Inhibition of radiogenic mammary carcinoma in rats by estriol or tamoxifen.

abstract：:Dual tracer scintigraphy (DTS) (technetium 99m [99mTc] sulfur colloid and gallium 67 citrate [67 gallium citrate]) of the liver and computer subtraction studies (SS) were performed in 26 patients subsequently proven to have hepatocellular carcinoma (HCC) and 32 patients with cirrhosis and focal defects on the colloid ...

journal_title：Cancer

authors： Sostre S,Villagra D,Morales NE,Rivera JV

更新日期：1988-02-15 00:00:00

abstract：:A retrospective study of all cases of seminoma treated at Roswell Park Memorial Institute from 1970 through 1979 was conducted. Fifty-six evaluable patients treated initially with radiation therapy were seen during this period, and the overall survival rate at an average follow-up period of 52 months was 82%. The surv...

journal_title：Cancer

authors： Huben RP,Williams PD,Pontes JE,Panahon AM,Murphy GP

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND:BRAF inhibitors are effective in melanoma and other cancers with BRAF mutations; however, patients ultimately develop therapeutic resistance through the activation of alternative signaling pathways such as RAF/RAS or MET. The authors hypothesized that combining the BRAF inhibitor vemurafenib with either the ...

journal_title：Cancer

authors： Janku F,Sakamuri D,Kato S,Huang HJ,Call SG,Naing A,Holley VR,Patel SP,Amaria RN,Falchook GS,Piha-Paul SA,Zinner RG,Tsimberidou AM,Hong DS,Meric-Bernstam F

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:The authors hypothesized that comprehensive genomic profiling of advanced-stage cutaneous squamous cell carcinoma (cSCC) could identify genomic-derived drug targets of therapy for patients with conventional therapy-resistant disease. METHODS:Comprehensive genomic profiling of 315 cancer genes was applied to...

journal_title：Cancer

authors： Al-Rohil RN,Tarasen AJ,Carlson JA,Wang K,Johnson A,Yelensky R,Lipson D,Elvin JA,Vergilio JA,Ali SM,Suh J,Miller VA,Stephens PJ,Ganesan P,Janku F,Karp DD,Subbiah V,Mihm MC,Ross JS

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:The AKT inhibitor MK-2206 at a dose of 60 mg every other day was evaluated in gastric/gastroesophageal junction cancers. METHODS:Patients who had progressed after first-line treatment were eligible. Pertinent eligibility criteria included adequate organ function, a fasting serum glucose level ≤ 150 mg/dL, a...

journal_title：Cancer

authors： Ramanathan RK,McDonough SL,Kennecke HF,Iqbal S,Baranda JC,Seery TE,Lim HJ,Hezel AF,Vaccaro GM,Blanke CD

更新日期：2015-07-01 00:00:00

abstract：:A primary fibrosarcoma of the thyroid occurring in a patient with a nodular goiter is described. Light microscopy showed interwoven bundles of spindle cells admixed with plump ovoid cells, and foci of multinucleated giant cells. Remnants of distorted thyroid follicles were found only at the periphery of the tumor. "Tr...

journal_title：Cancer

authors： Shin WY,Aftalion B,Hotchkiss E,Schenkman R,Berkman J

更新日期：1979-08-01 00:00:00

abstract：:Jaundice and hepatomegaly developed in a boy with Fanconi anemia after he had undergone treatment with oxymetholone for nine years. A liver scan showed patchy uptake consistent with the presence of space-occupying lesions. After oxymetholone treatment was stopped, the jaundice resolved, the liver size decreased, and t...

journal_title：Cancer

authors： Obeid DA,Hill FG,Harnden D,Mann JR,Wood BS

更新日期：1980-09-15 00:00:00

abstract：:A pilot study was done to determine the feasibility of adjuvant photodynamic therapy (PDT) in recurrent retroperitoneal sarcomas. Ten patients, who had recurrences after conventional methods of treatment, had repeated resections of the tumor and intraoperative photodynamic treatment to the tumor bed. The methods and e...

journal_title：Cancer

authors： Nambisan RN,Karakousis CP,Holyoke ED,Dougherty TJ

更新日期：1988-03-15 00:00:00

abstract：:A case of fatal acute hepatic vein thrombosis occurred during treatment for Hodgkin's disease. At necropsy no evidence of Hodgkin's disease or obliterative venoocclusive disease of the liver was found. We speculate that Adriamycin, DTIC and/or vinblastine may have been responsible for this unusual disorder. ...

journal_title：Cancer

authors： Houghton AN,Shafi N,Rickles FR

更新日期：1979-12-01 00:00:00

abstract：:Serum complements, C3, C4, and C3 proactivator (C3PA), were evaluated prospectively for their diagnostic power in detecting hepatocellular carcinoma (HCC) in patients with liver cirrhosis (LC). Sixty-three LC patients, including 36 LC with HCC patients, were recruited for this study during the period from March to Nov...

journal_title：Cancer

authors： Chang WY,Chuang WL

更新日期：1988-07-15 00:00:00

abstract：:A case of squamous cell carcinoma of the tongue in a 26-year-old man developing nine years after renal transplantation is presented. This is the first such case to be reported. Within seven months, widespread tumor metastases resulted in death. Pathologic examination of the transplanted kidney demonstrated neither re-...

journal_title：Cancer

authors： Lee YW,Gisser SD

更新日期：1978-01-01 00:00:00

abstract：BACKGROUND:We investigated p16(INK4A) expression in branchial cleft cysts and its utility in distinguishing branchial cleft cysts from metastatic head and neck squamous cell carcinomas (SCCs) in fine-needle aspiration biopsies (FNABs). METHODS:A study set comprising 41 resections (15 SCC and 26 branchial cleft cysts) ...

journal_title：Cancer

authors： Pai RK,Erickson J,Pourmand N,Kong CS

更新日期：2009-04-25 00:00:00

abstract：:The remaining tissue of the tracheobronchial tree from 210 men who died from lung cancer was studied to compare the histologic alterations leading to further sites of primary cancer. These men were uranium miners matched with nonminers for age and smoking habits. In the examination of a total of 28,928 cross-sections ...

journal_title：Cancer

authors： Auerbach O,Saccomanno G,Kuschner M,Brown RD,Garfinkel L

更新日期：1978-08-01 00:00:00

abstract：:This prospective evaluation of 5-fluorouracil (5-FU) and methyl-CCNU administered in combination to patients with surgery for histologically proved gastric adenocarcinoma is based upon 312 patients randomized between August 1974 and May 1980. Patients were stratified into three categories of resectability, (1) complet...

journal_title：Cancer

authors： Higgins GA,Amadeo JH,Smith DE,Humphrey EW,Keehn RJ

更新日期：1983-09-15 00:00:00

abstract：:It was shown previously that invasive human transitional cell carcinoma cell line EJ, but not the noninvasive RT4 cells, can degrade basement membrane laminin and that the degradation of basement membrane laminin was a result of a redistribution of activated cysteine proteinase cathepsin B to the plasma membrane of th...

journal_title：Cancer

authors： Redwood SM,Liu BC,Weiss RE,Hodge DE,Droller MJ

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND:The National Pediatric Oncology Unit (UNOP) is the only pediatric hemato-oncology center in Guatemala. METHODS:Patients ages 1 to 17 years with acute lymphoblastic leukemia (ALL) were treated according to modified ALL Intercontinental Berlin-Frankfurt-Münster (IC-BFM) 2002 protocol. Risk classification was ...

journal_title：Cancer

authors： Antillón FG,Blanco JG,Valverde PD,Castellanos M,Garrido CP,Girón V,Letona TR,Osorio EJ,Borrayo DA,Mack RA,Melgar MA,Lorenzana R,Ribeiro RC,Metzger M,Conter V,Rossi E,Valsecchi MG

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Fine-needle aspiration biopsy (FNAB) has been used with variable success as a diagnostic test for benign and malignant breast lesions. The goal of this study was to examine the effects of training physicians in the fine-needle aspiration sampling-technique on the diagnostic accuracy of FNAB of palpable breas...

journal_title：Cancer

authors： Ljung BM,Drejet A,Chiampi N,Jeffrey J,Goodson WH 3rd,Chew K,Moore DH 2nd,Miller TR

更新日期：2001-08-25 00:00:00

abstract：BACKGROUND:The objective of this study was to discover molecular biomarkers associated with the recurrence of esophageal squamous cell carcinoma (ESCC). METHODS:The authors retrospectively analyzed the hypermethylation status of 11 genes using methylation-specific polymerase chain reaction (PCR) and the expression of ...

journal_title：Cancer

authors： Lee E,Lee BB,Ko E,Kim Y,Han J,Shim YM,Park J,Kim DH

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Extrapulmonary inflammatory pseudotumor (plasma cell granuloma) is an uncommon lesion in adults and children, and little is known either of its etiology or clinical characteristics. However, it remains a significant source of morbidity to patients and confusion to clinicians. METHODS:Case reports are presen...

journal_title：Cancer

authors： Treissman SP,Gillis DA,Lee CL,Giacomantonio M,Resch L

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Despite the well-defined role of minimal residual disease (MRD) monitoring by real-time quantitative polymerase chain reaction (RT-PCR) for RUNX1/RUNX1T1 and CBFB-MYH11 transcripts in core binding factor (CBF) acute myeloid leukemia (AML) after intensive chemotherapy, there has been a paucity of data assessi...

journal_title：Cancer

authors： Yalniz FF,Patel KP,Bashir Q,Marin D,Ahmed S,Alousi AM,Chen J,Ciurea SO,Rezvani K,Popat UR,Shpall EJ,Champlin RE,Oran B

更新日期：2020-05-15 00:00:00

abstract：:A routine admission chest radiograph (CXR) in pediatric patients with cancer who are admitted to the hospital for fever and neutropenia has been advised because the signs and symptoms of pneumonia may be absent. The authors studied 131 consecutive patient admissions for fever and neutropenia to evaluate the diagnostic...

journal_title：Cancer

authors： Katz JA,Bash R,Rollins N,Cash J,Buchanan GR

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Whether patient navigation improves outcomes for patients with comorbidities is unknown. The aims of this study were to determine the effect of comorbidities on the time to diagnostic resolution after an abnormal cancer screening test and to examine whether patient navigation improves the timeliness and like...

journal_title：Cancer

authors： Whitley EM,Raich PC,Dudley DJ,Freund KM,Paskett ED,Patierno SR,Simon M,Warren-Mears V,Snyder FR,Patient Navigation Research Program Investigators.

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Treatment with traditional cytotoxic chemotherapy regimens containing streptozocin or dacarbazine has resulted in only marginal benefit for patients with metastatic neuroendocrine tumors. The use of these regimens has been further limited by their potential toxicity. Gemcitabine is generally well tolerated a...

journal_title：Cancer

authors： Kulke MH,Kim H,Clark JW,Enzinger PC,Lynch TJ,Morgan JA,Vincitore M,Michelini A,Fuchs CS

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Cervical carcinoma remains a significant health risk for the older woman. In the current study the yield of screening of mature women in an established, opportunistic screening program was examined. Strategies for improving screening in this age group were identified through examination of recent Pap test hi...

journal_title：Cancer

authors： Colgan TJ,Clarke A,Hakh N,Seidenfeld A

更新日期：2002-08-25 00:00:00

abstract：BACKGROUND:It remains controversial whether modified radical neck dissection (MRND) for patients with papillary thyroid carcinoma improves prognosis. However, it is highly probable that the incidence of local recurrence is reduced by lymph node dissection. Sentinel lymph node (SLN) biopsy (SLNB) for patients with melan...

journal_title：Cancer

authors： Fukui Y,Yamakawa T,Taniki T,Numoto S,Miki H,Monden Y

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:The presence of tumor at the inked margins (IMs) of breast specimens is associated with an increased risk of local recurrence after breast-conserving therapy for invasive breast carcinoma and ductal carcinoma in situ (DCIS). Given the importance of margin status, some have advocated the use of shaved margins...

journal_title：Cancer

authors： Guidi AJ,Connolly JL,Harris JR,Schnitt SJ

更新日期：1997-04-15 00:00:00

abstract：:An infant who presented with a thigh mass and coagulopathy was found to have a hemangioendothelioma. The tumor rapidly enlarged despite accepted therapeutic modalities, and the child died after a sudden cardiac arrest. Postmortem examination revealed a highly invasive tumor mass that had infiltrated the bowel and invo...

journal_title：Cancer

authors： Weinblatt ME,Kahn E,Kochen JA

更新日期：1984-11-15 00:00:00

abstract：BACKGROUND:Biomarker-guided clinical trials are increasingly common in metastatic urothelial carcinoma (mUC), yet patients for whom contemporary tumor tissue is not available are not eligible. Technological advancements in sequencing have made cell-free circulating DNA (cfDNA) next-generation sequencing (NGS) readily a...

journal_title：Cancer

authors： Agarwal N,Pal SK,Hahn AW,Nussenzveig RH,Pond GR,Gupta SV,Wang J,Bilen MA,Naik G,Ghatalia P,Hoimes CJ,Gopalakrishnan D,Barata PC,Drakaki A,Faltas BM,Kiedrowski LA,Lanman RB,Nagy RJ,Vogelzang NJ,Boucher KM,Vaishampa

更新日期：2018-05-15 00:00:00

abstract：:As the toll taken by breast cancer continues unabated, screening programs are widely perceived to play a critical role to improve diagnosis and successful treatment. Breast cancer screening programs are increasingly promoted to women; however, the economic implications of mass screening is a subject of much health pol...

journal_title：Cancer

authors： Mushlin AI,Fintor L

更新日期：1992-04-01 00:00:00

abstract：:Major advances have been made in melanoma treatment with the use of molecularly targeted therapies and immunotherapies, and numerous regimens are now approved by the US Food and Drug Administration for patients with stage IV disease. However, therapeutic resistance remains an issue to both classes of agents, and relia...

journal_title：Cancer

authors： Szczepaniak Sloane RA,Gopalakrishnan V,Reddy SM,Zhang X,Reuben A,Wargo JA

更新日期：2017-06-01 00:00:00