The quantitative relationship of carcinoembryonic antigen to tumor cells of different organs.

abstract：BACKGROUND:In view of the many studies of early stage colorectal carcinoma from Japan, it is essential to know whether the criteria for the histologic diagnosis of colorectal carcinoma are similar in Japan and Western countries. METHODS:Eight expert pathologists from Japan (4), North America (2), and Europe (2) indivi...

journal_title：Cancer

authors： Schlemper RJ,Itabashi M,Kato Y,Lewin KJ,Riddell RH,Shimoda T,Sipponen P,Stolte M,Watanabe H

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The effect of adjuvant chemotherapy after resection of nonsmall cell lung cancer (NSCLC) remains an unresolved question. METHODS:From October, 1982, to November, 1986, 267 patients with resected NSCLC were included in a randomized trial. The adjuvant allocated treatments were either postoperative radiothera...

journal_title：Cancer

authors： Dautzenberg B,Chastang C,Arriagada R,Le Chevalier T,Belpomme D,Hurdebourcq M,Lebeau B,Fabre C,Charvolin P,Guérin RA

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:Racial disparity in the incidence of multiple myeloma is well established; however, to the authors' knowledge, little is known regarding the impact of racial differences on disease characteristics, response to therapy, and clinical outcome. METHODS:The authors studied 453 patients (174 of whom were black an...

journal_title：Cancer

authors： Bhatnagar V,Wu Y,Goloubeva OG,Ruehle KT,Milliron TE,Harris CG,Rapoport AP,Yanovich S,Sausville EA,Baer MR,Badros AZ

更新日期：2015-04-01 00:00:00

abstract：:Fifty-nine colorectal carcinomas of patients with verified cancer family syndrome (CFS) were analyzed for DNA ploidy using flow cytometry. Sixty-eight percent of the tumors were diploid, and 32% were aneuploid. The aneuploid tumors had a median DNA index of 1.24 (range, 1.12-1.97). In 90% of all tumors the DNA index w...

journal_title：Cancer

authors： Kouri M,Laasonen A,Mecklin JP,Järvinen H,Franssila K,Pyrhönen S

更新日期：1990-04-15 00:00:00

abstract：:A clinicopathologic study of 51 patients with endoscopically removed large bowel polyps showing histologic evidence of malignancy, either focally, to a massive extent, or comprising the entire polyp, revealed only one absolute finding capable of predicting residual disease, namely, the presence of cancer at the resect...

journal_title：Cancer

authors： Lipper S,Kahn LB,Ackerman LV

更新日期：1983-11-01 00:00:00

abstract：:Almost all patients with prostatic cancer will eventually escape the control of the first-line endocrine therapy and relapse. This escape is attributed to selecting and/or cloning preexisting or de novo appearing hormone-independent or resistant cell lines and occurs in most patients after a median time of 12 to 18 mo...

journal_title：Cancer

authors： Mahler C,Denis L

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The current study was performed to describe frequencies and risk factors of altered oral health and odontogenesis in childhood cancer survivors. METHODS:In total, 9308 survivors who were diagnosed between 1970 and 1986 and 2951 siblings from the Childhood Cancer Survivor Study completed a survey that contai...

journal_title：Cancer

authors： Kaste SC,Goodman P,Leisenring W,Stovall M,Hayashi RJ,Yeazel M,Beiraghi S,Hudson MM,Sklar CA,Robison LL,Baker KS

更新日期：2009-12-15 00:00:00

abstract：:Serum trace elements (STE) were measured in 50 patients with chronic lymphocytic leukemia (CLL) and 100 normal subjects. Copper was higher in patients than in controls (1.50 +/- 0.06 versus 1.10 +/- 0.02 micrograms/ml, P less than 0.001), increased steadily from Stage 0 to Stage 4 (P = 0.002), and correlated with the ...

journal_title：Cancer

authors： Beguin Y,Brasseur F,Weber G,Bury J,Delbrouck JM,Roelandts I,Robaye G,Fillet G

更新日期：1987-10-15 00:00:00

abstract：BACKGROUND:Aggressive non-Hodgkin's lymphoma is now often curable with chemotherapy. The International Prognostic Index (IPI) was recently developed to predict patient survival on the basis of pretreatment clinical features. However, classical multivariate regression models such as the IPI fail to detect time-dependent...

journal_title：Cancer

authors： Mounier N,Morel P,Haioun C,Coiffier B,Tilly H,Chatelain C,Lederlin P,Thyss A,Herbrecht R,Gisselbrecht C,Lepage E

更新日期：1998-05-15 00:00:00

abstract：:Forty-five immunocompetent patients with solid tumors were immunized with BCG, PPD, and tumor cells. The methods were practical, but the morbidity was significant, including painful draining ulcerations at vaccine sites, possible enhancement of tumor growth in three patients, and the discovery at autopsy of systemic t...

journal_title：Cancer

authors： Gerner RE,Moore GE

更新日期：1976-07-01 00:00:00

abstract：:Ultrasonographic examinations and measurements of CA 19-9 and elastase 1 were done simultaneously in 14 patients with resectable pancreatic cancer of less than 3.0 cm in longest diameter and 48 patients with pancreatitis. Although a pancreatic mass was detected ultrasonically in only six (42.9%) of the patients with t...

journal_title：Cancer

authors： Iishi H,Yamamura H,Tatsuta M,Okuda S,Kitamura T

更新日期：1986-05-15 00:00:00

abstract：:The nuclear DNA content of 98 operable breast cancers was determined by flow cytometric analysis using paraffin-embedded tissue. All patients were on follow-up and failure of treatment or recurrences were identified. DNA ploidy data in the form of ploidy status and DNA index (DI) has been correlated with various clini...

journal_title：Cancer

authors： Sharma S,Mishra MC,Kapur BM,Verma K,Nath I

更新日期：1991-12-15 00:00:00

abstract：BACKGROUND:Multiple intraesophageal primary cancer and upper aerodigestive tract (UADT) cancer associated with esophageal cancer are common diseases, especially in heavy drinkers. They are often explained by the concept of field cancerization, which suggests a similar etiology. However, little is known about the nature...

journal_title：Cancer

authors： Yokoyama A,Muramatsu T,Ohmori T,Makuuchi H,Higuchi S,Matsushita S,Yoshino K,Maruyama K,Nakano M,Ishii H

更新日期：1996-05-15 00:00:00

abstract：BACKGROUND:This study was conducted to evaluate whether estramustine (estrogen mustard [EM]) is a promising alternative in the treatment of patients with epithelial ovarian carcinoma (OVCA). EM is a microtubule-associated protein (MAP) specific antimicrotubule agent with low toxicity. METHODS:The authors investigated ...

journal_title：Cancer

authors： Chen Z,Fadiel A,Jia JF,Sakamoto H,Carbone R,Naftolin F

更新日期：1999-06-15 00:00:00

abstract：BACKGROUND:Several investigators have reported the ability to establish xenografts in nude mice from children with neuroblastomas, but a correlation of prognosis with this establishment and the growth patterns of the neuroblastomas has not been reported. METHODS:Tumor specimens from 58 children with neuroblastomas wer...

journal_title：Cancer

authors： George BA,Yanik G,Wells RJ,Martin LW,Soukup S,Ballard ET,Gartside PS,Lampkin BC

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Single-walled carbon nanotubes (SWNTs) have remarkable physicochemical properties that may have several medical applications. The authors have discovered a novel property of SWNTs-heat release in a radiofrequency (RF) field-that they hypothesized may be used to produce thermal cytotoxicity in malignant cells...

journal_title：Cancer

authors： Gannon CJ,Cherukuri P,Yakobson BI,Cognet L,Kanzius JS,Kittrell C,Weisman RB,Pasquali M,Schmidt HK,Smalley RE,Curley SA

更新日期：2007-12-15 00:00:00

abstract：BACKGROUND:Extragonadal germ cell tumors (EGCT) are rare. They are biologically distinct from their testicular counterparts. Information regarding these tumors from the Far East is limited. More investigations are warranted to define the optimal treatment. METHODS:Retrospective review of the medical records of 59 pati...

journal_title：Cancer

authors： Hsu YJ,Pai L,Chen YC,Ho CL,Kao WY,Chao TY

更新日期：2002-08-15 00:00:00

abstract：BACKGROUND:Patients with advanced cancer often experience frequent and prolonged hospitalizations; however, the factors associated with greater health care utilization have not been described. We sought to investigate the relation between patients' physical and psychological symptom burden and health care utilization. ...

journal_title：Cancer

authors： Nipp RD,El-Jawahri A,Moran SM,D'Arpino SM,Johnson PC,Lage DE,Wong RL,Pirl WF,Traeger L,Lennes IT,Cashavelly BJ,Jackson VA,Greer JA,Ryan DP,Hochberg EP,Temel JS

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Differentiating primary glandular from high-grade squamous intraepithelial lesions (HSIL) that involve endocervical glands is not an uncommon diagnostic problem in liquid-based gynecological cytology. Squamous and atypical glandular cell lesions may show similar cytomorphologic features. The aim of this stud...

journal_title：Cancer

authors： Garcia MT,Acar BC,Jorda M,Gomez-Fernandez C,Ganjei-Azar P

更新日期：2007-02-25 00:00:00

abstract：BACKGROUND:The mortality rate associated with fever accompanied by pulmonary infiltrates after chemotherapy for hematologic malignancies remains higher than the corresponding rate associated with febrile neutropenia without pulmonary infiltrates. Nonetheless, few studies have focused on the factors that predict outcome...

journal_title：Cancer

authors： Offidani M,Corvatta L,Malerba L,Marconi M,Bichisecchi E,Cecchini S,Manso E,Principi T,Gasparini S,Leoni P

更新日期：2004-08-01 00:00:00

abstract：:There were no significant differences between the mean blood plasma (leukocyte-free) RNAase activity among 128 healthy women volunteers age 13-70 and 49 women with benign gynecological tumors. Exceptions to this finding were three apparently healthy women volunteers who had plasma enzyme activity which was higher than...

journal_title：Cancer

authors： Sheid B,Lu T,Pedrinan L,Nelson JH Jr

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:To explore the potential role of infiltrating benign B cells in classic Hodgkin disease (HD) lesions in supporting the survival of malignant Hodgkin and Reed-Sternberg (H/RS) cells, the authors initiated a pilot study of rituximab. Rituximab is used to primarily deplete normal B cells from HD lesions. METHO...

journal_title：Cancer

authors： Younes A,Romaguera J,Hagemeister F,McLaughlin P,Rodriguez MA,Fiumara P,Goy A,Jeha S,Manning JT Jr,Jones D,Abruzzo LV,Medeiros LJ

更新日期：2003-07-15 00:00:00

abstract：:Diagnostic advances currently have exceeded therapeutic gain. The present, however, is a transition phase. Chemotherapy, for example, has become curative for some tumors in recent years, rather than merely palliative, due to the precision permitted by advances in molecular biology. At this time, acceleration in the ba...

journal_title：Cancer

authors： Gusberg SB

更新日期：1987-10-15 00:00:00

abstract：:In order to determine whether the use of a sequence of chemotherapeutic regimens plus BCG could produce longer durations of remission in adult acute nonlymphocytic leukemia than maintenance therapy with cytosine arabinoside, 6-thioguanine, plus BCG, a randomized study was performed at Washington University. Upon achie...

journal_title：Cancer

authors： Presant CA,Berger NA,Klahr C,Phillips GL

更新日期：1980-07-01 00:00:00

abstract：BACKGROUND:Although protein expressions of glucocorticoid receptor (GR), estrogen receptors (ERα and ERβ), progesterone receptor A (PgR-A), and androgen receptor (AR) were shown to play roles in the growth and differentiation of normal thymus and thymic tumors, to the authors' knowledge their association with patient c...

journal_title：Cancer

authors： Mimae T,Tsuta K,Takahashi F,Yoshida A,Kondo T,Murakami Y,Okada M,Takeuchi M,Asamura H,Tsuda H

更新日期：2011-10-01 00:00:00

abstract：:Risk factors associated with local recurrences were analyzed from a series of 3445 clinical Stage I melanoma patients. In single-factor analysis, tumor thickness, ulceration, and increasing age were highly significantly predictive of recurrence (p less than 0.00001). After 5 years of follow-up, local recurrence rates ...

journal_title：Cancer

authors： Urist MM,Balch CM,Soong S,Shaw HM,Milton GW,Maddox WA

更新日期：1985-03-15 00:00:00

abstract：:The development of monoclonal antibodies has led to renewed interest in the use of antibodies to treat malignant disease. Unfortunately, treatment with unmodified antibodies has been disappointing. Therapy with unmodified antibodies has been limited by the failure of host effector mechanisms to eliminate antibody-coat...

journal_title：Cancer

authors： Badger CC,Bernstein ID

更新日期：1986-07-15 00:00:00

abstract：BACKGROUND:The authors suggested that the loss of collagen IV and laminin-containing basement membrane and the loss of Disabled-2 (Dab2) expression were two critical events associated with morphologic dysplastic changes of the ovarian surface epithelium as a step in tumorigenicity. Both the basement membrane and Dab2, ...

journal_title：Cancer

authors： Roland IH,Yang WL,Yang DH,Daly MB,Ozols RF,Hamilton TC,Lynch HT,Godwin AK,Xu XX

更新日期：2003-12-15 00:00:00

abstract：BACKGROUND:Breast cancers that are negative for the estrogen receptor (ER), the progesterone receptor (PR), and the HER2 (human epidermal growth factor receptor 2) marker are more prevalent among African women, and the biologically aggressive nature of these triple-negative breast cancers (TNBCs) may be attributed to t...

journal_title：Cancer

authors： Schwartz T,Stark A,Pang J,Awuah B,Kleer CG,Quayson S,Kingman S,Aitpillah F,Abantanga F,Jiagge E,Oppong JK,Osei-Bonsu E,Martin I,Yan X,Toy K,Adjei E,Wicha M,Newman LA

更新日期：2013-02-01 00:00:00

abstract：:Extremely high concentrations of human chorionic gonadotropin in the cerebrospinal fluid were found in a 5-year-old boy presenting sexual precocity and leg pain. An intramedullary spinal cord tumor was revealed by myelogram and metrizamide computerized tomography, and a biopsy specimen taken at laminectomy. Histologic...

journal_title：Cancer

authors： Hisa S,Morinaga S,Kobayashi Y,Ojima M,Chikaoka H,Sasano N

更新日期：1985-06-15 00:00:00