The natural five-year course in bronchial carcinoma. Epidemiologic results.

abstract：BACKGROUND:Myeloma survival varies markedly with International Staging System classification, presence of cytogenetic abnormalities, and, especially, gene expression profiling-based risk and delTP53 status, whose collective impact has not been examined in the context of specific therapies. METHODS:The authors examined...

journal_title：Cancer

authors： Waheed S,Shaughnessy JD,van Rhee F,Alsayed Y,Nair B,Anaissie E,Szymonifka J,Hoering A,Crowley J,Barlogie B

更新日期：2011-03-01 00:00:00

abstract：:The occurrence and staining patterns of Concanavalin A (Con A) binding histiocytes were studied in diagnostic lymph node specimens of 133 patients with Hodgkin's disease. Varying numbers of Con A binding histiocytes were present in all tumors. Two distinct cytoplasmic staining patterns of the Con A binding histiocytes...

journal_title：Cancer

authors： Ree HJ,Crowley JP

更新日期：1983-07-15 00:00:00

abstract：BACKGROUND:The authors studied the benefit of performing histopathologic grading and DNA ploidy characterization with respect to patient survival in a series of 206 astrocytomas (AST) for which they obtained 134 complete clinical follow-ups. METHODS:The material analyzed came from archival material, i.e., formalin-fix...

journal_title：Cancer

authors： Salmon I,Kiss R,Dewitte O,Gras T,Pasteels JL,Brotchi J,Flament-Durand J

更新日期：1992-07-15 00:00:00

abstract：BACKGROUND:Patients with multiple myeloma (MM) have increased bone marrow angiogenesis, a low plasma cell labeling index, and multidrug resistance (the primary cause of chemotherapy failure). MM patients receiving the vincristine, doxorubicin, and dexamethasone (VAD) regimen develop resistance and cardiac and steroid t...

journal_title：Cancer

authors： Hussein MA,Wood L,Hsi E,Srkalovic G,Karam M,Elson P,Bukowski RM

更新日期：2002-11-15 00:00:00

abstract：BACKGROUND:Primary malignant splenic neoplasms are rare tumors. Apart from involvement of the spleen by malignant lymphoma, hemangiosarcoma is the most common form of primary malignant neoplasm in the spleen. The diagnosis often is made at autopsy or after spontaneous splenic rupture. The prognosis is usually poor, and...

journal_title：Cancer

authors： Søndenaa K,Heikkilä R,Nysted A,Søreide JA,Odegaard H,Pollard ML,Holter J

更新日期：1993-01-01 00:00:00

abstract：:Data on patients with gallbladder cancer listed in the Surveillance, Epidemiology, and End Results (SEER) Program of the National Cancer Institute were reviewed. Between 1977 and 1986, 3038 patients were recorded in the Program. Histologic grade, histologic type, stage of disease, and vascular invasion were correlated...

journal_title：Cancer

authors： Henson DE,Albores-Saavedra J,Corle D

更新日期：1992-09-15 00:00:00

abstract：BACKGROUND:Some patients with chronic myeloid leukemia (CML) have a history of previous malignancies. To the authors' knowledge, outcomes for CML diagnosed in these patients have not been well described. The current study was conducted to determine the outcome of patients with CML and a history of prior malignancies. ...

journal_title：Cancer

authors： Koller PB,Kantarjian HM,Nogueras-Gonzalez GM,Jabbour E,Verstovsek S,Borthakur G,Estrov Z,Wierda WG,Garcia-Manero G,Ferrajoli A,Ravandi F,O'Brien SM,Cortes JE

更新日期：2017-02-15 00:00:00

abstract：BACKGROUND:Langerhans cell histiocytosis (LCH) is a rare myeloid neoplasm characterized by the presence of abnormal CD1a-positive (CD1a+ )/CD207+ histiocytes. Hemophagocytic lymphohistiocytosis (HLH) represents a spectrum of hyperinflammatory syndromes typified by the dysregulated activation of the innate and adaptive ...

journal_title：Cancer

authors： Chellapandian D,Hines MR,Zhang R,Jeng M,van den Bos C,Santa-María López V,Lehmberg K,Sieni E,Wang Y,Nakano T,Williams JA,Fustino NJ,Astigarraga I,Dunkel IJ,Abla O,van Halteren AGS,Pei D,Cheng C,Weitzman S,Sung L,N

更新日期：2019-03-15 00:00:00

abstract：BACKGROUND:Fadrozole hydrochloride (CGS 16949A) is a highly potent, nonsteroidal aromatase inhibitor that significantly lowers estrogen levels in postmenopausal women and can be effective therapy for patients with advanced hormone-dependent breast carcinoma. Circulating estradiol, estrone, and estrone sulfate are reduc...

journal_title：Cancer

authors： Costa LA,Kopreski MS,Demers LM,Chinchilli VM,Santen RJ,Harvey HA,Lipton A

更新日期：1999-01-01 00:00:00

abstract：:Transthoracic fine needle aspiration (FNA) biopsies performed under computed tomography (CT) scan (CT-FNA) have greatly improved the cytodiagnosis of lung tumors. However, the distinction between a primary lesion and a metastatic lesion still may be difficult on the basis of morphologic criteria. To evaluate whether a...

journal_title：Cancer

authors： Mottolese M,Venturo I,Rinaldi M,Campioni N,Aluffi A,Curcio CG,Donnorso RP,Natali PG

更新日期：1989-12-15 00:00:00

abstract：BACKGROUND:Onycholysis has been reported in association with the use of several noncytotoxic drugs and with chemotherapy in 135 patients. Onycholysis may be precipitated by exposure to ultraviolet radiation. METHODS:The authors studied 91 patients who received paclitaxel and 187 patients who received doxorubicin. RES...

journal_title：Cancer

authors： Hussain S,Anderson DN,Salvatti ME,Adamson B,McManus M,Braverman AS

更新日期：2000-05-15 00:00:00

abstract：:An Epstein-Barr virus (EBV)-negative lymphoma line (JBL) was established in vitro from pleural effusion of an EBV-seropositive 29-year-old Japanese female with Burkitt's lymphoma. JBL cells as well as her original lymphoma cells bore monoclonal surface IgM with lambda light chains. The JBL line grew in single cell sus...

journal_title：Cancer

authors： Miyoshi I,Hiraki S,Kubonishi I,Matsuda Y,Kishimoto H,Nakayama T,Tanaka T,Masuji H,Kimura I

更新日期：1977-12-01 00:00:00

abstract：BACKGROUND:The effect of p53 protein expression and MIB-1 proliferative activity on survival and chemotherapeutic response in patients with lymph node (LN)-positive transitional cell carcinoma (TCC) of the urinary bladder remains unclear. The objective of this study was to assess the ability of these markers to predict...

journal_title：Cancer

authors： Frank I,Cheville JC,Blute ML,Lohse CM,Karnes RJ,Weaver AL,Sebo TJ,Nehra A,Zincke H

更新日期：2004-10-15 00:00:00

abstract：BACKGROUND:From 1973 to 1991, the incidence of kidney cancer in the United States increased by 35.4%. METHODS:A multicenter, hospital-based case-control study was conducted from 1977 to 1993 through an interview of 788 patients with renal cell carcinoma and 779 control subjects. RESULTS:Compared with those who never ...

journal_title：Cancer

authors： Muscat JE,Hoffmann D,Wynder EL

更新日期：1995-05-15 00:00:00

abstract：:Elective irradiation of sites of potential occult tumor spread is often part of a patient's radiation therapy program. The required radiation dose (D) depends on the probability that occult disease exists (P(occ)), the number of sites at risk (A), the number of tumor clonogens present (Ni), their radiation sensitivity...

journal_title：Cancer

authors： Marks LB

更新日期：1990-12-15 00:00:00

abstract：:An astroblastoma in the cerebrum was investigated with the electron microscope. A distinctive feature of the tumor was the radial arrangement of astrocytic cells around the blood vessels. The blood vessels in the tumor commonly exhibited fenestrated endothelial cells. The endothelium was generally surrounded by lamell...

journal_title：Cancer

authors： Kubota T,Hirano A,Sato K,Yamamoto S

更新日期：1985-02-15 00:00:00

abstract：BACKGROUND:The authors evaluated the effects of taxol, a microtubular inhibitor, as a possible radiation sensitizer on the human leukemic cell line (HL-60). Taxol acts as a mitotic inhibitor, blocking cells in the G2M-phase of the cell cycle. The differential radiation sensitivity of cells in various phases of the cell...

journal_title：Cancer

authors： Choy H,Rodriguez FF,Koester S,Hilsenbeck S,Von Hoff DD

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:The clinical features and natural history of adrenocortical carcinoma are highly dependent on the type of center reporting their experience. Observations from oncology services suggest a high incidence of nonfunctioning tumors, whereas reports from endocrine clinics emphasize excessive corticoid and androgen...

journal_title：Cancer

authors： Wajchenberg BL,Albergaria Pereira MA,Medonca BB,Latronico AC,Campos Carneiro P,Alves VA,Zerbini MC,Liberman B,Carlos Gomes G,Kirschner MA

更新日期：2000-02-15 00:00:00

abstract：BACKGROUND:Previous studies have shown that matrix metalloproteinase-2 (MMP-2) (a 72-kilodalton Type IV collagenase/gelatinase A) is associated with breast carcinoma, but to the authors' knowledge there are no reports showing that it is prognostic for overall survival. METHODS:Expression of the immunoreactive protein ...

journal_title：Cancer

authors： Talvensaari-Mattila A,Pääkkö P,Höyhtyä M,Blanco-Sequeiros G,Turpeenniemi-Hujanen T

更新日期：1998-09-15 00:00:00

abstract：BACKGROUND:The authors report the results of a prospective study of patients with malignant neuroendocrine tumors of the sinonasal tract who received multimodality treatment incorporating high-dose proton-photon radiotherapy. METHODS:Nineteen patients with olfactory neuroblastoma (ONB) or neuroendocrine carcinoma (NEC...

journal_title：Cancer

authors： Fitzek MM,Thornton AF,Varvares M,Ancukiewicz M,Mcintyre J,Adams J,Rosenthal S,Joseph M,Amrein P

更新日期：2002-05-15 00:00:00

abstract：:The properties of two classes of nonhistone nuclear proteins (NHNP) whose appearance has been correlated with the process of carcinogenesis in the colonic epithelium of rats given 1,2-dimethylhydrazine (DMH) have been investigated. NHNP isolated from adenocarcinomas of the colon were tested for their binding to homolo...

journal_title：Cancer

authors： Boffa LC,Allfrey VG

更新日期：1977-11-01 00:00:00

abstract：:Major findings are presented from a workshop on Quality of Life Assessment in Cancer Symptom Management Trials, sponsored by the National Cancer Institute. Data-driven research reports focused on 3 topics, 1) the rationale and utility of health-related quality of life (HRQOL) assessment, 2) conceptual models, and 3) m...

journal_title：Cancer

authors： Buchanan DR,O'Mara AM,Kelaghan JW,Sgambati M,McCaskill-Stevens W,Minasian L

更新日期：2007-10-01 00:00:00

abstract：:Eighteen patients with isolated vaginal recurrence of their previously treated endometrial carcinoma were treated with radiation therapy at North Carolina Baptist Hospital, Winston-Salem between 1971 and 1982. Most patients received external beam irradiation which were followed by boost treatments that were delivered ...

journal_title：Cancer

authors： Greven K,Olds W

更新日期：1987-08-01 00:00:00

abstract：:The continuity that exists between Hodgkin's disease and the fibrohistiocytoses has only recently been recognized. Four cases are presented that illustrate this phenomenon. The fibrohistiocytic component of the Hodgkin's lesion may lag behind the lymphoreticular component, may be present in equal proportion, or may as...

journal_title：Cancer

authors： Suster S

更新日期：1986-01-15 00:00:00

abstract：:Since 1975, the Department of Radiation Therapy, University of Maryland Hospital initiated a policy of supplementing the dose to the affected parametrium by using radium needles implants in conjunction with a protruding tandem preferably, or Manchester ovoid in the case of absence of the lower segment of the uterus. T...

journal_title：Cancer

authors： Prempree T

更新日期：1983-08-15 00:00:00

abstract：:Measurement of the alpha 1 (fast liver) fraction of alkaline phosphatases in the serum for 217 cancer patients, 92 patients with nonmalignant hepatic affections and 131 controls, revealed that the alpha 1 fraction offers better global value (94%), sensitivity (96%), and specificity (93%) than gamma GT or total alkalin...

journal_title：Cancer

authors： Viot M,Thyss A,Schneider M,Viot G,Ramaioli A,Cambon P,Lalanne CM

更新日期：1983-07-01 00:00:00

abstract：BACKGROUND:To the authors' knowledge, the empiric identification of agents and interventions to mitigate chemotherapy-induced peripheral neuropathy (CIPN) has resulted in only 1 agent that modestly mitigates it and no agents or interventions that prevent its development. This speaks to the need for a mechanistic unders...

journal_title：Cancer

authors： St Germain DC,O'Mara AM,Robinson JL,Torres AD,Minasian LM

更新日期：2020-10-15 00:00:00

abstract：BACKGROUND:CD133 is a specific surface marker for bone marrow-derived circulating endothelial progenitors, which are vital in postnatal physiologic and pathologic (eg, tumor) angiogenesis. In this study, the authors examined whether increased levels of expression of CD133 messenger RNA (mRNA) in peripheral blood predic...

journal_title：Cancer

authors： Lin EH,Hassan M,Li Y,Zhao H,Nooka A,Sorenson E,Xie K,Champlin R,Wu X,Li D

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:There are large geographic gradients in mortality rates for a number of cancers in the U.S. (e.g., rates are approximately twice as high in the northeast compared with the southwest). Risk factors such as diet fail to explain this variation. Previous studies have demonstrated that the geographic distribution...

journal_title：Cancer

authors： Grant WB

更新日期：2002-03-15 00:00:00

abstract：:The use of preoperative computed tomographic (CT) scans of the chest in carcinoma of the esophagus to associate preoperative staging with postoperative survival is controversial. Thirty-two patients who underwent esophagectomy and reconstruction were examined with respect to a variety of variables available on preoper...

journal_title：Cancer

authors： Lefor AT,Merino MM,Steinberg SM,Dwyer A,Roth JA,Flanagan M,Pass HI

更新日期：1988-10-01 00:00:00