Identification of candidate genes carrying polymorphisms associated with the risk of colorectal cancer by analyzing the colorectal mutome and microRNAome.

abstract：:The authors have shown previously that bone marrow transplant (BMT) patients who self-administered bolus doses of morphine gained equal oral mucositis pain relief while using less drug compared with similar patients receiving morphine by staff-controlled continuous infusion. In a follow-up study they compared the effi...

journal_title：Cancer

authors： Hill HF,Mackie AM,Coda BA,Iverson K,Chapman CR

更新日期：1991-02-15 00:00:00

abstract：:Because Forssman antigen, one of the most well-known heteroantigens, has been noted in certain cancerous tissues, it would seem that the serum levels of the Forssman antibody of patients with these cancers would be low, owing to the absorption of the naturally occurring antibody by the Forssman antigen-containing canc...

journal_title：Cancer

authors： Hirayama R,Hirokawa K,Takagi Y,Utsuyama M,Maejima S,Takemura K,Mishima Y,Makinodan T

更新日期：1989-04-15 00:00:00

abstract：:A patient developed widely metastatic adenoid cystic carcinoma of the parotid gland after several local recurrences. A complete regression of pleural, pulmonary parenchymal, cutaneous, and bone metastases was seen following therapy with 5-fluorouracil, Adriamycin, and mitomycin C. This is the second complete response ...

journal_title：Cancer

authors： Budd GT,Groppe CW

更新日期：1983-02-15 00:00:00

abstract：:Merkel cell carcinoma (MCC) is a relatively rare cutaneous malignancy that occurs predominantly in the older white population. The incidence of MCC appears to have tripled during the past 20 years; an increase that is likely to continue because of the growing number of older Americans. The pathogenesis of MCC remains ...

journal_title：Cancer

authors： Bichakjian CK,Lowe L,Lao CD,Sandler HM,Bradford CR,Johnson TM,Wong SL

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Nonionizing radiation, such as radiofrequency field and near infrared laser, induces thermal cytotoxicity in cancer cells treated with gold nanoparticles. Quantum dots are fluorescent semiconducting nanoparticles that were hypothesized to induce similar injury after radiofrequency field irradiation. METHODS...

journal_title：Cancer

authors： Glazer ES,Curley SA

更新日期：2010-07-01 00:00:00

abstract：:Two children with cancer that persisted after multiple exploratory laparotomies, external beam radiation therapy, and multidrug chemotherapy had gold 198 (198Au) seeds implanted into their localized but unresectable tumor. Both children are alive, are receiving no therapy, and are disease-free more than 2 years later....

journal_title：Cancer

authors： Knight PJ,Doornbos JF,Rosen D,Lin JJ,Farha GJ

更新日期：1986-03-01 00:00:00

abstract：:Of 209 Hodgkin's disease patients treated at least 6 months with a five-drug combination of induction chemotherapy and having a complete remission, four patients developed acute myelogenous leukemia (AML) as a second malignant neoplasm. The overall relative risk for development of AML is 185.0 (P less than 0.05) and t...

journal_title：Cancer

authors： Bartolucci AA,Liu C,Durant JR,Gams RA

更新日期：1983-12-15 00:00:00

abstract：:This report documents, in seven infants younger than 2 years of age, a previously unrecognized association of a renal embryonal neoplasm (malignant rhabdoid tumor in six patients and a Wilms' tumor in one) with an embryonal primary tumor originating in the central nervous system. The neuroepithelial tumors included th...

journal_title：Cancer

authors： Bonnin JM,Rubinstein LJ,Palmer NF,Beckwith JB

更新日期：1984-11-15 00:00:00

abstract：BACKGROUND:It remains unclear whether health-related quality of life (HRQoL) measurements from patients and staff can be combined with medical data to predict survival in patients with terminal cancer. METHODS:The correlations between survival and potential health-related quality-of-life (HRQoL) prognostic variables w...

journal_title：Cancer

authors： Vigano A,Donaldson N,Higginson IJ,Bruera E,Mahmud S,Suarez-Almazor M

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Despite significant advances in understanding the biology of renal cell carcinoma (RCC) during the past decade, metastatic disease remains nearly incurable and a major medical challenge. Because RCC is known to be immunogenic, immunotherapeutic agents such as recombinant human interleukin-2 (rIL-2) and inter...

journal_title：Cancer

authors： Bukowski RM

更新日期：1997-10-01 00:00:00

abstract：:The clinical presentation of the disease and the results of treatment in 42 patients with malignant peripheral neuroectodermal tumors (MPNT) entered into the Cooperative Ewing's, soft tissue, and neuroblastoma trials of the German Society of Pediatric Oncology were retrospectively analyzed. Within the Ewing's sarcoma ...

journal_title：Cancer

authors： Jürgens H,Bier V,Harms D,Beck J,Brandeis W,Etspüler G,Gadner H,Schmidt D,Treuner J,Winkler K

更新日期：1988-01-15 00:00:00

abstract：:Pel-Epstein fever cycles, consisting of 1-2 weeks of high fever separated by afebrile periods of the same duration, are classically characteristic of Hodgkin's disease. Clinical observation has determined that the lymph nodes enlarge during periods of fever and reduce in size as the fever subsides. To our knowledge, t...

journal_title：Cancer

authors： Scanlon GT,Castellino RA,Rudders R

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Recently, peripheral lung adenocarcinomas (PLA) measuring < or = 3 cm in greatest dimension often have been diagnosed using diagnostic radiology. The objective of the current study was to determine which cytologic factors are associated with a favorable outcome and an unfavorable outcome in patients with PLA...

journal_title：Cancer

authors： Kobayashi Y,Yokose T,Kawamura K,Iwasaki S,Murata Y,Onuma S,Hasebe T,Nagai K,Sasaki S,Ochiai A

更新日期：2005-02-25 00:00:00

abstract：BACKGROUND:The human papillomavirus (HPV) E2 protein is a transcriptional repressor of the oncogenes E6/E7 and loss of E2 function is considered a key step in carcinogenesis. Integration of HPV into the host genome may disrupt the E2 gene. Furthermore, methylation of CpG dinucleotides in E2-binding sites (E2BSs) in the...

journal_title：Cancer

authors： Reuschenbach M,Huebbers CU,Prigge ES,Bermejo JL,Kalteis MS,Preuss SF,Seuthe IM,Kolligs J,Speel EJ,Olthof N,Kremer B,Wagner S,Klussmann JP,Vinokurova S,von Knebel Doeberitz M

更新日期：2015-06-15 00:00:00

abstract：:A strong activity of the tartrate-resistant acid phosphatase, isoenzyme 5b, was observed in mouse spleen. The enzyme of the mouse spleen had similar electrophoretic mobility and related antigenicity to that of the reticulum cells of leukemic reticuloendotheliosis. Enzyme histochemical studies showed many non-phagocyti...

journal_title：Cancer

authors： Kuehler D,Lam KW,Yam LT

更新日期：1981-02-15 00:00:00

abstract：:Epidemiologic and laboratory data suggest that cervical cancer typically arises from a series of causal steps. Each step can be studied separately in the hope of better etiologic understanding and improved cancer prevention. The earliest identified etiologic step is infection of young women with specific types of vene...

journal_title：Cancer

authors： Schiffman MH,Brinton LA

更新日期：1995-11-15 00:00:00

abstract：:The prognostic value of nuclear DNA content was studied retrospectively using flow cytometry in 203 cases of resected hepatocellular carcinoma. The occurrence of DNA aneuploidy, which was detected in 50% of patients, correlated significantly with tumor size and the presence of vascular invasion or intrahepatic metasta...

journal_title：Cancer

authors： Fujimoto J,Okamoto E,Yamanaka N,Toyosaka A,Mitsunobu M

更新日期：1991-02-15 00:00:00

abstract：:First implemented in 1990, patient navigation interventions are emerging today as an approach to reduce cancer disparities. However, there is lack of consensus about how patient navigation is defined, what patient navigators do, and what their qualifications should be. Little is known about the efficacy and cost-effec...

journal_title：Cancer

authors： Wells KJ,Battaglia TA,Dudley DJ,Garcia R,Greene A,Calhoun E,Mandelblatt JS,Paskett ED,Raich PC,Patient Navigation Research Program.

更新日期：2008-10-15 00:00:00

abstract：:With endometrial adenocarcinoma, several factors, such as stage and histologic grade, are well recognized as having prognostic significance. Other variables, e.g., nuclear grade, probably are also important clinically. A preliminary investigation of the prognostic value of the ploidy, cell cycle kinetics, and sex ster...

journal_title：Cancer

authors： Geisinger KR,Homesley HD,Morgan TM,Kute TE,Marshall RB

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Patients with advanced cancer often experience fatigue and other symptoms that negatively impact their quality of life. The current trial investigated the effect of melatonin on fatigue and other symptoms in patients with advanced cancer. METHODS:Patients who were aged ≥18 years, had a histologically confir...

journal_title：Cancer

authors： Lund Rasmussen C,Klee Olsen M,Thit Johnsen A,Petersen MA,Lindholm H,Andersen L,Villadsen B,Groenvold M,Pedersen L

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:Childhood cancer survivors are at risk for cardiovascular disease (CVD) because of intensive cancer therapies often accompanied by an unhealthy lifestyle. This study was aimed at 1) describing modifiable CVD risk factors in survivors and 2) investigating the association between different aspects of physical ...

journal_title：Cancer

authors： Schindera C,Zürcher SJ,Jung R,Boehringer S,Balder JW,Rueegg CS,Kriemler S,von der Weid NX

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:Modern cancer treatments can cure or prolong patients' lives. However, the associated physical and psychosocial problems can detrimentally affect patients' compliance with treatment and, ultimately, their outcomes. Therefore, oncologists need to recognize the problems experienced by their patients and, when ...

journal_title：Cancer

authors： Newell S,Sanson-Fisher RW,Girgis A,Bonaventura A

更新日期：1998-10-15 00:00:00

abstract：:Three patients had supratentorial malignant brain tumors 7 to 9 years after prophylactic central nervous system (CNS) treatment for acute lymphocytic leukemia or malignant T-cell lymphoma. Therapy was administered at the age of 3 to 8 years and included cranial irradiation (total dose, 1800 to 2400 cGy) and intratheca...

journal_title：Cancer

authors： Brüstle O,Ohgaki H,Schmitt HP,Walter GF,Ostertag H,Kleihues P

更新日期：1992-05-01 00:00:00

abstract：:The role of 99mTc-pertechnetate thyroid imaging in the preoperative assessment of patients with single palpable thyroid nodules was evaluated. The frequency of cancer in hypofunctional nodules was similar to that found in previous studies with 131I. The 99mTc-pertechnetate image allowed a reliable separation of pathol...

journal_title：Cancer

authors： Alderson PO,Sumner HW,Siegel BA

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Cervical carcinoma remains a significant health risk for the older woman. In the current study the yield of screening of mature women in an established, opportunistic screening program was examined. Strategies for improving screening in this age group were identified through examination of recent Pap test hi...

journal_title：Cancer

authors： Colgan TJ,Clarke A,Hakh N,Seidenfeld A

更新日期：2002-08-25 00:00:00

abstract：BACKGROUND:Inhibition of the hedgehog signaling pathway (HHSP) for the treatment of locally advanced basal cell carcinoma (BCC) and metastatic BCC (mBCC) has produced promising results. Typically, mBCC is not taken into consideration during the workup of a patient with multifocal metastatic disease who has a history of...

journal_title：Cancer

authors： Weiss GJ,Korn RL

更新日期：2012-11-01 00:00:00

abstract：:The cytogenetic findings in 31 liposarcomas from 26 patients are reported. Four other tumors did not grow. Three histologic types are represented in this analysis. The well-differentiated liposarcomas were characterized by telomeric associations, large marker chromosomes and ring chromosomes, and in some cases, double...

journal_title：Cancer

authors： Sreekantaiah C,Karakousis CP,Leong SP,Sandberg AA

更新日期：1992-05-15 00:00:00

abstract：:A prospective study of patients receiving cis-diaminedichloroplatin II (DDP) was carried out to determine if risk factors could be identified related to the patient's living habits or past medical history that would predict in which patients DDP neuropathy might develop. Sixty-nine patients receiving six different com...

journal_title：Cancer

authors： Mollman JE,Glover DJ,Hogan WM,Furman RE

更新日期：1988-06-01 00:00:00

abstract：:Clinical and pharmacokinetic studies were performed regarding the toxicity of methyl 6-[3-(2-chloroethyl)-3-nitrosoureido]-6-deoxy-alpha-D-glucopyranoside (MCNU) with other drugs, in conjunction with a peripheral blood stem cell autograft (PBSCT), for treating 26 children with acute leukemia or lymphoma associated wit...

journal_title：Cancer

authors： Takaue Y,Watanabe T,Hoshi Y,Abe T,Matsunaga K,Saito S,Hirao A,Kawano Y,Ninomiya T,Kuroda Y

更新日期：1991-04-01 00:00:00

abstract：:The clinical findings in 262 patients with melanoma were correlated with an assessment of their cellular-mediated immunity by delayed-type hypersensitivity (DTH) skin tests, by lymphocyte blastogenesis, and by leukocyte enumerations. Patients with systemic metastases (stage IV) and those with evidence of tumor burden ...

journal_title：Cancer

authors： Pritchard DJ,Ritts RE Jr,Taylor WF,Miller GC

更新日期：1978-06-01 00:00:00