ultrastructural features of benign Brenner tumors are described. Evidence is presented for the origin of these tumors from celomic inclusion cysts through transitional metaplasia of the cyst lining and progressive growth of branching...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19801215)46:12<2607::aid-cncr282

    authors: Shevchuk MM,Fenoglio CM,Richart RM

    更新日期:1980-12-15 00:00:00

  • Association between adherence to National Comprehensive Cancer Network treatment guidelines and improved survival in patients with colon cancer.

    abstract:BACKGROUND:The objective of the current study was to examine the impact of adherence to guidelines on stage-specific survival outcomes in patients with stage III and high-risk stage II colon cancer. The National Comprehensive Cancer Network (NCCN) has established working, expert consensus, and evidence-based guidelines...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.27935

    authors: Boland GM,Chang GJ,Haynes AB,Chiang YJ,Chagpar R,Xing Y,Hu CY,Feig BW,You YN,Cormier JN

    更新日期:2013-04-15 00:00:00

  • Inhibition of radiogenic mammary carcinoma in rats by estriol or tamoxifen.

    abstract::Mammary carcinomas have been induced by 3.5 Gy whole-body gamma radiation administered at age 40 to 50 days to virgin female Sprague-Dawley rats. In 142 irradiated controls carcinoma incidence averaged 7.8% in survivors observed less than 300 days and 38.3% of those surviving longer (P less than 0.001 by t test). Mamm...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900501)63:9<1685::aid-cncr2820

    authors: Lemon HM,Kumar PF,Peterson C,Rodriguez-Sierra JF,Abbo KM

    更新日期:1989-05-01 00:00:00

  • Primary linitis plastica of the colon: report of two cases and review of the literature.

    abstract::Two cases of primary linitis plastica of the large intestine will be presented and discussed. Characteristic clinical features of this type of adenocarcinoma of the large intestine include younger age of presentation, low incidence of hepatic metastasis and a high incidence of ovarian, lymph node and peritoneal metast...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197806)41:6<2420::aid-cncr282041

    authors: Amorn Y,Knight WA Jr

    更新日期:1978-06-01 00:00:00

  • Women age < or = 35 years with primary breast carcinoma: disease features at presentation.

    abstract:BACKGROUND:The purpose of the current study was to describe a population of young patients with breast carcinoma, their characteristics at the time of diagnosis, and the association of these characteristics with disease recurrence and survival. METHODS:Four hundred fifty-two women age < or = 35 years with breast carci...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21070

    authors: Gonzalez-Angulo AM,Broglio K,Kau SW,Eralp Y,Erlichman J,Valero V,Theriault R,Booser D,Buzdar AU,Hortobagyi GN,Arun B

    更新日期:2005-06-15 00:00:00

  • Mammography screening in African American women: evaluating the research.

    abstract:BACKGROUND:Notwithstanding some controversy regarding the benefits of screening mammography, it is generally assumed that the effects are the same for women of all race/ethnic groups. Yet evidence for its efficacy from clinical trial studies comes primarily from the study of white women. It is likely that mammography i...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.11022

    authors: Jones BA,Patterson EA,Calvocoressi L

    更新日期:2003-01-01 00:00:00

  • Multifocal osteosarcoma: a case report with review of the literature.

    abstract::Multifocal osteosarcoma with unique patho-biological features in a 23-year old white male is reported. The natural history and classification of multiple osteosarcomas are reviewed. A proposal is presented for evaluation of the multicentric origin in future cases. ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197911)44:5<1897::aid-cncr282044

    authors: Mahoney JP,Spanier SS,Morris JL

    更新日期:1979-11-01 00:00:00

  • K-ras mutations in incident sporadic colorectal adenomas.

    abstract:BACKGROUND:Although K-ras is the most frequently mutated protooncogene in colorectal carcinoma, the specific role and timing of K-ras mutations in colorectal carcinogenesis remains controversial. In the current study, the authors investigated associations with K-ras mutation in incident sporadic colorectal adenomas tha...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21721

    authors: Barry EL,Baron JA,Grau MV,Wallace K,Haile RW

    更新日期:2006-03-01 00:00:00

  • The role of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography in disseminated carcinoma of unknown primary site.

    abstract:BACKGROUND:The authors conducted a comprehensive review of the efficacy of 2-deoxy-2-[F-18]fluoro-D-glucose positron emission tomography (FDG-PET) in the detection of primary tumors in patients with disseminated carcinoma of unknown primary site. METHODS:Ten studies (involving a total of 221 patients) tat were publish...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.22410

    authors: Sève P,Billotey C,Broussolle C,Dumontet C,Mackey JR

    更新日期:2007-01-15 00:00:00

  • The sequential changes in DNA synthesis, glucose utilization, protein synthesis, and peripheral benzodiazepine receptor density in C6 brain tumors after chemotherapy to predict the response of tumors to chemotherapy.

    abstract:BACKGROUND:Monitoring therapy in patients with brain tumors is very difficult and unreliable. It has been shown that there is no good correlation between tumor sensitivity measured in vitro and in situ tumor response to therapies. METHODS:Sequential changes in tumor size, number of DNA synthesizing cells (labelling in...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19960315)77:6<1167::aid-cn

    authors: Takeda N,Diksic M,Yamamoto YL

    更新日期:1996-03-15 00:00:00

  • Human papillomavirus in cervical cancer and oropharyngeal cancer: One cause, two diseases.

    abstract::Human papillomavirus (HPV) causes greater than 5% of cancers worldwide, including all cervical cancers and an alarmingly increasing proportion of oropharyngeal cancers (OPCs). Despite markedly reduced cervical cancer incidence in industrialized nations with organized screening programs, cervical cancer remains the sec...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.30588

    authors: Berman TA,Schiller JT

    更新日期:2017-06-15 00:00:00

  • Plasma sex hormone binding globulin in patients with prostatic carcinoma.

    abstract::The concentrations of sex hormone binding globulin (SHBG) were measured in the plasma of 56 men, who were 47 to 85 years of age, by time-resolved immunofluorometric assay with a monoclonal antibody. Twenty-five of the men had untreated carcinoma of the prostate and 17 had untreated prostatic hyperplasia. There were 14...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19900715)66:2<354::aid-cncr28206

    authors: Grasso M,Buonaguidi A,Mondina R,Borsellino G,Lania C,Banfi G,Rigatti P

    更新日期:1990-07-15 00:00:00

  • The management of inferior vena cava obstruction complicating metastatic germ cell tumors.

    abstract:BACKGROUND:Inferior vena cava obstruction (IVCO) is a poorly characterized complication of metastatic germ cell tumor (GCT). The authors identified 31 cases to describe the clinical features, radiologic findings, complications, and treatment of this clinical entity. METHODS:Patients with GCT and IVCO were identified f...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Hassan B,Tung K,Weeks R,Mead GM

    更新日期:1999-02-15 00:00:00

  • Ultrasound-guided transcutaneous Tru-Cut biopsy to diagnose laryngopharyngeal masses: a pilot study.

    abstract:BACKGROUND:Patients with bulky laryngopharyngeal masses and a relative or absolute contraindication to general anesthesia present diagnostic difficulties. In the current study, the authors assessed the utility of transcutaneous ultrasound-guided Tru-Cut biopsy (USGTCB) under local anesthesia in such individuals. METHO...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22679

    authors: Ansarin M,De Fiori E,Preda L,Maffini F,Bruschini R,Calabrese L,Jereczek-Fossa BA,Chiesa F,Bellomi M

    更新日期:2007-06-01 00:00:00

  • Omental-mesenteric inflammatory pseudotumor. Cytogenetic demonstration of genetic changes and monoclonality in one tumor.

    abstract:BACKGROUND:Extrapulmonary inflammatory pseudotumor (plasma cell granuloma) is an uncommon lesion in adults and children, and little is known either of its etiology or clinical characteristics. However, it remains a significant source of morbidity to patients and confusion to clinicians. METHODS:Case reports are presen...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19940301)73:5<1433::aid-cncr2820

    authors: Treissman SP,Gillis DA,Lee CL,Giacomantonio M,Resch L

    更新日期:1994-03-01 00:00:00

  • X;6 translocation in a child with congenital acute lymphocytic leukemia.

    abstract::A case of congenital acute lymphoblastic leukemia (ALL) displayed an X;6 translocation. This is the third reported case of ALL with an X;6 translocation. In addition, two of the three ALL cases occurred during infancy, at ages 2 months and newborn, and both translocations involved the band q15-16 region of chromosome ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19920201)69:3<799::aid-cncr28206

    authors: Carney LA,Kinney JS,Higgins RR,Freeman AI,Hecht BK,Woods GM

    更新日期:1992-02-01 00:00:00

  • A retrospective study of 370 borderline tumors of the ovary treated at the Norwegian Radium Hospital from 1970 to 1982. A review of clinicopathologic features and treatment modalities.

    abstract:METHODS:Three-hundred seventy patients with borderline tumors treated between 1970 and 1982 at the Norwegian Radium Hospital were analyzed retrospectively for clinicopathologic features, treatment, and survival characteristics. RESULTS:One hundred seventy-eight patients had mucinous tumors, 174 patients had serous tum...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930301)71:5<1810::aid-cncr2820

    authors: Kaern J,Tropé CG,Abeler VM

    更新日期:1993-03-01 00:00:00

  • Cost-effectiveness of human papillomavirus vaccination for adolescent girls in Punjab state: Implications for India's universal immunization program.

    abstract:BACKGROUND:Introduction of human papillomavirus (HPV) vaccination for adolescent girls is being considered in the Punjab state of India. However, evidence regarding cost-effectiveness is sought by policy makers when making this decision. The current study was undertaken to evaluate the incremental cost per quality-adju...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30734

    authors: Prinja S,Bahuguna P,Faujdar DS,Jyani G,Srinivasan R,Ghoshal S,Suri V,Singh MP,Kumar R

    更新日期:2017-09-01 00:00:00