Immunoblastic lymphadenopathy associated with methyldopa therapy: a case report.

Abstract:

:The case of a 71-year-old woman who developed generalized weakness, lymphadenopathy, and a skin rash during methyldopa therapy is described. The prompt disappearance of symptoms following the discontinuation of the drug implicates it in the initial triggering of the abnormal lymphoid proliferation. Shortly thereafter, florid immunoblastic lymphadenopathy developed, and the patient subsequently responded to corticosteroid therapy. The frequent occurrence of immunoblastic lymphadenopathy during or shortly after the administration of various therapeutic medications is emphasized. The nature of the disorder and its differential diagnosis are discussed.

journal_name

Cancer

journal_title

Cancer

authors

Weisenburger DD

doi

10.1002/1097-0142(197811)42:5<2322::aid-cncr282042

subject

Has Abstract

pub_date

1978-11-01 00:00:00

pages

2322-7

issue

5

eissn

0008-543X

issn

1097-0142

journal_volume

42

pub_type

杂志文章

相关文献

CANCER文献大全
  • Breast cancer in women of Japanese and Caucasian ancestry in Hawaii.

    abstract::A pathology review of breast cancers in Japanese and Caucasian women indicates more numerous in situ carcinomas in the Japanese. Carcinomas with uniform nuclei were also more numerous among Japanese. Japanese women showed more extensive lymphocytic infiltrates adjacent to their tumors than did Caucasian women, and als...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19850701)56:1<206::aid-cncr28205

    authors: Stemmermann GN,Catts A,Fukunaga FH,Horie A,Nomura AM

    更新日期:1985-07-01 00:00:00

  • Anastrozole alone or in combination with tamoxifen versus tamoxifen alone for adjuvant treatment of postmenopausal women with early-stage breast cancer: results of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial efficacy and safety update ana

    abstract:BACKGROUND:The first analysis of the ATAC (Arimidex, Tamoxifen Alone or in Combination) trial (median follow-up, 33 months) demonstrated that in adjuvant endocrine therapy for postmenopausal patients with early-stage breast cancer, anastrozole was superior to tamoxifen in terms of disease-free survival (DFS), time to r...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/cncr.11745

    authors: Baum M,Buzdar A,Cuzick J,Forbes J,Houghton J,Howell A,Sahmoud T,ATAC (Arimidex, Tamoxifen Alone or in Combination) Trialists' Group.

    更新日期:2003-11-01 00:00:00

  • A nonrandom association between gastrointestinal stromal tumors and myeloid leukemia.

    abstract:BACKGROUND:Gastrointestinal stromal tumors (GISTs) are KIT-positive mesenchymal tumors of the gastrointestinal tract that are driven by activated KIT-signalling or platelet-derived growth factor receptor-alpha (PDFGRA) signaling. These tumors most commonly occur in the stomach and small intestine and encompass a clinic...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.23216

    authors: Miettinen M,Kraszewska E,Sobin LH,Lasota J

    更新日期:2008-02-01 00:00:00

  • Pleuropulmonary blastoma. The so-called pulmonary blastoma of childhood.

    abstract::The authors studied 11 pediatric intrathoracic neoplasms that share clinicopathologic features and constitute a specific tumor in children. These neoplasms were intrapulmonary, mediastinal, or pleural-based masses. A common histologic feature was the presence of small, primitive cells with blastematous qualities separ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19881015)62:8<1516::aid-cncr2820

    authors: Manivel JC,Priest JR,Watterson J,Steiner M,Woods WG,Wick MR,Dehner LP

    更新日期:1988-10-15 00:00:00

  • Perceived discrimination, trust in physicians, and prolonged symptom duration before ovarian cancer diagnosis in the African American Cancer Epidemiology Study.

    abstract:BACKGROUND:Discrimination and trust are known barriers to accessing health care. Despite well-documented racial disparities in the ovarian cancer care continuum, the role of these barriers has not been examined. This study evaluated the association of everyday discrimination and trust in physicians with a prolonged int...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.32451

    authors: Mullins MA,Peres LC,Alberg AJ,Bandera EV,Barnholtz-Sloan JS,Bondy ML,Funkhouser E,Moorman PG,Peters ES,Terry PD,Schwartz AG,Lawson AB,Schildkraut JM,Cote ML

    更新日期:2019-12-15 00:00:00

  • Primary cardiac tumors: forty years' experience with 71 patients.

    abstract:BACKGROUND:Primary cardiac tumors are infrequent, and few cardiac surgeons have extensive experience in treating them. The majority of the tumors are benign. As noninvasive diagnostic imaging of cardiac masses continues to improve, the number of these tumors that are seen by clinicians will increase. More of the malign...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19970501)79:9<1809::aid-cn

    authors: Perchinsky MJ,Lichtenstein SV,Tyers GF

    更新日期:1997-05-01 00:00:00

  • Multifocal adenocarcinoma of the jejunum.

    abstract::We report on an 89-year-old female admitted with signs of intestinal obstruction in whom three independent adenocarcinomas of the proximal jejunum were found. Multiple foci of pyloric gland metaplasia, glandular hyperplasia and dysplasia, carcinoma-in-situ, and several varieties of adenocarcinoma were identified on mi...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(197909)44:3<1142::aid-cncr282044

    authors: Warner TF,Peralta J

    更新日期:1979-09-01 00:00:00

  • Nonbleeding adenomas: Evidence of systematic false-negative fecal immunochemical test results and their implications for screening effectiveness-A modeling study.

    abstract:BACKGROUND:If some adenomas do not bleed over several years, they will cause systematic false-negative fecal immunochemical test (FIT) results. The long-term effectiveness of FIT screening has been estimated without accounting for such systematic false-negativity. There are now data with which to evaluate this issue. ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.29952

    authors: van der Meulen MP,Lansdorp-Vogelaar I,van Heijningen EM,Kuipers EJ,van Ballegooijen M

    更新日期:2016-06-01 00:00:00

  • The efficacy of Internet-based cognitive behavioral therapy for severely fatigued survivors of breast cancer compared with care as usual: A randomized controlled trial.

    abstract:BACKGROUND:Severe fatigue is a common and distressing symptom affecting approximately one in four survivors of breast cancer. The current study examined the efficacy of Internet-based cognitive behavioral therapy (ICBT) for severe fatigue in survivors of breast cancer compared with care as usual (CAU). METHODS:The aut...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.30815

    authors: Abrahams HJG,Gielissen MFM,Donders RRT,Goedendorp MM,van der Wouw AJ,Verhagen CAHHVM,Knoop H

    更新日期:2017-10-01 00:00:00

  • Latent hepatitis B virus infection in childhood hepatocellular carcinoma. Analysis by polymerase chain reaction.

    abstract::The presence of hepatitis B virus (HBV) has been evaluated in liver specimens from 11 children with primary liver tumors and negative results of serologic testing for HBV markers. HBV-DNA sequences were detected by the polymerase chain reaction procedure, using different sets of oligonucleotide primers from highly con...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920601)69:11<2731::aid-cncr282

    authors: Pontisso P,Morsica G,Ruvoletto MG,Barzon M,Perilongo G,Basso G,Cecchetto G,Chemello L,Alberti A

    更新日期:1992-06-01 00:00:00

  • Cytologic factors associated with prognosis in patients with peripheral adenocarcinoma of the lung measuring 3 cm or less in greatest dimension.

    abstract:BACKGROUND:Recently, peripheral lung adenocarcinomas (PLA) measuring < or = 3 cm in greatest dimension often have been diagnosed using diagnostic radiology. The objective of the current study was to determine which cytologic factors are associated with a favorable outcome and an unfavorable outcome in patients with PLA...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20686

    authors: Kobayashi Y,Yokose T,Kawamura K,Iwasaki S,Murata Y,Onuma S,Hasebe T,Nagai K,Sasaki S,Ochiai A

    更新日期:2005-02-25 00:00:00

  • Guideline-concordant cancer care and survival among American Indian/Alaskan Native patients.

    abstract:BACKGROUND:American Indians/Alaskan Natives (AI/ANs) have the worst 5-year cancer survival of all racial/ethnic groups in the United States. Causes for this disparity are unknown. The authors of this report examined the receipt of cancer treatment among AI/AN patients compared with white patients. METHODS:This was a r...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.28683

    authors: Javid SH,Varghese TK,Morris AM,Porter MP,He H,Buchwald D,Flum DR,Collaborative to Improve Native Cancer Outcomes (CINCO).

    更新日期:2014-07-15 00:00:00

  • Immune complexes, serum proteins, cell-mediated immunity, and immune regulation in patients with squamous cell carcinoma of the head and neck.

    abstract::A collaborative study of the humoral and cellular immune status of patients with carcinoma of the Head and Neck (H&N) was conducted at the West Virginia University (WVU) hospital. In addition, blind-coded serum panels were supplied on H&N cancer patients being treated at the National Cancer Institute (NCI). Serum prot...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860615)57:12<2295::aid-cncr282

    authors: Veltri RW,Rodman SM,Maxim PE,Baseler MW,Sprinkle PM

    更新日期:1986-06-15 00:00:00

  • Influence of provider factors and race on uptake of breast cancer gene expression profiling.

    abstract:BACKGROUND:Gene expression profiling (GEP) has been rapidly adopted for early breast cancer and can aid in chemotherapy decision making. Study results regarding racial disparities in testing are conflicting, and may reflect different care settings. To the authors' knowledge, data regarding the influence of provider fac...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.31222

    authors: Reeder-Hayes KE,Wheeler SB,Baggett CD,Zhou X,Meng K,Roberts MC,Carey LA,Meyer AM

    更新日期:2018-04-15 00:00:00

  • MIB-1 labeling index in nonpilocytic astrocytoma of childhood: a study of 101 cases.

    abstract:BACKGROUND:The prognosis of pediatric patients with nonpilocytic astrocytoma, and in particular those with anaplastic astrocytoma, is somewhat unpredictable. This study used MIB-1 monoclonal antibody, a proliferative marker that can be used in formalin fixed paraffin embedded tissues, to study nonpilocytic pediatric as...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/(sici)1097-0142(19980615)82:12<2459::aid-c

    authors: Ho DM,Wong TT,Hsu CY,Ting LT,Chiang H

    更新日期:1998-06-15 00:00:00

  • Improving prognosis of glioblastoma in the 21st century: who has benefited most?

    abstract:BACKGROUND:Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults. Temozolomide was rapidly incorporated into first-line treatment following the publication of the pivotal European Organization for Research and Treatment of Cancer-National Cancer Institute of Canada phase 3 trial in 2005. Howe...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26685

    authors: Lawrence YR,Mishra MV,Werner-Wasik M,Andrews DW,Showalter TN,Glass J,Shen X,Symon Z,Dicker AP

    更新日期:2012-09-01 00:00:00

  • Early lung cancer action project: overall design and findings from baseline screening.

    abstract:BACKGROUND:The Early Lung Cancer Action Project (ELCAP) is designed to evaluate baseline and annual repeat screening by low radiation dose computed tomography (low-dose CT) in persons at high-risk for lung cancer. The authors report on the baseline screening experience. For full evaluation of screening, they await the ...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(20001201)89:11+<2474::aid-cncr26

    authors: Henschke CI

    更新日期:2000-12-01 00:00:00

  • Suppression of proline-directed protein kinase F(A) expression potentiates erythroid differentiation of human myeloid leukemia cells.

    abstract:BACKGROUND:Initial clinic studies revealed that the overexpression of proline-directed protein kinase F(A) (PDPK F(A)) is associated conversely with various stages of tumor tissue differentiation. However, the role of overexpressed PDPK F(A) in tumor cell differentiation remains unknown and needs to be established. In ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Hsu CP,Yang CC,Yang SD

    更新日期:2000-09-01 00:00:00

  • Colorectal cancer stage at diagnosis by socioeconomic and urban/rural status in California, 1988-2000.

    abstract:BACKGROUND:Rural residence has been associated with increased risk of late stage cancer diagnosis, but it is unknown if this is related to lower socioeconomic status (SES) of rural residents or to other factors. This study examined the impacts of SES and urban/rural status on colorectal cancer (CRC) stage at diagnosis ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22016

    authors: Parikh-Patel A,Bates JH,Campleman S

    更新日期:2006-09-01 00:00:00

  • Mediterranean Kaposi's sarcoma in the elderly. A randomized study of oral etoposide versus vinblastine.

    abstract:BACKGROUND:This Phase III trial was performed to compare the roles of oral etoposide and intravenous (i.v.) vinblastine in the treatment of Mediterranean Kaposi's Sarcoma (MEKS) in elderly patients with severe disease (Stages II, Ac/B, III, and IV). PATIENTS AND METHODS:Sixty-five patients were randomized to receive e...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/1097-0142(19941115)74:10<2873::aid-cncr282

    authors: Brambilla L,Labianca R,Boneschi V,Fossati S,Dallavalle G,Finzi AF,Luporini G

    更新日期:1994-11-15 00:00:00

  • Protein kinase C activity in human colonic adenoma and colorectal carcinoma.

    abstract::To additionally understand the molecular mechanisms and biologic indicators of colonic tumorigenesis through the adenoma-carcinoma sequence, protein kinase C (PKC) activity was examined in the cytosol and particulate fraction of specimen homogenates from 18 human colonic carcinomas and seven coexisting colonic adenoma...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19920101)69:1<24::aid-cncr282069

    authors: Kusunoki M,Sakanoue Y,Hatada T,Yanagi H,Yamamura T,Utsunomiya J

    更新日期:1992-01-01 00:00:00

  • Long-term adjustment of survivors of early-stage breast carcinoma, 20 years after adjuvant chemotherapy.

    abstract:BACKGROUND:The long-term impact of breast carcinoma and its treatment was assessed in 153 breast carcinoma survivors previously treated on a Phase III randomized trial (Cancer and Leukemia Group B [CALGB 7581]) a median of 20 years after entry to CALGB 7581. METHODS:Survivors were interviewed by telephone using the fo...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1002/cncr.11531

    authors: Kornblith AB,Herndon JE 2nd,Weiss RB,Zhang C,Zuckerman EL,Rosenberg S,Mertz M,Payne D,Jane Massie M,Holland JF,Wingate P,Norton L,Holland JC

    更新日期:2003-08-15 00:00:00

  • Prognostic and therapeutic impact of the chromosome 20q13.2 ZNF217 locus amplification in ovarian clear cell carcinoma.

    abstract:BACKGROUND:The goal of this study was to examine the clinical significance of ZNF217 amplification and assess whether ZNF217 could be a potential therapeutic target in ovarian clear cell carcinoma (OCCC). METHODS:ZNF217 expression and amplification in OCCC was assessed by immunohistochemistry, fluorescence in situ hyb...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26598

    authors: Rahman MT,Nakayama K,Rahman M,Nakayama N,Ishikawa M,Katagiri A,Iida K,Nakayama S,Otsuki Y,Shih IeM,Miyazaki K

    更新日期:2012-06-01 00:00:00

  • The role of chemotherapy for node-negative breast cancer.

    abstract::Approximately 25% of women with early stage breast cancer and negative axillary nodes will eventually die of metastatic disease. Some studies have shown a recurrence rate of 40% or more at 10 years in this relatively good prognostic group. The incidence of breast cancer continues to increase approximately 1% per year ...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:

    authors: Cooper MR

    更新日期:1991-03-15 00:00:00

  • Malignant mucosal melanoma of the head and neck: review of the literature and report of 14 patients.

    abstract:BACKGROUND:Fortunately, primary malignant mucosal melanoma of the head and neck is a rare entity. A paucity of data elucidating the predictive factors as well as the unpredictable and aggressive biologic behavior of mucosal melanoma compound the vexing clinical situation. This review summarizes what the literature reve...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/(sici)1097-0142(19971015)80:8<1373::aid-cn

    authors: Manolidis S,Donald PJ

    更新日期:1997-10-15 00:00:00

  • The epidemiology of cervical carcinogenesis.

    abstract::Epidemiologic and laboratory data suggest that cervical cancer typically arises from a series of causal steps. Each step can be studied separately in the hope of better etiologic understanding and improved cancer prevention. The earliest identified etiologic step is infection of young women with specific types of vene...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(19951115)76:10+<1888::aid-cncr28

    authors: Schiffman MH,Brinton LA

    更新日期:1995-11-15 00:00:00

  • Does local recurrence affect the rate of distant metastases and survival in patients with early-stage breast carcinoma treated with breast-conserving therapy?

    abstract:BACKGROUND:The purpose of the current analysis was to evaluate the impact of local recurrence (LR) on the development of distant metastases (DM), overall survival (OS), and cause specific survival (CSS) in patients with early-stage breast carcinoma who underwent conservative surgery (CS) and received postoperative radi...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.11143

    authors: Vicini FA,Kestin L,Huang R,Martinez A

    更新日期:2003-02-15 00:00:00

  • Molecular mechanisms of osteolytic bone metastases.

    abstract:BACKGROUND:Breast carcinoma commonly metastasizes to the skeleton in patients with advanced disease to cause bone destruction and the associated pain, hypercalcemia, fracture, and nerve-compression syndromes. In this scenario, the bone destruction is mediated by the osteoclast. Tumor-produced parathyroid hormone-relate...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/1097-0142(20000615)88:12+<2892::aid-cncr2>

    authors: Guise TA

    更新日期:2000-06-15 00:00:00

  • Oncofertility and preservation of reproductive capacity in children and young adults.

    abstract::With increasing numbers of survivors from cancer at a young age, the issue of fertility preservation has assumed greater importance. This review describes normal ovarian and testicular function and summarizes what is known about the effect of chemotherapy and radiotherapy on the gonads and uterus. All young patients w...

    journal_title:Cancer

    pub_type: 杂志文章,评审

    doi:10.1002/cncr.26045

    authors: Wallace WH

    更新日期:2011-05-15 00:00:00

  • Epstein-Barr virus in gastric carcinoma with lymphoid stroma. Special reference to its detection by the polymerase chain reaction and in situ hybridization in 99 tumors, including a morphologic analysis.

    abstract:BACKGROUND:Gastric carcinoma with lymphoid stroma (GCLS) has been reported to have a more favorable prognosis than ordinary gastric carcinoma, however, the precise mechanism of the pathogenesis for GCLS remains unclear. METHODS:The authors analyzed 99 GCLS in 94 patients for Epstein-Barr virus (EBV) sequences using po...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19940501)73:9<2239::aid-cncr2820

    authors: Nakamura S,Ueki T,Yao T,Ueyama T,Tsuneyoshi M

    更新日期:1994-05-01 00:00:00