Breast-conserving surgery and radiation after augmentation mammoplasty.

Abstract:

BACKGROUND:Although breast-conserving therapy (tumor excision, axillary node dissection, and postoperative radiation) for women with breast cancer yields survival and local recurrence rates comparable with those of modified radical mastectomy, studies suggest that postoperative radiation leads to capsular contractures and poor cosmesis in patients with breast implants. METHODS:The authors followed 20 women in whom breast cancer developed after augmentation mammoplasty (14 subcutaneous implants and 6 retromuscular implants). Average age at diagnosis was 52 years (range, 34-72 years). Most (55%) of the patients had tumors in the upper outer quadrant. Fifteen lesions were palpable and five were nonpalpable. All tumors were excised using wide margins that attempted to include a rim of normal breast tissue. Three patients had microscopically positive margins. The predominant histology was ductal adenocarcinoma (85%). The mean greatest tumor dimension was 1.43 cm; 75% were T1 lesions. Levels I and II axillary lymph node dissection revealed metastases in five patients. After surgery, six patients received systemic chemotherapy, and all patients received 4500-5000 cGy of tangential photon radiation delivered to the whole breast, plus a 1400-2100 cGy boost delivered to the tumor site using photon radiation, electron radiation, or iridium 192 implantation. RESULTS:At a median follow-up of 3.8 years (range, 6 months to 9.3 years), there were no local recurrences; however, in two patients distant metastases developed. Seventeen (85%) of the twenty patients had good or excellent cosmetic results as determined by the degree of capsular contracture, breast shape and appearance, and the presence of skin changes. CONCLUSIONS:The authors conclude that breast-conserving therapy is a cosmetically acceptable therapeutic option for women in whom breast cancer develops after augmentation mammoplasty.

journal_name

Cancer

journal_title

Cancer

authors

Guenther JM,Tokita KM,Giuliano AE

doi

10.1002/1097-0142(19940515)73:10<2613::aid-cncr282

subject

Has Abstract

pub_date

1994-05-15 00:00:00

pages

2613-8

issue

10

eissn

0008-543X

issn

1097-0142

journal_volume

73

pub_type

杂志文章

相关文献

CANCER文献大全
  • Chemotherapy for metastatic Merkel cell carcinoma. Review of the M.D. Anderson Hospital's experience.

    abstract::Thirteen patients with regional or distant metastases from Merkel cell carcinoma were treated with combination chemotherapy. Three patients had a complete response to therapy. In two patients with nodal disease the duration of response was 10+ and 4+ years. In addition, three patients had a partial response, and six p...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19880815)62:4<683::aid-cncr28206

    authors: Feun LG,Savaraj N,Legha SS,Silva EG,Benjamin RS,Burgess MA

    更新日期:1988-08-15 00:00:00

  • Suppression of proline-directed protein kinase F(A) expression potentiates erythroid differentiation of human myeloid leukemia cells.

    abstract:BACKGROUND:Initial clinic studies revealed that the overexpression of proline-directed protein kinase F(A) (PDPK F(A)) is associated conversely with various stages of tumor tissue differentiation. However, the role of overexpressed PDPK F(A) in tumor cell differentiation remains unknown and needs to be established. In ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Hsu CP,Yang CC,Yang SD

    更新日期:2000-09-01 00:00:00

  • Percutaneous tumor ablation with radiofrequency.

    abstract:BACKGROUND:Radiofrequency thermal ablation (RFA) is a new minimally invasive treatment for localized cancer. Minimally invasive surgical options require less resources, time, recovery, and cost, and often offer reduced morbidity and mortality, compared with more invasive methods. To be useful, image-guided, minimally i...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.10234

    authors: Wood BJ,Ramkaransingh JR,Fojo T,Walther MM,Libutti SK

    更新日期:2002-01-15 00:00:00

  • Promoting colonoscopy screening among low-income Latinos at average risk of colorectal cancer: A randomized clinical trial.

    abstract:BACKGROUND:Screening colonoscopy (SC) for colorectal cancer (CRC) is underused by Latino individuals. The current randomized clinical trial examined the impact of 3 interventions: 1) patient navigation; 2) patient navigation plus standard Centers for Disease Control and Prevention print materials; and 3) patient naviga...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.32541

    authors: DuHamel KN,Schofield EA,Villagra C,Sriphanlop P,Itzkowitz SH,Cotter G,Cohen N,Erwin DO,Winkel G,Thompson HS,Zauber AG,Jandorf LH

    更新日期:2020-02-15 00:00:00

  • Automated analysis of mammographic densities and breast carcinoma risk.

    abstract:BACKGROUND:There is considerable evidence that one of the strongest risk factors for breast carcinoma can be assessed from the mammographic appearance of the breast. However, the magnitude of the risk factor and the reliability of the prediction depend on the method of classification. Subjective classification requires...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19970701)80:1<66::aid-cncr

    authors: Byng JW,Yaffe MJ,Lockwood GA,Little LE,Tritchler DL,Boyd NF

    更新日期:1997-07-01 00:00:00

  • The elderly population. Opportunities for cancer prevention and detection.

    abstract::Interest in the elderly population, persons 65 years of age or older, as a target group for cancer control has not been great. Age recommendations rarely are made for prevention and early detection of cancer for elderly persons. However, cancer incidence and mortality rates are known to rise rapidly with increasing ag...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19881015)62:1+<1823::aid-cncr282

    authors: Yancik R,Kessler L,Yates JW

    更新日期:1988-10-15 00:00:00

  • Results with chemotherapy comprised of cyclophosphamide, doxorubicin, vincristine, and prednisone followed by radiotherapy with or without prechemotherapy surgical debulking for patients with bulky, aggressive lymphoma.

    abstract:BACKGROUND:The authors performed a case-control analysis of local control, progression free survival, and overall survival in patients with Stage I-II aggressive lymphomas measuring > or = 7 cm in greatest dimension who were treated initially with or without surgical debulking: All patients then received cyclophosphami...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.10260

    authors: Wilder RB,Romaguera JE,Tucker SL,Ha CS,Hess MA,Cabanillas F,Cox JD

    更新日期:2002-02-01 00:00:00

  • Erratum: Borderud SP, Li Y, Burkhalter JE, Sheffer CE and Ostroff JS. Electronic cigarette use among patients with cancer: Characteristics of electronic cigarette users and their smoking cessation outcomes. Cancer. doi: 10.1002/ cncr.28811.

    abstract::The authors discovered some errors regarding reference group labels in Table 2. The corrected table is attached. The authors regret these errors. ...

    journal_title:Cancer

    pub_type: 已发布勘误

    doi:10.1002/cncr.29118

    authors:

    更新日期:2015-03-01 00:00:00

  • Acral erythema secondary to high-dose cytosine arabinoside with pain worsened by cyclosporine infusions.

    abstract::Acral erythema after high-dose cytosine arabinoside (Ara-C) has been described as a painful, sharply demarcated, and intense erythema of the palms and soles. This phenomenon occurred and is described in three out of three allogeneic bone marrow transplant (BMT) recipients who received high-dose Ara-C and total-body ir...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890615)63:12<2482::aid-cncr282

    authors: Kampmann KK,Graves T,Rogers SD

    更新日期:1989-06-15 00:00:00

  • Depression in patients with pancreatic carcinoma. Diagnostic and treatment issues.

    abstract:BACKGROUND:Cancer of the pancreas is a highly malignant illness with a very poor prognosis. Unfortunately, there has been little in the way of improvement in prognosis over the past 20 years. It is feared by patients because of its reputation as a deadly and often painful disease. Given these realities, it is not surpr...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/(SICI)1097-0142(19960801)78:3<615::AID-CNC

    authors: Passik SD,Breitbart WS

    更新日期:1996-08-01 00:00:00

  • Quantitative determination of acid-labile DNA in cervical intraepithelial neoplasia.

    abstract::Using a modified Feulgen hydrolysis procedure and integrating microdensitometry, the acid-labile nuclear DNA in exfoliated cervical epithelial cells was quantified in a range of histologically confirmed cervical intraepithelial neoplasia (CIN), invasive cancer, and normal controls. The mean relative optical densities ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19910615)67:12<3104::aid-cncr282

    authors: Partington CK,Sincock AM,Steele SJ

    更新日期:1991-06-15 00:00:00

  • Growth factor expression and proliferation kinetics in periampullary neoplasms in familial adenomatous polyposis.

    abstract:BACKGROUND:Patients with familial adenomatous polyposis develop periampullary adenomas at a high rate. However, little is known regarding the factors that control the growth, the natural history, or the malignant potential of these tumors. METHODS:In this study, the authors systematically evaluated the expression of t...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950715)76:2<187::aid-cncr28207

    authors: Resnick MB,Gallinger S,Wang HH,Odze RD

    更新日期:1995-07-15 00:00:00

  • The impact of mucositis on alpha-hemolytic streptococcal infection in patients undergoing autologous bone marrow transplantation for hematologic malignancies.

    abstract:BACKGROUND:Antibacterial prophylaxis with quinolone antibiotics has resulted in an increase in streptococcal infections among bone marrow transplantation (BMT) recipients with myelosuppression. Oral ulceration (mucositis), which frequently occurs as a consequence of chemotherapy, has been implicated as a significant po...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Ruescher TJ,Sodeifi A,Scrivani SJ,Kaban LB,Sonis ST

    更新日期:1998-06-01 00:00:00

  • Variation in quality of care among older men with localized prostate cancer.

    abstract:BACKGROUND:The objective of this study was to assess the racial and ethnic disparities in outcomes and their association with process-of-care measures for elderly Medicare recipients with localized prostate cancer. METHODS:The Surveillance, Epidemiology, and End Results-Medicare databases for the period from 1995 to 2...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.25812

    authors: Jayadevappa R,Chhatre S,Johnson JC,Malkowicz SB

    更新日期:2011-06-01 00:00:00

  • Malignant schwannoma of the clitoris in a 1-year-old child.

    abstract::A 1-year-old infant with von Recklinghausen's neurofibromatosis was seen because of increasing clitoral enlargement over a 7-month period. The mother, who also had neurofibromatosis, was treated 2 years beforehand for an acoustic neuroma. The child was treated by radical clitorectomy. Pathologic examination revealed m...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890601)63:11<2216::aid-cncr282

    authors: Thomas WJ,Bevan HE,Hooper DG,Downey EJ

    更新日期:1989-06-01 00:00:00

  • Do hormones cause breast cancer?

    abstract::The evidence that various endogenous and exogenous sex hormones play a role in the etiology of breast cancer is reviewed. It is hypothesized that prolonged exposure to normal levels of ovarian estrogens and cyclic progesterone resulting from early menarche and late menopause, and primarily willful nulliparity and late...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19840201)53:3+<595::aid-cncr2820

    authors: Thomas DB

    更新日期:1984-02-01 00:00:00

  • Response to 5-azacytidine in patients with refractory acute nonlymphocytic leukemia and association with chromosome findings.

    abstract::Fifteen patients with acute nonlymphocytic leukemia (ANLL) who either had a relapse after a previous complete remission (nine patients) or progressive disease after initial induction attempts with combination chemotherapy (six patients) were treated with 5-azacytidine. Five patients (33%) achieved a complete remission...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19820601)49:11<2222::aid-cncr282

    authors: Larson RA,Sweet DL,Golomb HM,Testa JR,Rowley JD

    更新日期:1982-06-01 00:00:00

  • Efficacy of follow-up bone scans in carcinoma of the prostate.

    abstract::Three hundred fifteen radioisotopic bone scans ranging from initial scan only to nine scans per patient, performed on 114 patients with adenocarcinoma of the prostate between 1979 and 1984, were reviewed. Seventeen patients had positive scans, ten on initial scan and seven at follow-up. Nine patients had bone pain at ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880615)61:12<2453::aid-cncr282

    authors: Corrie D,Timmons JH,Bauman JM,Thompson IM

    更新日期:1988-06-15 00:00:00

  • Expression of alpha-3/4-monofucosylated polylactosaminoglycan epitope, as defined by monoclonal antibody FW6, is a marker of the colorectal adenoma-carcinoma sequence.

    abstract:BACKGROUND:The expression of a distinct alpha-3/4-monofucosylated polylactosaminoglycan epitope, which is detected by monoclonal antibody FW6, was investigated by comparative immunohistochemical analysis of colorectal tissue specimens exhibiting different grades of premalignant and malignant transformation. The presenc...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19950915)76:6<954::aid-cncr28207

    authors: Baldus SE,Vierbuchen M,Hanisch FG,Schwonzen M,Fischer R

    更新日期:1995-09-15 00:00:00

  • An unusual presentation of a large tumor coexisting with an unusually high nonspecific immune responsiveness. A case report.

    abstract::The authors present the case of a 40-year-old white man with an obstructing laryngeal mass. Despite considerable tumor size, results of repeated biopsies revealed widespread carcinoma in situ with chronic inflammation within the subcutaneous tissues, and only after extensive endoscopic "debulking" of the mass was a sm...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850801)56:3<490::aid-cncr28205

    authors: Eskinazi DP,Mihail R,Dichtel WG

    更新日期:1985-08-01 00:00:00

  • Protease inhibitors and carcinoma of the esophagus.

    abstract:BACKGROUND:Squamous cell carcinoma of the esophagus is endemic in parts of South Africa. Previous case-control studies have shown many associations but no clear etiologic pathway has been established. METHODS:A case-control study of dietary and social factors was performed for 130 patient/control pairs matched for age...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Sammon AM

    更新日期:1998-08-01 00:00:00

  • Government support of cancer research and cancer care health benefits.

    abstract::As the federal government struggles to meet ever-growing budgetary constraints, the need for research into the causes of and potential therapies for treating cancer demands the urgent attention of Congressional leaders. This will require innovative, cost-effective approaches to address the unique needs of cancer resea...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931101)72:9+<2859::aid-cncr282

    authors: Mack C

    更新日期:1993-11-01 00:00:00

  • Cytologic results of fine-needle aspiration biopsies of the central nervous system.

    abstract::The cytologic results of 34 fine-needle aspiration (FNA) biopsies of the central nervous system (CNS) are reported. There were 31 intraoperative biopsies performed at the time of craniotomy. All the cases were diagnosed using direct smear preparations stained with Papanicolaou and Diff-Quik (Harleco, NJ) stains. The s...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860901)58:5<1117::aid-cncr2820

    authors: Silverman JF,Timmons RL,Leonard JR 3rd,Hardy IM,Harris LS,O'Brien K,Norris HT

    更新日期:1986-09-01 00:00:00

  • Sequential identification of factors predicting distant relapse in breast cancer patients treated by conservative surgery.

    abstract:BACKGROUND AND METHODS:Predictors of distant relapse following conservative surgery for breast cancer were studied in a review of 425 women. Five steps of breast cancer patient management were defined in which increasing amounts of information, potentially relevant to prognosis for metastasis-free survival (MFS), were ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930815)72:4<1261::aid-cncr2820

    authors: Tubiana-Hulin M,Le Doussal V,Hacene K,Rouëssé J,Brunet M

    更新日期:1993-08-15 00:00:00

  • Proliferative activity of early gastric cancer measured by in vitro and in vivo bromodeoxyuridine labeling.

    abstract::Forty seven patients with early gastric cancer received a 30-minute intravenous injection of bromodeoxyuridine (BrdU), 1000 mg each 1 hour before laparotomy, to label tumor cells in the S phase. In 13 of 47 patients, specimens obtained by endoscopic biopsy were cultured in vitro at 37 degrees C for 1 hour under three ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19891015)64:8<1665::aid-cncr2820

    authors: Kamata T,Yonemura Y,Sugiyama K,Ooyama S,Kosaka T,Yamaguchi A,Miwa K,Miyazaki I

    更新日期:1989-10-15 00:00:00

  • DNA content and other prognostic features in childhood medulloblastoma. Proposal of a scoring system.

    abstract::The authors reviewed clinical features, surgical extent of resection, histologic parameters, and DNA content in 55 children with medulloblastomas and found that complete or near total resection, absence of tumor dissemination, tumor DNA aneuploidy, and low proliferative index correlated with a favorable clinical outco...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.2820690539

    authors: Schofield DE,Yunis EJ,Geyer JR,Albright AL,Berger MS,Taylor SR

    更新日期:1992-03-01 00:00:00

  • Evaluation of size in prognosis of oral cancer.

    abstract::Greatest surface diameter of a cancer, together with suspicion of regional node metastasis, forms the basis for prognosis through the clinical TNM staging system for many cancers. In oral cancer, however, surface size sometimes fails to correlate, or sometimes inversely correlates, with tumor aggressiveness. To shed l...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860701)58:1<158::aid-cncr28205

    authors: Moore C,Flynn MB,Greenberg RA

    更新日期:1986-07-01 00:00:00

  • Prognostic significance of tumor grade in clinical trials of adjuvant therapy for breast cancer with axillary lymph node metastasis.

    abstract::The prognostic significance of histologic tumor grade has been evaluated in 1537 women entered into the Ludwig Trials I-IV of adjuvant therapy for node-positive breast cancer. Tumor grade was determined on histologic review of primary tumor sections by two central review pathologists using a modification of the Bloom ...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19861215)58:12<2662::aid-cncr282

    authors: Davis BW,Gelber RD,Goldhirsch A,Hartmann WH,Locher GW,Reed R,Golouh R,Säve-Söderbergh J,Holloway L,Russell I

    更新日期:1986-12-15 00:00:00

  • Histogenesis of spontaneous regression of cervical intraepithelial neoplasias.

    abstract::It is justifiable to assume that a spontaneous regression of cervical intraepithelial neoplasia is in progress when pathologic epithelium is replaced by normal epithelium. Very rare histologic pictures of this process are shown. Dysplastic squamous epithelium or intraepithelial carcinomas become detached from their ba...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(1984)54:4<616::aid-cncr282054040

    authors: Bajardi F

    更新日期:1984-08-15 00:00:00

  • Vitiligo autoantibodies are effective against melanoma.

    abstract:BACKGROUND:Vitiligo is a dermatologic disease characterized by local, dispersed, or diffuse white patches on the skin. The disease is defined as an autoimmune disorder because autoantibodies against membranal components of melanocytes are found in the patients' sera. The current study examined whether the autoantibodie...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19931015)72:8<2365::aid-cncr2820

    authors: Fishman P,Azizi E,Shoenfeld Y,Sredni B,Yecheskel G,Ferrone S,Zigelman R,Chaitchik S,Floro S,Djaldetti M

    更新日期:1993-10-15 00:00:00