Ultrastructural characteristics of therapy-related acute nonlymphocytic leukemia: evidence for a panmyelosis.

abstract：BACKGROUND:Current techniques to define gastric neoplasia are limited but molecular genetic signatures can categorize tumors and provide biological rationale for predicting clinical behavior. We identified three gene signatures: Chromogranin A (CgA), MAGE-D2 (adhesion), and MTA1 (metastasis) that define gastrointestina...

journal_title：Cancer

authors： Kidd M,Modlin IM,Mane SM,Camp RL,Eick GN,Latich I,Zikusoka MN

更新日期：2006-04-01 00:00:00

abstract：:The establishment and characterization of 11 human lung cancer cell lines are described in this article. Nine of these cell lines were established over a 5-year period, from 1983 to 1988, from patients treated at the Kingston Regional Cancer Centre. These include eight definite or probable small cell lung cancer (SCLC...

journal_title：Cancer

authors： Campling BG,Haworth AC,Baker HM,Greer DL,Holden JJ,Bradley EC,Pym J,Dexter DF

更新日期：1992-04-15 00:00:00

abstract：:The present overview of advanced prostate cancer required the identification of randomized clinical trials studying the question of maximal androgen blockade versus the classic castration therapy. The heterogeneity of the trials concerned the type of castration (surgical or chemical) and the type of antiandrogen (flut...

journal_title：Cancer

authors： Suciu S,Sylvester R,Iversen P,Christensen I,Denis L

更新日期：1993-12-15 00:00:00

abstract：BACKGROUND:Previous data from the National Cancer Data Base have examined time trends in stage of disease, treatment patterns, and survival for selected cancers. The most current (1993) data for breast carcinoma are described here. METHODS:Five Calls for Data have yielded a total of 508,724 breast cancer cases diagnos...

journal_title：Cancer

authors： Winchester DP,Osteen RT,Menck HR

更新日期：1996-10-15 00:00:00

abstract：BACKGROUND:The first step of colorectal carcinoma spread depends on the ability of the tumor cells to degrade and invade the extracellular matrix (ECM). The objectives of the current study were to evaluate the serum pattern of laminin, C-terminal peptide of Type I (PIP), and N-terminal peptide of Type III (PIIIP) proco...

journal_title：Cancer

authors： Plebani M,Basso D,Roveroni G,De Paoli M,Galeotti F,Corsini A

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:There are three distinct types of doxorubicin-induced cardiotoxicity (acute, chronic, and late-onset). Although previous studies with animal models suggest that angiotensin II plays a key role in the process of the doxorubicin-induced cardiotoxicity, there has been no such observation in humans. This randomi...

journal_title：Cancer

authors： Nakamae H,Tsumura K,Terada Y,Nakane T,Nakamae M,Ohta K,Yamane T,Hino M

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:The high mortality associated with ovarian carcinoma is largely a reflection of the inability to diagnose the disease at an early stage; the identification of a histologic lesion or molecular marker associated early stages of transformation would represent an important advance in understanding the natural hi...

journal_title：Cancer

authors： Barakat RR,Federici MG,Saigo PE,Robson ME,Offit K,Boyd J

更新日期：2000-07-15 00:00:00

abstract：:A classification for childhood brain tumors based upon revision of nomenclature of all brain tumors published by the World Health Organization (WHO) in 1979 is proposed. Applicability of the WHO classification scheme was tested in a combined study of the clinical and pathologic features of approximately 3300 brain tum...

journal_title：Cancer

authors： Rorke LB,Gilles FH,Davis RL,Becker LE

更新日期：1985-10-01 00:00:00

abstract：:In certain experimental tumor models, tumor growth is less pronounced in immune deficient animals. Characteristically, tumors such as the murine B16 melanoma and Lewis lung carcinoma (3LL) are weakly antigenic. We proposed that with such tumors that are weakly antigenic, growth is enhanced by T-cell factors. Young mic...

journal_title：Cancer

authors： Ershler WB,Tuck D,Moore AL,Klopp RG,Kramer KE

更新日期：1988-05-01 00:00:00

abstract：:If radical surgery is the only rational policy for most cases of rectal cancer, the problem of local treatment in poor surgical risk patients should be discussed in selected cases. Only limited, fairly-well-differentiated tumors, still confined to the rectal wall may have a sufficiently low probability of lymphatic sp...

journal_title：Cancer

authors： Papillon J

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:In recent years numerous reports have discussed the relationship between the human leukocyte antigen and lung cancer. However, the genetic background of lung cancer has not yet been precisely clarified. METHODS:To investigate the genetic background of lung cancer, the human leukocyte antigens in 159 normal ...

journal_title：Cancer

authors： Shimura T,Hagihara M,Takebe K,Munkhbat B,Odaka T,Kato H,Nagamachi Y,Tsuji K

更新日期：1994-02-15 00:00:00

abstract：BACKGROUND:Oral tongue cancer incidence has increased among whites in the United States; however, the cause remains unknown. If an infectious agent is implicated, then elevated risk would be expected among immunosuppressed individuals. METHODS:By using population-based registry linkage information from the US Transpla...

journal_title：Cancer

authors： Tota JE,Engels EA,Madeleine MM,Clarke CA,Lynch CF,Ortiz AP,Hernandez BY,Chaturvedi AK

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Recent clinical trials support adding ovarian suppression (OS) to oral endocrine therapy (ET) for premenopausal women with early breast cancer. The adoption of OS among real-world populations and the impact of OS on ET adherence have not been evaluated. METHODS:This study examined a retrospective, observati...

journal_title：Cancer

authors： Reeder-Hayes KE,Mayer SE,Lund JL

更新日期：2021-01-28 00:00:00

abstract：:Endoscopic neodymium yttrium aluminium garnet (Nd YAG) laser therapy, is a new and simple method for the palliative treatment of inoperable colorectal cancer. To date the authors have treated 70 patients and the value of this method was assessed prospectively in 14 patients. Quality of life was measured before, during...

journal_title：Cancer

authors： McGowan I,Barr H,Krasner N

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:There is concern that antioxidant supplement use during chemotherapy and radiation therapy may decrease treatment effects, yet the effects of such supplements on recurrence and survival are largely unknown. METHODS:The authors prospectively examined the associations between antioxidant use after breast canc...

journal_title：Cancer

authors： Greenlee H,Kwan ML,Kushi LH,Song J,Castillo A,Weltzien E,Quesenberry CP Jr,Caan BJ

更新日期：2012-04-15 00:00:00

abstract：BACKGROUND:Alpha-interferon and dexamethasone are each effective in patients with multiple myeloma and have a combined inhibitory effect on the in vitro growth of myeloma colonies. The effect of combined therapy in newly diagnosed patients is unknown. METHODS:Fifty-one consecutive patients with previously untreated mu...

journal_title：Cancer

authors： Dimopoulos MA,Weber D,Delasalle KB,Alexanian R

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Positron emission tomography (PET) with labeled fluorodeoxyglucose (FDG) demonstrates increased tracer uptake in many neoplasms. This study was undertaken to define the patterns of FDG uptake in head and neck neoplasms before and after high dose irradiation. METHODS:Twenty-five patients were evaluated prosp...

journal_title：Cancer

authors： Greven KM,Williams DW 3rd,Keyes JW Jr,McGuirt WF,Watson NE Jr,Randall ME,Raben M,Geisinger KR,Cappellari JO

更新日期：1994-08-15 00:00:00

abstract：:The descriptive epidemiologic features of bladder cancer and lung cancer in Los Angeles County were studied for the period 1972-1976, using data from the Los Angeles County/University of Southern California Cancer Surveillance Program. The incidence pattern for bladder cancer was found to differ markedly from the patt...

journal_title：Cancer

authors： Weinberg DM,Ross RK,Mack TM,Paganini-Hill A,Henderson BE

更新日期：1983-02-15 00:00:00

abstract：:Adenoid cystic carcinoma of the esophagus is a relatively rare lesion which characteristically exhibits a clinically aggressive behavior. In spite of this aggressive nature, it is most often referred to as a counterpart of the more common adenoid cystic carcinoma of salivary gland origin, a comparatively indolent tumo...

journal_title：Cancer

authors： Epstein JI,Sears DL,Tucker RS,Eagan JW Jr

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:A randomized, multicenter trial, double-blind for antiandrogen therapy, compared the antiandrogens bicalutamide and flutamide, each combined with luteinizing hormone-releasing hormone analogue therapy (LHRH-A) in 813 patients with Stage D2 prostate carcinoma. An analysis of time to progression (median follow...

journal_title：Cancer

authors： Schellhammer PF,Sharifi R,Block NL,Soloway MS,Venner PM,Patterson AL,Sarosdy MF,Vogelzang NJ,Chen Y,Kolvenbag GJ

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:New biologic prognostic factors are needed to guide the treatment of patients with colorectal cancer. The prognostic value of the altered expression of the cell surface glycoprotein gp78, which has been implicated in tumor-cell invasion and metastasis as an autocrine motility factor (AMF) receptor, was evalu...

journal_title：Cancer

authors： Nakamori S,Watanabe H,Kameyama M,Imaoka S,Furukawa H,Ishikawa O,Sasaki Y,Kabuto T,Raz A

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The Akt/mammalian target of the rapamycin (mTOR) signaling pathway represents a promising target for cancer therapy. The phosphorylation status of Akt and of mTOR's phosphorylation target eukaryotic initiation factor 4E-binding protein 1 (4E-BP1) is often used to assess the activity of Akt and mTOR signaling...

journal_title：Cancer

authors： Akcakanat A,Sahin A,Shaye AN,Velasco MA,Meric-Bernstam F

更新日期：2008-06-01 00:00:00

abstract：:Artificial neural networks now are used in many fields. They have become well established as viable, multipurpose, robust computational methodologies with solid theoretic support and with strong potential to be effective in any discipline, especially medicine. For example, neural networks can extract new medical infor...

journal_title：Cancer

authors： Dayhoff JE,DeLeo JM

更新日期：2001-04-15 00:00:00

abstract：:Based on the independent activity of cisplatin, vinblastine, and dimethyl-triazeno-imidazole-carboxamide (DTIC) (CVD), a combination of these agents was used in the treatment of patients with advanced melanoma. Vinblastine was used in a dose of 1.6 mg/m2/d for 5 days, DTIC was used in a dose of 800 mg/m2 intravenously...

journal_title：Cancer

authors： Legha SS,Ring S,Papadopoulos N,Plager C,Chawla S,Benjamin R

更新日期：1989-11-15 00:00:00

abstract：BACKGROUND:The objective of this study was to determine whether a very low presenting prostate-specific antigen (PSA) level was associated with greater prostate cancer-specific mortality (PCSM) among men with a Gleason score (GS) of 8 to 10. METHODS:The Surveillance, Epidemiology, and End Results program was used to i...

journal_title：Cancer

authors： Mahal BA,Aizer AA,Efstathiou JA,Nguyen PL

更新日期：2016-01-01 00:00:00

abstract：:A short-term differential staining cytotoxicity (DiSC) assay was used to assess the sensitivity of tumor cells in vitro from patients with chronic lymphocytic leukemia (CLL) and non-Hodgkin's lymphoma to various cytotoxic drugs. The results have been correlated with drug sensitivities of the tumors in vivo. The chemos...

journal_title：Cancer

authors： Bird MC,Bosanquet AG,Forskitt S,Gilby ED

更新日期：1988-03-15 00:00:00

abstract：:Amyloid as defined by positive Congo red green birefringence and STB red birefringence was observed in the stroma of a tubular carcinoma of minor salivary gland origin. The amyloid exhibited additional histochemical characteristics of immunamyloid, viz., positive DMAB-nitrate and DC-reactions and spontaneous autofluor...

journal_title：Cancer

authors： David R,Buchner A

更新日期：1978-05-01 00:00:00

abstract：:The ultrastructure of a chondroid syringoma is described. The tumor nests are formed by clumps, solid cords and tubular structures distributed diffusely throughout a stroma of varying density. Two different types of cells form this tumor: dark cells forming the inner layer of the tubuloalveolar and ductal structures a...

journal_title：Cancer

authors： Varela-Durán J,Díaz-Flores L,Varela-Núnez R

更新日期：1979-07-01 00:00:00

abstract：LAY SUMMARY:During the coronavirus disease 2019 (COVID-19) pandemic, cancer screening decreased precipitously; home screening for colorectal cancer diminished less than that for colonoscopy and breast and cervical cancer screening. The authors have highlighted approaches for home cancer screening in addition to telemed...

journal_title：Cancer

authors： Gorin SNS,Jimbo M,Heizelman R,Harmes KM,Harper DM

更新日期：2021-02-15 00:00:00

abstract：:A possible association between gallstones, colorectal cancer, and gastric cancer was investigated. The age distribution and mean age of the two cancer groups were identical. The incidence of gallstones in 378 colorectal cancer cases and 869 gastric cancer cases was 7.1% and 5.5%, respectively. Of colorectal cancer cas...

journal_title：Cancer

authors： Narisawa T,Yamazaki Y,Kusaka H,Takahashi M,Kotanagi H,Koyama K

更新日期：1991-03-15 00:00:00