Chemotherapy of advanced breast cancer: a randomized trial of vincristine, Adriamycin, and cyclophosphamide (VAC) versus cyclophosphamide, methotrexate, 5-fluorouracil, and prednisone (CMFP).

abstract：BACKGROUND:Ewing sarcoma family of tumors (ESFT) of bone is extremely rare in Japan. The objectives of the current study were to assess the clinical outcome and prognostic factors of patients with ESFT of bone in Japan and to compare them between Euro-American and Japanese populations. METHODS:The authors conducted a ...

journal_title：Cancer

authors： Obata H,Ueda T,Kawai A,Ishii T,Ozaki T,Abe S,Tanaka K,Tsuchiya H,Matsumine A,Yabe H,Japanese Musculoskeletal Oncology Group.

更新日期：2007-02-15 00:00:00

abstract：:Few studies have incorporated high-dose methotrexate (MTX) with leucovorin rescue in the treatment of small cell lung cancer (SCLC). Potentially therapeutic levels of MTX can be achieved in the central nervous system (CNS) by systemic administration of high doses of this drug. Utilizing a combination chemotherapy prog...

journal_title：Cancer

authors： Neijstrom ES,Capizzi RL,Rudnick SA,Kirsch M,Delaney D,Kahn L,Lipper S,Carney C

更新日期：1983-03-15 00:00:00

abstract：BACKGROUND:Although cervical carcinoma incidence and mortality rates have declined in the U.S. greatly since the introduction of the Papanicolaou smear, this decline has not been uniform for all histologic subtypes. Therefore, the authors assessed the differential incidence rates of squamous cell carcinoma (SCC) and ad...

journal_title：Cancer

authors： Wang SS,Sherman ME,Hildesheim A,Lacey JV Jr,Devesa S

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Although almost half of all incidents of breast carcinoma occur in women age > or = 65 years, not enough is known about appropriate care for patients in this age group. The objective of the current study was to evaluate the role of breast conservation therapy in the management of breast carcinoma in women ag...

journal_title：Cancer

authors： Vlastos G,Mirza NQ,Meric F,Hunt KK,Kuerer HM,Ames FC,Ross MI,Buchholz TA,Hortobagyi GN,Singletary SE

更新日期：2001-09-01 00:00:00

abstract：:Cancer is among the leading causes of morbidity and mortality in the Western world. Despite recent advances, most therapeutic approaches fail to eradicate the entire neoplastic clone. The remaining cells often develop metastasis and/or recurrences and therefore may represent attractive targets of therapy. A new exciti...

journal_title：Cancer

authors： Schulenburg A,Ulrich-Pur H,Thurnher D,Erovic B,Florian S,Sperr WR,Kalhs P,Marian B,Wrba F,Zielinski CC,Valent P

更新日期：2006-11-15 00:00:00

abstract：BACKGROUND:Coagulopathies often are associated with malignant tumors. The pathogenesis of these complications in cancer is not clear. Host inflammatory (monocyte/macrophage) cell-mediated triggering of clotting activation has been suggested. METHODS:The objective of this study was to evaluate the role of neutrophil-de...

journal_title：Cancer

authors： Gabazza E,Taguchi O,Yamakami T,Machishi M,Ibata H,Suzuki S

更新日期：1993-10-01 00:00:00

abstract：:A series of 27 typical Krukenberg tumors of the ovary were analyzed. By definition, all examples were characterized by the presence of mucinous signet-ring carcinoma cells within a cellular, nonneoplastic ovarian stroma. The patients' ages ranged from 20-70 years; almost one-half were 40 years of age or younger. A pri...

journal_title：Cancer

authors： Holtz F,Hart WR

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND:The objective of the current study was to assess the efficacy of combination therapy with fludarabine and mitoxantrone in patients with B-cell chronic lymphocytic leukemia (CLL). METHODS:Eighty-eight patients were treated with fludarabine 30 mg/m(2) intravenously daily for 3 days and mitoxantrone 10 mg/m(2)...

journal_title：Cancer

authors： Tsimberidou AM,Keating MJ,Giles FJ,Wierda WG,Ferrajoli A,Lerner S,Beran M,Andreeff M,Kantarjian HM,O'Brien S

更新日期：2004-06-15 00:00:00

abstract：:The National Wilms' Tumor Study (NWTS) was initiated in 1969. One of its objectives was to modulate treatments according to risk factors to minimize the number and severity of treatment-related short-term and long-term iatrogenic complications. The NWTS has therefore incorporated a Long Term Follow-up Study (LTFS) wit...

journal_title：Cancer

authors： Evans AE,Norkool P,Evans I,Breslow N,D'Angio GJ

更新日期：1991-01-15 00:00:00

abstract：:A 30-year-old man underwent orchiectomy in 1962 for a testicular carcinoma composed of choriocarcinomatous and teratocarcinomatous elements. Bilateral pulmonary metastases regressed completely on combination chemotherapy. However, a cerebral metastasis developed in 1963 and caused severe neurologic signs. At craniotom...

journal_title：Cancer

authors： Stolinsky DC

更新日期：1981-03-01 00:00:00

abstract：BACKGROUND:Some patients with chronic myeloid leukemia (CML) have a history of previous malignancies. To the authors' knowledge, outcomes for CML diagnosed in these patients have not been well described. The current study was conducted to determine the outcome of patients with CML and a history of prior malignancies. ...

journal_title：Cancer

authors： Koller PB,Kantarjian HM,Nogueras-Gonzalez GM,Jabbour E,Verstovsek S,Borthakur G,Estrov Z,Wierda WG,Garcia-Manero G,Ferrajoli A,Ravandi F,O'Brien SM,Cortes JE

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) are KIT-positive mesenchymal tumors of the gastrointestinal tract that are driven by activated KIT-signalling or platelet-derived growth factor receptor-alpha (PDFGRA) signaling. These tumors most commonly occur in the stomach and small intestine and encompass a clinic...

journal_title：Cancer

authors： Miettinen M,Kraszewska E,Sobin LH,Lasota J

更新日期：2008-02-01 00:00:00

abstract：:A hospital-based case-control study was done to examine the hypothesis that persons with a family history of multiple myeloma (MM) or other cancers are at increased risk of multiple myeloma. Study members were 439 cases of multiple myeloma and 1317 matched controls seen at the Duke University Medical Center. Only 3 ca...

journal_title：Cancer

authors： Bourguet CC,Grufferman S,Delzell E,DeLong ER,Cohen HJ

更新日期：1985-10-15 00:00:00

abstract：:Seventy-eight patients with metastatic cancer to the lungs underwent flexible fiberoptic bronchoscopy for diagnosis. The patients were divided into two groups by presenting radiographic pattern as: (I) diffuse linear interstitial infiltrations (55 patients); and (II) localized or multiple nodular opacities (23 patient...

journal_title：Cancer

authors： Chuang MT,Padilla ML,Teirstein AS

更新日期：1983-11-15 00:00:00

abstract：BACKGROUND:Caveolin-1 plays a regulatory role in several signaling pathways. Recently caveolin-1 was identified as a metastasis-related gene in prostate carcinoma. However, the clinical impact of caveolin-1 expression in esophageal carcinoma remains unknown. METHODS:One hundred thirty surgical specimens of esophageal ...

journal_title：Cancer

authors： Kato K,Hida Y,Miyamoto M,Hashida H,Shinohara T,Itoh T,Okushiba S,Kondo S,Katoh H

更新日期：2002-02-15 00:00:00

abstract：BACKGROUND:Because of morphologic similarities, the differential diagnosis of granulocytic sarcoma (GS) in fine-needle aspiration (FNA) specimens includes non-Hodgkin or Hodgkin lymphoma, extramedullary hematopoiesis, poorly differentiated carcinoma, and infection. METHODS:Twenty-six FNAs and 1 pleural effusion fluid ...

journal_title：Cancer

authors： Suh YK,Shin HJ

更新日期：2000-12-25 00:00:00

abstract：:A prospective study of computerized tomography (CT) of the liver using a liver contrast agent compared to conventional CT was undertaken. CT scanning without contrast agents (NC-CT), CT with water-soluble contrast (WSC-CT), and CT with ethiodized oil emulsion (EOE-CT) were performed on patients with possible or probab...

journal_title：Cancer

authors： Sugarbaker PH,Vermess M,Doppman JL,Miller DL,Simon R

更新日期：1984-10-15 00:00:00

abstract：BACKGROUND:The American Joint Committee on Cancer (AJCC) 7th edition introduced major changes in the staging of lung cancer, including the tumor (T), node (N), metastasis (M)-TNM-system and new stage/prognostic site-specific factors (SSFs), collected under the Collaborative Stage Version 2 (CSv2) Data Collection System...

journal_title：Cancer

authors： Chen VW,Ruiz BA,Hsieh MC,Wu XC,Ries LA,Lewis DR

更新日期：2014-12-01 00:00:00

abstract：:The potential of using a blood test enumerating oncofetal ferritin-bearing lymphocytes (FBL) as a biomarker for early breast cancer was further explored. Nine hundred women attending a high-risk breast cancer clinic and 2500 normal-risk women were physically examined and their blood drawn for FBL determination using a...

journal_title：Cancer

authors： Moroz C,Kahn M,Ron E,Luria H,Chaimoff C

更新日期：1989-08-01 00:00:00

abstract：:Cancer tissues from 30 patients with squamous cell carcinoma of the oral cavity were examined immunohistopathologically as to the responsiveness of the host against its own cancer cells in both biopsy and surgically resected specimens from the same patients. Subpopulations of the infiltrating lymphocytes in cancer tis...

journal_title：Cancer

authors： Hiratsuka H,Imamura M,Ishii Y,Kohama G,Kikuchi K

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:The prognostic impact of DNA mismatch repair (MMR) status remains controversial in patients with stage III colon cancer who are treated with adjuvant chemotherapy (AC). The aim of this study was to evaluate the survival outcome of AC in deficient mismatch repair (dMMR)/microsatellite instable (MSI) stage III...

journal_title：Cancer

authors： Shaib WL,Zakka KM,Jiang R,Yan M,Alese OB,Akce M,Wu C,Behera M,El-Rayes BF

更新日期：2020-09-15 00:00:00

abstract：:Encouraging results from several recent trials have increased interest in the potential of chemoprevention in reducing the incidence of cancer. Treatment with 13-cis-retinoic acid has reversed oral leukoplakia, a premalignant lesion, and prevented the development of second primary carcinomas of the head and neck. Tamo...

journal_title：Cancer

authors： Itri LM

更新日期：1993-12-01 00:00:00

abstract：:Traditional therapy for malignant pleural effusions includes thoracentesis or tube drainage with instillation of irritants to achieve pleurodesis. This can require a lengthy hospitalization, causes pain and discomfort, and has an appreciable failure rate. Because of these drawbacks, the authors used a shunting device ...

journal_title：Cancer

authors： Little AG,Ferguson MK,Golomb HM,Hoffman PC,Vogelzang NJ,Skinner DB

更新日期：1986-12-15 00:00:00

abstract：:To evaluate the frequency, etiology, and outcome of diffuse interstitial pneumonitis after treatment of children with Stage IV (favorable histologic type) Wilms' tumor using whole-lung and abdominal radiation therapy, and combination chemotherapy, all cases reported in such patients entered on National Wilms' Tumor St...

journal_title：Cancer

authors： Green DM,Finklestein JZ,Tefft ME,Norkool P

更新日期：1989-02-01 00:00:00

abstract：:Seventeen patients were given DTIC, 200 mg/m2/day in five-day courses every four to six weeks. In four patients (stage II) treated on an adjuvant basis, tumor recurrence has been verified in three. Four of the palliatively treated patients were also given DTIC by regional intra-arterial infusion with minimal positive ...

journal_title：Cancer

authors： Jönsson PE,Agrup G,Arnbjörnsson E,Hafström L,Rorsman H

更新日期：1980-01-15 00:00:00

abstract：:Systemic aspergillosis is encountered with increasing prevalence in immunocompromised patients undergoing chemotherapy. The current communication describes the clinical and postmortem findings in three leukemic patients who developed myocardial infarction secondary to Aspergillus embolization of the coronary arteries....

journal_title：Cancer

authors： Andersson BS,Luna MA,McCredie KB

更新日期：1986-11-01 00:00:00

abstract：:Renal cell carcinoma is the most common renal neoplasm associated with pregnancy. The most common presenting symptoms are pain and a palpable mass. Although renal neoplasms in pregnancy are rare, the pregnancy demands special consideration in the methods of diagnostic evaluation. The relationship between renal cell ca...

journal_title：Cancer

authors： Walker JL,Knight EL

更新日期：1986-11-15 00:00:00

abstract：:The livers of 345 autopsy cases of chronic liver disease were examined for macroregenerative nodule (MRN), a large nodular lesion more than 10 mm in diameter. A total of 86 lesions of MRN was found in 49 cases (14.2%): 32 were from 191 cases of hepatocellular carcinoma (HCC), 16 were from 148 cases of cirrhosis only, ...

journal_title：Cancer

authors： Furuya K,Nakamura M,Yamamoto Y,Togei K,Otsuka H

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Portal vein thrombosis (PVT) is a common complication in patients with advanced-stage hepatocellular carcinoma (HCC). The authors evaluated the impact of radiotherapy (RT) for PVT of HCC and analyzed the dose-response relation between RT and PVT. METHODS:Between March 1995 and December 2003, 59 patients dia...

journal_title：Cancer

authors： Kim DY,Park W,Lim DH,Lee JH,Yoo BC,Paik SW,Kho KC,Kim TH,Ahn YC,Huh SJ

更新日期：2005-06-01 00:00:00

abstract：:From 1977, 29 patients with inoperable non-small cell lung carcinoma due to locally far-advanced disease underwent lung resection after receiving two to eight courses of chemotherapy. After the surgery was performed, three additional courses of chemotherapy were given. The overall median survival from onset of the che...

journal_title：Cancer

authors： Takita H,Regal AM,Antkowiak JG,Rao UN,Botsoglou NK,Lane WW

更新日期：1986-02-01 00:00:00