Utility of molecular genetic signatures in the delineation of gastric neoplasia.

abstract：:Rational treatment of pediatric malignancies requires a detailed knowledge of the clinical pharmacology of those antineoplastic agents used therapeutically. A number of different agents are administered by the oral route. Recently, the clinical pharmacology of 6-mercaptopurine (6-MP) and methotrexate (MTX), the two ag...

journal_title：Cancer

authors： Poplack DG,Balis FM,Zimm S

更新日期：1986-07-15 00:00:00

abstract：:Pericardial effusion and trifascicular block developed 5 years following mediastinal irradiation for Hodgkin's disease in a 19-year-old patient. Another 24-year-old patients had an acute myocardial infarction followed by severe angina pectoris 5 years following mediastinal irradiation for the same disease. A pericardi...

journal_title：Cancer

authors： Ali MK,Kahlil KG,Fuller LM,Leachman RD,Sullivan MP,Loh KK,Gamble JF,Shullenberger CC

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND:The authors recently reported on the role of cyclin E in differentiating ovarian/primary peritoneal carcinoma from malignant peritoneal mesothelioma using gene expression arrays. In the current study, they analyzed the expression of low-molecular weight (LMW) forms of cyclin E in ovarian carcinoma, malignant...

journal_title：Cancer

authors： Davidson B,Skrede M,Silins I,Shih IeM,Trope CG,Flørenes VA

更新日期：2007-09-15 00:00:00

abstract：:The quantitative analysis on glycosaminoglycan (GAG) in the tumor tissues of five patients with malignant pleural mesothelioma and in the pleural fluid of two patients was performed with the use of biochemical methods. In the tumor tissues, it was found that the average of the total amount of GAG was more than 7.9 tim...

journal_title：Cancer

authors： Nakano T,Fujii J,Tamura S,Amuro Y,Nabeshima K,Horai T,Hada T,Higashino K

更新日期：1986-01-01 00:00:00

abstract：:Lymphoid cells from two patients with hand-mirror variant of acute lymphoblastic leukemia (ALL) were studied with various monoclonal antibodies in attempts to determine their derivation and differentiation. The predominant feature of the malignant bone marrow cells was strong reactivity with antibody 3A1, which stains...

journal_title：Cancer

authors： Gramatzki M,Strong DM,Duval-Arnould B,Morstyn G,Schumacher HR

更新日期：1985-01-01 00:00:00

abstract：:The disposition of many drugs in obesity is altered, although little is known of the effect of obesity on the pharmacokinetics of anti-cancer drugs. In this report the authors describe the pharmacokinetics of high-dose methotrexate in an obese woman (184% ideal body weight) with osteosarcoma. For this patient, both th...

journal_title：Cancer

authors： Fleming RA,Eldridge RM,Johnson CE,Stewart CF

更新日期：1991-09-15 00:00:00

abstract：BACKGROUND:Human neoplasms often are accompanied by an inflammatory infiltrate. It has been proposed that this represents an immunologic response to the tumor. Dysgerminoma, a germ cell tumor of the ovary, is a classic example of this phenomenon. The authors investigated the immunophenotype of the tumor-infiltrating ly...

journal_title：Cancer

authors： Dietl J,Horny HP,Ruck P,Kaiserling E

更新日期：1993-04-15 00:00:00

abstract：:A case of coexisting lymphangiosarcoma and Kaposi's sarcoma that occurred in a female renal transplant recipient is presented. Both sarcomas were localized to the skin and were slowly progressive over several years. The coexistence of these two sarcomas may indicate that they arose from a common precursor endothelial ...

journal_title：Cancer

authors： Studniberg HM,Rivers JK,Cooke BE,Barnetson RS

更新日期：1991-11-15 00:00:00

abstract：BACKGROUND:The objective of this study was to define the effects of socioeconomic status (SES) and other demographic variables on outcomes for patients with pancreatic adenocarcinoma. METHODS:Florida cancer registry and inpatient hospital data were queried for pancreatic adenocarcinoma diagnosed from 1998 to 2002. RE...

journal_title：Cancer

authors： Cheung MC,Yang R,Byrne MM,Solorzano CC,Nakeeb A,Koniaris LG

更新日期：2010-02-01 00:00:00

abstract：:A 37-year-old woman with a giant, lymphocytic predominant thymoma involving the pleura and accompanied by a sharp peripheral blood lymphocytosis is described. Only electromicroscopic and immunohistologic studies could exclude the alternative diagnosis of mediastinal lymphoma. The tumor and peripheral blood lymphocytes...

journal_title：Cancer

authors： Shachor Y,Radnay J,Bernheim J,Rozenszajn A,Bruderman I,Klajman A,Steiner ZP

更新日期：1988-03-15 00:00:00

abstract：BACKGROUND:Surgery alone is the appropriate first-line treatment for patients with mesoblastic nephroma (MN). Nevertheless, there are reports of local recurrences and metastasis, especially in the cellular subtype. The authors evaluated the outcome of patients with MN who were enrolled in either the International Socie...

journal_title：Cancer

authors： Furtwaengler R,Reinhard H,Leuschner I,Schenk JP,Goebel U,Claviez A,Kulozik A,Zoubek A,von Schweinitz D,Graf N,Gesellschaft fur Pädiatrische Onkologie und Hämatologie (GPOH) Nephroblastoma Study Group.

更新日期：2006-05-15 00:00:00

abstract：BACKGROUND:Glembatumumab vedotin is an antibody-drug conjugate that produced preliminary clinical activity against advanced melanoma in a phase 1 dose-escalation trial. The objective of the current study was to investigate further the antitumor activity of glembatumumab vedotin at the recommended phase 2 dose in heavil...

journal_title：Cancer

authors： Ott PA,Pavlick AC,Johnson DB,Hart LL,Infante JR,Luke JJ,Lutzky J,Rothschild NE,Spitler LE,Cowey CL,Alizadeh AR,Salama AK,He Y,Hawthorne TR,Bagley RG,Zhang J,Turner CD,Hamid O

更新日期：2019-04-01 00:00:00

abstract：:It is justifiable to assume that a spontaneous regression of cervical intraepithelial neoplasia is in progress when pathologic epithelium is replaced by normal epithelium. Very rare histologic pictures of this process are shown. Dysplastic squamous epithelium or intraepithelial carcinomas become detached from their ba...

journal_title：Cancer

authors： Bajardi F

更新日期：1984-08-15 00:00:00

abstract：:In order to quantify the lymphocyte to epithelial cell ratio (L/E ratio of the thymoma, actual counting was performed. The L/E ratio was investigated in 25 specimens of 22 cases (22 initial tumors and 3 recurrent tumors). L/E ratios ranged from 0.27 to 4.10, and the mean value was 1.93 +/- 0.21. The mean L/E ratio of ...

journal_title：Cancer

authors： Masaoka A,Nagaoka Y,Maeda M,Monden Y,Seike Y

更新日期：1977-09-01 00:00:00

abstract：:Most patients with colorectal carcinoma undergo attempts at curative surgery. However, some present with metastatic disease and many others ultimately relapse. Most recurrences of colorectal cancer are not resectable and require nonsurgical approaches such as chemotherapy and radiation therapy directed against local r...

journal_title：Cancer

authors： Vaughn DJ,Haller DG

更新日期：1993-06-15 00:00:00

abstract：BACKGROUND:The effect of aspirin use on 490 patients with cancer of the colon, 340 with cancer of the rectum as the first primary site, and 212 patients with polyps having no coexisting malignancies was compared with that of two groups of control subjects that consisted of 524 hospital patients having no cancers and no...

journal_title：Cancer

authors： Suh O,Mettlin C,Petrelli NJ

更新日期：1993-08-15 00:00:00

abstract：BACKGROUND:Carcinomas of the small intestine are rare, but the risk is greatly increased in patients with hereditary nonpolyposis colorectal cancer (HNPCC) due to an inherited mismatch repair (MMR) gene mutation, most commonly affecting the genes MLH1 or MSH2. Defective MMR is characterized by microsatellite instabilit...

journal_title：Cancer

authors： Planck M,Ericson K,Piotrowska Z,Halvarsson B,Rambech E,Nilbert M

更新日期：2003-03-15 00:00:00

abstract：BACKGROUND:Low frequency epithelial cells in bone marrow from colorectal carcinoma patients are associated with an increased risk of recurrence and decreased survival. Current immunohistochemical approaches to detect epithelial cells in bone marrow aspirates rely on antibodies against cytokeratin 18 (CK18). The predict...

journal_title：Cancer

authors： Litle VR,Warren RS,Moore D 2nd,Pallavicini MG

更新日期：1997-05-01 00:00:00

abstract：BACKGROUND:A randomized, multicenter trial, double-blind for antiandrogen therapy, compared the antiandrogens bicalutamide and flutamide, each combined with luteinizing hormone-releasing hormone analogue therapy (LHRH-A) in 813 patients with Stage D2 prostate carcinoma. An analysis of time to progression (median follow...

journal_title：Cancer

authors： Schellhammer PF,Sharifi R,Block NL,Soloway MS,Venner PM,Patterson AL,Sarosdy MF,Vogelzang NJ,Chen Y,Kolvenbag GJ

更新日期：1996-11-15 00:00:00

abstract：:A 17-year-old girl was operated for a solitary well-circumscribed pulmonary parenchymal tumor and reoperated ten times for multiple recurrent similar pulmonary tumors during 24 years. Histologic examination revealed the so-called intravascular bronchioloalveolar tumor (IVBAT) in all instances. The patient died from pn...

journal_title：Cancer

authors： Miettinen M,Collan Y,Halttunen P,Maamies T,Vilkko P

更新日期：1987-11-15 00:00:00

abstract：BACKGROUND:Although pediatric cancer mortality and survival have improved in the United States over the past 40 years, differences exist by age, race/ethnicity, cancer site, and economic status. To assess progress, this study examined recent mortality and survival data for individuals younger than 20 years. METHODS:Ag...

journal_title：Cancer

authors： Siegel DA,Richardson LC,Henley SJ,Wilson RJ,Dowling NF,Weir HK,Tai EW,Buchanan Lunsford N

更新日期：2020-10-01 00:00:00

abstract：:The hepatic histopathology was studied in 125 patients with Hodgkin's disease to determine whether there are any features other than Reed-Sternberg (RS) cells that might aid in the diagnosis of hepatic involvement by the neoplastic process. Liver biopsy specimens from 41 patients with Hodgkin's disease in the liver we...

journal_title：Cancer

authors： Dich NH,Goodman ZD,Klein MA

更新日期：1989-11-15 00:00:00

abstract：BACKGROUND:Cancer patients with single tumors live longer today due to earlier detection and improved treatment methods. For this reason, the authors see more patients who develop a second primary tumor. The etiology of the second tumor can be the same as the first, whether treatment-induced or unknown. The prognoses o...

journal_title：Cancer

authors： Robinson E,Segal R,Struminger L,Faraggi D,El'ad-Yarum R,Mekori T

更新日期：1999-05-01 00:00:00

abstract：:Twenty-two patients who previously responded to first-line hormonal therapy were evaluated for factors which would predict for response to second hormonal manipulation. Investigations performed at progression after initial hormone response included immunocytochemical estimation of estrogen and progesterone receptors a...

journal_title：Cancer

authors： Seymour L,Bezwoda WR,Meyer K

更新日期：1990-06-15 00:00:00

abstract：:The identification of important prognostic factors at diagnosis of childhood leukemia has been very useful in explaining the marked differences in disease outcome. After a complete remission is achieved, it is interesting to determine whether the ability to maintain a complete remission and the patient's survival cont...

journal_title：Cancer

authors： Sather H,Coccia P,Nesbit M,Level C,Hammond D

更新日期：1981-07-15 00:00:00

abstract：BACKGROUND:To eliminate cranial irradiation (CrRT)-related sequelae and to minimize the adverse impact of traumatic lumbar puncture (TLP) with blasts, the Taiwan Pediatric Oncology Group (TPOG) introduced a modified central nervous system (CNS)-directed regimen characterized by delayed triple intrathecal therapy (TIT) ...

journal_title：Cancer

authors： Yeh TC,Liang DC,Hou JY,Jaing TH,Lin DT,Yang CP,Peng CT,Hung IJ,Lin KH,Hsiao CC,Jou ST,Chiou SS,Chen JS,Wang SC,Chang TK,Wu KH,Sheen JM,Yen HJ,Chen SH,Lu MY,Li MJ,Chang TT,Huang TH,Chang YH,Chen SH,Yang Y

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:Primary small cell carcinoma arising in organs other than the lung were thought to be relatively rare. However, with the increasing technical sophistication of pathology departments, tumors with foci of small cell neuroendocrine components are being identified more frequently. The pattern of disease involvem...

journal_title：Cancer

authors： Lyster MT,Kies MS,Kuzel TM

更新日期：1994-12-15 00:00:00

abstract：BACKGROUND:Conflicting results have been obtained regarding blood flow distribution to liver tumors. The emphasis on portal vein perfusion has had a great impact on the design of treatment protocols. METHODS:Double microsphere technique with reference organ sampling was used for the measurement of hepatic artery and p...

journal_title：Cancer

authors： Wang LQ,Persson BG,Bergqvist L,Bengmark S

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:TRAIL (tumor necrosis factor related apoptosis-inducing ligand) is involved in tumor immune surveillance and, thus, may be a potential cancer therapy. TRAIL expression in the tumor microenvironment has been shown to impact cancer survival in multiple tumor types, including ovarian cancer. We studied TRAIL ex...

journal_title：Cancer

authors： Anees M,Horak P,El-Gazzar A,Susani M,Heinze G,Perco P,Loda M,Lis R,Krainer M,Oh WK

更新日期：2011-03-15 00:00:00

abstract：BACKGROUND:Introduction of human papillomavirus (HPV) vaccination for adolescent girls is being considered in the Punjab state of India. However, evidence regarding cost-effectiveness is sought by policy makers when making this decision. The current study was undertaken to evaluate the incremental cost per quality-adju...

journal_title：Cancer

authors： Prinja S,Bahuguna P,Faujdar DS,Jyani G,Srinivasan R,Ghoshal S,Suri V,Singh MP,Kumar R

更新日期：2017-09-01 00:00:00