Platinum analogue combination chemotherapy: cisplatin, carboplatin, and methotrexate in patients with metastatic urothelial tract tumors. A phase II trial with evaluation of prognostic factors.

abstract：:Carcinoembryonic antigen is only a tumor assoicated antigen and is less clinically useful than the original report suggested. However, the CEA assays in clinical use utilize reagents operationally defined by old criteria. There is now abundant evidence that "CEA" consists of a heterogenous family of related glycoprote...

journal_title：Cancer

authors： Alpert E

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:Assessment of tissue specimens obtained with common immersion-fixation followed by dehydration (IMDH) is affected by artifacts, which hinder precise evaluation of the histology and microenvironment of tumor tissues. The technical characteristics of cryobiopsy and in vivo cryotechnique (IVCT) where target org...

journal_title：Cancer

authors： Ohno N,Terada N,Bai Y,Saitoh S,Nakazawa T,Nakamura N,Naito I,Fujii Y,Katoh R,Ohno S

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:This study was conducted to investigate the influence of therapeutic parameters on local control (LC) in the sphincter-conserving treatment of T2-T3 anal carcinoma. METHODS:From 1976 to 1993, 137 patients with anal carcinoma classified as T2 (85 patients) or T3 (52 patients) were treated curatively by radio...

journal_title：Cancer

authors： Allal AS,Mermillod B,Roth AD,Marti MC,Kurtz JM

更新日期：1997-06-15 00:00:00

abstract：:Treatment with BCG (Bacillus Calmette-Guérin) followed by irradiation was attempted to improve response to therapy by cutaneous metastases from malignant skin melanomas. Both agents were applied in low doses, known to cause minimal side effects. Nineteen patients, divided into three groups, entered the clinical trial....

journal_title：Cancer

authors： Plesnicar S,Rudolf Z

更新日期：1982-09-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the value of combined-modality therapy in elderly patients by comparing the differences in outcome between patients who received radiotherapy (RT) alone and patients who received RT plus chemotherapy for stage III nonsmall cell lung cancer (NSCLC). METHODS:The North...

journal_title：Cancer

authors： Schild SE,Mandrekar SJ,Jatoi A,McGinnis WL,Stella PJ,Deming RL,Jett JR,Garces YI,Allen KL,Adjei AA,North Central Cancer Treatment GroupThis study was conducted as a collaborative trial of the North Central Cancer Treatment Group and

更新日期：2007-07-15 00:00:00

abstract：BACKGROUND:Reports utilizing data from the Commission on Cancer's National Cancer Data Base (NCDB) have previously contained evaluations of time trends for stage of disease at diagnosis, treatment, and survival for multiple tumor sites. Data collected from 1989, 1990, 1994, and 1995 for carcinoma of the gallbladder are...

journal_title：Cancer

authors： Donohue JH,Stewart AK,Menck HR

更新日期：1998-12-15 00:00:00

abstract：BACKGROUND:To evaluate the prevalence and significance of abnormal ovarian findings in asymptomatic postmenopausal women, screening for ovarian cancer with color Doppler ultrasound was performed. METHODS:One thousand three hundred sixty-four asymptomatic women aged 56-61 years (mean, 59 years) were examined by color D...

journal_title：Cancer

authors： Vuento MH,Pirhonen JP,Mäkinen JI,Laippala PJ,Grönroos M,Salmi TA

更新日期：1995-10-01 00:00:00

abstract：:The clinicopathologic features of 60 patients with thymic carcinoma were studied. Patients ranged in age from 10 to 76 years (mean, 46), of whom 24 were females and 36 were males. Overall survival at 1, 3, and 5 years was 56.6%, 40%, and 33.3%, respectively. The following morphologic features were correlated with surv...

journal_title：Cancer

authors： Suster S,Rosai J

更新日期：1991-02-15 00:00:00

abstract：BACKGROUND:Trimetrexate is an antifol that differs from methotrexate in ways that may be clinically important. Because methotrexate has activity in advanced bladder cancer, this trial was initiated. METHODS:Ambulatory patients with advanced urothelial carcinoma were treated with the nonclassic antifol trimetrexate at ...

journal_title：Cancer

authors： Witte RS,Elson P,Khandakar J,Trump DL

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:There exist insufficient data characterizing patients with multiple myeloma (MM) who experienced prolonged survival. A population-based analysis of long-term survivors was conducted to investigate the roles of sociodemographic factors and upfront stem cell transplantation (SCT). METHODS:The National Cancer ...

journal_title：Cancer

authors： Hsieh RW,Go RS,Abeykoon JP,Kapoor P,Kumar SK,Gertz MA,Buadi FK,Leung N,Gonsalves WI,Kourelis TV,Warsame RM,Dispenzieri A,Lacy MQ,Kyle RA,Rajkumar SV,Paludo J

更新日期：2019-10-15 00:00:00

abstract：BACKGROUND:Studies of colorectal adenocarcinoma (CRC) indicate a higher mortality rate for African Americans compared with Caucasians in the United States. In the current study, the authors evaluated the racial differences in survival based on tumor location and pathologic stage between African-American patients and Ca...

journal_title：Cancer

authors： Alexander D,Chatla C,Funkhouser E,Meleth S,Grizzle WE,Manne U

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Soft tissue sarcomas of the hand and foot present unique management challenges. The purpose of the current study study was to determine oncologic outcome, particularly with respect to factors affecting local recurrence, distant recurrence, and disease-specific survival. METHODS:A retrospective study was per...

journal_title：Cancer

authors： Lin PP,Guzel VB,Pisters PW,Zagars GK,Weber KL,Feig BW,Pollock RE,Yasko AW

更新日期：2002-08-15 00:00:00

abstract：BACKGROUND:The objective of this Phase II study was to evaluate the concept of sequential chemotherapy in the treatment of patients with advanced nonsmall cell lung carcinoma (NSCLC) by the administration of carboplatin plus gemcitabine followed by of paclitaxel. METHODS:Patients with Stage IIIB (pleural effusion) or ...

journal_title：Cancer

authors： Edelman MJ,Gandara DR,Lau DH,Lara P,Lauder IJ,Tracy D

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:Several states have opted to expand Medicaid under the Patient Protection and Affordable Care Act (ACA), which offers insurance coverage to low-income individuals up to 138% of the federal poverty level. This expansion of Medicaid to a medically vulnerable population potentially can reduce cancer outcome dis...

journal_title：Cancer

authors： Kim U,Koroukian S,Statler A,Rose J

更新日期：2020-09-15 00:00:00

abstract：:Prognostic factors were evaluated in 109 soft tissue sarcomas of the extremities, walls of the trunk, head, and neck. All lesions were graded according to the systems proposed by the National Cancer Institute (NCI) and the French Federation of Cancer Centers (FNCLCC), and a correlation was found between tumor grade an...

journal_title：Cancer

authors： Mandard AM,Petiot JF,Marnay J,Mandard JC,Chasle J,de Ranieri E,Dupin P,Herlin P,de Ranieri J,Tanguy A

更新日期：1989-04-01 00:00:00

abstract：:Chromosome abnormalities from 17 malignancies that were studied using direct preparations and G-, Q-, and C-banding methods are presented and the findings assessed. The material used was from 6 primary cervical carcinomas, 5 primary and metastatic ovarian carcinomas and 6 other metastatic carcinomas. In general, chrom...

journal_title：Cancer

authors： van der Riet-Fox MF,Retief AE,van Niekerk WA

更新日期：1979-12-01 00:00:00

abstract：:The National Wilms' Tumor Study (NWTS) was initiated in 1969. One of its objectives was to modulate treatments according to risk factors to minimize the number and severity of treatment-related short-term and long-term iatrogenic complications. The NWTS has therefore incorporated a Long Term Follow-up Study (LTFS) wit...

journal_title：Cancer

authors： Evans AE,Norkool P,Evans I,Breslow N,D'Angio GJ

更新日期：1991-01-15 00:00:00

abstract：BACKGROUND:A high prevalence of thrombocytosis in malignant mesothelioma has been reported, although its pathogenesis remains unknown. METHODS:The case of a patient with marked thrombocytosis in peritoneal malignant mesothelioma is reported. To investigate the cytokines responsible for thrombocytosis in this patient, ...

journal_title：Cancer

authors： Higashihara M,Sunaga S,Tange T,Oohashi H,Kurokawa K

更新日期：1992-10-15 00:00:00

abstract：BACKGROUND:Serum alpha-L-fucosidase activity is considered a marker of hepatocellular carcinoma. To the authors' knowledge, its clinical usefulness in the early detection of hepatocellular carcinoma in the follow-up of cirrhotic patients has not been reported previously. METHODS:The authors prospectively studied serum...

journal_title：Cancer

authors： Giardina MG,Matarazzo M,Morante R,Lucariello A,Varriale A,Guardasole V,De Marco G

更新日期：1998-12-15 00:00:00

abstract：:Prior studies have shown that black patients with breast cancer have poorer survival times compared with white patients even when adjusted for stage. Seventy-four black patients treated on six Piedmont Oncology Association (POA) protocols were compared with 74 randomly selected white patients treated with the same pro...

journal_title：Cancer

authors： Kimmick G,Muss HB,Case LD,Stanley V

更新日期：1991-06-01 00:00:00

abstract：:Fifteen oncocytic (oxyphilic granular cell) neoplasms of the salivary glands collected from three large university medical centers are presented. The histologic and ultrastructural criteria that characterize oncocytes are presented and electron micrographs of two of our cases are discussed. Included in the series are ...

journal_title：Cancer

authors： Gray SR,Cornog JL Jr,Seo IS

更新日期：1976-09-01 00:00:00

abstract：:Thyroglobulin messenger RNA (mRNA) was located and quantified in tissue sections of differentiated human thyroid cancers by in situ hybridization using cloned complementary DNA probes. The cells of the well-differentiated follicular and papillary forms contained similar levels of thyroglobulin mRNA, corresponding to a...

journal_title：Cancer

authors： Bergé-Lefranc JL,Cartouzou G,De Micco C,Fragu P,Lissitzky S

更新日期：1985-07-15 00:00:00

abstract：:Congenital self-healing histiocytosis (CSHH) is a rare primary histiocytic skin disorder. Only a few cases have been studied by ultrastructure and immunohistochemistry. Here we report a new case that was investigated using an electron microscope and a panel of monoclonal (MCA) and polyclonal (PCA) antibodies. CSHH cel...

journal_title：Cancer

authors： Kanitakis J,Zambruno G,Schmitt D,Cambazard F,Jacquemier D,Thivolet J

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Abnormalities in chromosome 11q13 regions have been frequently found in head and neck squamous carcinoma. Recent studies indicate that the PRAD-1 (also CCND1), which encodes cyclin D1, is a putative oncogene that is an important component of this region. METHODS:DNA was extracted from 32 snap-frozen specime...

journal_title：Cancer

authors： Callender T,el-Naggar AK,Lee MS,Frankenthaler R,Luna MA,Batsakis JG

更新日期：1994-07-01 00:00:00

abstract：:Between September 21, 1973 and May 9, 1975, 36 patients with metastatic cervical adenopathy from cancers primarily arising in the pharynx or oral cavity, including six with bilateral cervical involvement, received fast neutron teletherapy at the University of Washington. At the conclusion of treatment, the masses were...

journal_title：Cancer

authors： Berry HC,Parker RG,Gerdes AJ

更新日期：1976-06-01 00:00:00

abstract：BACKGROUND:Whereas the role of specific symptoms, such as pain and fatigue, for quality of life (QOL) is unquestioned, their relative importance for long-lasting impairments in QOL in cancer patients has rarely been assessed quantitatively. The authors, therefore, aimed to identify symptoms most predictive of limitatio...

journal_title：Cancer

authors： Arndt V,Stegmaier C,Ziegler H,Brenner H

更新日期：2006-11-15 00:00:00

abstract：:To assess the value in Ewing's sarcoma of a new multiagent therapy (vincristine, cyclophosphamide, Adriamycin, (doxorubicin) procarbazine), 30 children with a localized tumor (eight distal, nine proximal, 13 central lesions) treated at the Institut Gustave-Roussy between 1973 and 1976 (E3), were pair-matched by site o...

journal_title：Cancer

authors： Zucker JM,Henry-Amar M,Sarrazin D,Blache R,Patte C,Schweisguth O

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Indium-111 labeled antiferritin targets 95% of all Hodgkin's disease lesions with a diameter of 1 cm or more. Subsequent treatment with yttrium-90 labeled antiferritin secures a high response rate in patients with recurrent Hodgkin's disease. METHODS:A total of 87 patients were entered on one of three diffe...

journal_title：Cancer

authors： Vriesendorp HM,Quadri SM,Andersson BS,Wyllie CT,Dicke KA

更新日期：1997-12-15 00:00:00

abstract：BACKGROUND:The clinical significance of atypical glandular cells of undetermined significance (AGUS) remains poorly understood, and patient management is not standardized. The authors evaluated the rate, qualification, and follow-up (FU) findings of AGUS patients. METHODS:Computerized records from the authors' institu...

journal_title：Cancer

authors： Soofer SB,Sidawy MK

更新日期：2000-08-25 00:00:00

abstract：:One hundred twenty-four patients with seminoma (119 primary testis, five primary extragonadal) were treated between 1968 and 1984 at the Joint Center for Radiation Therapy. Fifty-seven of the 124 patients were treated with irradiation to the mediastinum as well as to an infradiaphragmatic field. One patient received s...

journal_title：Cancer

authors： Lederman GS,Sheldon TA,Chaffey JT,Herman TS,Gelman RS,Coleman CN

更新日期：1987-08-15 00:00:00