Sites of primary malignancies in patients presenting with cerebral metastases. A review of 120 cases.

Abstract:

:A retrospective study is reported of 120 consecutive cases of patients presenting with brain metastases as the primary sign of their malignancy. Primary site was found in 62 patients (53 while alive and 9 at postmortem examination) and remained unknown in 58. Lung was the most frequent primary site (45% of known sites), and digestive malignancies were surprisingly the second most frequent primary site (19% of known sites), whereas breast was found in less than 5%. When primary site was disclosed, in 85% it was after history, clinical exam, chest x-ray, and pathologic findings. Survival was almost identical in both known and unknown primary sites: 54% versus 44% at 6 months, 20% versus 16% at 1 year, and 6% versus 5% at 2 years. It was concluded that extensive evaluations to identify primary sites do not appear to be rational in patients presenting with brain metastases.

journal_name

Cancer

journal_title

Cancer

authors

Le Chevalier T,Smith FP,Caille P,Constans JP,Rouesse JG

doi

10.1002/1097-0142(19850815)56:4<880::aid-cncr28205

subject

Has Abstract

pub_date

1985-08-15 00:00:00

pages

880-2

issue

4

eissn

0008-543X

issn

1097-0142

journal_volume

56

pub_type

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