Production of extracellular matrix-degrading proteinases by primary cultures of human epithelial ovarian carcinoma cells.

abstract：:Oxygen remains one of the most potent sensitizers of mammalian cells yet studied and, most important, it is maximumly sensitizing at physiologic concentrations. There is very good evidence that solid tumors of both experimental animals and man contain hypoxic and viable cells. In experimental animals hyperbaric oxygen...

journal_title：Cancer

authors： Suit HD

更新日期：1968-10-01 00:00:00

abstract：:A 49-year-old white woman with refractory anemia subsequently developed acute myelomonocytic leukemia with paraproteinemia 12 months later. The paraprotein was characterized as immunoglobulin G, type kappa, and the Bence Jones protein as free kappa chains. Further studies, including electron microscopy, cytochemistry,...

journal_title：Cancer

authors： Law IP,Koch FJ,Cannon GB,Herberman RB,Oldham RK

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Typhlitis is increasingly recognized in children undergoing chemotherapy but is poorly characterized. The authors investigated the demographic, clinical, and imaging (ultrasonography and computed tomography [CT] scans) variables related to the diagnosis, risk, and outcome of typhlitis. METHODS:The authors r...

journal_title：Cancer

authors： McCarville MB,Adelman CS,Li C,Xiong X,Furman WL,Razzouk BI,Pui CH,Sandlund JT

更新日期：2005-07-15 00:00:00

abstract：BACKGROUND:The current randomized, controlled, multicenter clinical trial was conducted to investigate the efficacy of concurrent neoadjuvant chemotherapy (NCT) and estrogen deprivation in patients with estrogen receptor (ER)-positive, human epidermal growth factor receptor 2 (HER2)-negative breast cancer. METHODS:Eli...

journal_title：Cancer

authors： Yu KD,Wu SY,Liu GY,Wu J,Di GH,Hu Z,Hou YF,Chen CM,Fan L,Tang LC,Shen ZZ,Wu KJ,Zhuang ZG,Zhang HW,Shao ZM

更新日期：2019-07-01 00:00:00

abstract：:Trichosporon cutaneum is a fungus known to cause superficial nodules over the distal third of hair shafts, mainly scalp hair, and to produce a clinical entity known as piedra. This superficial mycosis occurs mostly in temperate and tropical regions and is rarely seen in North America. Trichosporon cutaneum spesis is d...

journal_title：Cancer

authors： Rivera R,Cangir A

更新日期：1975-09-01 00:00:00

abstract：BACKGROUND:The diagnosis of malignant mesothelioma (MM) in serous effusions is difficult but may be achieved by the application of adjuvant methods. METHODS:The authors cytologically diagnosed 33 effusions as suspicious or positive for MM cells by using DNA-image cytometry (DNA-ICM), immunocytochemistry and AgNOR anal...

journal_title：Cancer

authors： Onofre FB,Onofre AS,Pomjanski N,Buckstegge B,Grote HJ,Böcking A

更新日期：2008-06-25 00:00:00

abstract：:The two cancers specific to women for which substantial research on their relationship to exogenous estrogens has been reported are endometrial cancer and breast cancer. With the former, the link to estrogen use is well established. The estrogen use patterns associated with increased risk of endometrial cancer are cha...

journal_title：Cancer

authors： Hulka BS

更新日期：1987-10-15 00:00:00

abstract：:Forty-three patients with evaluable metastatic breast cancer refractory to hormonal agents and extensive combination chemotherapy including doxorubicin were treated with mitomycin, 20 mg/m2 intravenously every 6 weeks. There were five partial responses (12%) and three minor responses (7%), with a mean time to progress...

journal_title：Cancer

authors： Pasterz RB,Buzdar AU,Hortobagyi GN,Blumenschein GR

更新日期：1985-11-15 00:00:00

abstract：BACKGROUND:Telomerase is commonly recognized as an effective anticancer target. The human telomerase reverse transcriptase (hTERT), the rate-limiting component of telomerase, is expressed in most malignant tumors, but it is not found in most normal somatic cells. Here, we report a real-time and noninvasive method to mo...

journal_title：Cancer

authors： Yu ST,Li C,Lü MH,Liang GP,Li N,Tang XD,Wu YY,Shi CM,Chen L,Li CZ,Cao YL,Fang DC,Yang SM

更新日期：2012-04-01 00:00:00

abstract：:Six patients with Hodgkin's disease (HD) and demonstrable serum antibodies to human immunodeficiency virus (HIV) and two additional patients with HD belonging to HIV-associated high-risk groups but with negative HIV serology were studied. All patients were men and ranged in age from 21 to 45 years. The HIV risk factor...

journal_title：Cancer

authors： Pelstring RJ,Zellmer RB,Sulak LE,Banks PM,Clare N

更新日期：1991-04-01 00:00:00

abstract：:Forty seven patients with early gastric cancer received a 30-minute intravenous injection of bromodeoxyuridine (BrdU), 1000 mg each 1 hour before laparotomy, to label tumor cells in the S phase. In 13 of 47 patients, specimens obtained by endoscopic biopsy were cultured in vitro at 37 degrees C for 1 hour under three ...

journal_title：Cancer

authors： Kamata T,Yonemura Y,Sugiyama K,Ooyama S,Kosaka T,Yamaguchi A,Miwa K,Miyazaki I

更新日期：1989-10-15 00:00:00

abstract：:The pathologic features, clinical presentation and natural history of hepatocellular carcinoma (HCC) developing in the noncirrhotic liver were studied in 61 patients against a background of 63 patients seen concurrently with HCC complicating cirrhosis. Noncirrhotic HCC had a bimodal age distribution, with females pred...

journal_title：Cancer

authors： Smalley SR,Moertel CG,Hilton JF,Weiland LH,Weiand HS,Adson MA,Melton LJ 3rd,Batts K

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Desmoid tumors are mesenchymal nonmetastasizing neoplasms. Although rare in the general population, they are a common extracolonic manifestation of familial adenomatous polyposis (FAP). Because of high tumor recurrence rates, surgery has been less than satisfactory in the treatment of desmoid tumors. In the ...

journal_title：Cancer

authors： Hansmann A,Adolph C,Vogel T,Unger A,Moeslein G

更新日期：2004-02-01 00:00:00

abstract：:The expression of the Thomsen-Friedenreich antigen (T-antigen) in normal and neoplastic urothelium was investigated using paraffin-processed and fresh frozen tissue sections obtained by biopsy from 56 patients. The T-antigen was detected through its binding to the peanut agglutinin (PNA) with two methods: a biotin-avi...

journal_title：Cancer

authors： Limas C,Lange P

更新日期：1986-09-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to characterize insulin receptor (IR) and insulin-like growth factor-1 receptor (IGF-1R) expression in patients with nonsmall cell lung cancer (NSCLC). METHODS:A total of 459 patients who underwent curative resection of NSCLC were studied (median follow-up duration, 4.01 years)...

journal_title：Cancer

authors： Kim JS,Kim ES,Liu D,Lee JJ,Solis L,Behrens C,Lippman SM,Hong WK,Wistuba II,Lee HY

更新日期：2012-05-01 00:00:00

abstract：:Between 1968 and 1985, 28 patients with recurrent gestational trophoblastic disease (GTD) were treated at the Southeastern Regional Trophoblastic Disease Center. Sixteen patients received primary therapy at this center and had recurrence diagnosed by re-elevation of human chorionic gonadotropin (hCG) levels after thre...

journal_title：Cancer

authors： Mutch DG,Soper JT,Babcock CJ,Clarke-Pearson DL,Hammond CB

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:The purpose of this study is to examine changes over time in survival for African American (AA) and white women diagnosed with cervical cancer (CC). METHODS:Surveillance, Epidemiology, and End Results (SEER) Program data from 1985 to 2009 were used for this analysis. Racial differences in survival were eval...

journal_title：Cancer

authors： Rauh-Hain JA,Clemmer JT,Bradford LS,Clark RM,Growdon WB,Goodman A,Boruta DM 2nd,Schorge JO,del Carmen MG

更新日期：2013-10-15 00:00:00

abstract：:The purpose of this study is to evaluate benign and/or malignant thyroid tumors with 201TI thyroid scan. We studied 76 cases of histologically verified thyroid tumors, all seen as cold nodules on the 123I thyroid scan. 201TI thyroid scan was performed 5-15 minutes (early scan) and 3-5 hours (delayed scan) after intrav...

journal_title：Cancer

authors： Ochi H,Sawa H,Fukuda T,Inoue Y,Nakajima H,Masuda Y,Okamura T,Onoyama Y,Sugano S,Ohkita H,Tei Y,Kamino K,Kobayashi Y

更新日期：1982-07-15 00:00:00

abstract：:Data from a hospital-based case-control study between 1985-1990 were used to examine the effects of tobacco, alcohol, asbestos, and other occupational exposures on laryngeal cancer risk in 194 white men with primary cancer of the larynx and 184 age-matched control subjects. A dose-dependent effect for current cigarett...

journal_title：Cancer

authors： Muscat JE,Wynder EL

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:For many childhood cancers, survival is lower among non-Hispanic blacks and Hispanics in comparison with non-Hispanic whites, and this may be attributed to underlying socioeconomic factors. However, prior childhood cancer survival studies have not formally tested for mediation by socioeconomic status (SES). ...

journal_title：Cancer

authors： Kehm RD,Spector LG,Poynter JN,Vock DM,Altekruse SF,Osypuk TL

更新日期：2018-10-15 00:00:00

abstract：:A solitary tumor which by light microscopy was calssified as a neurofibroma was found by electron microscopic study to be composed of parallel, elongate cells with collagen rich intervening matrix. The cells showed thin, polar cytoplasmic processes which extended long distances, frequent junctional complexes between c...

journal_title：Cancer

authors： Lazarus SS,Trombetta LD

更新日期：1978-05-01 00:00:00

abstract：:A case of pancreatoblastoma, arising in the tail of the pancreas with metastases to the right radius, in an 8-year-old boy is reported. The serum alpha-fetoprotein (AFP) level was over 13 times the normal value before surgery, but returned to normal after removal of the primary tumor. Furthermore, AFP was detected in ...

journal_title：Cancer

authors： Iseki M,Suzuki T,Koizumi Y,Hirose M,Laskin WB,Nakazawa S,Ohaki Y

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:A diagnosis of cancer provides a teachable moment in which a physician can counsel or teach the patient. The Cancer and Leukemia Group B hypothesized that this teachable moment could also be used to encourage counseling of the patients' relatives who smoke. The authors' first study sought to determine the fe...

journal_title：Cancer

authors： Schilling A,Conaway MR,Wingate PJ,Atkins JN,Berkowitz IM,Clamon GH,DiFino SM,Vinciguerra V

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:The difficulties adolescents and young adults (AYAs) encounter during a cancer experience may result in a reduction in or absence of empowerment. The aims of the current study were to assess levels of empowerment and associated (demographic, clinical, or psychological) factors and examine the association bet...

journal_title：Cancer

authors： Kaal SEJ,Husson O,van Duivenboden S,Jansen R,Manten-Horst E,Servaes P,Prins JB,van den Berg SW,van der Graaf WTA

更新日期：2017-10-15 00:00:00

abstract：:Although improvements in the management of adults with acute leukemia have lagged behind those seen in the treatment of children, there are clear reasons for optimism. Combination chemotherapy for acute myeloblastic leukemia (AML) and acute lymphoblastic leukemia (ALL) in adults results in complete remissions in 50-85...

journal_title：Cancer

authors： Eyre HJ,Ward JH,Priebat DA

更新日期：1983-06-15 00:00:00

abstract：:Tissue specimens from five patients with rheumatic disease who developed lymphadenopathy were studied by an immunoperoxidase method; available biopsy material was examined for cytoplasmic immunoglobulin determinants. Three patients had follicular hyperplasia of lymph nodes with polyclonal patterns. Two patients with S...

journal_title：Cancer

authors： Humphrey DM,Cortez EA,Spiva DA

更新日期：1982-05-15 00:00:00

abstract：BACKGROUND:The widespread use of anthracycline chemotherapy has contributed to improved outcomes in children with cancer. The most feared complication of the anthracyclines is cardiotoxicity. Routine echocardiographic monitoring typically is used before, during, and after treatment to minimize cardiotoxicity. The ideal...

journal_title：Cancer

authors： Watts RG,George M,Johnson WH Jr

更新日期：2012-04-01 00:00:00

abstract：:One hundred twenty two children with non-Hodgkin's lymphoma were studied from January 1966 to December 1975. The first group (1966-1972) did not receive an uniform treatment. The second group (1973-1975) entered in a G.A.T.L.A. protocol consisting of: vincristine-prednisone plus surgery and/or radiotherapy as inductio...

journal_title：Cancer

authors： Cebrian-Bonesana A,Schvartzman E,Roca-Garcia C,Pependieck C,Sackmann-Muriel S,Ojeda FG,Kvicala R,Pavlovsky S,Lein JM,Penchansky L

更新日期：1978-06-01 00:00:00

abstract：BACKGROUND:p53 plays a critical role in cellular anticancer mechanisms, and has been correlated with second primary malignancy (SPM) development. A common polymorphism in codon 72 of p53 results in an amino acid substitution and could influence p53 function. The authors hypothesized that p53 codon 72 polymorphism may b...

journal_title：Cancer

authors： Li F,Sturgis EM,Chen X,Zafereo ME,Wei Q,Li G

更新日期：2010-05-15 00:00:00

abstract：BACKGROUND:Cisplatin has been reported to enhance the cell-killing effect of radiation. The current study was conducted to evaluate the efficacy and toxicity of radiotherapy combined with cisplatin in patients with locally advanced pancreatic carcinoma. METHODS:Forty-one patients with pancreatic carcinoma that was unr...

journal_title：Cancer

authors： Okusaka T,Okada S,Tokuuye K,Wakasugi H,Saisho H,Ishikawa O,Matsuno S,Sato T,Sato K,Non-surgical Treatment Group for Pancreatic Cancer in Japan.

更新日期：2001-04-01 00:00:00