Management of low-grade gliomas of the optic nerve and chiasm.

Abstract:

:Thirty-six patients were evaluated between 1965 and 1983 for glioma of the optic nerves and/or chiasm. Median follow-up was 10.2 years. Pathologic verification was obtained in 32 patients. Tumor initially confined to the optic nerve recurred in one of five patients after complete resection. The actuarial survival for 25 patients irradiated for biopsy-proven glioma of the optic chiasm was 96%, 90%, and 90% at 5, 10, and 15 years, respectively, and the progression-free survival was 87% at 5, 10, and 15 years. Vision stabilized or improved in 86% of patients after radiotherapy. Patients irradiated to a dose greater than a NSD of 1385 ret had a significantly improved progression-free survival (P = 0.015). One serious complication occurred after a dose of 1533 ret. The recommended radiation dose for optic glioma is 45 to 50 Gy with 1.8 Gy fractions.

journal_name

Cancer

journal_title

Cancer

authors

Flickinger JC,Torres C,Deutsch M

doi

10.1002/1097-0142(19880215)61:4<635::aid-cncr28206

subject

Has Abstract

pub_date

1988-02-15 00:00:00

pages

635-42

issue

4

eissn

0008-543X

issn

1097-0142

journal_volume

61

pub_type

杂志文章

相关文献

CANCER文献大全
  • Demonstration of Chromogranin A in human neuroendocrine cell lines by immunohistology and immunoassay.

    abstract::We have used immunohistology and radioimmunoassay procedures to study Chromogranin A (CgA) in human neuroendocrine tumor cell lines, especially small cell lung cancers (SCLC). By immunohistology, CgA could be detected in 11 of 18 classical SCLC cell lines, in a medullary thyroid carcinoma (MTC) cell line, and in only ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19880701)62:1<92::aid-cncr282062

    authors: Deftos LJ,Linnoila RI,Carney DN,Burton DW,Leong SS,O'Connor DT,Murray SS,Gazdar AF

    更新日期:1988-07-01 00:00:00

  • A human liposarcoma cell line producing hyaluronic acid.

    abstract::A human liposarcoma cell line COLO 222, derived from a primary tumor in a 62-year-old male, elaborates hyaluronic acid. COLO 222 is characterized on the basis of histochemical, ultramorphological, and cytogenetic properties, along with isozyme phenotype and cell products. A chromosome mode of 53 predominates and uniqu...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19800315)45:6<1400::aid-cncr2820

    authors: Morgan RT,Quinn LA,Moore GE,Semple TU,Woods LK

    更新日期:1980-03-15 00:00:00

  • Nutrition and diet in the etiology of endometrial cancer.

    abstract::The risk of endometrial cancer in relation to nutrition and frequency of consumption of a few selected dietary items was evaluated in a case-control study of 206 patients with endometrial cancer and 206 control subjects with acute conditions unrelated to any of the established or potential risk factors for endometrial...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19860315)57:6<1248::aid-cncr2820

    authors: La Vecchia C,Decarli A,Fasoli M,Gentile A

    更新日期:1986-03-15 00:00:00

  • Effects of high-intensity aerobic interval training on cardiovascular disease risk in testicular cancer survivors: A phase 2 randomized controlled trial.

    abstract:BACKGROUND:Testicular cancer survivors (TCS) have an increased risk of treatment-related cardiovascular disease (CVD), which may limit their overall survival. We evaluated the effects of high-intensity aerobic interval training (HIIT) on traditional and novel CVD risk factors and surrogate markers of mortality in a pop...

    journal_title:Cancer

    pub_type: 杂志文章,随机对照试验

    doi:10.1002/cncr.30859

    authors: Adams SC,DeLorey DS,Davenport MH,Stickland MK,Fairey AS,North S,Szczotka A,Courneya KS

    更新日期:2017-10-15 00:00:00

  • Pretreatment and routine echocardiogram monitoring during chemotherapy for anthracycline-induced cardiotoxicity rarely identifies significant cardiac dysfunction or alters treatment decisions: a 5-year review at a single pediatric oncology center.

    abstract:BACKGROUND:The widespread use of anthracycline chemotherapy has contributed to improved outcomes in children with cancer. The most feared complication of the anthracyclines is cardiotoxicity. Routine echocardiographic monitoring typically is used before, during, and after treatment to minimize cardiotoxicity. The ideal...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26481

    authors: Watts RG,George M,Johnson WH Jr

    更新日期:2012-04-01 00:00:00

  • Bone marrow magnetic resonance studies in childhood leukemia. Evaluation of osteonecrosis.

    abstract::In 25 patients under treatment or during follow-up for acute lymphoblastic leukemia magnetic resonance imaging (MRI) of both knees was compared to history and physical examination to detect osteonecrosis. Results of MRI were classified as: O, normal bone marrow (BM); 1, diffuse decrease in signal intensity; 2, circums...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19871215)60:12<2994::aid-cncr282

    authors: Pieters R,van Brenk AI,Veerman AJ,van Amerongen AH,van Zanten TE,Golding RP

    更新日期:1987-12-15 00:00:00

  • The impact of early resection of primary neuroblastoma on the survival of children older than 1 year of age with stage 4 disease: the St. Jude Children's Research Hospital Experience.

    abstract:BACKGROUND:It remains unclear whether primary tumor resection benefits patients with metastatic neuroblastoma. The authors assessed the impact of extent and timing of resection on outcome in these patients. METHODS:The authors reviewed the records of 124 patients > 1 year of age at diagnosis of International Neuroblas...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21566

    authors: McGregor LM,Rao BN,Davidoff AM,Billups CA,Hongeng S,Santana VM,Hill DA,Fuller C,Furman WL

    更新日期:2005-12-15 00:00:00

  • Preclinical and clinical studies of interferons and interferon inducers in breast cancer.

    abstract::Preclinical and clinical studies suggest interferons and interferon inducers have antitumor activity for breast carcinoma. Observations include inhibition of growth of freshly derived and continuously passaged breast carcinoma cells in vitro, decreased tumor size and increased survival in spontaneous mouse mammary car...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19840201)53:3+<783::aid-cncr2820

    authors: Borden EC,Balkwill FR

    更新日期:1984-02-01 00:00:00

  • Cisplatin, vindesine and bleomycin (CVB) combination chemotherapy of advanced non-small cell lung cancer.

    abstract::Fifty-four patients with advanced squamous, large-cell or adeno-carcinoma of the lung were treated with a three drug regimen of high-dose cisplatin, vindesine and a four-day bleomycin infusion (CVB). All patients had measurable disease; none had previously received chemotherapy. Of 52 patients evaluable for response, ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19830315)51:6<1050::aid-cncr2820

    authors: Itri LM,Gralla RJ,Kelsen DP,Chapman RA,Casper ES,Braun DW Jr,Howard JE,Golbey R,Heelan RT

    更新日期:1983-03-15 00:00:00

  • A simple rapid autoradiography for 3H-thymidine labeling index and its application to therapy of adult acute leukemia.

    abstract::Our simple rapid autoradiography for 3H-thymidine (3H-TdR) labeling index (LI) of leukemic cells was introduced. Thirty-nine adult patients with acute nonlymphocytic leukemia were treated under a new protocol using 3H-TdR LI as a parameter and inserting a trial of partial synchronization by Ara-C. The success rate of ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19801115)46:10<2298::aid-cncr282

    authors: Yoshida T,Hattori KI,Nakamura S,Mitamura E,Kobayashi S,Ohtake S,Tanimoto K

    更新日期:1980-11-15 00:00:00

  • Significance and possible causes of false-negative results of reflex human Papillomavirus infection testing.

    abstract:BACKGROUND:The objective of this study was to assess the rate and possible reasons for false-negative (FN) reflex human papillomavirus (HPV)-DNA tests. METHODS:The authors reviewed all ThinPrep cervical specimens that were submitted for reflex HPV-DNA testing using the Digene Hybrid Capture II (HC2) method from Januar...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.22688

    authors: Eltoum IA,Chhieng DC,Crowe DR,Roberson J,Jin G,Broker TR

    更新日期:2007-06-25 00:00:00

  • Work-related medical rehabilitation in patients with cancer-Postrehabilitation results from a cluster-randomized multicenter trial.

    abstract:BACKGROUND:Effective multidisciplinary rehabilitation programs supporting the return to work have become increasingly relevant for cancer survivors. In Germany, inpatient work-related medical rehabilitation programs consider treatment modules of work-related diagnostics, work-related functional capacity training, psych...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1002/cncr.32131

    authors: Fauser D,Wienert J,Beinert T,Schmielau J,Biester I,Krüger HU,Presl A,Bethge M

    更新日期:2019-08-01 00:00:00

  • A phase II study of bortezomib in the treatment of metastatic malignant melanoma.

    abstract:BACKGROUND:Bortezomib is a proteasome inhibitor with manageable clinical toxicity and laboratory evidence of anti-melanoma activity. Therefore, it was considered for clinical testing in patients with metastatic melanoma. METHODS:Patients with metastatic melanoma and adequate hematologic, renal, and hepatic function we...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/cncr.21108

    authors: Markovic SN,Geyer SM,Dawkins F,Sharfman W,Albertini M,Maples W,Fracasso PM,Fitch T,Lorusso P,Adjei AA,Erlichman C

    更新日期:2005-06-15 00:00:00

  • Occult hepatitis B virus infection is associated with the development of hepatocellular carcinoma in chronic hepatitis C patients.

    abstract:BACKGROUND:Occult hepatitis B virus (HBV) infection frequently occurs in patients with HBV surface antigen (HBsAg)-negative chronic liver disease, and much evidence suggests that it is a risk factor for hepatocellular carcinoma (HCC) development. However, to the authors' knowledge, no follow-up study has been performed...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.21702

    authors: Squadrito G,Pollicino T,Cacciola I,Caccamo G,Villari D,La Masa T,Restuccia T,Cucinotta E,Scisca C,Magazzu D,Raimondo G

    更新日期:2006-03-15 00:00:00

  • Flexible fiberoptic bronchoscopy in metastatic cancer to the lungs.

    abstract::Seventy-eight patients with metastatic cancer to the lungs underwent flexible fiberoptic bronchoscopy for diagnosis. The patients were divided into two groups by presenting radiographic pattern as: (I) diffuse linear interstitial infiltrations (55 patients); and (II) localized or multiple nodular opacities (23 patient...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19831115)52:10<1949::aid-cncr282

    authors: Chuang MT,Padilla ML,Teirstein AS

    更新日期:1983-11-15 00:00:00

  • High dose methotrexate followed by citrovorum factor reversal in patients with advanced cancer.

    abstract::High dose methotrexate followed by citrovorum factor reversal has been utilized in twenty-six patients with advanced cancer. Four of 10 patients with head and neck cancer had an objective response. One of 7 patients with metastatic osteosarcoma to the lungs had stabilization with twenty treatments over 23 months. One ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197904)43:4<1177::aid-cncr282043

    authors: Ambinder EP,Perloff M,Ohnuma T,Biller HF,Holland JF

    更新日期:1979-04-01 00:00:00

  • Biologic distinctions between cure and time to death in 2892 patients with intraocular melanoma.

    abstract:BACKGROUND:For certain types of cancer, resection alone rarely achieves a cure, but patients nevertheless tend to have a prolonged survival before they die of the tumor. For other types of cancer, the opposite scenario prevails, suggesting that those biologic mechanisms that allow a curative resection are not identical...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19930401)71:7<2299::aid-cncr2820

    authors: Gamel JW,McLean IW,McCurdy JB

    更新日期:1993-04-01 00:00:00

  • Prospective assessment of emotional distress, cognitive function, and quality of life in patients with cancer treated with chemotherapy.

    abstract:BACKGROUND:The current study sought to delineate prospectively the rates and clinical course of emotional distress, cognitive impairment, and quality of life (QOL) in chemotherapy-naive patients with cancer and to consider the determinants of global QOL. METHODS:Patients who consented to participate were administered ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20385

    authors: Iconomou G,Mega V,Koutras A,Iconomou AV,Kalofonos HP

    更新日期:2004-07-15 00:00:00

  • Is thyroidectomy necessary in RET mutations carriers of the familial medullary thyroid carcinoma syndrome?

    abstract:BACKGROUND:The results and consequences of genetic testing in a family with familial medullary thyroid carcinoma (FMTC) are described. METHODS:In the screening of relatives, serum calcitonin is replaced by RET mutation analysis that was performed in families suspected of hereditary medullary thyroid carcinoma (MTC). I...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Hansen HS,Torring H,Godballe C,Jäger AC,Nielsen FC

    更新日期:2000-08-15 00:00:00

  • Overcoming sociodemographic factors in the care of patients with testicular cancer at a safety net hospital.

    abstract:BACKGROUND:The objective of this study was to determine whether standardized treatment of germ cell tumors (GCTs) could overcome sociodemographic factors limiting patient care. METHODS:The records of all patients undergoing primary treatment for GCTs at both a public safety net hospital and an academic tertiary care c...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.33076

    authors: Chertack N,Ghandour RA,Singla N,Freifeld Y,Hutchinson RC,Courtney K,Bowman IA,Arafat W,Meng X,Moore JA,Aydin AM,Sagalowsky AI,Margulis V,Lotan Y,Woldu SL,Bagrodia A

    更新日期:2020-10-01 00:00:00

  • Increased lipid peroxidation in malignant tissues of patients with colorectal cancer.

    abstract::The authors investigated the level of lipid peroxidation and possible related phenomena in the activation of phospholipase A2 and the infiltration of granulocyte neutrophils in human colorectal cancer tissue samples. Malondialdehyde (an index of lipid peroxidation), phospholipase A2 activity, and myeloperoxidase activ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19890715)64:2<422::aid-cncr28206

    authors: Otamiri T,Sjödahl R

    更新日期:1989-07-15 00:00:00

  • Colorectal carcinoma cell production of transforming growth factor beta decreases expression of endothelial cell vascular endothelial growth factor receptor 2.

    abstract:BACKGROUND:Vascular endothelial growth factor (VEGF) signaling is a target for antiangiogenic cancer therapy. The authors have previously observed that up to 40% of vessels in colorectal carcinoma (CRC) tumors are negative for VEGF receptor 2 (VEGFR2) expression. Differential activity of transforming growth factor beta...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.26247

    authors: Kuczynski EA,Viloria-Petit AM,Coomber BL

    更新日期:2011-12-15 00:00:00

  • Primary adenocarcinoma of the urinary bladder. A clinicopathologic and prognostic study.

    abstract::The study is a clinicopathologic report on 64 patients with primary adenocarcinoma of the urinary bladder and urachus, with particular reference to important prognostic and therapeutic factors. All tumors exhibited adenocarcinomatous features in at least two thirds of the examined tumor area. Pure forms of the differe...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(19831001)52:7<1273::aid-cncr2820

    authors: Anderström C,Johansson SL,von Schultz L

    更新日期:1983-10-01 00:00:00

  • Modern prostate brachytherapy. Prostate specific antigen results in 219 patients with up to 12 years of observed follow-up.

    abstract:BACKGROUND:The purported lack of long term modern prostate brachytherapy outcome data continues to lead many physicians to recommend other, more traditional treatments. This concern for long term results has encouraged the authors to supplement their earlier 10-year follow-up of patients receiving brachytherapy; in the...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:

    authors: Ragde H,Korb LJ,Elgamal AA,Grado GL,Nadir BS

    更新日期:2000-07-01 00:00:00

  • A phase 2 study of cetuximab in combination with docetaxel in chemotherapy-refractory/resistant patients with advanced nonsmall cell lung cancer.

    abstract:BACKGROUND:Cetuximab in combination with docetaxel was examined in chemotherapy-refractory/resistant patients with advanced nonsmall-cell lung cancer (NSCLC) to determine response rate, survival, safety, and pharmacokinetics (PK). METHODS:Patients had evidence of epidermal growth factor receptor (EGFR) expression (> o...

    journal_title:Cancer

    pub_type: 杂志文章,多中心研究

    doi:10.1002/cncr.24148

    authors: Kim ES,Mauer AM,William WN Jr,Tran HT,Liu D,Lee JJ,Windt P,Hong WK,Vokes EE,Herbst RS

    更新日期:2009-04-15 00:00:00

  • Non-Hodgkin's lymphoma: patterns of relapse from complete remission after combination chemotherapy.

    abstract::An analysis of patterns of relapse from complete remission in patients with non-Hodgkin's lymphoma treated with combination chemotherapy has demonstrated differences between histologic subgroups. Patients with diffuse histiocytic lymphoma who achieved a histologically proven complete remission after 6 months of treatm...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197502)35:2<354::aid-cncr2820350

    authors: Schein PS,Chabner BA,Canellos GP,Young RC,DeVita VT Jr

    更新日期:1975-02-01 00:00:00

  • Combination therapy for anaplastic giant cell thyroid carcinoma.

    abstract::Since 1981, 20 patients with anaplastic giant cell carcinoma of the thyroid have been prospectively treated according to a combination regimen of chemotherapy and external beam radiation therapy. Two types of chemotherapy were used every 4 weeks, depending on the patient's age. For those younger than 65 years, a combi...

    journal_title:Cancer

    pub_type: 临床试验,杂志文章

    doi:10.1002/1097-0142(19910201)67:3<564::aid-cncr28206

    authors: Schlumberger M,Parmentier C,Delisle MJ,Couette JE,Droz JP,Sarrazin D

    更新日期:1991-02-01 00:00:00

  • Ultrasonic imaging of neoplasms.

    abstract::Reflected ultrasound scanning (echography) is rapidly developing into a prime tool for tumor diagnosis, outlining, and detection. The principles of echographic diagnosis of neoplasms, the accepted uses in detection and diagnosis, as well as some of the principles of internal and contour patterns are discussed. Echogra...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197601)37:1+<496::aid-cncr282037

    authors: Freimanis AK

    更新日期:1976-01-01 00:00:00

  • Mental disorders in cancer patients: a study of 100 psychiatric referrals.

    abstract::Records of 100 consecutive hospitalized cancer patients referred for psychiatric consultation were reviewed. These patients constituted only 5% of those seen by the Psychiatry Consultation Service during the study period. Fifty-six percent of the referred patients were diagnosed as depressed and 40% as having organic ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/1097-0142(197809)42:3<1385::aid-cncr282042

    authors: Levine PM,Silberfarb PM,Lipowski ZJ

    更新日期:1978-09-01 00:00:00

  • Depression, cigarette smoking, and hematopoietic stem cell transplantation outcome.

    abstract:BACKGROUND:The relationships between psychological and behavioral variables and patient outcomes after hematopoietic stem cell transplantation (HSCT) are not known definitively but have great potential importance, since this lifesaving procedure is used increasingly to treat a variety of malignancies. The objective of ...

    journal_title:Cancer

    pub_type: 杂志文章

    doi:10.1002/cncr.20431

    authors: Chang G,Orav EJ,McNamara T,Tong MY,Antin JH

    更新日期:2004-08-15 00:00:00