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Primary cardiac tumors: forty years' experience with 71 patients.

Abstract：

BACKGROUND:Primary cardiac tumors are infrequent, and few cardiac surgeons have extensive experience in treating them. The majority of the tumors are benign. As noninvasive diagnostic imaging of cardiac masses continues to improve, the number of these tumors that are seen by clinicians will increase. More of the malignant tumors may be curable if detected at an earlier stage. METHODS:A retrospective review was conducted of all patients with primary cardiac tumors managed by a university teaching center over a period of 40 years, using hospital medical records and a Provincial cardiovascular surgery database. RESULTS:Seventy-one patients (25 males and 46 females) with primary cardiac tumors were identified. Fifty-seven (80%) were benign masses and 14 (20%) were malignant masses. Twenty-eight percent of the tumors in men were malignant (7 of 25) compared with only 15% in women (7 of 46). Seventy-two percent of the masses were located in the left atrium. Forty-three percent of tumors in the right atrium were malignant (6 of 14) compared with only 14% in the left atrium (7 of 51). Complete resection was possible for 50 of 52 benign atrial tumors (96%) but for only 5 of 14 malignant tumors (36%). There was one perioperative death (1.4%). Three patients had no surgery because of their poor medical condition. Two of the patients with unresectable malignant tumors were still alive at last follow-up. The remaining 12 patients with malignancy have all died of their disease. CONCLUSIONS:Primary cardiac tumors are uncommon. Most patients present with symptoms of congestive heart failure. The second most common presenting symptom is embolization. Improvement in noninvasive diagnostic technology has increased the number of patients identified with a primary cardiac tumor and has also increased the number referred for surgical resection. The majority of left atrial tumors were benign, whereas up to one-half of tumors found in the right atrium were malignant. A greater proportion of malignant primary tumors were found in men than in women. Malignant cardiac tumors tend to be diagnosed after they have become extensive and the patients already have a very grave prognosis.

journal_name

Cancer

journal_title

Cancer

authors

Perchinsky MJ,Lichtenstein SV,Tyers GF

doi

10.1002/(sici)1097-0142(19970501)79:9<1809::aid-cn

subject

Has Abstract

pub_date

1997-05-01 00:00:00

pages

1809-15

issue

eissn

0008-543X

issn

1097-0142

pii

10.1002/(SICI)1097-0142(19970501)79:9<1809::AID-CN

journal_volume

pub_type

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Primary cardiac tumors: forty years' experience with 71 patients.