Cardiovascular disease in survivors of hematopoietic cell transplantation.

Abstract:

:Hematopoietic cell transplantation (HCT) is increasingly offered as a curative option for many patients with hematologic malignancies. Improvements in HCT strategies and supportive care have resulted in a growing number of long-term survivors. However, these survivors are at an increased risk of developing long-term debilitating chronic health conditions, including premature cardiovascular disease. These complications are more common than in the general population, and there are well-described associations between therapeutic exposures, traditional cardiovascular risk factors, and subsequent cardiovascular disease risk. The authors present herein an overview of the current state of knowledge regarding pathogenesis and risk factors for some of the more commonly occurring cardiovascular complications after HCT, highlighting existing surveillance recommendations and future directions for research to minimize cardiovascular morbidity in these survivors.

journal_name

Cancer

journal_title

Cancer

authors

Armenian SH,Chow EJ

doi

10.1002/cncr.28444

subject

Has Abstract

pub_date

2014-02-15 00:00:00

pages

469-79

issue

4

eissn

0008-543X

issn

1097-0142

journal_volume

120

pub_type

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