Malignant clear cell acrospiroma.

abstract：BACKGROUND:p53 plays a critical role in cellular anticancer mechanisms, and has been correlated with second primary malignancy (SPM) development. A common polymorphism in codon 72 of p53 results in an amino acid substitution and could influence p53 function. The authors hypothesized that p53 codon 72 polymorphism may b...

journal_title：Cancer

authors： Li F,Sturgis EM,Chen X,Zafereo ME,Wei Q,Li G

更新日期：2010-05-15 00:00:00

abstract：:A previous study evaluated two types of endometrial carcinoma: one with, the other without, associated adenomatous hyperplasia (Groups 1 and 2, respectively). On the basis of histologic observations, the study concluded that Group 1 tumors were likely to be estrogen-dependent, whereas Group 2 tumors appeared to repres...

journal_title：Cancer

authors： Deligdisch L,Holinka CF

更新日期：1986-04-01 00:00:00

abstract：BACKGROUND:This retrospective study evaluated the benefit of using tumor necrosis factor (TNF) and melphalan administered via an isolated limb perfusion (ILP) in a series of patients with metastatic melanoma who failed initial ILP with chemotherapeutics. METHODS:Seventeen patients with extremity melanoma who underwent...

journal_title：Cancer

authors： Bartlett DL,Ma G,Alexander HR,Libutti SK,Fraker DL

更新日期：1997-12-01 00:00:00

abstract：:Forty-six examples of carcinoma cuniculatum, a rare variant of squamous cell carcinoma of the skin, were studied by means of light and electron microscopy and immunoperoxidase techniques. The tumors usually presented as ulcerated, fungating, and polypoid masses with openings of sinus tracts onto the skin surface that ...

journal_title：Cancer

authors： Kao GF,Graham JH,Helwig EB

更新日期：1982-06-01 00:00:00

abstract：:Lobular carcinoma in situ (LCIS) has uncertain malignant potential; biologic markers that will identify patients at risk for a poor clinical outcome have been sought actively. Amplification of the c-erbB-2 protooncogene has been correlated with poor prognosis in invasive mammary carcinoma, and immunohistochemical eval...

journal_title：Cancer

authors： Porter PL,Garcia R,Moe R,Corwin DJ,Gown AM

更新日期：1991-07-15 00:00:00

abstract：:A spontaneous complete remission of 34 months' duration was observed in an adult patient with acute myeloblastic leukemia. The remission occurred after a severe febrile pneumonia, which was treated with leukocyte transfusions. At relapse, chromosomal abnormalities reappeared slowly. Such spontaneous complete remission...

journal_title：Cancer

authors： Ifrah N,James JM,Viguie F,Marie JP,Zittoun R

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Sixty cases of axillary metastases from clinically occult breast cancer were analyzed. All cases had histologic evidence of metastatic nodes compatible with breast carcinoma. METHODS:Thirty-three patients underwent breast surgery at the time of histologic diagnosis of the axillary metastases, 6 patients wer...

journal_title：Cancer

authors： Merson M,Andreola S,Galimberti V,Bufalino R,Marchini S,Veronesi U

更新日期：1992-07-15 00:00:00

abstract：:Two children with metastatic extragonadal endodermal sinus tumor who had failed VAC chemotherapy were treated with combination chemotherapy consisting of cis-platinum, vinblastine, doxorubicin HCl (Adriamycin) and bleomycin (cis-VAB). There was a complete response in both patients with one child remaining tumor-free 3...

journal_title：Cancer

authors： Thomas WJ,Kelleher JF,Duval-Arnould B

更新日期：1981-12-01 00:00:00

abstract：:The East Harlem Partnership for Cancer Awareness (EHPCA) was formed in 1999 to reduce disparities in cancer screening and prevention among medically underserved minorities residing in a large urban community (East Harlem, New York City) by increasing awareness of cancer risk, prevention, and treatment, and promoting g...

journal_title：Cancer

authors： Jandorf L,Fatone A,Borker PV,Levin M,Esmond WA,Brenner B,Butts G,Redd WH

更新日期：2006-10-15 00:00:00

abstract：:Treatment of 91 consecutive patients having metastatic, Stage IV melanoma who had not received any previous chemotherapy was begun between January 1977 and April 1978. The therapy included bleomycin (B) at 7.5 units subcutaneously in the first course and 15 units in subsequent courses on days 1 and 4; vincristine or O...

journal_title：Cancer

authors： Seigler HF,Lucas VS Jr,Pickett NJ,Huang AT

更新日期：1980-12-01 00:00:00

abstract：:A study of primary epithelial neoplasms of the appendix (with the exception of classical carcinoids), produced 24 adenocarcinomas and 42 benign lesions from the files of the Laboratory of Surgical Pathology of Columbia University. Invasive adenoarcinomas were often complicated by appendicitis and were then unexpectedl...

journal_title：Cancer

authors： Wolff M,Ahmed N

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND:With the move away from classical radical mastectomy to ever more skin-sparing procedures, there has been an ongoing discussion about how much skin and subcutaneous tissue should be resected to perform an adequate mastectomy while leaving viable skin flaps. One of the common recommendations is to dissect jus...

journal_title：Cancer

authors： Beer GM,Varga Z,Budi S,Seifert B,Meyer VE

更新日期：2002-03-15 00:00:00

abstract：BACKGROUND:Overall survival (OS) is considered the gold standard for determining treatment efficacy in oncology trials, but the relation between treatment and OS can be challenging to assess because of long study durations and the impact of subsequent therapies on outcome. Using OS can be particularly difficult for new...

journal_title：Cancer

authors： Smith BD,DeZern AE,Bastian AW,Durie BGM

更新日期：2017-05-15 00:00:00

abstract：:An all inclusive, widely accepted system for correlation of indices of pathophysiology in endometrial cancer with a spectrum of therapeutic management has yet to be developed. Improved understanding of tumor growth should lead to more logical, individualized treatment especially in terms of irradiation. To support the...

journal_title：Cancer

authors： Lewis GC Jr,Mortel R,Slack NH

更新日期：1977-02-01 00:00:00

abstract：BACKGROUND:Gastrointestinal stromal tumors (GISTs) historically were grouped with leiomyosarcomas (LMSs) based on their morphologic similarities; however, recently, GIST was established unequivocally as a distinct type of sarcoma based on its molecular features and response to imatinib treatment. METHODS:To gain furth...

journal_title：Cancer

authors： Ylipää A,Hunt KK,Yang J,Lazar AJ,Torres KE,Lev DC,Nykter M,Pollock RE,Trent J,Zhang W

更新日期：2011-01-15 00:00:00

abstract：:Giant sections from cystectomy specimens in 45 cases of bladder cancer were examined microscopically after en bloc fixation and processing. There were 35 transitional cell, seven squamous cell, and three mixed transitional cell and squamous carcinomas. Broad front invasion was associated with papillary and superficial...

journal_title：Cancer

authors： Soto EA,Friedell GH,Tiltman AJ

更新日期：1977-02-01 00:00:00

abstract：:Pancreatic carcinomas have been induced in Wistar and W/LEW rats by administration of total azaserine doses of 150-520 mg/kg by injection or oral routes over periods of 5-52 weeks. The latent period for development of invasive carcinomas was 1-2 years, but focal abnormalities in acinar cells appear earlier. The incide...

journal_title：Cancer

authors： Longnecker DS,Roebuck BD,Yager JD Jr,Lilja HS,Siegmund B

更新日期：1981-03-15 00:00:00

abstract：BACKGROUND:The current study was performed to compare the value of sentinel lymph node dissection (SND) and axillary lymph node dissection (AND) in improving the utility-adjusted survival for early-stage breast carcinoma patients. METHODS:A number needed to treat (NNT) analysis was used to compare SND with AND. In the...

journal_title：Cancer

authors： Jani AB,Basu A,Heimann R,Hellman S

更新日期：2003-01-15 00:00:00

abstract：BACKGROUND:Nilotinib is a potent, second-generation inhibitor of BCR-ABL1 tyrosine kinase and has been approved as frontline and salvage therapy for patients with chronic-phase chronic myeloid leukemia (CP-CML). METHODS:In this single-institution, phase 2 study, 122 patients with newly diagnosed CP-CML received niloti...

journal_title：Cancer

authors： Masarova L,Cortes JE,Patel KP,O'Brien S,Nogueras-Gonzalez GM,Konopleva M,Verstovsek S,Garcia-Manero G,Ferrajoli A,Kadia TM,Ravandi-Kashani F,Borthakur G,DellaSala S,Estrov Z,Jabbour EJ,Kantarjian HM

更新日期：2020-04-01 00:00:00

abstract：:Parathyroid adenomas are subdivided into chief cell and oxyphil cell variants. However, the parathyroid carcinomas described thus far have been only of the chief cell type. Two cases of oxyphil cell carcinoma of the parathyroid gland are reported, with light and electron microscopic study. The patients presented appar...

journal_title：Cancer

authors： Obara T,Fujimoto Y,Yamaguchi K,Takanashi R,Kino I,Sasaki Y

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Among the several proposed risk classification schemes for predicting survival in women with breast carcinoma, one of the most commonly used is the Nottingham Prognostic Index (NPI). The goal of the current study was to use a continuous prognostic model (similar to those that have already been demonstrated t...

journal_title：Cancer

authors： Kattan MW,Giri D,Panageas KS,Hummer A,Cranor M,Van Zee KJ,Hudis CA,Norton L,Borgen PI,Tan LK

更新日期：2004-12-01 00:00:00

abstract：:Forty-five immunocompetent patients with solid tumors were immunized with BCG, PPD, and tumor cells. The methods were practical, but the morbidity was significant, including painful draining ulcerations at vaccine sites, possible enhancement of tumor growth in three patients, and the discovery at autopsy of systemic t...

journal_title：Cancer

authors： Gerner RE,Moore GE

更新日期：1976-07-01 00:00:00

abstract：:The majority of patients with advanced ovarian cancer progress after first-line therapy and require further treatment. Tumor biology, prior chemotherapy, responses to previous therapy, performance status, and toxicity are the characteristics that influence treatment choice. These criteria have been linked to the time ...

journal_title：Cancer

authors： Pignata S,Pisano C,Di Napoli M,Cecere SC,Tambaro R,Attademo L

更新日期：2019-12-15 00:00:00

abstract：:Between January 1, 1980, and July 31, 1985, 168 patients were treated at our institution for chronic lymphocytic leukemia (CLL). Splenectomy was performed on 32 (23 men and 9 women). The mean age of these surgical patients was 59.4 years (range, 43-75). Twenty-four patients had received chemotherapy and/or corticother...

journal_title：Cancer

authors： Delpero JR,Gastaut JA,Letreut YP,Caamano A,Mathieu-Tubiana N,Maraninchi D,Simon-Lejeune C,Mascret B,Blanc AP,Sebahoun G

更新日期：1987-01-15 00:00:00

abstract：BACKGROUND:Despite published reports regarding the association of elevated circulating CD44 and CD54 levels with unfavorable outcome in non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL), little is known about therapy-related changes in either adhesion molecule. In an attempt to evaluate the effect of in...

journal_title：Cancer

authors： Beksaç M,Arat M,Akan H,Koç H,Ilhan O,Ozcan M

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:The aim of this work was to study the expression of alpha, beta1, and beta4 integrin subunits in meningiomas. METHODS:Seventeen atypical or anaplastic meningiomas were retrieved from the files of Hôpital de Bellevue, Saint-Etienne, France. They were compared with 17 benign meningiomas consecutively examined...

journal_title：Cancer

authors： Beschet I,Brunon J,Scoazec JY,Mosnier JF

更新日期：1999-12-15 00:00:00

abstract：BACKGROUND:Previously, the patient-reported Total Illness Burden Index for Prostate Cancer (TIBI-CaP) questionnaire and/or the physician-reported Charlson Comorbidity Index (CCI) have provided assessments of competing comorbidity during treatment decisions for patients with prostate cancer. In the current study, the au...

journal_title：Cancer

authors： Liss MA,Billimek J,Osann K,Cho J,Moskowitz R,Kaplan A,Szabo RJ,Kaplan SH,Greenfield S,Dash A

更新日期：2013-07-01 00:00:00

abstract：:Three children with nonlymphoblastic, non-Hodgkin's lymphomas, showed morphologic features that suggested nonlymphoblastic T-cell origin. Tissue for immunologic study was available from two of the three patients; both showed immunophenotypes of T-cells. Although nearly all T-cell lymphomas in children are lymphoblasti...

journal_title：Cancer

authors： Bitter MA,Nachman J,Jones N,Franklin WA,Le Beau MM,Vardiman JW

更新日期：1987-06-15 00:00:00

abstract：:In a retrospective analysis of 166 patients with chronic hepatitis B followed for up to 8 years, 22 patients had 29 episodes of elevations in serum alpha-fetoprotein (AFP) levels. Twenty-five episodes were due to a transient exacerbation of the underlying hepatitis and 11 of these episodes were followed by a loss of h...

journal_title：Cancer

authors： Di Bisceglie AM,Hoofnagle JH

更新日期：1989-11-15 00:00:00

abstract：:A patient is presented who developed a peritoneal malignant mesothelioma in association with severe persistent and recurrent diverticulitis. The case is unusual in that a spectrum of mesothelial proliferation was documented beginning initially as benign foci of mesothelial proliferation and passing through a stage of ...

journal_title：Cancer

authors： Riddell RH,Goodman MJ,Moossa AR

更新日期：1981-07-01 00:00:00