Marjolin's ulcer. The LSU experience.

abstract：BACKGROUND:Management of unresectable colorectal liver metastases (CLM) can be by regional (hepatic arterial infusion [HAI]) or systemic chemotherapy, or by symptom control alone. In this study the costs of each type of management were related to clinical outcome in 134 patients with CLM. METHODS:The costs (both in te...

journal_title：Cancer

authors： Durand-Zaleski I,Earlam S,Fordy C,Davies M,Allen-Mersh TG

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Fas (CD95/APO-1) and Fas ligand (FasL) play key roles in immunologic homeostasis and immune privilege and may regulate normal cell turnover. Earlier studies had suggested that FasL-positive pancreatic carcinoma cell lines can induce apoptosis in T cells, thereby evading host immune surveillance. In the curre...

journal_title：Cancer

authors： Bernstorff WV,Glickman JN,Odze RD,Farraye FA,Joo HG,Goedegebuure PS,Eberlein TJ

更新日期：2002-05-15 00:00:00

abstract：BACKGROUND:Chemotherapy intensification may lead to new forms of toxicity such as hemolytic uremic syndrome. METHODS:Three patients are described who developed this complication 4 to 6 months after high dose chemotherapy followed by autologous stem cell support. The literature on this subject is reviewed. RESULTS:One...

journal_title：Cancer

authors： van der Lelie H,Baars JW,Rodenhuis S,van Dijk MA,de Glas-Vos CW,Thomas BL,van Oers RH,von dem Borne AE

更新日期：1995-12-01 00:00:00

abstract：:A growing body of research shows that a majority of patients with cancer report having religious and spiritual (R/S) beliefs, engaging in R/S behaviors, or deriving comfort from R/S experiences. These studies have been reviewed but not subjected to rigorous critical analysis. A meta-analytic approach is needed to prov...

journal_title：Cancer

authors： Salsman JM,Fitchett G,Merluzzi TV,Sherman AC,Park CL

更新日期：2015-11-01 00:00:00

abstract：:The acquisition of ligand-independent ESR1 mutations during aromatase inhibitor therapy in metastatic estrogen receptor (ER)-positive breast cancer is a common mechanism of hormonal therapy resistance. Preclinical and clinical studies have demonstrated that ESR1 mutations can preexist in primary tumors and can be enri...

journal_title：Cancer

authors： Dustin D,Gu G,Fuqua SAW

更新日期：2019-11-01 00:00:00

abstract：BACKGROUND:Plasma acidic glutathione S-transferase (GST-pi) concentrations in 135 patients with gastrointestinal cancer were measured by an improved radioimmunoassay (RIA). METHODS:Blood was collected into a silicified glass tube containing a specific anticoagulant. The plasma, which was separated rapidly by centrifug...

journal_title：Cancer

authors： Fan KC,Huang YC,Li CH

更新日期：1995-10-15 00:00:00

abstract：BACKGROUND:Melanoma is the most lethal form of skin cancer, with an estimated 68,130 new cases and 8700 deaths in the United States in 2010. The increasing incidence and high death rate associated with metastatic disease support the need to focus on prevention. The authors used data from the Women's Health Initiative (...

journal_title：Cancer

authors： Jagtap D,Rosenberg CA,Martin LW,Pettinger M,Khandekar J,Lane D,Ockene I,Simon MS

更新日期：2012-10-15 00:00:00

abstract：:Forty-two cases of sarcomatoid renal cell carcinoma were reviewed clinicopathologically. Twenty-four patients were men, and 18 women; average age was 56.2 years (range, 30-81 years). Eight, 9, 13, and 12 cases were Stages I, II, III, and IV, respectively. Three morphologic patterns of sarcomatoid components were ident...

journal_title：Cancer

authors： Ro JY,Ayala AG,Sella A,Samuels ML,Swanson DA

更新日期：1987-02-01 00:00:00

abstract：:As the federal government struggles to meet ever-growing budgetary constraints, the need for research into the causes of and potential therapies for treating cancer demands the urgent attention of Congressional leaders. This will require innovative, cost-effective approaches to address the unique needs of cancer resea...

journal_title：Cancer

authors： Mack C

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The optimal use of radiation therapy for cancer treatment is hampered by the application of tolerance limits of normal tissues derived empirically from population averages. Such limits do not reflect the considerable differences from patient to patient in susceptibility to late radiation sequelae. Assays tha...

journal_title：Cancer

authors： Peters LJ

更新日期：1996-06-01 00:00:00

abstract：:A prospective study was performed on 84 patients with neuroendocrine pancreatic tumors. Fifty-nine (70%) had malignant tumors and received causal medical treatment. Streptozotocin in combination with 5-fluorouracil or doxorubicin was used as first-line treatment and produced overall objective responses in 20 of 44 (45...

journal_title：Cancer

authors： Eriksson B,Skogseid B,Lundqvist G,Wide L,Wilander E,Oberg K

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:This Phase III trial was performed to compare the roles of oral etoposide and intravenous (i.v.) vinblastine in the treatment of Mediterranean Kaposi's Sarcoma (MEKS) in elderly patients with severe disease (Stages II, Ac/B, III, and IV). PATIENTS AND METHODS:Sixty-five patients were randomized to receive e...

journal_title：Cancer

authors： Brambilla L,Labianca R,Boneschi V,Fossati S,Dallavalle G,Finzi AF,Luporini G

更新日期：1994-11-15 00:00:00

abstract：:Three cases of pulmonary lymphangiomyomatosis are described, with emphasis on the ultrastructural changes. The clinicopathologic features corresponded to those previously described. Each patient was a female in the reproductive years; breathlessness and recurrent pneumothoraces were the predominant clinical features. ...

journal_title：Cancer

authors： Basset F,Soler P,Marsac J,Corrin B

更新日期：1976-12-01 00:00:00

abstract：:Renal cell carcinoma (RCC) evokes an immune response, which occasionally has resulted in spontaneous and dramatic remissions. In an attempt to reproduce or accentuate this response, various immunotherapeutic strategies have been studied. The most consistent antitumor activity has been reported with interferon-alpha (I...

journal_title：Cancer

authors： McDermott DF

更新日期：2009-05-15 00:00:00

abstract：BACKGROUND:Chemotherapy improves survival for patients with stage III colon cancer, but some older patients with lymph node-positive colon cancer do not see a medical oncologist and, thus, do not receive adjuvant chemotherapy. METHODS:To evaluate the role of the surgeon in determining referrals to medical oncology amo...

journal_title：Cancer

authors： Luo R,Giordano SH,Zhang DD,Freeman J,Goodwin JS

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND:Preclinical and clinical studies suggest synergistic activity between somatostatin analogues and mammalian target of rapamycin inhibitors. The activity and safety of everolimus was assessed in combination with octreotide long-acting repeatable (LAR) in patients with neuroendocrine tumors (NETs) of gastroente...

journal_title：Cancer

authors： Bajetta E,Catena L,Fazio N,Pusceddu S,Biondani P,Blanco G,Ricci S,Aieta M,Pucci F,Valente M,Bianco N,Mauri CM,Spada F

更新日期：2014-08-15 00:00:00

abstract：BACKGROUND:Several of the large studies addressing prognosis and survival from hepatocellular carcinoma (HCC) have been from Europe and Asia, but only a few have emanated from North America. Survival statistics from other parts of the world may not be applicable to the North American population because of etiologic, de...

journal_title：Cancer

authors： Nzeako UC,Goodman ZD,Ishak KG

更新日期：1995-08-15 00:00:00

abstract：BACKGROUND:Lymphedema of the arm is a serious consequence of breast carcinoma treatment. Postmastectomy lymphedema of the upper limb usually is related to certain risk factors such as axillary surgery, radiotherapy, obesity, venous outflow obstruction, delayed wound healing, and infection. The objective of the current ...

journal_title：Cancer

authors： Herd-Smith A,Russo A,Muraca MG,Del Turco MR,Cardona G

更新日期：2001-10-01 00:00:00

abstract：:Breast cancer tissue from 12 male patients was evaluated for the presence of estrogen receptors (ER), and at least 10 of 12 were found to be high in ER (ER+). A combination of previously published cases and our own experience indicates that 80% of patients (37/47) have ER+ tumors. This incidence of ER positivity in me...

journal_title：Cancer

authors： Friedman MA,Hoffman PG Jr,Dandolos EM,Lagios MD,Johnston WH,Siiteri PK

更新日期：1981-01-01 00:00:00

abstract：:Malignant fibrous histiocytoma of soft tissues (MFH), a mesenchymal tumor of varied morphologic patterns and cell types, sometimes contains bone and cartilage. Such bony and cartilaginous elements in a pleomorphic MFH may pose a difficult diagnostic challenge. An MFH with bone and cartilage can be distinguished from e...

journal_title：Cancer

authors： Bhagavan BS,Dorfman HD

更新日期：1982-02-01 00:00:00

abstract：BACKGROUND:: The purpose of this study was to evaluate the impact of postmastectomy breast reconstruction on the timing of chemotherapy. METHODS:: The authors included stage I-III breast cancer patients from 8 National Comprehensive Cancer Network institutions for whom guidelines recommended chemotherapy. Surgery type...

journal_title：Cancer

authors： Alderman AK,Collins ED,Schott A,Hughes ME,Ottesen RA,Theriault RL,Wong YN,Weeks JC,Niland JC,Edge SB

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:Irinotecan-based chemotherapy regimens are 1 option for treatment of metastatic colorectal cancer (mCRC). The authors report the safety and efficacy of such regimens in elderly patients using a large phase III trial (bolus, infusional, or capecitabine with camptostar-celecoxib [BICC-C]) cohort. METHODS:In p...

journal_title：Cancer

authors： Jackson NA,Barrueco J,Soufi-Mahjoubi R,Marshall J,Mitchell E,Zhang X,Meyerhardt J

更新日期：2009-06-15 00:00:00

abstract：:Currently, there is a "divide" between cancer survivorship initiatives and minority participation. The level of participation is nearly nonexistent in many cancer support and control initiatives. Cancer survivorship resources that facilitate access to treatment, psychosocial interventions, clinical trials, and researc...

journal_title：Cancer

authors： Guidry JJ,Torrence W,Herbelin S

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Proliferating cell nuclear antigen (PCNA) is an intranuclear protein that is linked closely to the cell cycle. An immunohistochemical study was performed on the expression of PCNA in various sized hepatocellular carcinomas (HCCs) to determine the relation between the proliferative activity of cancer cells an...

journal_title：Cancer

authors： Suehiro T,Matsumata T,Itasaka H,Yamamoto K,Kawahara N,Sugimachi K

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:Radiologic Diagnostic Oncology Group 5 is a multicenter clinical trial designed to evaluate fine-needle aspiration (FNA) of nonpalpable breast lesions performed by multiple operators using the same protocol. METHODS:Four hundred and nineteen women with mammographically detected nonpalpable breast lesions we...

journal_title：Cancer

authors： Pisano ED,Fajardo LL,Tsimikas J,Sneige N,Frable WJ,Gatsonis CA,Evans WP,Tocino I,McNeil BJ

更新日期：1998-02-15 00:00:00

abstract：BACKGROUND:The objective of this Phase II study was to evaluate the concept of sequential chemotherapy in the treatment of patients with advanced nonsmall cell lung carcinoma (NSCLC) by the administration of carboplatin plus gemcitabine followed by of paclitaxel. METHODS:Patients with Stage IIIB (pleural effusion) or ...

journal_title：Cancer

authors： Edelman MJ,Gandara DR,Lau DH,Lara P,Lauder IJ,Tracy D

更新日期：2001-07-01 00:00:00

abstract：:The development of resistance to purine analogs defines a poor-risk subset of patients with chronic lymphocytic leukemia (CLL). Although in recent years chemoimmunotherapeutic combinations such as fludarabine, cyclophosphamide, and rituximab have induced response rates of 95% in previously untreated patients and incre...

journal_title：Cancer

authors： Tsimberidou AM,Keating MJ

更新日期：2009-07-01 00:00:00

abstract：:This report describes a case of null cell congenital acute lymphoblastic leukemia associated with a (4;11) translocation. This chromosome abnormality is associated with acute lymphoblastic leukemia and probably more specifically with congenital acute lymphoblastic leukemia. A review of the literature is presented. ...

journal_title：Cancer

authors： Esseltine DW,Vekemans M,Seemayer T,Reece E,Gordon J,Whitehead VM

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND:The Women's Health Initiative randomized clinical trial reported that menopausal hormone therapy increases lung cancer mortality risk. If this is true, use of anti-estrogens should be associated with decreased lung cancer mortality risk. The authors compared lung cancer incidence and mortality among breast c...

journal_title：Cancer

authors： Bouchardy C,Benhamou S,Schaffar R,Verkooijen HM,Fioretta G,Schubert H,Vinh-Hung V,Soria JC,Vlastos G,Rapiti E

更新日期：2011-03-15 00:00:00

abstract：BACKGROUND:Cancer costs should be discussed by patients and providers, but information is not readily available. Results from recently published studies (in the last 5 years) on direct and indirect cancer costs may help guide these discussions. METHODS:The authors reviewed studies published between 2013 and 2017 that ...

journal_title：Cancer

authors： Pisu M,Henrikson NB,Banegas MP,Yabroff KR

更新日期：2018-11-01 00:00:00