The treatment of Wilms' tumor: results of the Second National Wilms' Tumor Study.

abstract：BACKGROUND:None of the commonly used staging criteria accurately determine the prognosis of a patient with adenocarcinoma of Barrett's esophagus. The authors therefore assessed the expression pattern and prognostic impact of CD44 standard and CD44 isoforms CD44v4, v5,v6,v7, and v10 in adenocarcinoma of Barrett's esopha...

journal_title：Cancer

authors： Böttger TC,Youssef V,Dutkowski P,Maschek H,Brenner W,Junginger T

更新日期：1998-09-15 00:00:00

abstract：BACKGROUND:The objective of this study was to evaluate the efficacy and toxicity of a high-dose 5-fluorouracil and actinomycin D regimen (the FA regimen) as salvage chemotherapy for patients with high-risk gestational trophoblastic tumors (GTTs). METHODS:From 1985 to 1997, 10 patients with refractory, high-risk GTTs w...

journal_title：Cancer

authors： Matsui H,Suzuka K,Iitsuka Y,Yamazawa K,Tanaka N,Mitsuhashi A,Seki K,Sekiya S

更新日期：2002-09-01 00:00:00

abstract：BACKGROUND:The distinction of sporadic from inherited medullary thyroid carcinomas (MTCs) is of clinical importance because of the differences in prognosis, and the need for family screening for genetic counseling required in the latter. Germline mutations in the RET protooncogene are associated with multiple endocrine...

journal_title：Cancer

authors： Komminoth P,Kunz EK,Matias-Guiu X,Hiort O,Christiansen G,Colomer A,Roth J,Heitz PU

更新日期：1995-08-01 00:00:00

abstract：:DNA ploidy and percent of (%S-phase) S-phase cells were determined from the DNA content distribution of 21 benign and 76 malignant (69 primary, 7 metastatic) breast tumors using flow cytometry. All of the benign tumors were diploid, whereas 89% of the malignant tumors had measurable aneuploidy. Multiple stem-lines wer...

journal_title：Cancer

authors： Moran RE,Black MM,Alpert L,Straus MJ

更新日期：1984-10-15 00:00:00

abstract：:The authors describe two cases of Fournier's gangrene complicating aggressive therapy for hematologic malignancies. Fournier's gangrene is a fulminant necrotizing fasciitis of the scrotum and penis, often with an infectious etiology. Only one prior case has been reported in a patient receiving aggressive chemotherapy ...

journal_title：Cancer

authors： Berg A,Armitage JO,Burns CP

更新日期：1986-06-15 00:00:00

abstract：BACKGROUND:To the authors' knowledge, there is no standard treatment for patients with T-cell large granular lymphocyte (LGL) leukemia. Available data are limited by patient numbers and coexisting pathologies. METHODS:The authors report on the use of immunosuppressants (cyclosporin A [CSA] and low-dose oral methotrexa...

journal_title：Cancer

authors： Osuji N,Matutes E,Tjonnfjord G,Grech H,Del Giudice I,Wotherspoon A,Swansbury JG,Catovsky D

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:The months immediately after the completion of treatment for childhood acute lymphoblastic leukemia (ALL) are often regarded as a stressful time for children and families. In this prospective, longitudinal study, the prevalence and predictors of anxiety and depressive symptoms after the completion of treatme...

journal_title：Cancer

authors： Kunin-Batson AS,Lu X,Balsamo L,Graber K,Devidas M,Hunger SP,Carroll WL,Winick NJ,Mattano LA Jr,Maloney KW,Kadan-Lottick NS

更新日期：2016-05-15 00:00:00

abstract：BACKGROUND:This study was performed to evaluate the effect of positive margins, Gleason grade, and capsular penetration on progression after radical prostatectomy. METHODS:The authors followed 507 men with totally embedded retropubic prostatectomy specimens performed for clinical Stages A and B prostate cancer for a m...

journal_title：Cancer

authors： Epstein JI,Pizov G,Walsh PC

更新日期：1993-06-01 00:00:00

abstract：:Six hundred fifty-eight cases of previously untreated non-Hodgkin's lymphoma seen between 1970 and 1979 at the Medical Department, the Finsen Institute, were the basis for a comparative study of the prognostic value of the Rappaport, Kiel, and Lukes & Collins classifications and the new translation system, the Working...

journal_title：Cancer

authors： Ersbøll J,Schultz HB,Hougaard P,Nissen NI,Hou-Jensen K

更新日期：1985-05-15 00:00:00

abstract：BACKGROUND:In the current study, the authors focused on determinants influencing the quality of care and variations in the actual quality of integrated care for patients with nonsmall cell lung cancer (NSCLC) to estimate whether there is room for improvement. METHODS:The authors tested the quality of integrated care f...

journal_title：Cancer

authors： Ouwens MM,Hermens RR,Termeer RA,Vonk-Okhuijsen SY,Tjan-Heijnen VC,Verhagen AF,Hulscher MM,Marres HA,Wollersheim HC,Grol RP

更新日期：2007-10-15 00:00:00

abstract：BACKGROUND:Even when they are analogous in microscopic and macroscopic appearance, tumors vary in their response rates to radiotherapy. Cell culture and xenograft experiments with colorectal cell lines have demonstrated that wild-type p53 increases radiosensitivity. Hence, the authors investigated, in a well-defined po...

journal_title：Cancer

authors： Nehls O,Klump B,Holzmann K,Lammering G,Borchard F,Gruenagel HH,Gaco V,Gregor M,Porschen R

更新日期：1999-06-15 00:00:00

abstract：BACKGROUND:The authors hypothesized that the outcomes for young patients who present with primary osteosarcoma of flat bones or secondary osteosarcoma after other primary malignancies are similar because the sites of these tumors rarely makes them amenable to complete surgical resection. METHODS:The authors reviewed t...

journal_title：Cancer

authors： Pratt CB,Meyer WH,Rao BN,Pappo AS,Fleming ID,Luo X,Cain A,Kaste SC,Shearer PD,Jenkins JJ 3rd

更新日期：1997-09-15 00:00:00

abstract：BACKGROUND:This study was conducted to determine if pelvic computed tomography (CT) should routinely be appended to abdominal CT in the workup of patients with breast carcinoma. METHODS:The abdominal-pelvic CTs of 139 breast carcinoma patients (195 exams) were reviewed. Scans were grouped by indication and whether pel...

journal_title：Cancer

authors： Meyer JI,Herts BR,Einstein DM,Singer AA,Budd GT,Cohen MA

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND:In the phase 3 MARIANNE trial, trastuzumab emtansine (T-DM1) with or without pertuzumab showed noninferior progression-free survival and better tolerability than trastuzumab plus a taxane (HT) for the first-line treatment of human epidermal growth factor receptor 2 (HER2)-positive advanced breast cancer. Thi...

journal_title：Cancer

authors： Perez EA,Barrios C,Eiermann W,Toi M,Im YH,Conte P,Martin M,Pienkowski T,Pivot XB,Burris HA 3rd,Petersen JA,De Haas S,Hoersch S,Patre M,Ellis PA

更新日期：2019-11-15 00:00:00

abstract：:"Bowen's disease" is a clinical and histologic diagnosis describing the lesions (single or multiple) of cutaneous in situ squamous cell carcinoma. The case of a 54-year-old man with 60 such intra-epidermal carcinomas, and a history of arsenic ingestion, is presented. The patient was sensitized to dinitrochlorobenzene ...

journal_title：Cancer

authors： Raaf JH,Krown SE,Pinsky CM,Cunningham-Rundles W,Safai B,Oettgen HF

更新日期：1976-04-01 00:00:00

abstract：BACKGROUND:Improvements in quality of life after treatment with recombinant human erythropoietin (rHuEPO) often have been reported in patients with end-stage renal disease. In patients with chronic anemia of cancer, comparatively few systemic investigations have been performed. METHODS:Various aspects of quality of li...

journal_title：Cancer

authors： Leitgeb C,Pecherstorfer M,Fritz E,Ludwig H

更新日期：1994-05-15 00:00:00

abstract：:Thirty-nine untreated patients with either lymphocytic or nodular mixed/nodular histiocytic non-Hodgkin's lymphoma, stage II--IV, were randomized to treatment with total body irradiation (TBI), 100 rads in 10 fractions over 12 days, plus combination chemotherapy with either cyclophosphamide, vincristine and prednisone...

journal_title：Cancer

authors： Brereton HD,Young RC,Longo DL,Kirkland LR,Berard CW,Jaffe ES,DeVita VT,Johnson RE

更新日期：1979-06-01 00:00:00

abstract：BACKGROUND:Glioblastoma multiforme (GBM) is the most frequent primary brain tumor in adults. Temozolomide was rapidly incorporated into first-line treatment following the publication of the pivotal European Organization for Research and Treatment of Cancer-National Cancer Institute of Canada phase 3 trial in 2005. Howe...

journal_title：Cancer

authors： Lawrence YR,Mishra MV,Werner-Wasik M,Andrews DW,Showalter TN,Glass J,Shen X,Symon Z,Dicker AP

更新日期：2012-09-01 00:00:00

abstract：:Findings from 1665 women with primary breast cancer, treated at 34 NSABP institutions in Canada and the United States, have failed to demonstrate that patients with medial-central tumors had a greater probability of developing distant metastases or dying than did those with lateral tumors despite the greater incidence...

journal_title：Cancer

authors： Fisher B,Wolmark N,Redmond C,Deutsch M,Fisher ER

更新日期：1981-10-15 00:00:00

abstract：BACKGROUND:The optimal use of radiation therapy for cancer treatment is hampered by the application of tolerance limits of normal tissues derived empirically from population averages. Such limits do not reflect the considerable differences from patient to patient in susceptibility to late radiation sequelae. Assays tha...

journal_title：Cancer

authors： Peters LJ

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:The natural history of desmoid tumors remains an enigma. Previous reports attempting to identify their biology have included recurrent and primary tumors as well as tumors from both intra- and extra-abdominal sites. The purpose of this study was to analyze patients with primary extremity and trunk desmoid tu...

journal_title：Cancer

authors： Merchant NB,Lewis JJ,Woodruff JM,Leung DH,Brennan MF

更新日期：1999-11-15 00:00:00

abstract：BACKGROUND:Desmoid tumors are mesenchymal nonmetastasizing neoplasms. Although rare in the general population, they are a common extracolonic manifestation of familial adenomatous polyposis (FAP). Because of high tumor recurrence rates, surgery has been less than satisfactory in the treatment of desmoid tumors. In the ...

journal_title：Cancer

authors： Hansmann A,Adolph C,Vogel T,Unger A,Moeslein G

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Tamoxifen and aminoglutethimide are two hormone therapies reported to be effective palliative approaches for patients with metastatic breast cancer. The current trial was designed to evaluate their relative therapeutic effectiveness. METHODS:Two hundred forty-nine postmenopausal women with advanced breast c...

journal_title：Cancer

authors： Gale KE,Andersen JW,Tormey DC,Mansour EG,Davis TE,Horton J,Wolter JM,Smith TJ,Cummings FJ

更新日期：1994-01-15 00:00:00

abstract：:Multifocal osteosarcoma with unique patho-biological features in a 23-year old white male is reported. The natural history and classification of multiple osteosarcomas are reviewed. A proposal is presented for evaluation of the multicentric origin in future cases. ...

journal_title：Cancer

authors： Mahoney JP,Spanier SS,Morris JL

更新日期：1979-11-01 00:00:00

abstract：BACKGROUND:Active surveillance (AS) with deferred treatment is an established management option for patients with prostate cancer and favorable clinical parameters. The impact of repeat biopsy after diagnosis was examined in a cohort of men with prostate cancer on AS. METHODS:In all, 186 men with prostate cancer with ...

journal_title：Cancer

authors： Al Otaibi M,Ross P,Fahmy N,Jeyaganth S,Trottier H,Sircar K,Bégin LR,Souhami L,Kassouf W,Aprikian A,Tanguay S

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:Long-term survivors of testicular cancer (TC) who received cisplatin-based chemotherapy have an increased risk of cardiovascular disease. A cross-sectional study was performed to objectively assess cardiovascular risk, subclinical atherosclerosis, and endothelial function in long-term survivors of TC. METHO...

journal_title：Cancer

authors： Vaughn DJ,Palmer SC,Carver JR,Jacobs LA,Mohler ER

更新日期：2008-05-01 00:00:00

abstract：:A case of angiosarcoma of the breast with a fatal outcome is reported, and the world literature on this rare type of breast tumor is reviewed. Familiarity with the clinical and pathologic features of this entity is essential in avoiding underdiagnosis and delay of definitive treatment. The three-year survival rate of ...

journal_title：Cancer

authors： Chen KT,Kirkegaard DD,Bocian JJ

更新日期：1980-07-15 00:00:00

abstract：:Flow cytometric measurements were done on 51 ovarian carcinoma specimens collected from consecutive patients in a prospective study. The ploidy status was related to the course of the disease. The tumors from 26 (52%) of 50 evaluable patients had DNA aneuploidy. Patients with diploid tumors were more often considered ...

journal_title：Cancer

authors： Iversen OE

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Prognostic factors for patients with stage III melanoma are still controversial. METHODS:Two hundred eighty-six patients with solitary cutaneous malignant melanoma of the skin in Stage III (International Union Against Cancer [UICC]) were followed up for as long as 11 years. RESULTS:Patients in risk group p...

journal_title：Cancer

authors： Drepper H,Biess B,Hofherr B,Hundeiker M,Lippold A,Otto F,Padberg G,Peters A,Wiebelt H

更新日期：1993-02-15 00:00:00

abstract：BACKGROUND:The objective of this study was to assess the impact of a prostate-specific antigen (PSA) complete response (PSA-CR), measured at the end of external-beam radiotherapy and short-term hormone therapy, on treatment outcomes. METHODS:The phase 3 Radiation Therapy Oncology Group 9413 trial, as part of its origi...

journal_title：Cancer

authors： Cury FL,Hunt D,Roach M 3rd,Shipley W,Gore E,Hsu IC,Krisch RE,Seider MJ,Sandler H,Lawton C

更新日期：2013-06-01 00:00:00