Abstract:
:Tissue specimens from five patients with rheumatic disease who developed lymphadenopathy were studied by an immunoperoxidase method; available biopsy material was examined for cytoplasmic immunoglobulin determinants. Three patients had follicular hyperplasia of lymph nodes with polyclonal patterns. Two patients with Sjogren's syndrome had monoclonal patterns; both of these patients subsequently developed lymphoma with similar monoclonal patterns. Implications of the monoclonal patterns with regard to the biology of these lymphoproliferative disorders are discussed.
journal_name
Cancerjournal_title
Cancerauthors
Humphrey DM,Cortez EA,Spiva DAdoi
10.1002/1097-0142(19820515)49:10<2049::aid-cncr282subject
Has Abstractpub_date
1982-05-15 00:00:00pages
2049-69issue
10eissn
0008-543Xissn
1097-0142journal_volume
49pub_type
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