X;6 translocation in a child with congenital acute lymphocytic leukemia.

abstract：:Myelography was performed on 78 patients with breast cancer who had signs or symptoms compatible with spinal cord compression. Of 42 patients (54%) with extradural defects, 21 (50%) had a complete block. All patients with positive myelograms (M+) had a positive bone scan and 41 of 42 (97%) had positive skeletal x-rays...

journal_title：Cancer

authors： Harrison KM,Muss HB,Ball MR,McWhorter M,Case D

更新日期：1985-06-15 00:00:00

abstract：BACKGROUND:Glioblastoma, which is the most malignant brain tumor, remains incurable and almost always causes death. As a new treatment strategy, the combination of all-trans retinoic acid (ATRA) and paclitaxel was explored for controlling the growth of glioblastoma U87MG xenografts. METHODS:Human glioblastoma U87MG xe...

journal_title：Cancer

authors： Karmakar S,Banik NL,Ray SK

更新日期：2008-02-01 00:00:00

abstract：:A study of the effects of local tumor radiation alone (1500R) and cyclophosphamide alone (150 mg/kg) on the experimental solid tumor rat hepatoma 3924A has been completed. Cyclophosphamide was more effective in controlling tumor growth than either radiation or 5-fluorouracil (5-FU) (150 mg/kg) previously reported. Par...

journal_title：Cancer

authors： Looney WB,Hopkins HA,Grover WH,Macleod MS,Ritenour ER,Hobson AS

更新日期：1980-06-01 00:00:00

abstract：BACKGROUND:Fortunately, primary malignant mucosal melanoma of the head and neck is a rare entity. A paucity of data elucidating the predictive factors as well as the unpredictable and aggressive biologic behavior of mucosal melanoma compound the vexing clinical situation. This review summarizes what the literature reve...

journal_title：Cancer

authors： Manolidis S,Donald PJ

更新日期：1997-10-15 00:00:00

abstract：BACKGROUND:Immediate or early postmastectomy breast reconstruction is performed infrequently. To the authors' knowledge, little is known regarding surgeon or patient perspectives on reconstruction treatment decisions. The purpose of the current study was to identify patient attitudes and preferences associated with bre...

journal_title：Cancer

authors： Morrow M,Mujahid M,Lantz PM,Janz NK,Fagerlin A,Schwartz K,Liu L,Deapen D,Salem B,Lakhani I,Katz SJ

更新日期：2005-12-01 00:00:00

abstract：:For 52 patients with depressed adenomas of the stomach, histopathologic studies were done on 56 tumors and for 43 of them, histochemical and immunohistochemical features were examined. In addition, nondepressed adenomas (n = 57) and the depressed type of early gastric adenocarcinomas of the well-differentiated variety...

journal_title：Cancer

authors： Xuan ZX,Ambe K,Enjoji M

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Despite recent advances in diagnosis and treatment, gastric carcinoma remains a major cause of death in the world. METHODS:The clinicopathologic profile of 10,000 consecutive patients who underwent primary gastrectomy during 1962-1989 were reviewed and prognostic factors influencing survival in those with g...

journal_title：Cancer

authors： Nakamura K,Ueyama T,Yao T,Xuan ZX,Ambe K,Adachi Y,Yakeishi Y,Matsukuma A,Enjoji M

更新日期：1992-09-01 00:00:00

abstract：:To determine the efficacy of adjuvant chemotherapy in patients with advanced head and neck squamous carcinoma, the National Cancer Institute initiated a multi-institutional, prospective randomized trial termed the Head and Neck Contracts Program. Between 1978 and 1982, 462 patients with resectable Stage III or IV canc...

journal_title：Cancer

authors：

更新日期：1987-08-01 00:00:00

abstract：:We counted the number of toluidine blue positive mast cells within and around the tumor in 44 patients with soft tissue sarcomas (STS). Irrespective of their histologic types, these cases were broadly divided into the following two groups: (1) low count (less than 20 mast cells/10 high-power fields [HPF]) and (2) high...

journal_title：Cancer

authors： Ueda T,Aozasa K,Tsujimoto M,Yoshikawa H,Kato T,Ono K,Matsumoto K

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND:Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults. Temozolomide was rapidly incorporated into first-line treatment following the publication of the pivotal European Organization for Research and Treatment of Cancer-National Cancer Institute of Canada phase 3 trial in 2005. Howe...

journal_title：Cancer

authors： Lawrence YR,Mishra MV,Werner-Wasik M,Andrews DW,Showalter TN,Glass J,Shen X,Symon Z,Dicker AP

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related peptide (PTHrP) is a tumor-derived circulating factor that has been associated with hypercalcemia of malignancy. The role of PTHrP as a prognostic indicator remains unclear. Studies suggest that it may function as a growth factor; and, recently, the ability of PTHrP to induce cyto...

journal_title：Cancer

authors： Deans C,Wigmore S,Paterson-Brown S,Black J,Ross J,Fearon KC

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Although thin cutaneous melanomas generally have a favorable prognosis, in some cases they may undergo progression. The current study was undertaken to identify variables that may predict a more aggressive clinical outcome in these patients. In addition to classic clinicopathologic features, the authors test...

journal_title：Cancer

authors： Massi D,Franchi A,Borgognoni L,Reali UM,Santucci M

更新日期：1999-03-01 00:00:00

abstract：:Autopsy slides from 22 melanoma patients who received bacille Calmette-Guérin BCG immunotherapy and who had a postmortem examination at the UCLA Center for the Health Sciences were examined for the presence of granulomas. Granulomas were found in six patients (29%) who received BCG but not in a group of 25 melanoma pa...

journal_title：Cancer

authors： Hatzitheofilou C,Obenchain DF,Porter DD,Morton DL

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:Cytology and core-needle biopsies are not always sufficient to exclude malignancy in benign breast lesions (BBL) that are at risk of developing cancer, and open biopsy often is mandatory. In screening programs, open biopsies performed for lesions that are at risk of developing malignancy are considered benig...

journal_title：Cancer

authors： Manfrin E,Mariotto R,Remo A,Reghellin D,Falsirollo F,Dalfior D,Bricolo P,Piazzola E,Bonetti F

更新日期：2009-02-01 00:00:00

abstract：:Disparities in minorities' representation in cancer clinical trials have been shown only in adult populations, which suggest that the main causes of these disparities relate to health system-based barriers, including issues of poverty (lack of insurance), poor access to trials, and an inadequate number of clinical tri...

journal_title：Cancer

authors： Colon-Otero G,Smallridge RC,Solberg LA Jr,Keith TD,Woodward TA,Willis FB,Dunn AN

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Some studies have suggested that the use of calcium channel blockers may increase the risk of cancer. A possible association of the use of calcium channel blockers with cancer incidence and cancer mortality was addressed using data from the Nurses' Health Study. METHODS:In this study, a total of 18,635 fema...

journal_title：Cancer

authors： Michels KB,Rosner BA,Walker AM,Stampfer MJ,Manson JE,Colditz GA,Hennekens CH,Willett WC

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Patients who present with squamous cell carcinoma metastatic to cervical lymph nodes and no clinically apparent primary site present a therapeutic dilemma. Positron emission tomography imaging with 2-[F-18]fluoro-2-deoxy-D-glucose (FDG-PET) has been shown to be useful for the examination of known primary tum...

journal_title：Cancer

authors： Greven KM,Keyes JW Jr,Williams DW 3rd,McGuirt WF,Joyce WT 3rd

更新日期：1999-07-01 00:00:00

abstract：:Patients with advanced head and neck cancer have significant reduction in their circulating lymphocyte mass which is reflected in decreased numbers of T cells, Fc receptor cells, and in derangements of T lymphocyte functions, i.e., decreased responsiveness to several dilutions of phytohemagglutinin and lack of develop...

journal_title：Cancer

authors： Zighelboim J,Dorey F,Parker NH,Calcaterra T,Ward P,Fahey JL

更新日期：1979-07-01 00:00:00

abstract：:Research trends on quality of life outcomes for cancer survivors are discussed. Epidemiologic data indicate that female cancer survivors, coming primarily from patient groups with gynecologic, breast, and colorectal cancers, will outnumber male survivors 3 to 1. Male survivors will come from the ranks of patient group...

journal_title：Cancer

authors： Andersen BL

更新日期：1994-08-15 00:00:00

abstract：:This report describes a case of null cell congenital acute lymphoblastic leukemia associated with a (4;11) translocation. This chromosome abnormality is associated with acute lymphoblastic leukemia and probably more specifically with congenital acute lymphoblastic leukemia. A review of the literature is presented. ...

journal_title：Cancer

authors： Esseltine DW,Vekemans M,Seemayer T,Reece E,Gordon J,Whitehead VM

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:Gemcitabine-associated thrombotic microangiopathy (TMA) is believed to be very rare, with an estimated incidence rate of 0.015%. Indications for gemcitabine are expanding, and comprehensive characterization of this complication is therefore important. METHODS:The authors performed a retrospective chart revi...

journal_title：Cancer

authors： Humphreys BD,Sharman JP,Henderson JM,Clark JW,Marks PW,Rennke HG,Zhu AX,Magee CC

更新日期：2004-06-15 00:00:00

abstract：:Retinoblastoma should not be considered as the exceptional childhood cancer that shows dominant inheritance, but rather as the typical childhood cancer that embraces a prezygotic and postzygotic subgroup. Postzygotic cases are conceived as involving mutation as a first step too, but with the mutation in somatic rather...

journal_title：Cancer

authors： Knudson AG Jr

更新日期：1975-03-01 00:00:00

abstract：BACKGROUND:For the current report, the authors examined the characteristic features of morphology and molecular biology of phosphatase and tensin homolog (PTEN), beta-catenin, and p53 immunocytochemistry in endometrial carcinoma by using thin-layer cytologic preparations. METHODS:During a 6-month period, 120 endometri...

journal_title：Cancer

authors： Norimatsu Y,Miyamoto M,Kobayashi TK,Moriya T,Shimizu K,Yanoh K,Tsukayama C,Miyake Y,Ohno E

更新日期：2008-06-25 00:00:00

abstract：BACKGROUND:Patients with metastatic melanoma (MM) have very few therapy options. Based on reports of responses to paclitaxel and carboplatin (PC), 31 patients with MM were treated with PC. METHODS:Data regarding patients treated with PC were abstracted from medical records. Clinical outcomes as determined by the treat...

journal_title：Cancer

authors： Rao RD,Holtan SG,Ingle JN,Croghan GA,Kottschade LA,Creagan ET,Kaur JS,Pitot HC,Markovic SN

更新日期：2006-01-15 00:00:00

abstract：:The clinical findings in 262 patients with melanoma were correlated with an assessment of their cellular-mediated immunity by delayed-type hypersensitivity (DTH) skin tests, by lymphocyte blastogenesis, and by leukocyte enumerations. Patients with systemic metastases (stage IV) and those with evidence of tumor burden ...

journal_title：Cancer

authors： Pritchard DJ,Ritts RE Jr,Taylor WF,Miller GC

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:The primary objective of this study was to clarify the significance of p21WAF1/CIP1(p21) gene expression in the tumorgenicity of hepatitis B virus (HBV) and hepatitis C virus (HCV) infected human hepatocelluar carcinoma (HCC). METHODS:The authors performed Northern blot hybridization to compare the p21 mess...

journal_title：Cancer

authors： Kobayashi S,Matsushita K,Saigo K,Urashima T,Asano T,Hayashi H,Ochiai T

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The axon guidance cue molecule Slit2 has been shown to suppress cancer cell invasion. However, the role of Slit2 in growth inhibition is still controversial. The authors identified a novel exon 15 (AKEQYFIP)-deleted slit2, located at the end of the second leucine-rich repeat (LRR2). Because LRR2 interacts wi...

journal_title：Cancer

authors： Lin YY,Yang CH,Sheu GT,Huang CY,Wu YC,Chuang SM,Fann MJ,Chang H,Lee H,Chang JT

更新日期：2011-08-01 00:00:00

abstract：BACKGROUND:An Investigational New Drug (IND) treatment program allows patients access to a drug that has shown activity against a serious or life-threatening disease prior to full Food and Drug Administration (FDA) review and approval. This treatment IND program, in which patients with locally advanced or metastatic pa...

journal_title：Cancer

authors： Storniolo AM,Enas NH,Brown CA,Voi M,Rothenberg ML,Schilsky R

更新日期：1999-03-15 00:00:00

abstract：:Adrenal cortical carcinoma is an uncommon neoplasm in children. Only a handful of congenital adrenal cortical carcinoma cases have been described. A newborn who had metastatic adrenal cortical carcinoma (skin metastases and cerebral lesions) is described. This patient underwent surgical resection of the right adrenal ...

journal_title：Cancer

authors： Saracco S,Abramowsky C,Taylor S,Silverman RA,Berman BW

更新日期：1988-08-01 00:00:00

abstract：BACKGROUND:Radiation recall refers to a tissue reaction produced by a chemotherapeutic agent in a previously irradiated field that would not occur in a nonirradiated field. A number of agents have been reported to cause radiation recall. Recently, there have been case reports of recall dermatitis from paclitaxel treatm...

journal_title：Cancer

authors： Schweitzer VG,Juillard GJ,Bajada CL,Parker RG

更新日期：1995-09-15 00:00:00