A comparison between combination chemotherapy and total body irradiation plus combination chemotherapy in non-Hodgkin's lymphoma.

Abstract:

:Thirty-nine untreated patients with either lymphocytic or nodular mixed/nodular histiocytic non-Hodgkin's lymphoma, stage II--IV, were randomized to treatment with total body irradiation (TBI), 100 rads in 10 fractions over 12 days, plus combination chemotherapy with either cyclophosphamide, vincristine and prednisone (CVP) or cyclophosphamide, vincristine, procarbazine and prednisone (C-MOPP) or to treatment with combination chemotherapy (CVP or C-MOPP) alone. Remission rate and duration was comparable for both treatment groups; thus the use of both treatment modalities ab initio provides no therapeutic advantage.

journal_name

Cancer

journal_title

Cancer

authors

Brereton HD,Young RC,Longo DL,Kirkland LR,Berard CW,Jaffe ES,DeVita VT,Johnson RE

doi

10.1002/1097-0142(197906)43:6<2227::aid-cncr282043

subject

Has Abstract

pub_date

1979-06-01 00:00:00

pages

2227-31

issue

6

eissn

0008-543X

issn

1097-0142

journal_volume

43

pub_type

临床试验,杂志文章,随机对照试验

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