Response to second-line hormone treatment for advanced breast cancer. Predictive value of ploidy determination.

abstract：BACKGROUND:A higher total dose of radiation therapy administered in fractionated lower individual doses twice daily (hyperfractionated radiation therapy) has been reported to improve survival for children with brain stem gliomas. However, this higher dose of radiation therapy may cause more sequelae. METHOD:Eighty-eig...

journal_title：Cancer

authors： Packer RJ,Zimmerman RA,Kaplan A,Wara WM,Rorke LB,Selch M,Goldwein J,Allen JA,Boyett J,Albright AL

更新日期：1993-04-15 00:00:00

abstract：:Lymphocytic and plasmocytic infiltration surrounding a malignant tumor probably represents an immunologic response of the host directed against the neoplasm. It has been documented that lymphocytic infiltration has a favorable effect on prognosis in a number of human tumor systems, including cutaneous melanoma. In the...

journal_title：Cancer

authors： Lang JR,Davidorf FH,Baba N

更新日期：1977-11-01 00:00:00

abstract：:In estrogen target tissues and hormone-dependent tumors, the steroid enters the cells and binds to a cytoplasmic protein called the estrogen receptor (ER). The steroid-receptor complex then migrates to the nuclei, where it initiates the biochemicial events characteristic of estrogen stimulation. Since ER is absent in ...

journal_title：Cancer

authors： McGuire WL

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:Poor accrual to cancer clinical trials may contribute to the lower improvement in survival observed for adolescents and young adults (AYAs) (those aged 15-39 years) with cancer. This has been difficult to quantify without reliable mechanisms to link incident cases with study enrollments. Using unique resourc...

journal_title：Cancer

authors： Collins CL,Malvar J,Hamilton AS,Deapen DM,Freyer DR

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:: Delirium has been the most frequent neuropsychiatric complication in patients with advanced cancer. This exploratory study aimed to determine the proportion of patients who were able to recall their experience of delirium and the level of distress experienced by patients, family caregivers, and healthcare ...

journal_title：Cancer

authors： Bruera E,Bush SH,Willey J,Paraskevopoulos T,Li Z,Palmer JL,Cohen MZ,Sivesind D,Elsayem A

更新日期：2009-05-01 00:00:00

abstract：:One hundred thirty-nine consecutive unselected adults with acute nonlymphoblastic leukemia were treated with a high-dose chemotherapeutic remission-induction regimen consisting of daunomycin (70 mg/m2 IV on days 1, 2, 3), cytosine arabinoside (100 mg/m2 IV every 12 hours), 6-thioguanine (100 mg/m2 orally every 12 hour...

journal_title：Cancer

authors： Glucksberg H,Cheever MA,Farewell VT,Fefer A,Sale GE,Thomas ED

更新日期：1981-09-01 00:00:00

abstract：:The authors draw on the lessons highlighted in preceding articles in the current supplement to provide recommendations for cancer screening intervention research and to highlight some of the many questions that will require further investigation. ...

journal_title：Cancer

authors： Meissner HI,Vernon SW,Rimer BK,Wilson KM,Rakowski W,Briss PA,Smith RA

更新日期：2004-09-01 00:00:00

abstract：BACKGROUND:Current clinical guidelines recommend earlier, more intensive breast cancer screening with both magnetic resonance imaging (MRI) and mammography for women with breast cancer susceptibility gene (BRCA) mutations. Unspecified details of screening schedules are a challenge for implementing guidelines. METHODS:...

journal_title：Cancer

authors： Cott Chubiz JE,Lee JM,Gilmore ME,Kong CY,Lowry KP,Halpern EF,McMahon PM,Ryan PD,Gazelle GS

更新日期：2013-03-15 00:00:00

abstract：BACKGROUND:In spite of many reports, it remains unclear whether the presence of tumor cells in circulating blood flow predicts a poor prognosis. METHODS:Competitive seminested reverse transcriptase-polymerase chain reaction (RT-PCR), a technique for the quantitative detection of tumor cells, was applied to detect the ...

journal_title：Cancer

authors： Sadahiro S,Suzuki T,Tokunaga N,Yurimoto S,Yasuda S,Tajima T,Makuuchi H,Murayama C,Matsuda K

更新日期：2001-09-01 00:00:00

abstract：:The authors studied the expression of c-myc and ras family oncogene products in 43 cases of malignant lymphoma (ML) using the immunoperoxidase method. Unfixed frozen sections of lymph nodes from four patients with Hodgkin's disease and 39 with non-Hodgkin's lymphoma, together with normal lymph nodes, were studied by t...

journal_title：Cancer

authors： Mitani S,Sugawara I,Shiku H,Mori S

更新日期：1988-11-15 00:00:00

abstract：BACKGROUND:A phase II prospective trial was carried out to study the concept of 5-fluorouracil (5-FU) dose-intensity in patients with advanced colorectal cancer. Forty patients were treated with 5-FU plus leucovorin (LV), with individually increasing doses of 5-FU. A 5-FU pharmacokinetic follow up was performed and a r...

journal_title：Cancer

authors： Gamelin EC,Danquechin-Dorval EM,Dumesnil YF,Maillart PJ,Goudier MJ,Burtin PC,Delva RG,Lortholary AH,Gesta PH,Larra FG

更新日期：1996-02-01 00:00:00

abstract：:The clinical and pathologic features of eight infants with monocytic leukemia are reviewed. The children were all aged 12 months or less at diagnosis and had a high incidence of extramedullary features, skin infiltration being particularly common. The diagnosis was established by conventional morphologic and cytochemi...

journal_title：Cancer

authors： Darbyshire PJ,Smith JH,Oakhill A,Mott MG

更新日期：1985-10-01 00:00:00

abstract：:Prognostic factors were evaluated in 109 soft tissue sarcomas of the extremities, walls of the trunk, head, and neck. All lesions were graded according to the systems proposed by the National Cancer Institute (NCI) and the French Federation of Cancer Centers (FNCLCC), and a correlation was found between tumor grade an...

journal_title：Cancer

authors： Mandard AM,Petiot JF,Marnay J,Mandard JC,Chasle J,de Ranieri E,Dupin P,Herlin P,de Ranieri J,Tanguy A

更新日期：1989-04-01 00:00:00

abstract：:The discovery that the human papilloma virus (HPV) is associated with a high and increasing percentage of oropharyngeal squamous cell carcinomas (SCCs) is among the most significant advances in the field of head and neck oncology. HPV-positive oropharyngeal cancer (HPVOPC) has clinical, etiologic, pathologic, and mole...

journal_title：Cancer

authors： Urban D,Corry J,Rischin D

更新日期：2014-05-15 00:00:00

abstract：:Amputation is often a component in the treatment of bone tumors such as osteogenic sarcoma, which is most prevalent in the adolescent age group. Adaptation to cancer and loss of a limb requires a significant multidimensional effort. To examine the role of social support systems, 27 adolescents who had undergone amputa...

journal_title：Cancer

authors： Tebbi CK,Stern M,Boyle M,Mettlin CJ,Mindell ER

更新日期：1985-08-15 00:00:00

abstract：BACKGROUND:A considerable body of evidence supports the concept that a significant number of cutaneous malignant melanomas progress through a precursor lesion or dysplastic melanocytic nevi (DN). Tumor angiogenesis likely plays a critical role in early development of melanoma, and intermediate biomarkers of angiogenesi...

journal_title：Cancer

authors： Einspahr JG,Thomas TL,Saboda K,Nickolof BJ,Warneke J,Curiel-Lewandrowski C,Ranger-Moore J,Duckett L,Bangert J,Fruehauf JP,Alberts DS

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:This qualitative study investigated the medical decision-making preferences of adolescent oncology patients and the parental and clinician behaviors that adolescents report to be supportive of their preferred level of decision-making involvement. METHODS:Interviews were conducted with 40 adolescents between...

journal_title：Cancer

authors： Weaver MS,Baker JN,Gattuso JS,Gibson DV,Sykes AD,Hinds PS

更新日期：2015-12-15 00:00:00

abstract：:During the period 1955 to 1975, 63 consecutive cases of apical lung carcinoma were treated in the Radiation Therapy Division of the University of Michigan Medical Center (UMMC). Supervoltage external radiation alone or combination of radiation and surgery were the main modalities of treatment used in these patients. O...

journal_title：Cancer

authors： Ahmad K,Fayos JV,Kirsh MM

更新日期：1984-09-01 00:00:00

abstract：:A study of 112 biopsy specimens from Danish oral leukoplakia patients and 145 biopsy specimens from Indian leukoplakia patients revealed a chevron-like keratinization of the epithelium in a number of cases. Clinically, this type of keratinization was often characterized by a pumice-like appearance. The clinical and hi...

journal_title：Cancer

authors： Pindborg JJ,Reibel J,Roed-Peterson B,Mehta FS

更新日期：1980-05-01 00:00:00

abstract：:A 17 year old man with a primary intracranial germ cell tumor in the pituitary region is reported. Both serum alpha-fetoprotein (AFP) and serum human chorionic gonadotropin (hCG) were found elevated preoperatively. Normal levels of serum AFP and hCG were found after operation and radiotherapy. By indirect immunofluore...

journal_title：Cancer

authors： Nørgaard-Pedersen B,Lindholm J,Albrechtsen R,Arends J,Diemer NH,Riishede J

更新日期：1978-06-01 00:00:00

abstract：:High tissue concentrations of human chorionic gonadotropin (hCG) and alpha-fetoprotein (AFP) were revealed by radioimmunoassay in a hepatic tumor which was surgically removed from a two-year, eight-month-old boy manifesting sexual precocity. Histologically the tumor showed an embryonal type hepatoblastoma admixed with...

journal_title：Cancer

authors： Morinaga S,Yamaguchi M,Watanabe I,Kasai M,Ojima M,Sasano N

更新日期：1983-05-01 00:00:00

abstract：:A total of 289 cases with malignant pleuroperitoneal effusions were reviewed, and their prognosis were analyzed in relation to the following factors: (1) chronologically divided series; (2) previous tumorectomy of the primary lesion; (3) presence or absence of other metastases; (4) site of effusion; (5) site of the pr...

journal_title：Cancer

authors： Yamada S,Takeda T,Matsumoto K

更新日期：1983-01-01 00:00:00

abstract：BACKGROUND:The current study was designed to evaluate the efficacy and toxicity of the continuous oral administration of a combination of cyclophosphamide (50 mg/day given in the morning) and dexamethasone (1 mg/day given in the evening) in patients with prostate specific antigen (PSA) progression despite single or mul...

journal_title：Cancer

authors： Glode LM,Barqawi A,Crighton F,Crawford ED,Kerbel R

更新日期：2003-10-15 00:00:00

abstract：:The effect of cyclophosphamide (CY) on ovarian function was studied in patients with breast cancer receiving prolonged daily administration of this agent (100 mg/day) after radical surgery. Out of 18 premenopausal patients that received 8.4-39.9 g CY, 15 developed permanent amenorrhea. The average dose given before th...

journal_title：Cancer

authors： Koyama H,Wada T,Nishizawa Y,Iwanaga T,Aoki Y

更新日期：1977-04-01 00:00:00

abstract：:In a cohort of 254,417 male Swedish farmers (4,330,717 person-years) the incidence of cancer of the respiratory organs was compared to a reference cohort of 1,725,845 men (30,131,664 person-years) employed in other economic activities than agriculture or forestry. In the study cohort 1450 cases of cancer in the respir...

journal_title：Cancer

authors： Wiklund K,Steineck G

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Micropapillary serous carcinoma (MPSC), a recently described entity, is an ovarian tumor with a distinctive histologic architecture that lacks a destructive infiltrative growth pattern and behaves like a low-grade neoplasm. The purpose of this study was to determine if specific cytomorphologic features were ...

journal_title：Cancer

authors： Alli PM,Ali SZ

更新日期：2002-06-25 00:00:00

abstract：BACKGROUND:Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is the only treatment with a curative potential for myelodysplastic syndrome (MDS) patients. Allo-HSCT has substantial risks, particularly in the elderly, and its role for older MDS patients has yet to be defined. METHODS:We analyzed 88 MDS pati...

journal_title：Cancer

authors： Yucel OK,Saliba RM,Rondon G,Ahmed S,Alousi A,Bashir Q,Ciurea SO,Popat U,Khouri I,Marin D,Rezvani K,Kebriaei P,Shpall EJ,Champlin RE,Oran B

更新日期：2017-07-15 00:00:00

abstract：BACKGROUND:It has been previously observed that patients with head and neck squamous cell carcinoma or with laryngeal leucoplakia present a significant reduction in plasma folate levels. The current Phase IIA pilot study assessed the effectiveness of folic acid as a chemopreventive agent in patients affected by glottic...

journal_title：Cancer

authors： Almadori G,Bussu F,Navarra P,Galli J,Paludetti G,Giardina B,Maurizi M

更新日期：2006-07-15 00:00:00

abstract：BACKGROUND:African-American (AA) women have lower survival rates from cervical cancer compared with white women. The objective of this study was to examine the influence of socioeconomic status (SES) and other variables on racial disparities in overall survival among women with invasive cervical cancer. METHODS:One th...

journal_title：Cancer

authors： Movva S,Noone AM,Banerjee M,Patel DA,Schwartz K,Yee CL,Simon MS

更新日期：2008-03-15 00:00:00

abstract：:Ninety-four patients with lymphoma involving the extradural space with spinal cord compression proven at the time of laminectomy were reviewed. There were about three times as many patients with non-Hodgkin's lymphoma than with Hodgkin's disease. The majority of those with Hodgkin's disease had a proven histologic dia...

journal_title：Cancer

authors： Haddad P,Thaell JF,Kiely JM,Harrison EG,Miller RH

更新日期：1976-10-01 00:00:00