Multiple myeloma and family history of cancer. A case-control study.

abstract：BACKGROUND:To explore the potential role of infiltrating benign B cells in classic Hodgkin disease (HD) lesions in supporting the survival of malignant Hodgkin and Reed-Sternberg (H/RS) cells, the authors initiated a pilot study of rituximab. Rituximab is used to primarily deplete normal B cells from HD lesions. METHO...

journal_title：Cancer

authors： Younes A,Romaguera J,Hagemeister F,McLaughlin P,Rodriguez MA,Fiumara P,Goy A,Jeha S,Manning JT Jr,Jones D,Abruzzo LV,Medeiros LJ

更新日期：2003-07-15 00:00:00

abstract：:The prognostic significance of the pretreatment growth characteristics of marrow blasts was examined in 37 patients with acute nonlymphocytic leukemia (ANLL) treated with a similar therapeutic regimen. Initial mitotic index (MI) and in vitro 3H-thymidine labeling index (LI) were broadly distributed showing no correlat...

journal_title：Cancer

authors： Amadori S,Petti MC,De Francesco A,Chierichini A,Mastrovincenzo C,Testa MG,Mandelli F

更新日期：1978-03-01 00:00:00

abstract：BACKGROUND:Lobular neoplasia (LN), also known as lobular carcinoma in situ, is an incidental histologic finding in tissue removed at breast surgery. Patients with LN are known to be predisposed to develop invasive or intraductal carcinoma (CA). This study investigates factors that influence the cancer risk in LN patien...

journal_title：Cancer

authors： Bodian CA,Perzin KH,Lattes R

更新日期：1996-09-01 00:00:00

abstract：:The authors describe a new technique for the subcutaneous heterotopic transplantation of the ovary before pelvic irradiation to treat Hodgkin's disease. Creation of a cavity to receive the transplant and the use of two surgical teams and the surgical microscope during the operation ensured its successful outcome. The ...

journal_title：Cancer

authors： Leporrier M,von Theobald P,Roffe JL,Muller G

更新日期：1987-11-01 00:00:00

abstract：:The incidence of gastric cancer has declined markedly in Finland during the last 4 decades. To document the changes caused by that in the ratio of the intestinal type (IT) to the diffuse type (DT) of gastric carcinoma we compared the 367 cases diagnosed from southwestern Finland at the Department of Pathology, Turku U...

journal_title：Cancer

authors： Laurén PA,Nevalainen TJ

更新日期：1993-05-15 00:00:00

abstract：BACKGROUND:Total body irradiation (TBI) is commonly used with autologous bone marrow transplantation (BMT) for treatment of hematologic malignancies. Pulmonary complications of TBI can cause long-term morbidity and mortality. The authors have compared the pulmonary toxicity and efficacy of two different TBI fractionati...

journal_title：Cancer

authors： Gopal R,Ha CS,Tucker SL,Khouri IF,Giralt SA,Gajewski JL,Andersson BS,Cox JD,Champlin RE

更新日期：2001-10-01 00:00:00

abstract：BACKGROUND:Although protein expressions of glucocorticoid receptor (GR), estrogen receptors (ERα and ERβ), progesterone receptor A (PgR-A), and androgen receptor (AR) were shown to play roles in the growth and differentiation of normal thymus and thymic tumors, to the authors' knowledge their association with patient c...

journal_title：Cancer

authors： Mimae T,Tsuta K,Takahashi F,Yoshida A,Kondo T,Murakami Y,Okada M,Takeuchi M,Asamura H,Tsuda H

更新日期：2011-10-01 00:00:00

abstract：:Image cytometry for the classification of fine needle aspirate (FNA) biopsies was evaluated in samples from 39 women. Eighteen of them had benign lesions, seven had premalignant lesions, nine had carcinoma in situ, and five had carcinoma. The term, premalignant, here refers to lesions with an increased risk of develop...

journal_title：Cancer

authors： King EB,Chew KL,Duarte L,Hom JD,Mayall BH,Miller TR,Petrakis NL

更新日期：1988-07-01 00:00:00

abstract：:The therapeutic effect of prednimustine was studied in 35 patients with advanced breast cancer resistant to previous cytotoxic and/or endocrine therapy. Response (PR + CR) was obtained in 14 patients (40%) of a median duration of five months. Among the 14 responding patients, 10 were resistant to previous endocrine th...

journal_title：Cancer

authors： Mouridsen HT,Kristensen D,Nielsen JH,Dombernowsky P

更新日期：1980-07-15 00:00:00

abstract：:Carcinoembryonic antigen (CEA) was measured in extracts of cell suspensions from tumors of the colon, stomach, breast, lung and kidney. Cell suspensions were also obtained from normal tissue surrounding the primary tumors. The number of neoplastic cells in each cell suspension was determined by cytologic criteria. Hig...

journal_title：Cancer

authors： MacSween JM,Anderson GH

更新日期：1977-08-01 00:00:00

abstract：BACKGROUND:Sedentary behaviors are associated with poor health outcomes in the general population, but their clinical impact on adult survivors of childhood acute lymphoblastic leukemia (ALL) has not been characterized to date. In the current study, we described the prevalence of sedentary behaviors in survivors of ALL...

journal_title：Cancer

authors： Howell CR,Wilson CL,Ehrhardt MJ,Partin RE,Kaste SC,Lanctot JQ,Pui CH,Robison LL,Hudson MM,Ness KK

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:The aims of this study were to compare human epidermal growth factor receptor 2 (HER2) results between immunohistochemistry (IHC) and fluorescence in situ hybridization (FISH), and to investigate the clinicopathological characteristics and outcomes according to their results. METHODS:Using consecutive tissu...

journal_title：Cancer

authors： Park S,Park HS,Koo JS,Yang WI,Kim SI,Park BW

更新日期：2012-02-15 00:00:00

abstract：:Cutaneous atypical fibroxanthoma (AFX) occurs in elderly persons as a small nodule or ulcernodule in actinically damaged skin of the head and neck area. The vast majority of AFX behave in a benign manner, and metastasis is rare. Eight examples of metastasizing AFX are reported. Factors that portend aggressive behavior...

journal_title：Cancer

authors： Helwig EB,May D

更新日期：1986-01-15 00:00:00

abstract：:Recent studies have indicated that the nuclear DNA content of certain malignant neoplasms can be used as an adjunct in predicting their biologic behavior. The DNA content of 99 ovarian carcinomas was determined by flow cytometric analysis of nuclei obtained from paraffin-embedded tissue. Of the 99 tumors, 51 were dipl...

journal_title：Cancer

authors： Brescia RJ,Barakat RA,Beller U,Frederickson G,Suhrland MJ,Dubin N,Demopoulos RI

更新日期：1990-01-01 00:00:00

abstract：:Dual tracer scintigraphy (DTS) (technetium 99m [99mTc] sulfur colloid and gallium 67 citrate [67 gallium citrate]) of the liver and computer subtraction studies (SS) were performed in 26 patients subsequently proven to have hepatocellular carcinoma (HCC) and 32 patients with cirrhosis and focal defects on the colloid ...

journal_title：Cancer

authors： Sostre S,Villagra D,Morales NE,Rivera JV

更新日期：1988-02-15 00:00:00

abstract：:Lymphocyte cyclic nucleotide content was studied before and after Levamisole administration to cancer patients. Twelve patients with disseminated cancer received 100 mg/m2 on two consecutive days; nine comparable patients with disseminated cancer served as controls. Endogenous cyclic adenosine monophosphate (cAMP) and...

journal_title：Cancer

authors： Lewinski UH,Mavligit GM,Thompson WJ,Hersh EM,Ortez RA

更新日期：1979-10-01 00:00:00

abstract：BACKGROUND:In the current study, the authors focused on determinants influencing the quality of care and variations in the actual quality of integrated care for patients with nonsmall cell lung cancer (NSCLC) to estimate whether there is room for improvement. METHODS:The authors tested the quality of integrated care f...

journal_title：Cancer

authors： Ouwens MM,Hermens RR,Termeer RA,Vonk-Okhuijsen SY,Tjan-Heijnen VC,Verhagen AF,Hulscher MM,Marres HA,Wollersheim HC,Grol RP

更新日期：2007-10-15 00:00:00

abstract：:Doxorubicin has been reported to cause ventricular arrhythmias and sudden death in the first 24 hours after administration. The authors placed continuous electrocardiographic recording devices on 30 patients 24 hours before, during, and 24 hours after doxorubicin administration. Nine patients experienced arrhythmias b...

journal_title：Cancer

authors： Friess GG,Boyd JF,Geer MR,Garcia JC

更新日期：1985-12-15 00:00:00

abstract：:Oncologic therapy demands technologic sophistication to meet the clinical challenges of proper drug administration for chemotherapeutic agents, pain management, antibiotics, hydration, antiemetic drugs, and total parenteral nutrition. Drug administration systems for patient-controlled analgesia include benefits of imp...

journal_title：Cancer

authors： Shaw HL

更新日期：1992-08-15 00:00:00

abstract：:The authors report the case of a child with retroperitoneal ganglioneuroma and cytodifferentiated skeletal metastases. The primary tumor was surgically resected, and the child is alive and well 2 years later without additional therapy. This rarely documented phenomenon can be explained by spontaneous cytomaturation wi...

journal_title：Cancer

authors： Garvin JH Jr,Lack EE,Berenberg W,Frantz CN

更新日期：1984-07-15 00:00:00

abstract：BACKGROUND:Breast conservation surgery (BCS) and mastectomy have equivalent survival outcomes for women with breast carcinoma, but treatment decisions are affected by many factors. The current study evaluated the impact of patient and physician factors on surgical decision-making. METHODS:Statistical analyses were per...

journal_title：Cancer

authors： Chagpar AB,Studts JL,Scoggins CR,Martin RC 2nd,Carlson DJ,Laidley AL,El-Eid SE,McGlothin TQ,Noyes RD,McMasters KM

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Patients with multiple myeloma (MM) have increased bone marrow angiogenesis, a low plasma cell labeling index, and multidrug resistance (the primary cause of chemotherapy failure). MM patients receiving the vincristine, doxorubicin, and dexamethasone (VAD) regimen develop resistance and cardiac and steroid t...

journal_title：Cancer

authors： Hussein MA,Wood L,Hsi E,Srkalovic G,Karam M,Elson P,Bukowski RM

更新日期：2002-11-15 00:00:00

abstract：:The metabolism of 5-fluorouracil (5-FU) was studied in biopsy specimens of primary colorectal cancer and healthy colonic mucosa obtained from previously untreated patients immediately after surgical removal. The conversion of 5-FU to anabolites was measured under saturating substrate (5-FU) and cosubstrate concentrati...

journal_title：Cancer

authors： Peters GJ,van Groeningen CJ,Laurensse EJ,Pinedo HM

更新日期：1991-11-01 00:00:00

abstract：:Seven children with advanced nasopharyngeal carcinoma younger than 20 years of age diagnosed between 1975 and 1986 (inclusive) were treated with a uniform adjuvant chemotherapy regimen, which consisted of vincristine (1.5 mg/m2; day 1), doxorubicin (45 mg/m2; day 1), 5-fluorouracil (8 mg/kg; days 1 through 5), and cyc...

journal_title：Cancer

authors： Kim TH,McLaren J,Alvarado CS,Wyly JB,Crocker I,Winn K,Singhapakdi S,Ragab A

更新日期：1989-05-15 00:00:00

abstract：BACKGROUND:It is well established that prenatal biologic processes are important for the development of some childhood cancers, whereas less is known regarding their influence on adult cancer risk. High birth weight has been associated with risk of breast cancer, whereas studies of other specific cancers and all cancer...

journal_title：Cancer

authors： Ahlgren M,Wohlfahrt J,Olsen LW,Sørensen TI,Melbye M

更新日期：2007-07-15 00:00:00

abstract：:Clinicopathologic correlations were made in 50 patients with follicular large cell (FLC) lymphoma to better define the influence of a variety of clinical and pathologic features on survival and the potential for continuous freedom from disease. The 5- and 10-year actuarial survivals for the entire group of patients ar...

journal_title：Cancer

authors： Horning SJ,Weiss LM,Nevitt JB,Warnke RA

更新日期：1987-04-15 00:00:00

abstract：BACKGROUND:The current study examines 1) the sensitivity of detection and 2) sampling and screening/diagnostic error in the cytologic diagnosis of adenocarcinoma in situ (AIS) of the cervix. The data were taken from public and private sector screening laboratories reporting 25,000 and 80,000 smears, respectively, each ...

journal_title：Cancer

authors： Schoolland M,Segal A,Allpress S,Miranda A,Frost FA,Sterrett GF

更新日期：2002-12-25 00:00:00

abstract：BACKGROUND:The purpose of this study was to identify biologic differences between ovarian clear cell carcinoma and other ovarian adenocarcinomas by comparing the expression of cell cycle regulatory molecules and by analyzing the survival of the patients. METHODS:In 51 cases of epithelial ovarian carcinoma, the express...

journal_title：Cancer

authors： Shimizu M,Nikaido T,Toki T,Shiozawa T,Fujii S

更新日期：1999-02-01 00:00:00

abstract：BACKGROUND:Metastatic adenocarcinoma in the liver with an unidentified primary tumor site is a common clinical problem. Pathologists often are asked to identify the primary tumor site. The histologic picture itself usually is not helpful, because the histology may be similar in the metastases of tumors with different p...

journal_title：Cancer

authors： Tot T

更新日期：1999-01-01 00:00:00

abstract：BACKGROUND:The aim of the current study was to assess circulating levels of endogenous endostatin in patients with renal carcinoma and to determine the relationship of these levels to circulating levels of vascular endothelial growth factor (VEGF) and prognosis. METHODS:The authors prospectively studied 66 patients (4...

journal_title：Cancer

authors： Feldman AL,Alexander HR Jr,Yang JC,Linehan WM,Eyler RA,Miller MS,Steinberg SM,Libutti SK

更新日期：2002-10-15 00:00:00