Familial glioblastoma with hepatic focal nodular hyperplasia.

abstract：:The case of a 71-year-old woman who developed generalized weakness, lymphadenopathy, and a skin rash during methyldopa therapy is described. The prompt disappearance of symptoms following the discontinuation of the drug implicates it in the initial triggering of the abnormal lymphoid proliferation. Shortly thereafter,...

journal_title：Cancer

authors： Weisenburger DD

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND:Serum alpha-L-fucosidase activity is considered a marker of hepatocellular carcinoma. To the authors' knowledge, its clinical usefulness in the early detection of hepatocellular carcinoma in the follow-up of cirrhotic patients has not been reported previously. METHODS:The authors prospectively studied serum...

journal_title：Cancer

authors： Giardina MG,Matarazzo M,Morante R,Lucariello A,Varriale A,Guardasole V,De Marco G

更新日期：1998-12-15 00:00:00

abstract：:Since 1981, 20 patients with anaplastic giant cell carcinoma of the thyroid have been prospectively treated according to a combination regimen of chemotherapy and external beam radiation therapy. Two types of chemotherapy were used every 4 weeks, depending on the patient's age. For those younger than 65 years, a combi...

journal_title：Cancer

authors： Schlumberger M,Parmentier C,Delisle MJ,Couette JE,Droz JP,Sarrazin D

更新日期：1991-02-01 00:00:00

abstract：:A case of sinus histiocytosis with massive lymphadenopathy (SHML) in which cranial nerve function was impaired is described. Severe paraparesis due to an epidural block at the C2 and C5-T2 levels was also present. Treatment with cytotoxic agents resulted in a dramatic decrease in the size of the involved lymph nodes a...

journal_title：Cancer

authors： Haas RJ,Helmig MS,Prechtel K

更新日期：1978-07-01 00:00:00

abstract：:A leukocyte migration procedure was utilized to test cellular hypersensitivity of breast cancer patients' leukocytes to autologous and homologous breast cancer tissues and to murine milk containing murine mammary tumor virus (MuMTV). The in vitro responsiveness of the leukocytes and the antigenicity of breast cancer t...

journal_title：Cancer

authors： Black MM,Zachrau RE,Shore B,Moore DH,Leis HP Jr

更新日期：1975-01-01 00:00:00

abstract：:Granulocyte (PMN) directional locomotion (migration) in vitro and in vivo, resting nitroblue tetrazolium (NBT)-reduction and adherence to nylon wool of polymorphonuclear neutrophils (PMN) were assayed in 7 patients with Hodgkin's disease (HD) and in 11 patients with non-Hodgkin's lymphoma (NHL) prior to therapy. In mo...

journal_title：Cancer

authors： Von Fliedner V,Salvatori V,Higby DJ,Stutzman L,Park BH

更新日期：1980-02-01 00:00:00

abstract：:Angioendotheliomatosis is a rare intravascular neoplastic process which has been presumed to be of endothelial origin. A 62-year-old woman had manifestations of this disorder which were initially localized to the nasal region, followed by fatal systemic dissemination. Electron microscopic examination of the neoplastic...

journal_title：Cancer

authors： Wick MR,Banks PM,McDonald TJ

更新日期：1981-12-01 00:00:00

abstract：BACKGROUND:Currently, there is no gold standard for the treatment of patients with metastatic breast carcinoma who have experienced failure with anthracyclines and taxanes. A biologic rationale suggests that the mechanism of taxane resistance could be because of an excess of depolymerized tubulin that could enhance sen...

journal_title：Cancer

authors： Zelek L,Barthier S,Riofrio M,Fizazi K,Rixe O,Delord JP,Le Cesne A,Spielmann M

更新日期：2001-11-01 00:00:00

abstract：:Disulfiram (tetraethylthiuram disulfide, Antabuse) and sodium diethyldithiocarbamate, when added to the diet, inhibit 1,2-dimethylhydrazine (DMH)-induced neoplasia of the large bowel in female CF1 mice. Ethylene bis(dithiocarbamato)manganese (Maneb) and bis(ethylxanthogen), two pesticides with structural similarities ...

journal_title：Cancer

authors： Wattenberg LW,Lam LK,Fladmoe AV,Borchert P

更新日期：1977-11-01 00:00:00

abstract：:Because increased effects have been achieved when murine tumors are irradiated after a period of hypoxia and because of anecdotal clinical experiences of an improved result after irradiation of previously anemic patients in hyperbaric oxygen, the relationship between irradiation and increased survival was investigated...

journal_title：Cancer

authors： Sealy R,Jacobs P,Wood L,Levin W,Barry L,Boniaszczuk J,Blekkenhorst G

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) are KIT-positive mesenchymal tumors of the gastrointestinal tract that are driven by activated KIT-signalling or platelet-derived growth factor receptor-alpha (PDFGRA) signaling. These tumors most commonly occur in the stomach and small intestine and encompass a clinic...

journal_title：Cancer

authors： Miettinen M,Kraszewska E,Sobin LH,Lasota J

更新日期：2008-02-01 00:00:00

abstract：:New approaches are needed in the treatment of advanced breast cancer. In vitro studies have shown that recombinant tumor necrosis factor (TNF) is a growth inhibitor for the MCF-7, ZR-75-1, and BT-20 human breast cancer cell lines. Based on these considerations, the Southwest Oncology Group performed a Phase II trial o...

journal_title：Cancer

authors： Budd GT,Green S,Baker LH,Hersh EP,Weick JK,Osborne CK

更新日期：1991-10-15 00:00:00

abstract：BACKGROUND:Cancer and its treatment lead to increased financial distress for patients. To the authors' knowledge, to date, no standardized patient-reported outcome measure has been validated to assess this distress. METHODS:Patients with AJCC Stage IV solid tumors receiving chemotherapy for at least 2 months were recr...

journal_title：Cancer

authors： de Souza JA,Yap BJ,Wroblewski K,Blinder V,Araújo FS,Hlubocky FJ,Nicholas LH,O'Connor JM,Brockstein B,Ratain MJ,Daugherty CK,Cella D

更新日期：2017-02-01 00:00:00

abstract：:Patients with ER positive primary tumors usually have initial metastases at the more favorable sites. Twelve out of 14 patients with ER positive had first site of metastases in either bone or soft tissue. In contrast, 13 of 17 patients with negative ER developed first metastases in viscera. ER positive patients respon...

journal_title：Cancer

authors： Singhakowinta A,Saunders DE,Brooks SC,Samal B,Vaitkevicius VK

更新日期：1980-12-15 00:00:00

abstract：BACKGROUND:The improved efficacy of imipenem over other beta-lactam antibiotics in the treatment of febrile neutropenic patients has been attributed to its broad spectrum of activity. METHODS:A prospective, randomized, clinical trial was performed comparing vancomycin 1 g every 12 hours plus imipenem/cilassatin 500 mg...

journal_title：Cancer

authors： Raad II,Whimbey EE,Rolston KV,Abi-Said D,Hachem RY,Pandya RG,Ghaddar HM,Karl CL,Bodey GP

更新日期：1996-04-01 00:00:00

abstract：:Two-hundred-four patients with previously untreated adenocarcinoma of rectum, rectosigmoid, and sigmoid colon were retrospectively evaluated to determine patterns of recurrence following curative resection. Seventy-eight (38%) subsequently developed recurrent disease. Of these, 40% (31/78) presented with local recurre...

journal_title：Cancer

authors： Rao AR,Kagan AR,Chan PM,Gilbert HA,Nussbaum H,Hintz BL

更新日期：1981-09-15 00:00:00

abstract：BACKGROUND:Nearly 50% of urothelial carcinoma patients with lymph node-negative invasive cancers recur after radical surgery. In many cases, occult local or lymph node disease may be present but undetectable by current approaches. Reverse-transcriptase polymerase chain reaction (RT-PCR)-detectable mRNA of Uroplakin II ...

journal_title：Cancer

authors： Copp HL,Chin JL,Conaway M,Theodorescu D

更新日期：2006-07-01 00:00:00

abstract：:A case of primary leptomeningeal B-cell lymphoma in an 8-year-old, previously healthy child is described. The child was found to have hypogammaglobulinemia, and the Epstein-Barr virus genome was identified in cultured tumor cells despite blood serology being negative for the virus. The patient was treated with cycloph...

journal_title：Cancer

authors： Hayani A,Venger BH,Rouah E,Laurent JP,Mahoney DH,McClain KL

更新日期：1990-10-15 00:00:00

abstract：BACKGROUND:The purpose of this study was to compare outcomes in patients with anal canal squamous cell carcinoma (SCCA) who were treated with definitive chemoradiotherapy by either intensity-modulated radiation therapy (IMRT) or conventional radiotherapy (CRT). METHODS:Forty-six patients who received definitive chemor...

journal_title：Cancer

authors： Bazan JG,Hara W,Hsu A,Kunz PA,Ford J,Fisher GA,Welton ML,Shelton A,Kapp DS,Koong AC,Goodman KA,Chang DT

更新日期：2011-08-01 00:00:00

abstract：:Clofarabine is a new-generation nucleoside analog that has been synthesized to combine the most favorable pharmacokinetic properties of its congeners fludarabine and cladribine. In addition to inhibition of DNA polymerases and DNA synthesis, clofarabine acts as a strong inhibitor of ribonucleotide reductase (RnR), an ...

journal_title：Cancer

authors： Faderl S,Gandhi V,Keating MJ,Jeha S,Plunkett W,Kantarjian HM

更新日期：2005-05-15 00:00:00

abstract：BACKGROUND:Failure to obtain the requisite follow-up of patients with abnormal mammograms may delay cancer diagnosis and impact outcome. Up to 20% of women do not receive timely recommended follow-up. The current study tested the accuracy of the linkage of payer claims and clinical data to identify the appropriate trea...

journal_title：Cancer

authors： Eberl MM,Watroba N,Reinhardt M,Pomerantz J,Serghany J,Broffman G,Fox CH,Mahoney MC,Edge SB

更新日期：2007-08-01 00:00:00

abstract：:Immunoblastic sarcoma is a malignancy of transformed lymphocytes with a high association of occurrence in patients with immune disorders. The youngest previously reported case occurred in a 6-year-old child with immunoblastic lymphadenopathy. The authors report the finding of immunoblastic sarcoma of B-cells in a prev...

journal_title：Cancer

authors： Larson T,Katz DA,Mailliard JA

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:The carboplatin-based chemotherapeutic regimen M-CAVI (methotrexate, carboplatin, and vinblastine) is active against bladder carcinoma and can be administered to patients who are ineligible to receive cisplatin or doxorubicin. The authors designed a randomized study to evaluate whether M-CAVI offers a therap...

journal_title：Cancer

authors： Bellmunt J,Ribas A,Eres N,Albanell J,Almanza C,Bermejo B,Solé LA,Baselga J

更新日期：1997-11-15 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of the rapamycin (mTOR) signaling pathway represents a promising target for cancer therapy. The phosphorylation status of Akt and of mTOR's phosphorylation target eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) is often used to assess the activity of Akt and mTOR signaling...

journal_title：Cancer

authors： Akcakanat A,Sahin A,Shaye AN,Velasco MA,Meric-Bernstam F

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Although there have been several reports of cytologic features for salivary duct carcinoma (SDC), it still can be difficult to diagnose patients with these tumor accurately at the time of fine-needle aspiration (FNA). Review of the literature indicates that, immunohistochemically, SDC expresses androgen rece...

journal_title：Cancer

authors： Moriki T,Ueta S,Takahashi T,Mitani M,Ichien M

更新日期：2001-10-25 00:00:00

abstract：:Oat-cell carcinoma of the thymus gland is exceedingly rare as a primary lesion, and only a few cases have been reported. We report a case in which a neoplasm interpreted as an oat-cell carcinoma was intimately associated with and arose in transition from a carcinoid tumor of the thymus. Ultrastructural features of thi...

journal_title：Cancer

authors： Wick MR,Scheithauer BW

更新日期：1982-04-15 00:00:00

abstract：BACKGROUND:Most commercial fecal occult blood tests (FOBT) used for colorectal carcinoma screening of Western populations are guaiac-based, manually developed, subjective, and sensitive to dietary components. Preliminary studies demonstrated the unsuitability of these tests for screening a Chinese population. The goal ...

journal_title：Cancer

authors： Wong WM,Lam SK,Cheung KL,Tong TS,Rozen P,Young GP,Chu KW,Ho J,Law WL,Tung HM,Choi HK,Lee YM,Lai KC,Hu WH,Chan CK,Yuen MF,Wong BC

更新日期：2003-05-15 00:00:00

abstract：BACKGROUND:Controlled-release (CR) morphine tablets have become routine therapy in the management of cancer pain. Compared with immediate-release (IR) morphine, this formulation provides the benefit of dosing every 12 hours. METHODS:This study reviewed the 10 published, well controlled, repeated-dose, comparative stud...

journal_title：Cancer

authors： Warfield CA

更新日期：1998-06-15 00:00:00

abstract：:The clinical experience and technologic improvements of the past 40 years are briefly summarized in terms of their contributions to the present optimistic and aggressive approach to the treatment of malignant lymphoma. The reasoning behind the large-field moderately high-dose technique that has evolved is reviewed and...

journal_title：Cancer

authors： Nobler MP

更新日期：1968-10-01 00:00:00

abstract：:Cases of systemic lupus erythematosus, systemic sclerosis, periarteritis nodosa, and dermato- and polymyositis autopsied in Japan during a recent, 7-year period (1972-1978) were studied to assess the incidence of cancer as a complication. In comparison with the other three groups, cases of dermato- and polymyositis (D...

journal_title：Cancer

authors： Okayasu I,Mizutani H,Kurihara H,Yanagisawa F

更新日期：1984-11-01 00:00:00