Abstract:
:Ninety-four patients with lymphoma involving the extradural space with spinal cord compression proven at the time of laminectomy were reviewed. There were about three times as many patients with non-Hodgkin's lymphoma than with Hodgkin's disease. The majority of those with Hodgkin's disease had a proven histologic diagnosis before the onset of the spinal cord compression syndrome, whereas only 15% of those with non-Hodgkin's lymphoma had previously been so diagnosed. Plain roentgenograms of the spine were suggestive of tumor involvement in less than one-third of the patients, whereas myelograms were invariably abnormal. As noted by others, the outlook for functional recovery and extended life expectancy is relatively good for patients with this type of cancer, in contrast to reports in the literature regarding prognosis for patients who have metastatic carcinoma with extradural spinal cord compression.
journal_name
Cancerjournal_title
Cancerauthors
Haddad P,Thaell JF,Kiely JM,Harrison EG,Miller RHdoi
10.1002/1097-0142(197610)38:4<1862::aid-cncr282038subject
Has Abstractpub_date
1976-10-01 00:00:00pages
1862-6issue
4eissn
0008-543Xissn
1097-0142journal_volume
38pub_type
杂志文章相关文献
CANCER文献大全abstract:BACKGROUND:Serum alpha-L-fucosidase activity is considered a marker of hepatocellular carcinoma. To the authors' knowledge, its clinical usefulness in the early detection of hepatocellular carcinoma in the follow-up of cirrhotic patients has not been reported previously. METHODS:The authors prospectively studied serum...
journal_title:Cancer
pub_type: 杂志文章
doi:
更新日期:1998-12-15 00:00:00
abstract:BACKGROUND:: Invasive aspergillosis (IA) is a common complication in patients with hematologic malignancies. Patients with solid tumors also are at risk for IA because they may develop neutropenia as a result of chemotherapy and radiotherapy. However, studies of IA in patients with solid tumors are rare. In this study,...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.24559
更新日期:2009-11-01 00:00:00
abstract::Three screening programs for early cervical cancer currently in use in Japan were evaluated according to the following criteria: (1) economic effectiveness; (2) screening efficiency; and (3) access to medical care. The mobile program has the highest benefit-cost ratio (BCR, 1.20) and is hence most cost-effective; its ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19850515)55:10<2514::aid-cncr282
更新日期:1985-05-15 00:00:00
abstract::A prospective study was carried out on 22 patients to assess the diagnostic ability to stage renal cell carcinoma by computed tomography, dynamic computed tomography, arteriography, ultrasonography, and radionuclide scanning. Dynamic computed tomography remedied the most consequential diagnostic shortcomings of conven...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19841115)54:10<2205::aid-cncr282
更新日期:1984-11-15 00:00:00
abstract::The authors reviewed clinical features, surgical extent of resection, histologic parameters, and DNA content in 55 children with medulloblastomas and found that complete or near total resection, absence of tumor dissemination, tumor DNA aneuploidy, and low proliferative index correlated with a favorable clinical outco...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.2820690539
更新日期:1992-03-01 00:00:00
abstract:BACKGROUND:Sacituzumab govitecan (IMMU-132), an antitrophoblastic cell-surface antigen (anti-Trop-2) humanized antibody-SN-38 conjugate, had encouraging efficacy in the phase 1 clinical trial. This report further examines the pharmacokinetics and safety of multiple cycles of IMMU-132 at doses of 8 or 10 mg/kg in patien...
journal_title:Cancer
pub_type: 杂志文章,多中心研究
doi:10.1002/cncr.30789
更新日期:2017-10-01 00:00:00
abstract:BACKGROUND:This study was conducted to evaluate whether estramustine (estrogen mustard [EM]) is a promising alternative in the treatment of patients with epithelial ovarian carcinoma (OVCA). EM is a microtubule-associated protein (MAP) specific antimicrotubule agent with low toxicity. METHODS:The authors investigated ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(sici)1097-0142(19990615)85:12<2616::aid-c
更新日期:1999-06-15 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) with portal venous invasion (PVI) has a very poor prognosis, with a median survival of 3 months and virtually no survival at 1 year. The combination of intraarterial 5-fluorouracil (FU) and systemic interferon-alpha (IFNalpha) was recently reported to be effective against HCC w...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.21832
更新日期:2006-05-01 00:00:00
abstract::Neuroblastoma is the most common neoplasm in children less than 1 year of age and has one of the earliest incidence peaks of all childhood cancers. Using birth registration data, a matched case-control study was undertaken to investigate potential prenatal and perinatal risk factors. Ninety-seven neuroblastoma patient...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19880601)61:11<2202::aid-cncr282
更新日期:1988-06-01 00:00:00
abstract::Epidemiologic and laboratory data suggest that cervical cancer typically arises from a series of causal steps. Each step can be studied separately in the hope of better etiologic understanding and improved cancer prevention. The earliest identified etiologic step is infection of young women with specific types of vene...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/1097-0142(19951115)76:10+<1888::aid-cncr28
更新日期:1995-11-15 00:00:00
abstract:BACKGROUND:Nodal status is one of the most important prognostic factors for distal bile duct cancer. The pattern of lymphatic spread of distal bile duct cancer was analyzed by determining the frequency of involvement of various lymph nodes. MATERIALS AND METHODS:From 1973 to 1991, 29 patients with distal bile duct can...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19931001)72:7<2112::aid-cncr2820
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND:A crossover in breast carcinoma incidence at ages 45-49 years has been observed between black and white women, with blacks experiencing higher incidence at younger ages and lower incidence after age 50 years. Can this phenomenon be partially explained by the differences in the distributions of reproductive r...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/(sici)1097-0142(20000301)88:5+<1230::aid-c
更新日期:2000-03-01 00:00:00
abstract:BACKGROUND:Febrile neutropenia (FN) is a serious and potentially life-threatening condition that may develop in patients with cancer who receive myelosuppressive chemotherapy. The risk of mortality from FN is not well characterized in current clinical practice. METHODS:Patients with cancer who were receiving chemother...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.25332
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Polyunsaturated n-3 fatty acids have been shown to inhibit the growth and metastasis of tumors. This double-blind, randomized study was designed to evaluate the hypothesis that polyunsaturated n-3 fatty acids can improve metabolic parameters, decrease chemical indices of inflammation, enhance quality of life...
journal_title:Cancer
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2000-04-15 00:00:00
abstract::Fiberoptic endoscopic examination and biopsy of the nasopharynx was done in 130 patients as a prospective study. They all had elevated titers of antibodies against the viral capsid antigen of Epstein-Barr virus but no symptoms or signs of nasopharyngeal carcinoma. Each underwent a biopsy from six fixed sites in the na...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19910615)67:12<3127::aid-cncr282
更新日期:1991-06-15 00:00:00
abstract::Age-specific incidence curves, cumulative rates, and relative risks were estimated for selected malignancies among male veterans utilizing the Veterans Administration (VA) medical system during 1970 to 1982. Relative risks for malignant tumors of the lung, bronchus, larynx, oral cavity, and esophagus in males using VA...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19890901)64:5<1160::aid-cncr2820
更新日期:1989-09-01 00:00:00
abstract::Formal cancer survivorship care is a growing focus internationally. This article provides a broad overview of the national strategies currently in progress for the development of survivorship programs and care plans within the United States and across Europe. The different approaches taken in their implementation, sta...
journal_title:Cancer
pub_type: 杂志文章,评审
doi:10.1002/cncr.28068
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:The objective of this article was to assess the clinimetric properties of the International Federation of Gynecology and Obstetrics (FIGO) staging system of cervical carcinoma to determine whether it is an adequate prognostic tool for the survival of patients with cervical carcinoma. METHODS:The FIGO stagin...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(20010815)92:4<796::aid-cncr1385>
更新日期:2001-08-15 00:00:00
abstract:BACKGROUND:The observed seasonal and geographic variations in the incidence of immunoproliferative small intestinal disease (IPSID) suggest that environmental factors contribute to its pathogenesis. One such environmental factor, the Epstein-Barr virus (EBV), has been associated with other B-cell lymphoproliferative di...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19940915)74:6<1699::aid-cncr2820
更新日期:1994-09-15 00:00:00
abstract:BACKGROUND:The mortality rate associated with fever accompanied by pulmonary infiltrates after chemotherapy for hematologic malignancies remains higher than the corresponding rate associated with febrile neutropenia without pulmonary infiltrates. Nonetheless, few studies have focused on the factors that predict outcome...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.20406
更新日期:2004-08-01 00:00:00
abstract:BACKGROUND:Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS:By using population-based registry linkage information from the US Transpla...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.31359
更新日期:2018-06-15 00:00:00
abstract:BACKGROUND:It remains unclear whether primary tumor resection benefits patients with metastatic neuroblastoma. The authors assessed the impact of extent and timing of resection on outcome in these patients. METHODS:The authors reviewed the records of 124 patients > 1 year of age at diagnosis of International Neuroblas...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21566
更新日期:2005-12-15 00:00:00
abstract::The expression of the Thomsen-Friedenreich antigen (T-antigen) in normal and neoplastic urothelium was investigated using paraffin-processed and fresh frozen tissue sections obtained by biopsy from 56 patients. The T-antigen was detected through its binding to the peanut agglutinin (PNA) with two methods: a biotin-avi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(19860915)58:6<1236::aid-cncr2820
更新日期:1986-09-15 00:00:00
abstract:BACKGROUND:In this prospective study, the authors evaluated potential treatment toxicity and progression-free survival in patients with low-grade glioma who received treatment with proton radiation therapy. METHODS:Twenty patients with World Health Organization grade 2 glioma who were eligible for radiation therapy we...
journal_title:Cancer
pub_type: 临床试验,杂志文章
doi:10.1002/cncr.29237
更新日期:2015-05-15 00:00:00
abstract:BACKGROUND:The authors analyzed the outcomes of patients treated with radiotherapy (RT) alone or combined with surgery for carcinoma of the salivary glands. METHODS:Between October 1964 and June 2003, 224 previously untreated patients were treated with curative intent with RT alone (n = 64) or combined with surgery (n...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.21083
更新日期:2005-06-15 00:00:00
abstract:BACKGROUND:Meeting quality of care standards in oncology is recognized as important by physicians, professional organizations, and payers. Data from a population-based cohort of patients with prostate cancer were used to examine whether receipt of care was consistent with published consensus metrics and whether receivi...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.30315
更新日期:2017-01-01 00:00:00
abstract:BACKGROUND:Historically, estrogen receptor (ER) determinations have been made by the ligand-binding assay of tumor homogenates, primarily by the dextran-coated charcoal method (DCC). Immunocytochemical assays (ICA) for ER are more recent and have been executed mostly on frozen sections with the monoclonal antibody H222...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/(SICI)1097-0142(19960615)77:12<2514::AID-C
更新日期:1996-06-15 00:00:00
abstract:BACKGROUND:Despite advances in first-line therapy, there are few data on treatment of glioblastoma multiforme (GBM) at recurrence. Temozolomide (TMZ) is well tolerated and may have activity despite prior TMZ exposure if novel dose schedules are used. METHODS:The authors reviewed their experience with a continuous TMZ ...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.23813
更新日期:2008-10-15 00:00:00
abstract:BACKGROUND:PC-SPES is an herbal supplement whose mechanisms of action are poorly understood, but may be estrogenic. The objective of the current report is to describe the effects of discontinuing PC-SPES treatment in four patients with androgen-independent prostate carcinoma. METHODS:Patient charts were retrospectivel...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/cncr.10269
更新日期:2002-02-01 00:00:00
abstract::The clinicopathologic significance of mucus production by adenocarcinoma of the colon and rectum was analyzed in retrospective study with stage matched non-mucus producing control carcinomas. Mucinous carcinoma of the colon and rectum comprised 132 (15%) of 893 cases of colorectal carcinoma. The rectum was the most co...
journal_title:Cancer
pub_type: 杂志文章
doi:10.1002/1097-0142(197604)37:4<1891::aid-cncr282037
更新日期:1976-04-01 00:00:00