The effects of pain severity on health-related quality of life: a study of Chinese cancer patients.

Abstract:

BACKGROUND:The health-related functioning of patients with cancer is compromised by several factors, including the disease process, treatment, and the various symptoms that are produced by both disease and treatment. This study was designed to specify the relationship between patients' pain severity and their self-reported quality of life. METHODS:The study enrolled 216 consecutive consenting adult patients from 2 Chinese cancer centers with pathologically-diagnosed metastatic cancer who could understand and complete the self-report measures. The majority had cancer-related pain and were receiving analgesics. The Chinese version of the Brief Pain Inventory was used to assess the severity and interference of pain. A Chinese translation of the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36) was used to assess health-related functional status. Patients' physicians completed a form that indicated characteristics of the patients' cancer, Eastern Cooperative Oncology Group performance status, pain, and current pain treatment. RESULTS:Increasing severity of pain was associated with worsening health-related functioning, even when an estimate of disease severity was taken into account. The correlation between pain severity and impairment was nonlinear. The functional health and well-being of cancer patients with no or mild pain was significantly less impaired than that of patients with moderate or severe pain. The impairment of patients with moderate and severe pain did not differ. CONCLUSIONS:Pain severity is an important variable to be taken into account when quality of life outcome measures are considered. The functioning of cancer patients with well-controlled (mild) pain did not differ significantly from that of patients without pain. Providing pain relief should significantly improve the functional status of cancer patients.

journal_name

Cancer

journal_title

Cancer

authors

Wang XS,Cleeland CS,Mendoza TR,Engstrom MC,Liu S,Xu G,Hao X,Wang Y,Ren XS

subject

Has Abstract

pub_date

1999-11-01 00:00:00

pages

1848-55

issue

9

eissn

0008-543X

issn

1097-0142

pii

10.1002/(SICI)1097-0142(19991101)86:9<1848::AID-CN

journal_volume

86

pub_type

杂志文章

相关文献

CANCER文献大全
  • Combined modality therapy in Stage III and Stage IIIE diffuse large cell lymphomas.

    abstract::Combined modality therapy consisting of CHOP-Bleo (cyclophosphamide, Adriamycin [doxorubicin], vincristine (Oncovin), prednisone, and bleomycin) and limited-field radiotherapy was given to 47 patients with Stage III and IIIE diffuse large cell lymphomas. Overall 5-year survival and disease-free survival figures are 64...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840401)53:7<1478::aid-cncr2820

    authors: Velasquez W,Fuller LM,Oh KK,Hagemeister FB,Sullivan JA,Manning JT,Shullenberger CC

    更新日期:1984-04-01 00:00:00

  • The role of tumor resection in the treatment of glioblastoma multiforme in adults.

    abstract:BACKGROUND:The therapeutic impact of tumor resection is poorly defined. Therefore the current study was conducted. METHODS:A retrospective, 2-institutional study was conducted (1991-1994) to compare the treatment results of stereotactic biopsy plus radiation therapy (99 patients; tumor dose: 60 gray [Gy]) with those o...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:

    authors: Kreth FW,Berlis A,Spiropoulou V,Faist M,Scheremet R,Rossner R,Volk B,Ostertag CB

    更新日期:1999-11-15 00:00:00

  • A nonrandom association between gastrointestinal stromal tumors and myeloid leukemia.

    abstract:BACKGROUND:Gastrointestinal stromal tumors (GISTs) are KIT-positive mesenchymal tumors of the gastrointestinal tract that are driven by activated KIT-signalling or platelet-derived growth factor receptor-alpha (PDFGRA) signaling. These tumors most commonly occur in the stomach and small intestine and encompass a clinic...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23216

    authors: Miettinen M,Kraszewska E,Sobin LH,Lasota J

    更新日期:2008-02-01 00:00:00

  • Alpha-fetoprotein and human chorionic gonadotropin in a patient with a primary intracranial germ cell tumor.

    abstract::A 17 year old man with a primary intracranial germ cell tumor in the pituitary region is reported. Both serum alpha-fetoprotein (AFP) and serum human chorionic gonadotropin (hCG) were found elevated preoperatively. Normal levels of serum AFP and hCG were found after operation and radiotherapy. By indirect immunofluore...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197806)41:6<2315::aid-cncr282041

    authors: Nørgaard-Pedersen B,Lindholm J,Albrechtsen R,Arends J,Diemer NH,Riishede J

    更新日期:1978-06-01 00:00:00

  • Genetic testing and counseling for hereditary forms of colorectal cancer.

    abstract::The discovery of genes responsible for inherited forms of colorectal cancer have the potential to improve cancer risk assessment and counseling. Germline mutations (nonsense, frameshift) of APC are associated with familial adenomatous polyposis, an autosomal dominant syndrome, clinically characterized by young onset, ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1097-0142(19991201)86:11+<2540::aid-

    authors: Petersen GM,Brensinger JD,Johnson KA,Giardiello FM

    更新日期:1999-12-01 00:00:00

  • Therapy of meningeal melanocytomas.

    abstract:BACKGROUND:Meningeal melanocytomas are rare, benign central nervous system lesions with a high probability of recurrence. To the authors' knowledge, approximately 100 cases have been reported since 1972, when the entity first was described. In the current study, four therapies were compared with regard to local control...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20296

    authors: Rades D,Schild SE,Tatagiba M,Molina HA,Alberti W

    更新日期:2004-06-01 00:00:00

  • Phase I clinical trial and pharmacokinetics of carboplatin (NSC 241240) by single monthly 30-minute infusion.

    abstract::Carboplatin (diammine [1,1-cyclobutanedicarboxylate(2-)-O,o']platinum) is a second generation platinum coordination complex. It has a spectrum of activity that is similar to that of cisplatin and is less nephrotoxic and emetogenic in experimental animals. Fifty-two 30-minute infusions of carboplatin were given to 20 e...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860115)57:2<222::aid-cncr28205

    authors: Koeller JM,Trump DL,Tutsch KD,Earhart RH,Davis TE,Tormey DC

    更新日期:1986-01-15 00:00:00

  • Comparison of primary osteosarcoma of flat bones with secondary osteosarcoma of any site.

    abstract:BACKGROUND:The authors hypothesized that the outcomes for young patients who present with primary osteosarcoma of flat bones or secondary osteosarcoma after other primary malignancies are similar because the sites of these tumors rarely makes them amenable to complete surgical resection. METHODS:The authors reviewed t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Pratt CB,Meyer WH,Rao BN,Pappo AS,Fleming ID,Luo X,Cain A,Kaste SC,Shearer PD,Jenkins JJ 3rd

    更新日期:1997-09-15 00:00:00

  • Efficacy of ondansetron against nausea and vomiting caused by dacarbazine-containing chemotherapy.

    abstract:BACKGROUND AND METHODS:The antiemetic activity of ondansetron (Zofran, Glaxo Pharmaceuticals, Research Triangle Park, NC) was evaluated in 25 patients with recurrent melanoma who were treated sequentially with dacarbazine (DTIC), vinblastine, and cisplatin. The antiemetic regimen included ondansetron alone in 11 patien...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19921001)70:7<2018::aid-cncr2820

    authors: Legha SS,Hodges C,Ring S

    更新日期:1992-10-01 00:00:00

  • Histologic features and clinical significance of venous invasion in colorectal carcinoma with hepatic metastasis.

    abstract:BACKGROUND:In colorectal carcinoma, venous invasion has been related to patient survival. Liver metastasis develops more frequently when venous invasion is present. However, the histologic features and clinical significance of venous invasion are not well understood. METHODS:A histologic study of venous invasion in co...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19961201)78:11<2313::aid-c

    authors: Ouchi K,Sugawara T,Ono H,Fujiya T,Kamiyama Y,Kakugawa Y,Mikuni J,Tateno H

    更新日期:1996-12-01 00:00:00

  • Developing epidemic of melanoma in the Hispanic population of California.

    abstract:BACKGROUND:Hispanics comprise almost one-third of the population of California, are the most rapidly increasing racial/ethnic group in the state, and represent almost one-third of all Hispanics in the U.S. California has among the highest rates of melanoma in the world, yet little is known about trends in melanoma in i...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21654

    authors: Cockburn MG,Zadnick J,Deapen D

    更新日期:2006-03-01 00:00:00

  • A comparison of screening mammography results from programs for women of different socioeconomic status.

    abstract:BACKGROUND:The ability of screening mammography programs serving women of different socioeconomic status (SES) to diagnose early stage breast carcinoma in a comparably effective fashion has been questioned. METHODS:Results of screening 50,653 women of lower SES were compared with those of screening 45,923 more socioec...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19980501)82:9<1692::aid-cn

    authors: Dershaw DD,Loring L,True SJ,Momrow DC,Liberman L,Morris EA

    更新日期:1998-05-01 00:00:00

  • Use of adjuvant radiotherapy at hospitals with and without on-site radiation services.

    abstract:BACKGROUND:In many areas of health care, whether patients receive specific medical interventions often is influenced heavily by the local availability of resources for delivering those services. However, relations between resource availability and utilization are relatively unexplored in cancer care, including perioper...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22458

    authors: Wong SL,Wei Y,Birkmeyer JD

    更新日期:2007-02-15 00:00:00

  • Prolonged remissions in adults with acute leukemia following late intensification chemotherapy and immunotherapy.

    abstract::Sixty-two patients with acute leukemia who remained in continuous complete remission for 8 to 45 months received three courses of intensified therapy with new chemotherapeutic agents, after which they received no further chemotherapy. Immunotherapy with BCG was then administered to 55 of these patients. They have been...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19810415)47:8<1937::aid-cncr2820

    authors: Bodey GP,Freireich EJ,McCredie KB,Smith TL,Gehan EA,Gutterman JU,Hersh EM

    更新日期:1981-04-15 00:00:00

  • Patterns of care for women with cervical cancer in the United States.

    abstract:BACKGROUND:Recommendations for pretreatment evaluation and treatment of cervical cancer have significantly evolved over the last decade because of the results of multiple randomized studies comparing the addition of platin-based chemoradiation as well as the widespread dissemination and use of imaging modalities. This ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23682

    authors: Trimble EL,Harlan LC,Gius D,Stevens J,Schwartz SM

    更新日期:2008-08-15 00:00:00

  • Diagnostic accuracy of fine-needle aspiration biopsy is determined by physician training in sampling technique.

    abstract:BACKGROUND:Fine-needle aspiration biopsy (FNAB) has been used with variable success as a diagnostic test for benign and malignant breast lesions. The goal of this study was to examine the effects of training physicians in the fine-needle aspiration sampling-technique on the diagnostic accuracy of FNAB of palpable breas...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.9040

    authors: Ljung BM,Drejet A,Chiampi N,Jeffrey J,Goodson WH 3rd,Chew K,Moore DH 2nd,Miller TR

    更新日期:2001-08-25 00:00:00

  • Nutrients, vitamins and minerals as therapy.

    abstract::Nutrients as therapy for patients with cancer are important as adjunctive therapy, i.e., adequate nutrition may be important for the success of whatever form of therapy is administered. Diets deficient in certain amino acids have some selectivity when tested against experimental tumors propagated in vivo. Such diets h...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197905)43:5+<2137::aid-cncr28204

    authors: Bertino JR

    更新日期:1979-05-01 00:00:00

  • Lymphoplasmacytic lymphoma. Report of a case with three monoclonal proteins derived from a single neoplastic clone.

    abstract::The unique case of a 60-year-old patient with a non-Hodgkin's B-cell lymphoma of the lymphoplasmacytic type and three associated monoclonal proteins, is described. The patient also exhibited various autoimmune phenomena that were consistent with the diagnoses of Sjögren's syndrome and autoimmune thyroiditis. The evolu...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860501)57:9<1794::aid-cncr2820

    authors: Berg AR,Weisenburger DD,Linder J,Armitage JO

    更新日期:1986-05-01 00:00:00

  • Detection of recurrent or persistent nasopharyngeal carcinomas after radiotherapy with technetium-99m methoxyisobutylisonitrile single photon emission computed tomography and computed tomography: comparison with 18-fluoro-2-deoxyglucose positron emission

    abstract:BACKGROUND:The diagnostic accuracy of technetium-99m methoxyisobutylisonitrile (Tc-MIBI) single photon emission computed tomography (SPECT) and computed tomography (CT) of the head and neck for differentiating recurrent or residual nasopharyngeal carcinomas (NPC) from benign lesions after radiotherapy was compared with...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/cncr.10400

    authors: Kao CH,Shiau YC,Shen YY,Yen RF

    更新日期:2002-04-01 00:00:00

  • Decision-support networks of women newly diagnosed with breast cancer.

    abstract:BACKGROUND:Little is known about the size and characteristics of the decision-support networks of women newly diagnosed with breast cancer and whether their involvement improves breast cancer treatment decisions. METHODS:A population-based sample of patients newly diagnosed with breast cancer in 2014 and 2015, as repo...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.30848

    authors: Wallner LP,Li Y,McLeod MC,Hamilton AS,Ward KC,Veenstra CM,An LC,Janz NK,Katz SJ,Hawley ST

    更新日期:2017-10-15 00:00:00

  • Ferritin-bearing lymphocytes in the diagnosis of breast cancer.

    abstract::Four hundred forty-seven women attending a breast clinic because of either suspicious lesions, anxiety about breast cancer, follow-up after the removal of a benign breast lesion, or a family history of breast cancer had a routine test for percentage of ferritin-bearing lymphocytes ( FBL ) in their peripheral blood. Am...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19840701)54:1<84::aid-cncr282054

    authors: Moroz C,Kan M,Chaimof C,Marcus H,Kupfer B,Cuckle HS

    更新日期:1984-07-01 00:00:00

  • Intensity-modulated radiotherapy reduces toxicity with similar biochemical control compared with 3-dimensional conformal radiotherapy for prostate cancer: A randomized clinical trial.

    abstract:BACKGROUND:The objective of this article was to report the results from a randomized clinical trial comparing intensity-modulated radiotherapy (IMRT) with 3-dimensonal conformal radiotherapy (3DCRT) for the treatment of prostate cancer on a hypofractionated schedule. METHODS:The authors randomly assigned 215 men who h...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.29983

    authors: Viani GA,Viana BS,Martin JE,Rossi BT,Zuliani G,Stefano EJ

    更新日期:2016-07-01 00:00:00

  • A comparison between combination chemotherapy and total body irradiation plus combination chemotherapy in non-Hodgkin's lymphoma.

    abstract::Thirty-nine untreated patients with either lymphocytic or nodular mixed/nodular histiocytic non-Hodgkin's lymphoma, stage II--IV, were randomized to treatment with total body irradiation (TBI), 100 rads in 10 fractions over 12 days, plus combination chemotherapy with either cyclophosphamide, vincristine and prednisone...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(197906)43:6<2227::aid-cncr282043

    authors: Brereton HD,Young RC,Longo DL,Kirkland LR,Berard CW,Jaffe ES,DeVita VT,Johnson RE

    更新日期:1979-06-01 00:00:00

  • Investigation of taxol as a potential radiation sensitizer.

    abstract:BACKGROUND:The authors evaluated the effects of taxol, a microtubular inhibitor, as a possible radiation sensitizer on the human leukemic cell line (HL-60). Taxol acts as a mitotic inhibitor, blocking cells in the G2M-phase of the cell cycle. The differential radiation sensitivity of cells in various phases of the cell...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930601)71:11<3774::aid-cncr282

    authors: Choy H,Rodriguez FF,Koester S,Hilsenbeck S,Von Hoff DD

    更新日期:1993-06-01 00:00:00

  • Preoperative chemotherapy treatment of breast cancer--a review.

    abstract::Despite proven benefits of neoadjuvant chemotherapy in patients with locally advanced, invasive breast cancer, no regimen is recommended as the treatment of choice. Neoadjuvant chemotherapy regimens encompass single-agent and combination therapy and sequential treatment. For this report, the author reviewed the litera...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.23083

    authors: Buzdar AU

    更新日期:2007-12-01 00:00:00

  • Racial and Ethnic Disparities in Travel for Head and Neck Cancer Treatment and the Impact of Travel Distance on Survival.

    abstract:BACKGROUND:Patients who travel a long distance (≥50 miles) for cancer care have improved outcomes. However, to the authors' knowledge, the prevalence of long travel distances for treatment by patients with head and neck squamous cell carcinoma (HNSCC), and the effect of travel distance on overall survival (OS), remains...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31571

    authors: Graboyes EM,Ellis MA,Li H,Kaczmar JM,Sharma AK,Lentsch EJ,Day TA,Hughes Halbert C

    更新日期:2018-08-01 00:00:00

  • Oat-cell carcinoma of the thymus.

    abstract::Oat-cell carcinoma of the thymus gland is exceedingly rare as a primary lesion, and only a few cases have been reported. We report a case in which a neoplasm interpreted as an oat-cell carcinoma was intimately associated with and arose in transition from a carcinoid tumor of the thymus. Ultrastructural features of thi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820415)49:8<1652::aid-cncr2820

    authors: Wick MR,Scheithauer BW

    更新日期:1982-04-15 00:00:00

  • Serum acute phase reactants and prognosis in renal cell carcinoma.

    abstract:BACKGROUND:Inflammatory parameters as acute phase proteins commonly are elevated in patients with renal cell carcinoma. Some of these acute phase reactants have been proposed to influence survival. METHODS:In 170 patients with renal cell carcinoma, the authors studied six acute phase reactant parameters (erythrocyte s...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19951015)76:8<1435::aid-cncr2820

    authors: Ljungberg B,Grankvist K,Rasmuson T

    更新日期:1995-10-15 00:00:00

  • Viral oncolysate in the management of malignant melanoma. II. Clinical studies.

    abstract::Melanoma cell oncolysate, prepared with Newcastle disease virus, was administered as an immunostimulant to 13 patients with metastatic melanoma. The oncolysate was well tolerated. Six treated patients evidenced a decrease in the size of skin nodules or diseased lymph nodes. Visceral lesions were not favorably influenc...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197708)40:2<680::aid-cncr2820400

    authors: Murray DR,Cassel WA,Torbin AH,Olkowski ZL,Moore ME

    更新日期:1977-08-01 00:00:00

  • Clinical and economic burden associated with stage III to IV triple-negative breast cancer: A SEER-Medicare historical cohort study in elderly women in the United States.

    abstract:BACKGROUND:The current study was performed to describe patient characteristics, treatment patterns, survival, health care resource use (HRU), and costs among older women in the United States with advanced (American Joint Committee on Cancer stage III/IV) triple-negative breast cancer (TNBC) in the Surveillance, Epidemi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31299

    authors: Schwartz KL,Simon MS,Bylsma LC,Ruterbusch JJ,Beebe-Dimmer JL,Schultz NM,Flanders SC,Barlev A,Fryzek JP,Quek RGW

    更新日期:2018-05-15 00:00:00