A study of cyproheptadine in the treatment of metastatic carcinoid tumor and the malignant carcinoid syndrome.

abstract：:Review of 61 surgically resected small hepatocellular carcinomas (HCC) less than or equal to 3 cm in diameter yielded a simple gross classification system of five types based on tumor shape, which is highly correlated with microscopic and clinical features, including prognosis. Type 1 (single nodular type) tumors (n =...

journal_title：Cancer

authors： Kanai T,Hirohashi S,Upton MP,Noguchi M,Kishi K,Makuuchi M,Yamasaki S,Hasegawa H,Takayasu K,Moriyama N

更新日期：1987-08-15 00:00:00

abstract：BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...

journal_title：Cancer

authors： Baddoura FK,Unger ER,Mufarrij A,Nassar VH,Zaki SR

更新日期：1994-09-15 00:00:00

abstract：BACKGROUND:The authors evaluated the efficacy of adjuvant chemotherapy with 5-fluorouracil (5-FU) plus doxorubicin in gastric carcinoma after D2-3 curative resection. They also evaluated the effect of dose-related factors (delivered total dose/m(2), actual dose intensity [ADI], relative dose intensity [RDI]) of this re...

journal_title：Cancer

authors： Jeung HC,Rha SY,Noh SH,Min JS,Kim BS,Chung HC

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:The current study reports on the significance of cervical smears identified as atypical squamous cells of undetermined significance (ASCUS) in the largest Asian screening population to date. METHODS:From January 1998 to December 1999, 190,000 cervical smears were evaluated by the cervical cytology laborator...

journal_title：Cancer

authors： Cheung AN,Szeto EF,Ng KM,Fong KW,Yeung AC,Tsun OK,Khoo US,Chan KY,Ng AW

更新日期：2004-04-25 00:00:00

abstract：:Age-specific incidence curves, cumulative rates, and relative risks were estimated for selected malignancies among male veterans utilizing the Veterans Administration (VA) medical system during 1970 to 1982. Relative risks for malignant tumors of the lung, bronchus, larynx, oral cavity, and esophagus in males using VA...

journal_title：Cancer

authors： Harris RE,Hebert JR,Wynder EL

更新日期：1989-09-01 00:00:00

abstract：:The incidence of gastric cancer has declined markedly in Finland during the last 4 decades. To document the changes caused by that in the ratio of the intestinal type (IT) to the diffuse type (DT) of gastric carcinoma we compared the 367 cases diagnosed from southwestern Finland at the Department of Pathology, Turku U...

journal_title：Cancer

authors： Laurén PA,Nevalainen TJ

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:The authors assessed the prognostic significance of abnormal cyclin dependent kinase inhibitor (CDKI) expression in adenocarcinomas of the uterine cervix. METHODS:Population-based, archival material from patients with International Federation of Gynecology and Obstetrics (FIGO) Stage I and II cervical adeno...

journal_title：Cancer

authors： Alfsen GC,Reed W,Sandstad B,Kristensen GB,Abeler VM

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Surveillance, Epidemiology, and End Results (SEER) data for the years 1973-1992 documented that patients age < 50 years presented with more advanced disease. Because of the increase in the incidence rate of lung adenocarcinoma in the past few decades and the presentation of more advanced disease in young pat...

journal_title：Cancer

authors： Liu NS,Spitz MR,Kemp BL,Cooksley C,Fossella FV,Lee JS,Hong WK,Khuri FR

更新日期：2000-04-15 00:00:00

abstract：BACKGROUND:Although it is believed that p53 suppressor gene mutations, compared with mutations in the K-ras oncogene, occur at a later stage of colorectal tumorigenesis, the distribution of these genetic alterations at an early stage remains poorly characterized. METHODS:The authors analyzed the immunoreactivity for p...

journal_title：Cancer

authors： Hosaka S,Aoki Y,Akamatsu T,Nakamura N,Hosaka N,Kiyosawa K

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:A National Institutes of Health (NIH) Consensus Development Conference on the treatment of patients with early stage invasive breast carcinoma, held in June 1990, recommended breast conservation therapy for the majority of women with Stage I or II breast carcinoma. The authors evaluated the national use of b...

journal_title：Cancer

authors： Lazovich D,Solomon CC,Thomas DB,Moe RE,White E

更新日期：1999-08-15 00:00:00

abstract：:Two-hundred-four patients with previously untreated adenocarcinoma of rectum, rectosigmoid, and sigmoid colon were retrospectively evaluated to determine patterns of recurrence following curative resection. Seventy-eight (38%) subsequently developed recurrent disease. Of these, 40% (31/78) presented with local recurre...

journal_title：Cancer

authors： Rao AR,Kagan AR,Chan PM,Gilbert HA,Nussbaum H,Hintz BL

更新日期：1981-09-15 00:00:00

abstract：BACKGROUND:The objective of this study was to determine the clinical characteristics, treatment response, and frequency of p53 overexpression in Ashkenazi Jewish women with hereditary ovarian carcinoma. METHODS:Seventy-one Jewish women with epithelial ovarian carcinoma (EOC) were tested for the three BRCA founder muta...

journal_title：Cancer

authors： Cass I,Baldwin RL,Varkey T,Moslehi R,Narod SA,Karlan BY

更新日期：2003-05-01 00:00:00

abstract：:Breast fluid was collected from 244 nonlactating Finnish women with no known breast disease and analyzed with respect to various epidemiologic and hormonal parameters commonly associated with breast cancer risk. The data obtained permit characterization of women with breast secretory ability and provide fundamental in...

journal_title：Cancer

authors： Wynder EL,Hill P,Laakso K,Littner R,Kettunen K

更新日期：1981-03-15 00:00:00

abstract：:In a 3 1/2 year cytogenetic study of 107 leukemia patients diagnosed in childhood and adloescence, 8 presented with chronic myelogenous leukemia (CML). Seven of the 8 had chromosomal abnormalities. Six had the Ph1 chromosome; 5 had the usual 9;22 translocation. Two patients had involvement with chromosome 15; one had ...

journal_title：Cancer

authors： Hays T,Morse H,Peakman D,Rose B,Robinson A

更新日期：1979-07-01 00:00:00

abstract：BACKGROUND:Bortezomib has preclinical and clinical in B-cell lymphomas, both alone and in combination with other agents. A phase 1 evaluation was conducted of bortezomib with rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with untreated diffuse large B-cell lymphoma (DLBC...

journal_title：Cancer

authors： Furman RR,Martin P,Ruan J,Cheung YK,Vose JM,LaCasce AS,Elstrom R,Coleman M,Leonard JP

更新日期：2010-12-01 00:00:00

abstract：:Estrogen and progesterone receptors (ER/PR) were measured in primary tumors and metastases of 397 breast cancer patients. Survival following mastectomy was significantly longer in patients with ER and PR positive tumors, as was survival after first recurrence. The prognostic value of ER and PR was compared with such c...

journal_title：Cancer

authors： Alanko A,Heinonen E,Scheinin T,Tolppanen EM,Vihko R

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND:During the last two decades, a rising incidence of adenocarcinoma of the esophagus has been observed in the Western world. The prognostic relevance of tumor-biological factors, such as DNA ploidy or c-erbB-2 overexpression, for overall survival following complete resection is still unknown. METHODS:In a ret...

journal_title：Cancer

authors： Nakamura T,Nekarda H,Hoelscher AH,Bollschweiler E,Harbeck N,Becker K,Siewert JR,Harbec N corrected to Harbeck N

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:In the AFFIRM trial, enzalutamide significantly increased overall survival (OS) for men with metastatic castration-resistant prostate cancer (mCRPC) after chemotherapy versus placebo and significantly decreased prostate-specific antigen (PSA) levels. The goal of this post hoc analysis was to associate levels...

journal_title：Cancer

authors： Armstrong AJ,Saad F,Phung,Dmuchowski C,Shore ND,Fizazi K,Hirmand M,Forer D,Scher HI,Bono J

更新日期：2017-06-15 00:00:00

abstract：:Carboplatin (diammine [1,1-cyclobutanedicarboxylate(2-)-O,o']platinum) is a second generation platinum coordination complex. It has a spectrum of activity that is similar to that of cisplatin and is less nephrotoxic and emetogenic in experimental animals. Fifty-two 30-minute infusions of carboplatin were given to 20 e...

journal_title：Cancer

authors： Koeller JM,Trump DL,Tutsch KD,Earhart RH,Davis TE,Tormey DC

更新日期：1986-01-15 00:00:00

abstract：:Two female patients with desmoid tumors (aggressive fibromatosis) showed tumor regression after endocrine therapy. In one patient, tumor response to tamoxifen has been maintained over several years of treatment. In the second patient, who had inoperable mesenteric fibromatosis, the tumor progressed on tamoxifen but re...

journal_title：Cancer

authors： Wilcken N,Tattersall MH

更新日期：1991-09-15 00:00:00

abstract：:Fifty-one patients with metastatic breast cancer were randomly allocated to receive either a four drug combination consisting of cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP), or a combination of vincristine, Adriamycin, and cyclophosphamide (VAC) with cross-over on relapse. Objective responses...

journal_title：Cancer

authors： Carmo-Pereira J,Costa FO,Henriques E

更新日期：1981-10-01 00:00:00

abstract：:During the past eight years, 137 patients with mycosis fungoides were given total skin electron beam therapy (TSEB) using 2.5 to 4 MeV electrons. A single treatment delivers 400 rads to the entire skin surface, and patients are treated once a week for six to eight consecutive weeks. All have been followed for a median...

journal_title：Cancer

authors： Nisce LZ,Safai B,Kim JH

更新日期：1981-03-01 00:00:00

abstract：:A 22-micron glass microsphere called TheraSphere (Theragenics Corp., Atlanta, GA) has been developed in which yttrium 89 oxide is incorporated into the glass matrix and is activated by neutron bombardment to form the beta-emitting isotope yttrium 90 (Y 90) before using the spheres as radiotherapeutic vehicles. The inj...

journal_title：Cancer

authors： Wollner I,Knutsen C,Smith P,Prieskorn D,Chrisp C,Andrews J,Juni J,Warber S,Klevering J,Crudup J

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:The authors tested the hypothesis that the metabolic syndrome (> or =3 of the following components: high blood pressure, increased waist circumference, hypertriglyceridemia, low levels of high-density lipoprotein cholesterol, or diabetes/hyperglycemia) is a risk factor for colorectal cancer. METHODS:Data fr...

journal_title：Cancer

authors： Ahmed RL,Schmitz KH,Anderson KE,Rosamond WD,Folsom AR

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Parathyroid hormone-related protein (PTHrP) is the predominant cause of humoral hypercalcemia of malignancy (HHM). METHODS:Using a PTHrP-specific monoclonal antibody (MoAb), 4B3, the authors investigated the immunohistochemical localization of PTHrP in formalin-fixed and paraffin-embedded sections of normal...

journal_title：Cancer

authors： Gotoh A,Kitazawa S,Mizuno Y,Takenaka A,Arakawa S,Matsumoto O,Kitazawa R,Fujimori T,Maeda S,Kamidono S

更新日期：1993-05-01 00:00:00

abstract：:One hundred fifty-six evaluable patients with metastatic breast cancer were treated with vincristine, Adriamycin and cyclophosphamide alternating at fixed intervals with 5-FU and methotrexate. Immunotherapy with BCG or MER-BCG was administered to all patients in two consecutive treatment programs. Overall objective re...

journal_title：Cancer

authors： Blumenschein GR,Hortobagyi GN,Richman SP,Gutterman JU,Tashima CK,Buzdar AU,Burgess MA,Livingston RB,Hersh EM

更新日期：1980-02-15 00:00:00

abstract：:Two hundred seventy-nine consecutive patients with Stage II osteogenic sarcoma of the appendicular skeleton treated between 1976 and 1986 were studied to identify predictors of long-term survival. Survival was 77% and 73% at 5 and 10 years, respectively, with continuously disease-free survival being 70% and 69%. On un...

journal_title：Cancer

authors： Glasser DB,Lane JM,Huvos AG,Marcove RC,Rosen G

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:The objectives of this study were to evaluate survival among current smokers, former smokers, and never smokers who are diagnosed with non-small cell lung cancer (NSCLC). METHODS:The study included patients who participated in the National Comprehensive Cancer Network's NSCLC Database Project. Current, form...

journal_title：Cancer

authors： Ferketich AK,Niland JC,Mamet R,Zornosa C,D'Amico TA,Ettinger DS,Kalemkerian GP,Pisters KM,Reid ME,Otterson GA

更新日期：2013-02-15 00:00:00

abstract：BACKGROUND:Melanoma is the most lethal form of skin cancer, with an estimated 68,130 new cases and 8700 deaths in the United States in 2010. The increasing incidence and high death rate associated with metastatic disease support the need to focus on prevention. The authors used data from the Women's Health Initiative (...

journal_title：Cancer

authors： Jagtap D,Rosenberg CA,Martin LW,Pettinger M,Khandekar J,Lane D,Ockene I,Simon MS

更新日期：2012-10-15 00:00:00

abstract：:Two siblings succumbed to glioblastoma multiforme, associated with hepatic focal nodular hyperplasia and cafe-au-lait spots. One sibling had syndactyly and multiple colonic polyps, while the other had an angiomatous malformation in the brain. Their mother died of myasthenia gravis. The findings suggest a hamartomatous...

journal_title：Cancer

authors： Everson RB,Fraumeni JF Jr

更新日期：1976-07-01 00:00:00